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Items: 1 to 50 of 120

1.

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue.

Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, Eisenhaure TM, Li S, Browne EP, Chicoine A, Sutherby D, Noma A; Accelerating Medicines Partnership RA/SLE Network, Nusbaum C, Kelly S, Pernis AB, Ivashkiv LB, Goodman SM, Robinson WH, Utz PJ, Lederer JA, Gravallese EM, Boyce BF, Hacohen N, Pitzalis C, Gregersen PK, Firestein GS, Raychaudhuri S, Moreland LW, Holers VM, Bykerk VP, Filer A, Boyle DL, Brenner MB, Anolik JH.

Arthritis Res Ther. 2018 Jul 11;20(1):139. doi: 10.1186/s13075-018-1631-y.

2.

New headaches with normal inflammatory markers: an early atypical presentation of giant cell arteritis.

Singh R, Sahbudin I, Filer A.

BMJ Case Rep. 2018 Jun 27;2018. pii: bcr-2017-223240. doi: 10.1136/bcr-2017-223240.

3.

Initial validation and results of the Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: a EULAR project.

van Beers-Tas MH, Ter Wee MM, van Tuyl LH, Maat B, Hoogland W, Hensvold AH, Catrina AI, Mosor E, Stamm TA, Finckh A, Courvoisier DS, Filer A, Sahbudin I, Stack RJ, Raza K, van Schaardenburg D.

RMD Open. 2018 May 21;4(1):e000641. doi: 10.1136/rmdopen-2017-000641. eCollection 2018.

4.

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis.

Karouzakis E, Raza K, Kolling C, Buckley CD, Gay S, Filer A, Ospelt C.

Sci Rep. 2018 May 9;8(1):7370. doi: 10.1038/s41598-018-24240-2.

5.

Multispectral, non-contact diffuse optical tomography of healthy human finger joints.

Lighter D, Hughes J, Styles I, Filer A, Dehghani H.

Biomed Opt Express. 2018 Mar 2;9(4):1445-1460. doi: 10.1364/BOE.9.001445. eCollection 2018 Apr 1.

6.

The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development.

Sahbudin I, Pickup L, Nightingale P, Allen G, Cader Z, Singh R, de Pablo P, Buckley CD, Raza K, Filer A.

Rheumatology (Oxford). 2018 Apr 3. doi: 10.1093/rheumatology/key025. [Epub ahead of print]

7.

Dysbiotic Subgingival Microbial Communities in Periodontally Healthy Patients With Rheumatoid Arthritis.

Lopez-Oliva I, Paropkari AD, Saraswat S, Serban S, Yonel Z, Sharma P, de Pablo P, Raza K, Filer A, Chapple I, Dietrich T, Grant MM, Kumar PS.

Arthritis Rheumatol. 2018 Jul;70(7):1008-1013. doi: 10.1002/art.40485. Epub 2018 May 21.

PMID:
29513935
8.

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB.

Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y.

9.

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR.

Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3.

PMID:
29439295
10.

A Multicenter Retrospective Analysis Evaluating Performance of Synovial Biopsy Techniques in Patients With Inflammatory Arthritis: Arthroscopic Versus Ultrasound-Guided Versus Blind Needle Biopsy.

Humby F, Romão VC, Manzo A, Filer A, Bugatti S, Vieira-Sousa E, Kelly S, Wechalekar M, Ahmed M, Rocher V, Hands R, Montecucco C, Fonseca J, Pitzalis C.

Arthritis Rheumatol. 2018 May;70(5):702-710. doi: 10.1002/art.40433. Epub 2018 Apr 2.

PMID:
29409140
11.

Corrigendum: Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Goff BL, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Tas SW, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Dec 19;14(1):60. doi: 10.1038/nrrheum.2017.206.

PMID:
29255214
12.

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint.

Jeffery LE, Henley P, Marium N, Filer A, Sansom DM, Hewison M, Raza K.

J Autoimmun. 2018 Mar;88:50-60. doi: 10.1016/j.jaut.2017.10.001. Epub 2017 Oct 21.

13.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Sep 22;13(10):630. doi: 10.1038/nrrheum.2017.161.

PMID:
28935945
14.

Identification of a transitional fibroblast function in very early rheumatoid arthritis.

