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Items: 1 to 50 of 52

1.

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.

Hahn A, Kny M, Pablo-Tortola C, Todiras M, Willenbrock M, Schmidt S, Schmoeckel K, Jorde I, Nowak M, Jarosch E, Sommer T, Bröker BM, Felix SB, Scheidereit C, Weber-Carstens S, Butter C, Luft FC, Fielitz J.

J Cachexia Sarcopenia Muscle. 2019 Aug 23. doi: 10.1002/jcsm.12491. [Epub ahead of print]

2.

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

Nowak M, Suenkel B, Porras P, Migotti R, Schmidt F, Kny M, Zhu X, Wanker EE, Dittmar G, Fielitz J, Sommer T.

J Cell Sci. 2019 Sep 6;132(17). pii: jcs233395. doi: 10.1242/jcs.233395.

PMID:
31391242
3.

Ninjurin1 regulates striated muscle growth and differentiation.

Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J.

PLoS One. 2019 May 15;14(5):e0216987. doi: 10.1371/journal.pone.0216987. eCollection 2019.

4.

Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.

Wollersheim T, Grunow JJ, Carbon NM, Haas K, Malleike J, Ramme SF, Schneider J, Spies CD, Märdian S, Mai K, Spuler S, Fielitz J, Weber-Carstens S.

J Cachexia Sarcopenia Muscle. 2019 Aug;10(4):734-747. doi: 10.1002/jcsm.12428. Epub 2019 Apr 23.

5.

Sugars make the difference - Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy.

Reinke Y, Könemann S, Chamling B, Gross S, Weitmann K, Hoffmann W, Klingel K, Nauck M, Fielitz J, Dörr M, Felix SB.

Int J Cardiol. 2019 Oct 1;292:156-159. doi: 10.1016/j.ijcard.2019.04.025. Epub 2019 Apr 9.

PMID:
31005416
6.

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.

Gong M, Yu Y, Liang L, Vuralli D, Froehler S, Kuehnen P, Du Bois P, Zhang J, Cao A, Liu Y, Hussain K, Fielitz J, Jia S, Chen W, Raile K.

Mol Genet Genomic Med. 2019 May;7(5):e602. doi: 10.1002/mgg3.602. Epub 2019 Apr 9.

7.

Angiotensin-(1-7) Receptor Mas in Hemodynamic and Thermoregulatory Dysfunction After High-Level Spinal Cord Injury in Mice: A Pilot Study.

Järve A, Todiras M, Kny M, Fischer FI, Kraemer JF, Wessel N, Plehm R, Fielitz J, Alenina N, Bader M.

Front Physiol. 2019 Jan 11;9:1930. doi: 10.3389/fphys.2018.01930. eCollection 2018.

8.

Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.

Bartolomaeus H, Balogh A, Yakoub M, Homann S, Markó L, Höges S, Tsvetkov D, Krannich A, Wundersitz S, Avery EG, Haase N, Kräker K, Hering L, Maase M, Kusche-Vihrog K, Grandoch M, Fielitz J, Kempa S, Gollasch M, Zhumadilov Z, Kozhakhmetov S, Kushugulova A, Eckardt KU, Dechend R, Rump LC, Forslund SK, Müller DN, Stegbauer J, Wilck N.

Circulation. 2019 Mar 12;139(11):1407-1421. doi: 10.1161/CIRCULATIONAHA.118.036652.

9.

Author Correction: Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.

Pose-Utrilla J, García-Guerra L, Del Puerto A, Martín A, Jurado-Arjona J, De León-Reyes NS, Gamir-Morralla A, Sebastián-Serrano Á, García-Gallo M, Kremer L, Fielitz J, Ireson C, Pérez-Álvarez MJ, Ferrer I, Hernández F, Ávila J, Lasa M, Campanero MR, Iglesias T.

Nat Commun. 2018 Jan 30;9(1):473. doi: 10.1038/s41467-018-03022-4.

10.

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.

Pose-Utrilla J, García-Guerra L, Del Puerto A, Martín A, Jurado-Arjona J, De León-Reyes NS, Gamir-Morralla A, Sebastián-Serrano Á, García-Gallo M, Kremer L, Fielitz J, Ireson C, Pérez-Álvarez MJ, Ferrer I, Hernández F, Ávila J, Lasa M, Campanero MR, Iglesias T.

