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Items: 1 to 50 of 69

1.

The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.

Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B.

Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099.

2.

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.

de Bock CE, Down M, Baidya K, Sweron B, Boyd AW, Fiers M, Burns GF, Molloy TJ, Lock RB, Soulier J, Taghon T, Van Vlierberghe P, Cools J, Holst J, Thorne RF.

Haematologica. 2019 May;104(5):e204-e207. doi: 10.3324/haematol.2018.198424. Epub 2018 Dec 4. No abstract available.

3.

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.

Claes C, Van Den Daele J, Boon R, Schouteden S, Colombo A, Monasor LS, Fiers M, Ordovás L, Nami F, Bohrmann B, Tahirovic S, De Strooper B, Verfaillie CM.

Alzheimers Dement. 2019 Mar;15(3):453-464. doi: 10.1016/j.jalz.2018.09.006. Epub 2018 Nov 12.

4.

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology.

Sierksma A, Lu A, Salta E, Vanden Eynden E, Callaerts-Vegh Z, D'Hooge R, Blum D, Buée L, Fiers M, De Strooper B.

Mol Neurodegener. 2018 Oct 12;13(1):54. doi: 10.1186/s13024-018-0285-1.

5.

A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain.

Davie K, Janssens J, Koldere D, De Waegeneer M, Pech U, Kreft Ł, Aibar S, Makhzami S, Christiaens V, Bravo González-Blas C, Poovathingal S, Hulselmans G, Spanier KI, Moerman T, Vanspauwen B, Geurs S, Voet T, Lammertyn J, Thienpont B, Liu S, Konstantinides N, Fiers M, Verstreken P, Aerts S.

Cell. 2018 Aug 9;174(4):982-998.e20. doi: 10.1016/j.cell.2018.05.057. Epub 2018 Jun 18.

6.

A Temporal Transcriptional Switch Governs Stem Cell Division, Neuronal Numbers, and Maintenance of Differentiation.

Mora N, Oliva C, Fiers M, Ejsmont R, Soldano A, Zhang TT, Yan J, Claeys A, De Geest N, Hassan BA.

Dev Cell. 2018 Apr 9;45(1):53-66.e5. doi: 10.1016/j.devcel.2018.02.023. Epub 2018 Mar 22.

7.

Mapping gene regulatory networks from single-cell omics data.

Fiers MWEJ, Minnoye L, Aibar S, Bravo González-Blas C, Kalender Atak Z, Aerts S.

Brief Funct Genomics. 2018 Jul 1;17(4):246-254. doi: 10.1093/bfgp/elx046.

8.

The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells.

Zalfa F, Panasiti V, Carotti S, Zingariello M, Perrone G, Sancillo L, Pacini L, Luciani F, Roberti V, D'Amico S, Coppola R, Abate SO, Rana RA, De Luca A, Fiers M, Melocchi V, Bianchi F, Farace MG, Achsel T, Marine JC, Morini S, Bagni C.

Cell Death Dis. 2017 Nov 16;8(11):e3169. doi: 10.1038/cddis.2017.521.

9.

A plant-based chemical genomics screen for the identification of flowering inducers.

Fiers M, Hoogenboom J, Brunazzi A, Wennekes T, Angenent GC, Immink RGH.

Plant Methods. 2017 Oct 3;13:78. doi: 10.1186/s13007-017-0230-2. eCollection 2017.

10.

An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody.

Batiuk MY, de Vin F, Duqué SI, Li C, Saito T, Saido T, Fiers M, Belgard TG, Holt MG.

J Biol Chem. 2017 May 26;292(21):8874-8891. doi: 10.1074/jbc.M116.765313. Epub 2017 Apr 3.

11.

Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.

Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, Hardy J, Leroy K, Brion JP, Vanderhaeghen P, De Strooper B.

Neuron. 2017 Mar 8;93(5):1066-1081.e8. doi: 10.1016/j.neuron.2017.02.001. Epub 2017 Feb 23.

12.

Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.

