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Items: 35

1.

A luminal EF-hand mutation in STIM1 in mice causes the clinical hallmarks of tubular aggregate myopathy.

Cordero-Sanchez C, Riva B, Reano S, Clemente N, Zaggia I, Ruffinatti FA, Potenzieri A, Pirali T, Raffa S, Sangaletti S, Colombo MP, Bertoni A, Garibaldi M, Filigheddu N, Genazzani AA.

Dis Model Mech. 2019 Dec 3;13(2). pii: dmm041111. doi: 10.1242/dmm.041111.

2.

Vitamin D as a Biomarker of Ill Health among the Over-50s: A Systematic Review of Cohort Studies.

Caristia S, Filigheddu N, Barone-Adesi F, Sarro A, Testa T, Magnani C, Aimaretti G, Faggiano F, Marzullo P.

Nutrients. 2019 Oct 6;11(10). pii: E2384. doi: 10.3390/nu11102384. Review.

3.

Identification of Haptoglobin as a Readout of rhGH Therapy in GH Deficiency.

De Feudis M, Walker GE, Genoni G, Manfredi M, Agosti E, Giordano M, Caputo M, Di Trapani L, Marengo E, Aimaretti G, Filigheddu N, Bellone S, Bona G, Prodam F.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5263-5273. doi: 10.1210/jc.2019-00562.

PMID:
31215990
4.

Opposing effects of 25-hydroxy- and 1α,25-dihydroxy-vitamin D3 on pro-cachectic cytokine-and cancer conditioned medium-induced atrophy in C2C12 myotubes.

Sustova H, De Feudis M, Reano S, Alves Teixeira M, Valle I, Zaggia I, Agosti E, Prodam F, Filigheddu N.

Acta Physiol (Oxf). 2019 Jul;226(3):e13269. doi: 10.1111/apha.13269. Epub 2019 Mar 19.

PMID:
30834670
5.

Ghrelin knockout mice display defective skeletal muscle regeneration and impaired satellite cell self-renewal.

Angelino E, Reano S, Bollo A, Ferrara M, De Feudis M, Sustova H, Agosti E, Clerici S, Prodam F, Tomasetto CL, Graziani A, Filigheddu N.

Endocrine. 2018 Oct;62(1):129-135. doi: 10.1007/s12020-018-1606-4. Epub 2018 May 30.

PMID:
29846901
6.

Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.

Wyart E, Reano S, Hsu MY, Longo DL, Li M, Hirsch E, Filigheddu N, Ghigo A, Riganti C, Porporato PE.

Oxid Med Cell Longev. 2018 Feb 26;2018:6419805. doi: 10.1155/2018/6419805. eCollection 2018.

7.

Mitochondrial metabolism and cancer.

Porporato PE, Filigheddu N, Pedro JMB, Kroemer G, Galluzzi L.

Cell Res. 2018 Mar;28(3):265-280. doi: 10.1038/cr.2017.155. Epub 2017 Dec 8. Review.

8.

The role of vitamin D in cancer cachexia.

Penna F, Camperi A, Muscaritoli M, Filigheddu N, Costelli P.

Curr Opin Support Palliat Care. 2017 Dec;11(4):287-292. doi: 10.1097/SPC.0000000000000302. Review.

PMID:
28922293
9.

Unacylated Ghrelin Enhances Satellite Cell Function and Relieves the Dystrophic Phenotype in Duchenne Muscular Dystrophy mdx Model.

Reano S, Angelino E, Ferrara M, Malacarne V, Sustova H, Sabry O, Agosti E, Clerici S, Ruozi G, Zentilin L, Prodam F, Geuna S, Giacca M, Graziani A, Filigheddu N.

Stem Cells. 2017 Jul;35(7):1733-1746. doi: 10.1002/stem.2632. Epub 2017 May 7.

10.

Unacylated Ghrelin Reduces Skeletal Muscle Reactive Oxygen Species Generation and Inflammation and Prevents High-Fat Diet-Induced Hyperglycemia and Whole-Body Insulin Resistance in Rodents.

Gortan Cappellari G, Zanetti M, Semolic A, Vinci P, Ruozi G, Falcione A, Filigheddu N, Guarnieri G, Graziani A, Giacca M, Barazzoni R.

Diabetes. 2016 Apr;65(4):874-86. doi: 10.2337/db15-1019. Epub 2016 Jan 28.

11.

Correction: Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential.

Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, Merlin S, Talmon M, Novelli E, Diena M, Nicoletti C, Musarò A, Filigheddu N, Follenzi A, Prat M.