Nat Commun. 2017 Dec 22;8(1):2275. doi: 10.1038/s41467-017-02322-5. Erratum in: Nat Commun. 2018 Jan 30;9(1):473.

11.

Deletion of Protein Kinase D1 in Pancreatic β-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice.

Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V.

Diabetes. 2018 Jan;67(1):71-77. doi: 10.2337/db17-0982. Epub 2017 Oct 16.

12.

Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy.

Huang N, Kny M, Riediger F, Busch K, Schmidt S, Luft FC, Slevogt H, Fielitz J.

Intensive Care Med Exp. 2017 Dec;5(1):3. doi: 10.1186/s40635-016-0115-0. Epub 2017 Jan 17.

13.

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I.

Fernandez AM, Hernandez-Garzón E, Perez-Domper P, Perez-Alvarez A, Mederos S, Matsui T, Santi A, Trueba-Saiz A, García-Guerra L, Pose-Utrilla J, Fielitz J, Olson EN, Fernandez de la Rosa R, Garcia Garcia L, Pozo MA, Iglesias T, Araque A, Soya H, Perea G, Martin ED, Torres Aleman I.

Diabetes. 2017 Jan;66(1):64-74. doi: 10.2337/db16-0861. Epub 2016 Oct 10.

14.

Secreted Frizzled-Related Protein 2 and Inflammation-Induced Skeletal Muscle Atrophy.

Zhu X, Kny M, Schmidt F, Hahn A, Wollersheim T, Kleber C, Weber-Carstens S, Fielitz J.

Crit Care Med. 2017 Feb;45(2):e169-e183. doi: 10.1097/CCM.0000000000002056.

PMID:
27661566
15.

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.

Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, Olson EN, Dittmar G, Sommer T, Fielitz J.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):165-80. doi: 10.1002/jcsm.12057. Epub 2015 Sep 7.

16.

Cancer cachexia-when proteasomal inhibition is not enough.

Fielitz J.

J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):239-45. doi: 10.1002/jcsm.12124. Epub 2016 Jun 13. No abstract available.

17.

Critical illness polyneuropathy in ICU patients is related to reduced motor nerve excitability caused by reduced sodium permeability.

Koch S, Bierbrauer J, Haas K, Wolter S, Grosskreutz J, Luft FC, Spies CD, Fielitz J, Weber-Carstens S.

Intensive Care Med Exp. 2016 Dec;4(1):10. doi: 10.1186/s40635-016-0083-4. Epub 2016 May 20.

18.

Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression.

Du Bois P, Pablo Tortola C, Lodka D, Kny M, Schmidt F, Song K, Schmidt S, Bassel-Duby R, Olson EN, Fielitz J.

Circ Res. 2015 Aug 14;117(5):424-36. doi: 10.1161/CIRCRESAHA.114.305393. Epub 2015 Jul 2.

19.

Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure Progression.

Bogomolovas J, Brohm K, Čelutkienė J, Balčiūnaitė G, Bironaitė D, Bukelskienė V, Daunoravičus D, Witt CC, Fielitz J, Grabauskienė V, Labeit S.

Biomed Res Int. 2015;2015:273936. doi: 10.1155/2015/273936. Epub 2015 Apr 16.

20.

The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy.

Schmidt F, Kny M, Zhu X, Wollersheim T, Persicke K, Langhans C, Lodka D, Kleber C, Weber-Carstens S, Fielitz J.

Crit Care. 2014 Sep 29;18(5):545. doi: 10.1186/s13054-014-0545-6.

21.

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.

Langhans C, Weber-Carstens S, Schmidt F, Hamati J, Kny M, Zhu X, Wollersheim T, Koch S, Krebs M, Schulz H, Lodka D, Saar K, Labeit S, Spies C, Hubner N, Spranger J, Spuler S, Boschmann M, Dittmar G, Butler-Browne G, Mouly V, Fielitz J.

PLoS One. 2014 Mar 20;9(3):e92048. doi: 10.1371/journal.pone.0092048. eCollection 2014.

22.

Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness.

Wollersheim T, Woehlecke J, Krebs M, Hamati J, Lodka D, Luther-Schroeder A, Langhans C, Haas K, Radtke T, Kleber C, Spies C, Labeit S, Schuelke M, Spuler S, Spranger J, Weber-Carstens S, Fielitz J.