Verfaillie A, Svetlichnyy D, Imrichova H, Davie K, Fiers M, Kalender Atak Z, Hulselmans G, Christiaens V, Aerts S.

Genome Res. 2016 Jul;26(7):882-95. doi: 10.1101/gr.204149.116. Epub 2016 May 18.

13.

Cross-Talk Between Sporophyte and Gametophyte Generations Is Promoted by CHD3 Chromatin Remodelers in Arabidopsis thaliana.

Carter B, Henderson JT, Svedin E, Fiers M, McCarthy K, Smith A, Guo C, Bishop B, Zhang H, Riksen T, Shockley A, Dilkes BP, Boutilier K, Ogas J.

Genetics. 2016 Jun;203(2):817-29. doi: 10.1534/genetics.115.180141. Epub 2016 Apr 13.

14.

Pectobacterium atrosepticum and Pectobacterium carotovorum Harbor Distinct, Independently Acquired Integrative and Conjugative Elements Encoding Coronafacic Acid that Enhance Virulence on Potato Stems.

Panda P, Vanga BR, Lu A, Fiers M, Fineran PC, Butler R, Armstrong K, Ronson CW, Pitman AR.

Front Microbiol. 2016 Mar 31;7:397. doi: 10.3389/fmicb.2016.00397. eCollection 2016.

15.

Draft Genome Sequences of 18 Strains of Pseudomonas Isolated from Kiwifruit Plants in New Zealand and Overseas.

Visnovsky SB, Fiers M, Lu A, Panda P, Taylor R, Pitman AR.

Genome Announc. 2016 Apr 7;4(2). pii: e00061-16. doi: 10.1128/genomeA.00061-16.

16.

Melanoma addiction to the long non-coding RNA SAMMSON.

Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC.

Nature. 2016 Mar 24;531(7595):518-22. doi: 10.1038/nature17161.

PMID:
27008969
17.

Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.

Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo SX, Low DH, Koh CM, Rambow F, Fiers M, Rogiers A, Radaelli E, Al-Haddawi M, Tan SY, Hermans E, Amant F, Yan H, Lakshmanan M, Koumar RC, Lim ST, Derheimer FA, Campbell RM, Bonday Z, Tergaonkar V, Shackleton M, Blattner C, Marine JC, Guccione E.

J Clin Invest. 2016 Jan;126(1):68-84. doi: 10.1172/JCI82534. Epub 2015 Nov 23.

18.

Identification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest Models.

Svetlichnyy D, Imrichova H, Fiers M, Kalender Atak Z, Aerts S.

PLoS Comput Biol. 2015 Nov 12;11(11):e1004590. doi: 10.1371/journal.pcbi.1004590. eCollection 2015 Nov.

19.
20.

FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression.

Fernández E, Li KW, Rajan N, De Rubeis S, Fiers M, Smit AB, Achsel T, Bagni C.

J Neurosci. 2015 Jun 24;35(25):9402-8. doi: 10.1523/JNEUROSCI.4800-14.2015.

21.

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.

Verfaillie A, Imrichova H, Atak ZK, Dewaele M, Rambow F, Hulselmans G, Christiaens V, Svetlichnyy D, Luciani F, Van den Mooter L, Claerhout S, Fiers M, Journe F, Ghanem GE, Herrmann C, Halder G, Marine JC, Aerts S.

Nat Commun. 2015 Apr 9;6:6683. doi: 10.1038/ncomms7683.

22.

Genomes of 'Candidatus Liberibacter solanacearum' Haplotype A from New Zealand and the United States Suggest Significant Genome Plasticity in the Species.

Thompson SM, Johnson CP, Lu AY, Frampton RA, Sullivan KL, Fiers MW, Crowhurst RN, Pitman AR, Scott IA, Wen A, Gudmestad NC, Smith GR.

Phytopathology. 2015 Jul;105(7):863-71. doi: 10.1094/PHYTO-12-14-0363-FI. Epub 2015 Jul 9.

23.

Fast and efficient Drosophila melanogaster gene knock-ins using MiMIC transposons.