PLoS One. 2015 Oct 23;10(10):e0141632. doi: 10.1371/journal.pone.0141632. eCollection 2015. No abstract available.

12.

Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential.

Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, Merlin S, Talmon M, Novelli E, Diena M, Nicoletti C, Musarò A, Filigheddu N, Follenzi A, Prat M.

PLoS One. 2015 Sep 16;10(9):e0137999. doi: 10.1371/journal.pone.0137999. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0141632.

13.

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia.

Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, Zentilin L, Filigheddu N, Gortan Cappellari G, Baldini G, Zweyer M, Barazzoni R, Graziani A, Zacchigna S, Giacca M.

Nat Commun. 2015 Jun 11;6:7388. doi: 10.1038/ncomms8388.

14.

Antifibrotic activity of acylated and unacylated ghrelin.

Angelino E, Reano S, Ferrara M, Agosti E, Graziani A, Filigheddu N.

Int J Endocrinol. 2015;2015:385682. doi: 10.1155/2015/385682. Epub 2015 Apr 16. Review.

15.

The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.

Rainero E, Cianflone C, Porporato PE, Chianale F, Malacarne V, Bettio V, Ruffo E, Ferrara M, Benecchia F, Capello D, Paster W, Locatelli I, Bertoni A, Filigheddu N, Sinigaglia F, Norman JC, Baldanzi G, Graziani A.

PLoS One. 2014 Jun 2;9(6):e97144. doi: 10.1371/journal.pone.0097144. eCollection 2014.

16.

Ghrelin gene products in acute and chronic inflammation.

Prodam F, Filigheddu N.

Arch Immunol Ther Exp (Warsz). 2014 Oct;62(5):369-84. doi: 10.1007/s00005-014-0287-9. Epub 2014 Apr 12. Review.

PMID:
24728531
17.

Acylated and unacylated ghrelin administration to blunt muscle wasting.

Reano S, Graziani A, Filigheddu N.

Curr Opin Clin Nutr Metab Care. 2014 May;17(3):236-40. doi: 10.1097/MCO.0000000000000049. Review.

PMID:
24572833
18.

Ghrelin: a novel neuromuscular recovery promoting factor?

Raimondo S, Ronchi G, Geuna S, Pascal D, Reano S, Filigheddu N, Graziani A.

Int Rev Neurobiol. 2013;108:207-21. doi: 10.1016/B978-0-12-410499-0.00008-3. Review.

PMID:
24083436
19.

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.

Porporato PE, Filigheddu N, Reano S, Ferrara M, Angelino E, Gnocchi VF, Prodam F, Ronchi G, Fagoonee S, Fornaro M, Chianale F, Baldanzi G, Surico N, Sinigaglia F, Perroteau I, Smith RG, Sun Y, Geuna S, Graziani A.

J Clin Invest. 2013 Feb;123(2):611-22. doi: 10.1172/JCI39920. Epub 2013 Jan 2.

20.

SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, Chianale F, Porporato PE, Filigheddu N, Mesturini R, Song S, Schweighoffer T, Patrussi L, Baldari CT, Zhong XP, van Blitterswijk WJ, Sinigaglia F, Nichols KE, Rubio I, Parolini O, Graziani A.

J Immunol. 2011 Dec 1;187(11):5941-51. doi: 10.4049/jimmunol.1002476. Epub 2011 Nov 2.

21.

Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30.

Filigheddu N, Sampietro S, Chianale F, Porporato PE, Gaggianesi M, Gregnanin I, Rainero E, Ferrara M, Perego B, Riboni F, Baldanzi G, Graziani A, Surico N.

Cell Signal. 2011 Dec;23(12):1988-96. doi: 10.1016/j.cellsig.2011.07.009. Epub 2011 Jul 22.

PMID:
21802511
22.

Diacylglycerol kinases are essential for hepatocyte growth factor-dependent proliferation and motility of Kaposi's sarcoma cells.

Baldanzi G, Pietronave S, Locarno D, Merlin S, Porporato P, Chianale F, Filigheddu N, Cantelmo AR, Albini A, Graziani A, Prat M.

Cancer Sci. 2011 Jul;102(7):1329-36. doi: 10.1111/j.1349-7006.2011.01953.x. Epub 2011 May 18.

23.

Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis.

Filigheddu N, Gregnanin I, Porporato PE, Surico D, Perego B, Galli L, Patrignani C, Graziani A, Surico N.