Intensive Care Med. 2014 Apr;40(4):528-38. doi: 10.1007/s00134-014-3224-9. Epub 2014 Feb 15.

PMID:
24531339
23.

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction.

Weber-Carstens S, Schneider J, Wollersheim T, Assmann A, Bierbrauer J, Marg A, Al Hasani H, Chadt A, Wenzel K, Koch S, Fielitz J, Kleber C, Faust K, Mai K, Spies CD, Luft FC, Boschmann M, Spranger J, Spuler S.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):387-96. doi: 10.1164/rccm.201209-1649OC. Epub 2012 Dec 13.

PMID:
23239154
24.

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.

Ferdaoussi M, Bergeron V, Zarrouki B, Kolic J, Cantley J, Fielitz J, Olson EN, Prentki M, Biden T, MacDonald PE, Poitout V.

Diabetologia. 2012 Oct;55(10):2682-2692. doi: 10.1007/s00125-012-2650-x. Epub 2012 Jul 22.

25.

Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane.

Bierbrauer J, Koch S, Olbricht C, Hamati J, Lodka D, Schneider J, Luther-Schröder A, Kleber C, Faust K, Wiesener S, Spies CD, Spranger J, Spuler S, Fielitz J, Weber-Carstens S.

Crit Care Med. 2012 Feb;40(2):647-50. doi: 10.1097/CCM.0b013e31823295e6.

PMID:
21963579
26.

Skeletal muscle 11beta-HSD1 controls glucocorticoid-induced proteolysis and expression of E3 ubiquitin ligases atrogin-1 and MuRF-1.

Biedasek K, Andres J, Mai K, Adams S, Spuler S, Fielitz J, Spranger J.

PLoS One. 2011 Jan 31;6(1):e16674. doi: 10.1371/journal.pone.0016674.

27.

Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.

van Rooij E, Fielitz J, Sutherland LB, Thijssen VL, Crijns HJ, Dimaio MJ, Shelton J, De Windt LJ, Hill JA, Olson EN.

Circ Res. 2010 Jan 8;106(1):155-65. doi: 10.1161/CIRCRESAHA.109.207084. Epub 2009 Nov 5.

28.

Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance.

Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R, Olson EN.

Mol Cell Biol. 2008 Jun;28(11):3600-9. doi: 10.1128/MCB.00189-08. Epub 2008 Mar 31.

29.

Requirement of protein kinase D1 for pathological cardiac remodeling.

Fielitz J, Kim MS, Shelton JM, Qi X, Hill JA, Richardson JA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3059-63. doi: 10.1073/pnas.0712265105. Epub 2008 Feb 14.

30.

Up-regulation of PPARgamma in myocardial infarction.

Fliegner D, Westermann D, Riad A, Schubert C, Becher E, Fielitz J, Tschöpe C, Regitz-Zagrosek V.

Eur J Heart Fail. 2008 Jan;10(1):30-8. Epub 2007 Dec 27.

31.

Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.

Fielitz J, Kim MS, Shelton JM, Latif S, Spencer JA, Glass DJ, Richardson JA, Bassel-Duby R, Olson EN.

J Clin Invest. 2007 Sep;117(9):2486-95.

32.

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.

Montgomery RL, Davis CA, Potthoff MJ, Haberland M, Fielitz J, Qi X, Hill JA, Richardson JA, Olson EN.

Genes Dev. 2007 Jul 15;21(14):1790-802.

33.

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction.

Fielitz J, van Rooij E, Spencer JA, Shelton JM, Latif S, van der Nagel R, Bezprozvannaya S, de Windt L, Richardson JA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4377-82. Epub 2007 Mar 2.

34.

Inhibition of prolyl 4-hydroxylase prevents left ventricular remodelling in rats with thoracic aortic banding.

Fielitz J, Philipp S, Herda LR, Schuch E, Pilz B, Schubert C, Günzler V, Willenbrock R, Regitz-Zagrosek V.

Eur J Heart Fail. 2007 Apr;9(4):336-42. Epub 2006 Dec 4.

35.

Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats.

Philipp S, Jürgensen JS, Fielitz J, Bernhardt WM, Weidemann A, Schiche A, Pilz B, Dietz R, Regitz-Zagrosek V, Eckardt KU, Willenbrock R.