Vilain S, Vanhauwaert R, Maes I, Schoovaerts N, Zhou L, Soukup S, da Cunha R, Lauwers E, Fiers M, Verstreken P.

G3 (Bethesda). 2014 Oct 8;4(12):2381-7. doi: 10.1534/g3.114.014803.

24.

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.

Degryse S, de Bock CE, Cox L, Demeyer S, Gielen O, Mentens N, Jacobs K, Geerdens E, Gianfelici V, Hulselmans G, Fiers M, Aerts S, Meijerink JP, Tousseyn T, Cools J.

Blood. 2014 Nov 13;124(20):3092-100. doi: 10.1182/blood-2014-04-566687. Epub 2014 Sep 5.

25.

iRegulon: from a gene list to a gene regulatory network using large motif and track collections.

Janky R, Verfaillie A, Imrichová H, Van de Sande B, Standaert L, Christiaens V, Hulselmans G, Herten K, Naval Sanchez M, Potier D, Svetlichnyy D, Kalender Atak Z, Fiers M, Marine JC, Aerts S.

PLoS Comput Biol. 2014 Jul 24;10(7):e1003731. doi: 10.1371/journal.pcbi.1003731. eCollection 2014 Jul.

26.

Nanophotonic reservoir computing with photonic crystal cavities to generate periodic patterns.

Fiers MA, Van Vaerenbergh T, Wyffels F, Verstraeten D, Schrauwen B, Dambre J, Bienstman P.

IEEE Trans Neural Netw Learn Syst. 2014 Feb;25(2):344-55. doi: 10.1109/TNNLS.2013.2274670.

PMID:
24807033
27.

The draft genome sequence of European pear (Pyrus communis L. 'Bartlett').

Chagné D, Crowhurst RN, Pindo M, Thrimawithana A, Deng C, Ireland H, Fiers M, Dzierzon H, Cestaro A, Fontana P, Bianco L, Lu A, Storey R, Knäbel M, Saeed M, Montanari S, Kim YK, Nicolini D, Larger S, Stefani E, Allan AC, Bowen J, Harvey I, Johnston J, Malnoy M, Troggio M, Perchepied L, Sawyer G, Wiedow C, Won K, Viola R, Hellens RP, Brewer L, Bus VG, Schaffer RJ, Gardiner SE, Velasco R.

PLoS One. 2014 Apr 3;9(4):e92644. doi: 10.1371/journal.pone.0092644. eCollection 2014.

28.

Experimental demonstration of reservoir computing on a silicon photonics chip.

Vandoorne K, Mechet P, Van Vaerenbergh T, Fiers M, Morthier G, Verstraeten D, Schrauwen B, Dambre J, Bienstman P.

Nat Commun. 2014 Mar 24;5:3541. doi: 10.1038/ncomms4541.

PMID:
24662967
29.

Structure and expression of GSL1 and GSL2 genes encoding gibberellin stimulated-like proteins in diploid and highly heterozygous tetraploid potato reveals their highly conserved and essential status.

Meiyalaghan S, Thomson SJ, Fiers MW, Barrell PJ, Latimer JM, Mohan S, Jones EE, Conner AJ, Jacobs JM.

BMC Genomics. 2014 Jan 2;15:2. doi: 10.1186/1471-2164-15-2.

30.

ASSESSING THE FORAGING BEHAVIOR OF AGRIOTES SORDIDUS WIREWORMS IN DUAL-CHOICE OLFACTOMETERS.

Barsics F, Fiers M, Fauconnier ML, Jijakli H, Francis F, Haubruge E, Verheggen FJ.

Commun Agric Appl Biol Sci. 2014;79(2):151-6.

31.

Excitability in optically injected microdisk lasers with phase controlled excitatory and inhibitory response.

Alexander K, Van Vaerenbergh T, Fiers M, Mechet P, Dambre J, Bienstman P.

Opt Express. 2013 Nov 4;21(22):26182-91. doi: 10.1364/OE.21.026182.

PMID:
24216842
32.

