Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 73

1.

Intravitreal gas injection for the treatment of full-thickness macular holes.

Anderson MF, Magal I, Ells A, Fielden M, Mahsin M, Kherani A, Williams RG.

Can J Ophthalmol. 2019 Jun 29. pii: S0008-4182(18)31220-1. doi: 10.1016/j.jcjo.2019.04.011. [Epub ahead of print] No abstract available.

PMID:
31712036
2.

Pharmacodynamics of romiplostim alone and in combination with pegfilgrastim on acute radiation-induced thrombocytopenia and neutropenia in non-human primates.

Wong K, Chang PY, Fielden M, Downey AM, Bunin D, Bakke J, Gahagen J, Iyer L, Doshi S, Wierzbicki W, Authier S.

Int J Radiat Biol. 2019 Jun 21:1-12. doi: 10.1080/09553002.2019.1625488. [Epub ahead of print]

PMID:
31216213
3.

OUTCOMES OF VITRECTOMY IN TERSON SYNDROME: A Multicenter Canadian Perspective.

Nazarali S, Kherani I, Hurley B, Williams G, Fielden M, Adatia F, Kherani A.

Retina. 2019 May 27. doi: 10.1097/IAE.0000000000002570. [Epub ahead of print]

PMID:
31145391
4.

Romiplostim (Nplate®) as an effective radiation countermeasure to improve survival and platelet recovery in mice.

Bunin DI, Bakke J, Green CE, Javitz HS, Fielden M, Chang PY.

Int J Radiat Biol. 2019 Apr 25:1-10. doi: 10.1080/09553002.2019.1605465. [Epub ahead of print]

PMID:
31021662
5.

Probable Vogt-Koyanagi-Harada disease with granulomatous tattoo-related dermatitis.

Gill I, Ziouzina O, Kalisiak M, Fielden M.

Can J Ophthalmol. 2018 Oct;53(5):e179-e182. doi: 10.1016/j.jcjo.2018.01.012. Epub 2018 Mar 7. No abstract available.

PMID:
30340735
6.

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.

Frye M, Taddei A, Dierkes C, Martinez-Corral I, Fielden M, Ortsäter H, Kazenwadel J, Calado DP, Ostergaard P, Salminen M, He L, Harvey NL, Kiefer F, Mäkinen T.

Nat Commun. 2018 Apr 17;9(1):1511. doi: 10.1038/s41467-018-03959-6.

7.

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic.

Mukherjee SP, Gliga AR, Lazzaretto B, Brandner B, Fielden M, Vogt C, Newman L, Rodrigues AF, Shao W, Fournier PM, Toprak MS, Star A, Kostarelos K, Bhattacharya K, Fadeel B.

Nanoscale. 2018 Jan 18;10(3):1180-1188. doi: 10.1039/c7nr03552g.

PMID:
29271441
8.

Lid splinting eyelid retraction technique: a minimised sterile approach for intravitreal injections.

Munro M, Williams GR, Ells A, Fielden M, Kherani A, Mitchell P, Ruzicki J, Adatia FA.

Br J Ophthalmol. 2018 Sep;102(9):1254-1258. doi: 10.1136/bjophthalmol-2017-311081. Epub 2017 Dec 15.

PMID:
29246893
9.

Modernizing Human Cancer Risk Assessment of Therapeutics.

Fielden MR, Ward LD, Minocherhomji S, Nioi P, Lebrec H, Jacobson-Kram D.

Trends Pharmacol Sci. 2018 Mar;39(3):232-247. doi: 10.1016/j.tips.2017.11.005. Epub 2017 Dec 11. Review.

PMID:
29242029
10.

Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D.

Low JD, Bartberger MD, Chen K, Cheng Y, Fielden MR, Gore V, Hickman D, Liu Q, Allen Sickmier E, Vargas HM, Werner J, White RD, Whittington DA, Wood S, Minatti AE.

Medchemcomm. 2017 Apr 27;8(6):1196-1206. doi: 10.1039/c7md00106a. eCollection 2017 Jun 1.

11.

RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.

Alkasalias T, Alexeyenko A, Hennig K, Danielsson F, Lebbink RJ, Fielden M, Turunen SP, Lehti K, Kashuba V, Madapura HS, Bozoky B, Lundberg E, Balland M, Guvén H, Klein G, Gad AK, Pavlova T.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1413-E1421. doi: 10.1073/pnas.1621161114. Epub 2017 Feb 7.