Eur J Heart Fail. 2006 Jun;8(4):347-54. Epub 2006 Mar 2.

36.

Cardiac PPARalpha expression in patients with dilated cardiomyopathy.

Schupp M, Kintscher U, Fielitz J, Thomas J, Pregla R, Hetzer R, Unger T, Regitz-Zagrosek V.

Eur J Heart Fail. 2006 May;8(3):290-4. Epub 2005 Nov 22.

37.

Mechanisms of blood pressure variability-induced cardiac hypertrophy and dysfunction in mice with impaired baroreflex.

Martinka P, Fielitz J, Patzak A, Regitz-Zagrosek V, Persson PB, Stauss HM.

Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R767-76. Epub 2004 Nov 24.

38.

Regulation of matrix metalloproteinases and their inhibitors in the left ventricular myocardium of patients with aortic stenosis.

Fielitz J, Leuschner M, Zurbrügg HR, Hannack B, Pregla R, Hetzer R, Regitz-Zagrosek V.

J Mol Med (Berl). 2004 Dec;82(12):809-20. Epub 2004 Nov 19.

PMID:
15558223
39.

Upregulation of myocardial estrogen receptors in human aortic stenosis.

Nordmeyer J, Eder S, Mahmoodzadeh S, Martus P, Fielitz J, Bass J, Bethke N, Zurbrügg HR, Pregla R, Hetzer R, Regitz-Zagrosek V.

Circulation. 2004 Nov 16;110(20):3270-5. Epub 2004 Nov 8.

PMID:
15533858
40.

A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.

Bush E, Fielitz J, Melvin L, Martinez-Arnold M, McKinsey TA, Plichta R, Olson EN.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2870-5. Epub 2004 Feb 19.

41.

Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease.

Buchhorn R, Hulpke-Wette M, Ruschewski W, Ross RD, Fielitz J, Pregla R, Hetzer R, Regitz-Zagrosek V.

Cardiol Young. 2003 Feb;13(1):36-43.

PMID:
12691286
42.

Beta-receptor downregulation in congenital heart disease: a risk factor for complications after surgical repair?

Buchhorn R, Hulpke-Wette M, Ruschewski W, Pregla R, Fielitz J, Hetzer R, Regitz-Zagrosek V.

Ann Thorac Surg. 2002 Feb;73(2):610-3.

PMID:
11845882
43.

Neutral endopeptidase is activated in cardiomyocytes in human aortic valve stenosis and heart failure.

Fielitz J, Dendorfer A, Pregla R, Ehler E, Zurbrügg HR, Bartunek J, Hetzer R, Regitz-Zagrosek V.

Circulation. 2002 Jan 22;105(3):286-9.

PMID:
11804980
44.

Activation of the cardiac renin-angiotensin system and increased myocardial collagen expression in human aortic valve disease.

Fielitz J, Hein S, Mitrovic V, Pregla R, Zurbrügg HR, Warnecke C, Schaper J, Fleck E, Regitz-Zagrosek V.

J Am Coll Cardiol. 2001 Apr;37(5):1443-9.

45.
46.

Angiotensin II directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mRNA expression in the human heart.

Kupfahl C, Pink D, Friedrich K, Zurbrügg HR, Neuss M, Warnecke C, Fielitz J, Graf K, Fleck E, Regitz-Zagrosek V.

Cardiovasc Res. 2000 Jun;46(3):463-75.

PMID:
10912457
48.

Myocardial angiotensin receptors in human hearts.

Regitz-Zagrosek V, Fielitz J, Fleck E.

Basic Res Cardiol. 1998;93 Suppl 2:37-42. Review.

PMID:
9833160
49.

Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure.

Regitz-Zagrosek V, Fielitz J, Dreysse R, Hildebrandt AG, Fleck E.

Cardiovasc Res. 1997 Jul;35(1):99-105.

PMID:
9302352
50.

Decreased expression of ventricular angiotensin receptor type 1 mRNA after human heart transplantation.

Regitz-Zagrosek V, Fielitz J, Hummel M, Hildebrandt AG, Hetzer R, Fleck E.

J Mol Med (Berl). 1996 Dec;74(12):777-82.

PMID:
8974019

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