Genomic analysis of the Kiwifruit pathogen Pseudomonas syringae pv. actinidiae provides insight into the origins of an emergent plant disease.

McCann HC, Rikkerink EH, Bertels F, Fiers M, Lu A, Rees-George J, Andersen MT, Gleave AP, Haubold B, Wohlers MW, Guttman DS, Wang PW, Straub C, Vanneste JL, Rainey PB, Templeton MD.

PLoS Pathog. 2013;9(7):e1003503. doi: 10.1371/journal.ppat.1003503. Epub 2013 Jul 25. Erratum in: PLoS Pathog. 2013;9(9). doi:10.1371/annotation/af157ddc-200a-4105-b243-3f01251cc677. Vanneste, Joel [corrected to Vanneste, Joel L].

33.

Volatile compound-mediated interactions between barley and pathogenic fungi in the soil.

Fiers M, Lognay G, Fauconnier ML, Jijakli MH.

PLoS One. 2013 Jun 20;8(6):e66805. doi: 10.1371/journal.pone.0066805. Print 2013.

34.

A toolkit for bulk PCR-based marker design from next-generation sequence data: application for development of a framework linkage map in bulb onion (Allium cepa L.).

Baldwin S, Revanna R, Thomson S, Pither-Joyce M, Wright K, Crowhurst R, Fiers M, Chen L, Macknight R, McCallum JA.

BMC Genomics. 2012 Nov 19;13:637. doi: 10.1186/1471-2164-13-637.

35.

Cascadable excitability in microrings.

Van Vaerenbergh T, Fiers M, Mechet P, Spuesens T, Kumar R, Morthier G, Schrauwen B, Dambre J, Bienstman P.

Opt Express. 2012 Aug 27;20(18):20292-308. doi: 10.1364/OE.20.020292.

PMID:
23037081
36.

Effect of a fungal infection on the profile of volatile organic compounds emitted by plant roots.

Fiers M, Lognay G, Wathelet JP, Fauconnier ML, Jijakli MH.

Commun Agric Appl Biol Sci. 2012;77(3):125-8.

PMID:
23878966
37.

Genome sequence and analysis of the tuber crop potato.

Potato Genome Sequencing Consortium, Xu X, Pan S, Cheng S, Zhang B, Mu D, Ni P, Zhang G, Yang S, Li R, Wang J, Orjeda G, Guzman F, Torres M, Lozano R, Ponce O, Martinez D, De la Cruz G, Chakrabarti SK, Patil VU, Skryabin KG, Kuznetsov BB, Ravin NV, Kolganova TV, Beletsky AV, Mardanov AV, Di Genova A, Bolser DM, Martin DM, Li G, Yang Y, Kuang H, Hu Q, Xiong X, Bishop GJ, Sagredo B, Mejía N, Zagorski W, Gromadka R, Gawor J, Szczesny P, Huang S, Zhang Z, Liang C, He J, Li Y, He Y, Xu J, Zhang Y, Xie B, Du Y, Qu D, Bonierbale M, Ghislain M, Herrera Mdel R, Giuliano G, Pietrella M, Perrotta G, Facella P, O'Brien K, Feingold SE, Barreiro LE, Massa GA, Diambra L, Whitty BR, Vaillancourt B, Lin H, Massa AN, Geoffroy M, Lundback S, DellaPenna D, Buell CR, Sharma SK, Marshall DF, Waugh R, Bryan GJ, Destefanis M, Nagy I, Milbourne D, Thomson SJ, Fiers M, Jacobs JM, Nielsen KL, Sønderkær M, Iovene M, Torres GA, Jiang J, Veilleux RE, Bachem CW, de Boer J, Borm T, Kloosterman B, van Eck H, Datema E, Hekkert Bt, Goverse A, van Ham RC, Visser RG.

Nature. 2011 Jul 10;475(7355):189-95. doi: 10.1038/nature10158.

PMID:
21743474
38.

Genetic diversity of Rhizoctonia solani associated with potato tubers in France.