Filer A, Ward LSC, Kemble S, Davies CS, Munir H, Rogers R, Raza K, Buckley CD, Nash GB, McGettrick HM.

Ann Rheum Dis. 2017 Dec;76(12):2105-2112. doi: 10.1136/annrheumdis-2017-211286. Epub 2017 Aug 28.

15.

Antibodies against collagen type II are not a general marker of acute arthritis onset.

Manivel VA, Woude DV, Toes R, Filer A, Raza K, Rönnelid J.

Ann Rheum Dis. 2018 Jun;77(6):954-956. doi: 10.1136/annrheumdis-2017-211974. Epub 2017 Aug 24. No abstract available.

PMID:
28839108
16.

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.

Choi IY, Karpus ON, Turner JD, Hardie D, Marshall JL, de Hair MJH, Maijer KI, Tak PP, Raza K, Hamann J, Buckley CD, Gerlag DM, Filer A.

PLoS One. 2017 Aug 9;12(8):e0182751. doi: 10.1371/journal.pone.0182751. eCollection 2017.

17.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ, Tas SW.

Nat Rev Rheumatol. 2017 Aug;13(8):463-475. doi: 10.1038/nrrheum.2017.115. Epub 2017 Jul 13. Review. Erratum in: Nat Rev Rheumatol. 2017 Sep 22;13(10 ):630. Nat Rev Rheumatol. 2017 Dec 19;14 (1):60.

PMID:
28701760
18.

Immunoglobulin characteristics and RNAseq data of FcRL4+ B cells sorted from synovial fluid and tissue of patients with rheumatoid arthritis.

Amara K, Clay E, Yeo L, Ramsköld D, Spengler J, Sippl N, Cameron J, Israelsson L, Titcombe PJ, Grönwall C, Sahbudin I, Filer A, Raza K, Malmström V, Scheel-Toellner D.

Data Brief. 2017 Jun 7;13:356-370. doi: 10.1016/j.dib.2017.06.009. eCollection 2017 Aug.

19.

Detection and characterisation of bone destruction in murine rheumatoid arthritis using statistical shape models.

Brown JM, Ross E, Desanti G, Saghir A, Clark A, Buckley C, Filer A, Naylor A, Claridge E.

Med Image Anal. 2017 Aug;40:30-43. doi: 10.1016/j.media.2017.05.006. Epub 2017 May 23.

PMID:
28595091
20.

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis.

Ntougkos E, Chouvardas P, Roumelioti F, Ospelt C, Frank-Bertoncelj M, Filer A, Buckley CD, Gay S, Nikolaou C, Kollias G.

Arthritis Rheumatol. 2017 Aug;69(8):1588-1600. doi: 10.1002/art.40128. Epub 2017 Jul 5.

PMID:
28409894
21.

B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis.

Amara K, Clay E, Yeo L, Ramsköld D, Spengler J, Sippl N, Cameron JA, Israelsson L, Titcombe PJ, Grönwall C, Sahbudin I, Filer A, Raza K, Malmström V, Scheel-Toellner D.

J Autoimmun. 2017 Jul;81:34-43. doi: 10.1016/j.jaut.2017.03.004. Epub 2017 Mar 24.

22.

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.

Frank-Bertoncelj M, Trenkmann M, Klein K, Karouzakis E, Rehrauer H, Bratus A, Kolling C, Armaka M, Filer A, Michel BA, Gay RE, Buckley CD, Kollias G, Gay S, Ospelt C.

Nat Commun. 2017 Mar 23;8:14852. doi: 10.1038/ncomms14852.

23.

Plasma Levels of Eicosapentaenoic Acid Are Associated with Anti-TNF Responsiveness in Rheumatoid Arthritis and Inhibit the Etanercept-driven Rise in Th17 Cell Differentiation in Vitro.

Jeffery L, Fisk HL, Calder PC, Filer A, Raza K, Buckley CD, McInnes I, Taylor PC, Fisher BA.

J Rheumatol. 2017 Jun;44(6):748-756. doi: 10.3899/jrheum.161068. Epub 2017 Feb 15.

PMID:
28202745
24.

Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts.

Crowley T, O'Neil JD, Adams H, Thomas AM, Filer A, Buckley CD, Clark AR.

Arthritis Res Ther. 2017 Feb 10;19(1):35. doi: 10.1186/s13075-017-1248-6.