12.

Lubrication synergy: Mixture of hyaluronan and dipalmitoylphosphatidylcholine (DPPC) vesicles.

Raj A, Wang M, Zander T, Wieland DCF, Liu X, An J, Garamus VM, Willumeit-Römer R, Fielden M, Claesson PM, Dėdinaitė A.

J Colloid Interface Sci. 2017 Feb 15;488:225-233. doi: 10.1016/j.jcis.2016.10.091. Epub 2016 Nov 1.

13.

Hydroxychloroquine-induced retinopathy in a 57-year-old woman.

Ragan A, Fielden M.

CMAJ. 2017 Jan 16;189(2):E69-E72. doi: 10.1503/cmaj.150716. Epub 2016 Jul 11. No abstract available.

14.

Nonclinical Safety Profile of Etelcalcetide, a Novel Peptide Calcimimetic for the Treatment of Secondary Hyperparathyroidism.

Fielden MR, Dean C Jr, Black K, Sawant SG, Subramanian R, Tomlinson JE, Walter S, Zimmermann C, Griggs MW, McKeon ME, Lewis EM, Beevers C, Pyrah I.

Int J Toxicol. 2016 May;35(3):294-308. doi: 10.1177/1091581816633407. Epub 2016 Mar 2.

PMID:
26941242
15.

Wetting hysteresis induced by temperature changes: Supercooled water on hydrophobic surfaces.

Heydari G, Sedighi Moghaddam M, Tuominen M, Fielden M, Haapanen J, Mäkelä JM, Claesson PM.

J Colloid Interface Sci. 2016 Apr 15;468:21-33. doi: 10.1016/j.jcis.2016.01.040. Epub 2016 Jan 21.

PMID:
26821148
16.

Experimental and computational assessment of F-actin influence in regulating cellular stiffness and relaxation behaviour of fibroblasts.

Fallqvist B, Fielden ML, Pettersson T, Nordgren N, Kroon M, Gad AKB.

J Mech Behav Biomed Mater. 2016 Jun;59:168-184. doi: 10.1016/j.jmbbm.2015.11.039. Epub 2015 Dec 18.

PMID:
26766328
17.

Effects of malicious ocular laser exposure in commercial airline pilots.

Palakkamanil MM, Fielden MP.

Can J Ophthalmol. 2015 Dec;50(6):429-32. doi: 10.1016/j.jcjo.2015.09.002.

PMID:
26651301
18.

RETINAL LESION EVOLUTION IN SUSAC SYNDROME.

Brandt AU, Oberwahrenbrock T, Costello F, Fielden M, Gertz K, Kleffner I, Paul F, Bergholz R, Dörr J.

Retina. 2016 Feb;36(2):366-74. doi: 10.1097/IAE.0000000000000700.

PMID:
26200513
19.

Retinal Toxicity Induced by a Novel β-secretase Inhibitor in the Sprague-Dawley Rat.

Fielden MR, Werner J, Jamison JA, Coppi A, Hickman D, Dunn RT 2nd, Trueblood E, Zhou L, Afshari CA, Lightfoot-Dunn R.

Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31.

PMID:
25361751
20.

Treatment of ocular metastasis with anti-VEGF: a literature review and case report.

Augustine H, Munro M, Adatia F, Webster M, Fielden M.

Can J Ophthalmol. 2014 Oct;49(5):458-63. doi: 10.1016/j.jcjo.2014.06.008. Review.

PMID:
25284103
21.

Evaluation of genotoxicity testing of FDA approved large molecule therapeutics.

Sawant SG, Fielden MR, Black KA.

Regul Toxicol Pharmacol. 2014 Oct;70(1):87-97. doi: 10.1016/j.yrtph.2014.06.005. Epub 2014 Jun 13.

PMID:
24932799
22.

Piperazine oxadiazole inhibitors of acetyl-CoA carboxylase.

Bourbeau MP, Siegmund A, Allen JG, Shu H, Fotsch C, Bartberger MD, Kim KW, Komorowski R, Graham M, Busby J, Wang M, Meyer J, Xu Y, Salyers K, Fielden M, Véniant MM, Gu W.