Fiers M, Edel-Hermann V, Héraud C, Gautheron N, Chatot C, Le Hingrat Y, Bouchek-Mechiche K, Steinberg C.

Mycologia. 2011 Nov-Dec;103(6):1230-44. doi: 10.3852/10-231. Epub 2011 Jun 3.

PMID:
21642342
39.

Genomics of biotrophic, plant-infecting plasmodiophorids using in vitro dual cultures.

Bulman S, Candy JM, Fiers M, Lister R, Conner AJ, Eady CC.

Protist. 2011 Jul;162(3):449-61. doi: 10.1016/j.protis.2010.09.004. Epub 2010 Dec 23.

PMID:
21183405
40.

Evolution of Rhizaria: new insights from phylogenomic analysis of uncultivated protists.

Burki F, Kudryavtsev A, Matz MV, Aglyamova GV, Bulman S, Fiers M, Keeling PJ, Pawlowski J.

BMC Evol Biol. 2010 Dec 2;10:377. doi: 10.1186/1471-2148-10-377.

41.

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

van Dijk AD, Morabito G, Fiers M, van Ham RC, Angenent GC, Immink RG.

PLoS Comput Biol. 2010 Nov 24;6(11):e1001017. doi: 10.1371/journal.pcbi.1001017.

42.

New aspects of CLAVATA2, a versatile gene in the regulation of Arabidopsis development.

Wang G, Zhang Z, Angenent GC, Fiers M.

J Plant Physiol. 2011 Mar 1;168(4):403-7. doi: 10.1016/j.jplph.2010.08.015. Epub 2010 Oct 18.

PMID:
20961653
43.

Identification of Mendel's white flower character.

Hellens RP, Moreau C, Lin-Wang K, Schwinn KE, Thomson SJ, Fiers MW, Frew TJ, Murray SR, Hofer JM, Jacobs JM, Davies KM, Allan AC, Bendahmane A, Coyne CJ, Timmerman-Vaughan GM, Ellis TH.

PLoS One. 2010 Oct 11;5(10):e13230. doi: 10.1371/journal.pone.0013230.

44.

Arabidopsis thaliana transcription factors bZIP19 and bZIP23 regulate the adaptation to zinc deficiency.

Assunção AG, Herrero E, Lin YF, Huettel B, Talukdar S, Smaczniak C, Immink RG, van Eldik M, Fiers M, Schat H, Aarts MG.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10296-301. doi: 10.1073/pnas.1004788107. Epub 2010 May 17.

45.

Receptor-like proteins: searching for functions.

Wang G, Fiers M.

Plant Signal Behav. 2010 May;5(5):540-2. doi: 10.4161/psb.11030. Epub 2010 Feb 8.

PMID:
20139740
46.

CLE peptide signaling during plant development.

Wang G, Fiers M.

Protoplasma. 2010 Apr;240(1-4):33-43. doi: 10.1007/s00709-009-0095-y. Epub 2009 Dec 17. Review.

47.

Functional analyses of the CLAVATA2-like proteins and their domains that contribute to CLAVATA2 specificity.

Wang G, Long Y, Thomma BP, de Wit PJ, Angenent GC, Fiers M.

Plant Physiol. 2010 Jan;152(1):320-31. doi: 10.1104/pp.109.148197. Epub 2009 Nov 6.

48.

In silico miRNA prediction in metazoan genomes: balancing between sensitivity and specificity.

van der Burgt A, Fiers MW, Nap JP, van Ham RC.

BMC Genomics. 2009 Apr 30;10:204. doi: 10.1186/1471-2164-10-204.

49.

High-throughput bioinformatics with the Cyrille2 pipeline system.

Fiers MW, van der Burgt A, Datema E, de Groot JC, van Ham RC.

BMC Bioinformatics. 2008 Feb 12;9:96. doi: 10.1186/1471-2105-9-96.

50.

Post alignment clustering procedure for comparative quantitative proteomics LC-MS data.

de Groot JC, Fiers MW, van Ham RC, America AH.

Proteomics. 2008 Jan;8(1):32-6.

PMID:
18095361

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