J Biomed Biotechnol. 2010;2010:369549. doi: 10.1155/2010/369549. Epub 2010 Mar 10.

24.

Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.

Chianale F, Rainero E, Cianflone C, Bettio V, Pighini A, Porporato PE, Filigheddu N, Serini G, Sinigaglia F, Baldanzi G, Graziani A.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4182-7. doi: 10.1073/pnas.0908326107. Epub 2010 Feb 16.

25.

Morphological and biomolecular characterization of the neonatal olfactory bulb ensheathing cell line.

Audisio C, Raimondo S, Nicolino S, Gambarotta G, Di Scipio F, Macrì L, Montarolo F, Giacobini-Robecchi MG, Porporato P, Filigheddu N, Graziani A, Geuna S, Perroteau I.

J Neurosci Methods. 2009 Dec 15;185(1):89-98. doi: 10.1016/j.jneumeth.2009.09.021. Epub 2009 Sep 26.

26.

Calcium signals activated by ghrelin and D-Lys(3)-GHRP-6 ghrelin antagonist in developing dorsal root ganglion glial cells.

Erriquez J, Bernascone S, Ciarletta M, Filigheddu N, Graziani A, Distasi C.

Cell Calcium. 2009 Sep;46(3):197-208. doi: 10.1016/j.ceca.2009.07.003. Epub 2009 Aug 7.

PMID:
19665224
27.

Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling.

Chianale F, Cutrupi S, Rainero E, Baldanzi G, Porporato PE, Traini S, Filigheddu N, Gnocchi VF, Santoro MM, Parolini O, van Blitterswijk WJ, Sinigaglia F, Graziani A.

Mol Biol Cell. 2007 Dec;18(12):4859-71. Epub 2007 Sep 26.

28.

Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.

Baldanzi G, Cutrupi S, Chianale F, Gnocchi V, Rainero E, Porporato P, Filigheddu N, van Blitterswijk WJ, Parolini O, Bussolino F, Sinigaglia F, Graziani A.

Oncogene. 2008 Feb 7;27(7):942-56. Epub 2007 Aug 13.

PMID:
17700527
29.

Diacylglycerol kinase is required for HGF-induced invasiveness and anchorage-independent growth of MDA-MB-231 breast cancer cells.

Filigheddu N, Cutrupi S, Porporato PE, Riboni F, Baldanzi G, Chianale F, Fortina E, Piantanida P, De Bortoli M, Vacca G, Graziani A, Surico N.

Anticancer Res. 2007 May-Jun;27(3B):1489-92.

30.

Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.

Filigheddu N, Gnocchi VF, Coscia M, Cappelli M, Porporato PE, Taulli R, Traini S, Baldanzi G, Chianale F, Cutrupi S, Arnoletti E, Ghè C, Fubini A, Surico N, Sinigaglia F, Ponzetto C, Muccioli G, Crepaldi T, Graziani A.

Mol Biol Cell. 2007 Mar;18(3):986-94. Epub 2007 Jan 3.

31.

p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis.

Coltella N, Rasola A, Nano E, Bardella C, Fassetta M, Filigheddu N, Graziani A, Comoglio PM, Di Renzo MF.

Int J Cancer. 2006 Jun 15;118(12):2981-90.

32.

Role of phosphatidylinositol 3-kinase in the development of hepatocyte preconditioning.

Carini R, Grazia De Cesaris M, Splendore R, Baldanzi G, Nitti MP, Alchera E, Filigheddu N, Domenicotti C, Pronzato MA, Graziani A, Albano E.

Gastroenterology. 2004 Sep;127(3):914-23.

PMID:
15362046
33.

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro.

Baldanzi G, Mitola S, Cutrupi S, Filigheddu N, van Blitterswijk WJ, Sinigaglia F, Bussolino F, Graziani A.

Oncogene. 2004 Jun 17;23(28):4828-38.

PMID:
15122338
34.

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, Malan D, Baj G, Granata R, Broglio F, Papotti M, Surico N, Bussolino F, Isgaard J, Deghenghi R, Sinigaglia F, Prat M, Muccioli G, Ghigo E, Graziani A.

J Cell Biol. 2002 Dec 23;159(6):1029-37. Epub 2002 Dec 16.

35.

Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death.

Filigheddu N, Fubini A, Baldanzi G, Cutrupi S, Ghè C, Catapano F, Broglio F, Bosia A, Papotti M, Muccioli G, Ghigo E, Deghenghi R, Graziani A.

Endocrine. 2001 Feb;14(1):113-9.

PMID:
11322493

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