25.

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.

Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB.

Nature. 2017 Feb 1;542(7639):110-114. doi: 10.1038/nature20810.

26.

The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives.

Terslev L, Iagnocco A, Bruyn GAW, Naredo E, Vojinovic J, Collado P, Damjanov N, Filer A, Filippou G, Finzel S, Gandjbakhch F, Ikeda K, Keen HI, Kortekaas MC, Magni-Manzoni S, Ohrndorf S, Pineda C, Ravagnani V, Richards B, Sahbudin I, Schmidt WA, Siddle HJ, Stoenoiu MS, Szkudlarek M, Tzaribachev N, D'Agostino MA; OMERACT Ultrasound Group.

J Rheumatol. 2017 Nov;44(11):1740-1743. doi: 10.3899/jrheum.161240. Epub 2017 Feb 1.

PMID:
28148700
27.

Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research.

Pollock J, Raza K, Pratt AG, Hanson H, Siebert S, Filer A, Isaacs JD, Buckley CD, McInnes IB, Falahee M.

Musculoskeletal Care. 2017 Dec;15(4):395-399. doi: 10.1002/msc.1171. Epub 2016 Dec 16. No abstract available.

28.

Detection of antibodies to citrullinated tenascin-C in patients with early synovitis is associated with the development of rheumatoid arthritis.

Raza K, Schwenzer A, Juarez M, Venables P, Filer A, Buckley CD, Midwood KS.

RMD Open. 2016 Dec 1;2(2):e000318. eCollection 2016. No abstract available.

29.
30.

Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage.

Croft AP, Naylor AJ, Marshall JL, Hardie DL, Zimmermann B, Turner J, Desanti G, Adams H, Yemm AI, Müller-Ladner U, Dayer JM, Neumann E, Filer A, Buckley CD.

Arthritis Res Ther. 2016 Nov 18;18(1):270.

31.

11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.

Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, Buckley CD, Lavery GG, Cooper MS, Raza K.

J Pathol. 2016 Dec;240(4):472-483. doi: 10.1002/path.4806. Epub 2016 Oct 18.

32.

Decrease in articular hypoxia and synovial blood flow at early time points following infliximab and etanercept treatment in rheumatoid arthritis.

Fisher BA, Donatien P, Filer A, Winlove CP, McInnes IB, Buckley CD, Taylor PC.

Clin Exp Rheumatol. 2016 Nov-Dec;34(6):1072-1076. Epub 2016 Sep 8.

PMID:
27749236
33.

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.

Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR.

Ann Rheum Dis. 2017 Mar;76(3):612-619. doi: 10.1136/annrheumdis-2016-209424. Epub 2016 Sep 5.

34.

Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma.

McNee G, Eales KL, Wei W, Williams DS, Barkhuizen A, Bartlett DB, Essex S, Anandram S, Filer A, Moss PA, Pratt G, Basu S, Davies CC, Tennant DA.

Leukemia. 2017 Feb;31(2):373-381. doi: 10.1038/leu.2016.187. Epub 2016 Jul 11.

35.

Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines.

Fursov N, Lu J, Healy C, Wu SJ, Lacy E, Filer A, Li Y, Liu C, Lamb R, Jones B, Reddy R, Petley T, Duffy K.

Mol Immunol. 2016 Jul;75:178-87. doi: 10.1016/j.molimm.2016.05.019. Epub 2016 Jun 22.

PMID:
27294560
36.

Nocturnal seizure and simultaneous bilateral shoulder fracture-dislocation.

Sahbudin I, Filer A.

BMJ Case Rep. 2016 Feb 2;2016. pii: bcr2015213489. doi: 10.1136/bcr-2015-213489.

37.

DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system.

Juarez M, McGettrick HM, Scheel-Toellner D, Yeo L, Spengler J, de Paz B, Hardy R, Cooper M, Raza K, Buckley CD, Filer A.

Arthritis Res Ther. 2016 Jan 19;18:14. doi: 10.1186/s13075-016-0915-3.

38.

Observing real-time images during ultrasound-guided procedures improves patients' experience.

Sahbudin I, Bell J, Kumar K, Raza K, Filer A.

Rheumatology (Oxford). 2016 Mar;55(3):585-6. doi: 10.1093/rheumatology/kev368. Epub 2015 Oct 22. No abstract available.