J Med Chem. 2013 Dec 27;56(24):10132-41. doi: 10.1021/jm401601s. Epub 2013 Dec 11.

PMID:
24294923
23.

Authors' response to letter to the editor on "image cytometry protocols".

Garrido R, Zabka TS, Tao J, Fielden MR, Fretland AJ, Albassam M.

J Histochem Cytochem. 2013 Oct;61(10):761-2. doi: 10.1369/0022155413502057. No abstract available.

24.

A case of isolated Susac occlusive retinal vasculitis.

Seamone ME, Fielden M.

J Neuroophthalmol. 2013 Sep;33(3):260-2. doi: 10.1097/WNO.0b013e31828bb64b.

PMID:
23612239
25.

Quantitative histological assessment of xenobiotic-induced liver enzyme induction and pituitary-thyroid axis stimulation in rats using whole-slide automated image analysis.

Garrido R, Zabka TS, Tao J, Fielden M, Fretland A, Albassam M.

J Histochem Cytochem. 2013 May;61(5):362-71. doi: 10.1369/0022155413482926. Epub 2013 Mar 1.

26.

Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat.

Fielden MR, Adai A, Dunn RT 2nd, Olaharski A, Searfoss G, Sina J, Aubrecht J, Boitier E, Nioi P, Auerbach S, Jacobson-Kram D, Raghavan N, Yang Y, Kincaid A, Sherlock J, Chen SJ, Car B; Predictive Safety Testing Consortium, Carcinogenicity Working Group.

Toxicol Sci. 2011 Nov;124(1):54-74. doi: 10.1093/toxsci/kfr202. Epub 2011 Aug 2.

PMID:
21813463
27.

Raf inhibition causes extensive multiple tissue hyperplasia and urinary bladder neoplasia in the rat.

Wisler JA, Afshari C, Fielden M, Zimmermann C, Taylor S, Carnahan J, Vonderfecht S.

Toxicol Pathol. 2011 Aug;39(5):809-22. doi: 10.1177/0192623311410442. Epub 2011 Jun 15.

PMID:
21677315
28.

Characterization of xenobiotic-induced hepatocellular enzyme induction in rats: anticipated thyroid effects and unique pituitary gland findings.

Zabka TS, Fielden MR, Garrido R, Tao J, Fretland AJ, Fretland JL, Albassam MA, Singer T, Kolaja KL.

Toxicol Pathol. 2011 Jun;39(4):664-77. doi: 10.1177/0192623311406934. Epub 2011 May 5.

PMID:
21551028
29.

Ocular perforation by an acupuncture needle.

Fielden M, Hall R, Kherani F, Crichton A, Kherani A.

Can J Ophthalmol. 2011 Feb;46(1):94-5. doi: 10.3129/i10-122. No abstract available.

PMID:
21283171
30.

Acute intraocular inflammation following intravitreal injection of bevacizumab--a large cluster of cases.

Fielden M, Nelson B, Kherani A.

Acta Ophthalmol. 2011 Dec;89(8):e664-5. doi: 10.1111/j.1755-3768.2010.02054.x. Epub 2010 Dec 15. No abstract available.

31.

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.

Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu TM, Goodsaid FM, Pusztai L, Shaughnessy JD Jr, Oberthuer A, Thomas RS, Paules RS, Fielden M, Barlogie B, Chen W, Du P, Fischer M, Furlanello C, Gallas BD, Ge X, Megherbi DB, Symmans WF, Wang MD, Zhang J, Bitter H, Brors B, Bushel PR, Bylesjo M, Chen M, Cheng J, Cheng J, Chou J, Davison TS, Delorenzi M, Deng Y, Devanarayan V, Dix DJ, Dopazo J, Dorff KC, Elloumi F, Fan J, Fan S, Fan X, Fang H, Gonzaludo N, Hess KR, Hong H, Huan J, Irizarry RA, Judson R, Juraeva D, Lababidi S, Lambert CG, Li L, Li Y, Li Z, Lin SM, Liu G, Lobenhofer EK, Luo J, Luo W, McCall MN, Nikolsky Y, Pennello GA, Perkins RG, Philip R, Popovici V, Price ND, Qian F, Scherer A, Shi T, Shi W, Sung J, Thierry-Mieg D, Thierry-Mieg J, Thodima V, Trygg J, Vishnuvajjala L, Wang SJ, Wu J, Wu Y, Xie Q, Yousef WA, Zhang L, Zhang X, Zhong S, Zhou Y, Zhu S, Arasappan D, Bao W, Lucas AB, Berthold F, Brennan RJ, Buness A, Catalano JG, Chang C, Chen R, Cheng Y, Cui J, Czika W, Demichelis F, Deng X, Dosymbekov D, Eils R, Feng Y, Fostel J, Fulmer-Smentek S, Fuscoe JC, Gatto L, Ge W, Goldstein DR, Guo L, Halbert DN, Han J, Harris SC, Hatzis C, Herman D, Huang J, Jensen RV, Jiang R, Johnson CD, Jurman G, Kahlert Y, Khuder SA, Kohl M, Li J, Li L, Li M, Li QZ, Li S, Li Z, Liu J, Liu Y, Liu Z, Meng L, Madera M, Martinez-Murillo F, Medina I, Meehan J, Miclaus K, Moffitt RA, Montaner D, Mukherjee P, Mulligan GJ, Neville P, Nikolskaya T, Ning B, Page GP, Parker J, Parry RM, Peng X, Peterson RL, Phan JH, Quanz B, Ren Y, Riccadonna S, Roter AH, Samuelson FW, Schumacher MM, Shambaugh JD, Shi Q, Shippy R, Si S, Smalter A, Sotiriou C, Soukup M, Staedtler F, Steiner G, Stokes TH, Sun Q, Tan PY, Tang R, Tezak Z, Thorn B, Tsyganova M, Turpaz Y, Vega SC, Visintainer R, von Frese J, Wang C, Wang E, Wang J, Wang W, Westermann F, Willey JC, Woods M, Wu S, Xiao N, Xu J, Xu L, Yang L, Zeng X, Zhang J, Zhang L, Zhang M, Zhao C, Puri RK, Scherf U, Tong W, Wolfinger RD; MAQC Consortium.

Nat Biotechnol. 2010 Aug;28(8):827-38. doi: 10.1038/nbt.1665. Epub 2010 Jul 30.

32.

Primary endothelial damage is the mechanism of cardiotoxicity of tubulin-binding drugs.

Mikaelian I, Buness A, de Vera-Mudry MC, Kanwal C, Coluccio D, Rasmussen E, Char HW, Carvajal V, Hilton H, Funk J, Hoflack JC, Fielden M, Herting F, Dunn M, Suter-Dick L.

Toxicol Sci. 2010 Sep;117(1):144-51. doi: 10.1093/toxsci/kfq189. Epub 2010 Jul 12.

PMID:
20624997
33.

Mechanism of subendocardial cell proliferation in the rat and relevance for understanding drug-induced valvular heart disease in humans.

Fielden MR, Hassani M, Uppal H, Day-Lollini P, Button D, Martin RS, Garrido R, Liu X, Kolaja KL.

Exp Toxicol Pathol. 2010 Nov;62(6):607-13. doi: 10.1016/j.etp.2009.08.009. Epub 2009 Sep 24.

PMID:
19781924
34.

Erratum to "Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing".

Nioi P, Pardo ID, Sherratt PJ, Fielden MR, Gollub J, Nie A, Snyder RD.

Chem Biol Interact. 2008 Nov 25;176(2-3):252-60.

PMID:
19086139
35.

Biomarkers of carcinogenicity and their roles in drug discovery and development.

Guan P, Olaharski A, Fielden M, Roome N, Dragan Y, Sina J.

Expert Rev Clin Pharmacol. 2008 Nov;1(6):759-71. doi: 10.1586/17512433.1.6.759.

PMID:
24410606
36.

The liver pharmacological and xenobiotic gene response repertoire.

Natsoulis G, Pearson CI, Gollub J, P Eynon B, Ferng J, Nair R, Idury R, Lee MD, Fielden MR, Brennan RJ, Roter AH, Jarnagin K.

Mol Syst Biol. 2008;4:175. doi: 10.1038/msb.2008.9. Epub 2008 Mar 25.

37.

The role of early in vivo toxicity testing in drug discovery toxicology.

Fielden MR, Kolaja KL.

Expert Opin Drug Saf. 2008 Mar;7(2):107-10. doi: 10.1517/14740338.7.2.107 .

