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Items: 19

1.

Use of whole genome sequencing in surveillance for antimicrobial-resistant Shigella sonnei infections acquired from domestic and international sources.

Abelman RL, M'ikanatha NM, Figler HM, Dudley EG.

Microb Genom. 2019 May;5(5). doi: 10.1099/mgen.0.000270. Epub 2019 May 17.

2.

Non-pathogenic Escherichia coli Enhance Stx2a Production of E. coli O157:H7 Through Both bamA-Dependent and Independent Mechanisms.

Xiaoli L, Figler HM, Goswami Banerjee K, Hayes CS, Dudley EG.

Front Microbiol. 2018 Jun 15;9:1325. doi: 10.3389/fmicb.2018.01325. eCollection 2018.

3.

Whole-Genome Sequence of Escherichia coli Serotype O157:H7 Strain PA20.

Uhlich GA, Paoli GC, Zhang X, Dudley EG, Figler HM, Cottrell BJ, Andreozzi E.

Genome Announc. 2017 Jan 12;5(2). pii: e01460-16. doi: 10.1128/genomeA.01460-16.

4.

The interplay of Escherichia coli O157:H7 and commensal E. coli: the importance of strain-level identification.

Figler HM, Dudley EG.

Expert Rev Gastroenterol Hepatol. 2016;10(4):415-7. doi: 10.1586/17474124.2016.1155449. Epub 2016 Mar 7. Review. No abstract available.

PMID:
26885676
5.

Multivalent site-specific phage modification enhances the binding affinity of receptor ligands.

Beech J, Saleh L, Frentzel J, Figler H, Corrêa IR Jr, Baker B, Ramspacher C, Marshall M, Dasa S, Linden J, Noren CJ, Kelly KA.

Bioconjug Chem. 2015 Mar 18;26(3):529-36. doi: 10.1021/acs.bioconjchem.5b00011. Epub 2015 Mar 4.

6.

The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers.

Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, Marshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M.

Mol Pharmacol. 2014 Feb;85(2):301-9. doi: 10.1124/mol.113.088682. Epub 2013 Nov 11.

7.

Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.

Devine SM, Gregg A, Figler H, McIntosh K, Urmaliya V, Linden J, Pouton CW, White PJ, Bottle SE, Scammells PJ.

Bioorg Med Chem. 2010 May 1;18(9):3078-87. doi: 10.1016/j.bmc.2010.03.047. Epub 2010 Mar 27.

PMID:
20385496
8.

3- and 6-Substituted 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridines as A1 adenosine receptor allosteric modulators and antagonists.

Aurelio L, Valant C, Figler H, Flynn BL, Linden J, Sexton PM, Christopoulos A, Scammells PJ.

Bioorg Med Chem. 2009 Oct 15;17(20):7353-61. doi: 10.1016/j.bmc.2009.08.024. Epub 2009 Aug 20.

9.

2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists.

Ferguson GN, Valant C, Horne J, Figler H, Flynn BL, Linden J, Chalmers DK, Sexton PM, Christopoulos A, Scammells PJ.

J Med Chem. 2008 Oct 9;51(19):6165-72. doi: 10.1021/jm800557d. Epub 2008 Sep 5.

10.

Blockade of adenosine A2B receptors ameliorates murine colitis.

Kolachala V, Ruble B, Vijay-Kumar M, Wang L, Mwangi S, Figler H, Figler R, Srinivasan S, Gewirtz A, Linden J, Merlin D, Sitaraman S.

Br J Pharmacol. 2008 Sep;155(1):127-37. doi: 10.1038/bjp.2008.227. Epub 2008 Jun 9.

11.

5-Substituted 2-aminothiophenes as A1 adenosine receptor allosteric enhancers.

Aurelio L, Figler H, Flynn BL, Linden J, Scammells PJ.

Bioorg Med Chem. 2008 Feb 1;16(3):1319-27. Epub 2007 Oct 23.

PMID:
17980606
12.

Dual acting antioxidant A1 adenosine receptor agonists.

Gregg A, Bottle SE, Devine SM, Figler H, Linden J, White P, Pouton CW, Urmaliya V, Scammells PJ.

Bioorg Med Chem Lett. 2007 Oct 1;17(19):5437-41. Epub 2007 Jul 25.

PMID:
17689079
13.

2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers.

Nikolakopoulos G, Figler H, Linden J, Scammells PJ.

Bioorg Med Chem. 2006 Apr 1;14(7):2358-65. Epub 2005 Nov 28.

PMID:
16314104
14.

6-aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency.

Chordia MD, Zigler M, Murphree LJ, Figler H, Macdonald TL, Olsson RA, Linden J.

J Med Chem. 2005 Aug 11;48(16):5131-9.

PMID:
16078833
16.

2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications.

Lütjens H, Zickgraf A, Figler H, Linden J, Olsson RA, Scammells PJ.

J Med Chem. 2003 May 8;46(10):1870-7.

PMID:
12723950
17.

2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors.

Tranberg CE, Zickgraf A, Giunta BN, Luetjens H, Figler H, Murphree LJ, Falke R, Fleischer H, Linden J, Scammells PJ, Olsson RA.

J Med Chem. 2002 Jan 17;45(2):382-9.

PMID:
11784142
18.

Gene dose effect reveals no Gs-coupled A2A adenosine receptor reserve in murine T-lymphocytes: studies of cells from A2A-receptor-gene-deficient mice.

Armstrong JM, Chen JF, Schwarzschild MA, Apasov S, Smith PT, Caldwell C, Chen P, Figler H, Sullivan G, Fink S, Linden J, Sitkovsky M.

Biochem J. 2001 Feb 15;354(Pt 1):123-30.

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