39.

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid.

Spengler J, Lugonja B, Ytterberg AJ, Zubarev RA, Creese AJ, Pearson MJ, Grant MM, Milward M, Lundberg K, Buckley CD, Filer A, Raza K, Cooper PR, Chapple IL, Scheel-Toellner D.

Arthritis Rheumatol. 2015 Dec;67(12):3135-45. doi: 10.1002/art.39313.

40.

Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis.

Juarez M, Bang H, Hammar F, Reimer U, Dyke B, Sahbudin I, Buckley CD, Fisher B, Filer A, Raza K.

Ann Rheum Dis. 2016 Jun;75(6):1099-107. doi: 10.1136/annrheumdis-2014-206785. Epub 2015 Jul 9.

41.

Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.

Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D'Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C.

J Rheumatol. 2016 Jan;43(1):208-13. doi: 10.3899/jrheum.141199. Epub 2015 Jun 1. Review.

PMID:
26034155
42.

Ultrasound-guided synovial biopsy: a systematic review according to the OMERACT filter and recommendations for minimal reporting standards in clinical studies.

Lazarou I, D'Agostino MA, Naredo E, Humby F, Filer A, Kelly SG.

Rheumatology (Oxford). 2015 Oct;54(10):1867-75. doi: 10.1093/rheumatology/kev128. Epub 2015 May 28. Review.

PMID:
26022188
43.

Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis.

Nanus DE, Filer AD, Yeo L, Scheel-Toellner D, Hardy R, Lavery GG, Stewart PM, Buckley CD, Tomlinson JW, Cooper MS, Raza K.

Arthritis Res Ther. 2015 May 14;17:121. doi: 10.1186/s13075-015-0633-2.

44.

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.

Reynolds G, Gibbon JR, Pratt AG, Wood MJ, Coady D, Raftery G, Lorenzi AR, Gray A, Filer A, Buckley CD, Haniffa MA, Isaacs JD, Hilkens CM.

Ann Rheum Dis. 2016 May;75(5):899-907. doi: 10.1136/annrheumdis-2014-206578. Epub 2015 Apr 28.

45.

Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.

Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LSK, Buckley CD, Nash GB, Narendran P, Rainger GE.

Nat Med. 2015 May;21(5):467-475. doi: 10.1038/nm.3842. Epub 2015 Apr 20.

46.

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis.

Yeo L, Adlard N, Biehl M, Juarez M, Smallie T, Snow M, Buckley CD, Raza K, Filer A, Scheel-Toellner D.

Ann Rheum Dis. 2016 Apr;75(4):763-71. doi: 10.1136/annrheumdis-2014-206921. Epub 2015 Apr 9.

47.

Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways.

Filer A, Antczak P, Parsonage GN, Legault HM, O'Toole M, Pearson MJ, Thomas AM, Scheel-Toellner D, Raza K, Buckley CD, Falciani F.

PLoS One. 2015 Mar 25;10(3):e0120917. doi: 10.1371/journal.pone.0120917. eCollection 2015.

48.

Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health.

Ahmed U, Anwar A, Savage RS, Costa ML, Mackay N, Filer A, Raza K, Watts RA, Winyard PG, Tarr J, Haigh RC, Thornalley PJ, Rabbani N.

Sci Rep. 2015 Mar 19;5:9259. doi: 10.1038/srep09259.

49.

The OMERACT Ultrasound Working Group 10 Years On: Update at OMERACT 12.

Bruyn GA, Naredo E, Iagnocco A, Balint PV, Backhaus M, Gandjbakhch F, Gutierrez M, Filer A, Finzel S, Ikeda K, Kaeley GS, Manzoni SM, Ohrndorf S, Pineda C, Richards B, Roth J, Schmidt WA, Terslev L, D'Agostino MA; OMERACT Ultrasound Task Force.

J Rheumatol. 2015 Nov;42(11):2172-6. doi: 10.3899/jrheum.141462. Epub 2015 Mar 15. Review.

50.

The therapeutic window of opportunity in rheumatoid arthritis: does it ever close?

Raza K, Filer A.

Ann Rheum Dis. 2015 May;74(5):793-4. doi: 10.1136/annrheumdis-2014-206993. Epub 2015 Mar 10. No abstract available.

PMID:
25757869

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