PMID:
18324874
38.

Validation of putative genomic biomarkers of nephrotoxicity in rats.

Wang EJ, Snyder RD, Fielden MR, Smith RJ, Gu YZ.

Toxicology. 2008 Apr 18;246(2-3):91-100. doi: 10.1016/j.tox.2007.12.031. Epub 2008 Jan 16.

PMID:
18289764
39.

Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.

Fielden MR, Nie A, McMillian M, Elangbam CS, Trela BA, Yang Y, Dunn RT 2nd, Dragan Y, Fransson-Stehen R, Bogdanffy M, Adams SP, Foster WR, Chen SJ, Rossi P, Kasper P, Jacobson-Kram D, Tatsuoka KS, Wier PJ, Gollub J, Halbert DN, Roter A, Young JK, Sina JF, Marlowe J, Martus HJ, Aubrecht J, Olaharski AJ, Roome N, Nioi P, Pardo I, Snyder R, Perry R, Lord P, Mattes W, Car BD; Predictive Safety Testing Consortium; Carcinogenicity Working Group.

Toxicol Sci. 2008 May;103(1):28-34. doi: 10.1093/toxsci/kfn022. Epub 2008 Feb 14.

PMID:
18281259
40.

A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals.

Fielden MR, Brennan R, Gollub J.

Toxicol Sci. 2007 Sep;99(1):90-100. Epub 2007 Jun 8.

PMID:
17557906
41.

Iconix Biosciences, Inc.

Fielden MR, Halbert DN.

Pharmacogenomics. 2007 Apr;8(4):401-5.

PMID:
17391077
42.
43.

The state-of-the-art in predictive toxicogenomics.

Fielden MR, Kolaja KL.

Curr Opin Drug Discov Devel. 2006 Jan;9(1):84-91. Review.

PMID:
16445120
44.

A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.

Fielden MR, Eynon BP, Natsoulis G, Jarnagin K, Banas D, Kolaja KL.

Toxicol Pathol. 2005;33(6):675-83.

PMID:
16239200
45.

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

Ganter B, Tugendreich S, Pearson CI, Ayanoglu E, Baumhueter S, Bostian KA, Brady L, Browne LJ, Calvin JT, Day GJ, Breckenridge N, Dunlea S, Eynon BP, Furness LM, Ferng J, Fielden MR, Fujimoto SY, Gong L, Hu C, Idury R, Judo MS, Kolaja KL, Lee MD, McSorley C, Minor JM, Nair RV, Natsoulis G, Nguyen P, Nicholson SM, Pham H, Roter AH, Sun D, Tan S, Thode S, Tolley AM, Vladimirova A, Yang J, Zhou Z, Jarnagin K.

J Biotechnol. 2005 Sep 29;119(3):219-44.

PMID:
16005536
46.

Preclinical drug safety analysis by chemogenomic profiling in the liver.

Fielden MR, Pearson C, Brennan R, Kolaja KL.

Am J Pharmacogenomics. 2005;5(3):161-71. Review.

PMID:
15952870
47.

Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.

Sun YV, Boverhof DR, Burgoon LD, Fielden MR, Zacharewski TR.

Nucleic Acids Res. 2004 Aug 24;32(15):4512-23. Print 2004.

48.

Severe retinopathy of prematurity: longitudinal observation of disease and screening implications.

Ells A, Hicks M, Fielden M, Ingram A.

Eye (Lond). 2005 Feb;19(2):138-44.

PMID:
15218516
49.

Telemedicine approach to screening for severe retinopathy of prematurity: a pilot study.

Ells AL, Holmes JM, Astle WF, Williams G, Leske DA, Fielden M, Uphill B, Jennett P, Hebert M.

Ophthalmology. 2003 Nov;110(11):2113-7.

PMID:
14597517
50.

Gemini surfactants: new synthetic vectors for gene transfection.

Kirby AJ, Camilleri P, Engberts JB, Feiters MC, Nolte RJ, Söderman O, Bergsma M, Bell PC, Fielden ML, García Rodríguez CL, Guédat P, Kremer A, McGregor C, Perrin C, Ronsin G, van Eijk MC.

Angew Chem Int Ed Engl. 2003 Apr 4;42(13):1448-57. Review.

PMID:
12698476

Supplemental Content

Loading ...
Support Center