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Items: 1 to 50 of 149

1.

AVCC 1990-2015--A journal to combine antiviral biology and antiviral chemistry enters the third era.

Field HJ.

Antivir Chem Chemother. 2015 Feb;24(1):1-2. doi: 10.1177/2040206615574801. No abstract available.

2.

Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.

Biswas S, Sukla S, Goldner T, Field HJ, Kropeit D, Paulsen D, Welbers A, Ruebsamen-Schaeff H, Zimmermann H, Birkmann A.

Antimicrob Agents Chemother. 2014 Jul;58(7):3843-52. doi: 10.1128/AAC.02641-14. Epub 2014 Apr 21.

3.

Helicase-primase inhibitors for herpes simplex virus: looking to the future of non-nucleoside inhibitors for treating herpes virus infections.

Biswas S, Sukla S, Field HJ.

Future Med Chem. 2014 Jan;6(1):45-55. doi: 10.4155/fmc.13.192. Review.

PMID:
24358947
4.

A short commentary on the review by Weller and Kuchta: the DNA helicase-primase complex as a target for herpes virus infection.

Field HJ.

Expert Opin Ther Targets. 2013 Oct;17(10):1113-4. doi: 10.1517/14728222.2013.840294. No abstract available.

PMID:
24044544
5.

Baseline sensitivity of HSV-1 and HSV-2 clinical isolates and defined acyclovir-resistant strains to the helicase-primase inhibitor pritelivir.

Field HJ, Huang ML, Lay EM, Mickleburgh I, Zimmermann H, Birkmann A.

Antiviral Res. 2013 Nov;100(2):297-9. doi: 10.1016/j.antiviral.2013.08.024. Epub 2013 Sep 8.

PMID:
24021190
6.

Antiviral agents for herpes simplex virus.

Vere Hodge RA, Field HJ.

Adv Pharmacol. 2013;67:1-38. doi: 10.1016/B978-0-12-405880-4.00001-9. Review.

PMID:
23885997
7.

Recent developments in anti-herpesvirus drugs.

Field HJ, Vere Hodge RA.

Br Med Bull. 2013;106:213-49. doi: 10.1093/bmb/ldt011. Epub 2013 Apr 17. Review.

PMID:
23596085
8.

The helicase-primase complex as a target for effective herpesvirus antivirals.

Field HJ, Mickleburgh I.

Adv Exp Med Biol. 2013;767:145-59. doi: 10.1007/978-1-4614-5037-5_7. Review.

PMID:
23161010
9.

Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus.

Field HJ, Biswas S.

Drug Resist Updat. 2011 Feb;14(1):45-51. doi: 10.1016/j.drup.2010.11.002. Epub 2010 Dec 22. Review.

PMID:
21183396
10.

Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor.

Sukla S, Biswas S, Birkmann A, Lischka P, Zimmermann H, Field HJ.

J Antimicrob Chemother. 2010 Jul;65(7):1347-52. doi: 10.1093/jac/dkq135. Epub 2010 May 7.

11.

Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant.

Sukla S, Biswas S, Birkmann A, Lischka P, Ruebsamen-Schaeff H, Zimmermann H, Field HJ.

Antiviral Res. 2010 Jul;87(1):67-73. doi: 10.1016/j.antiviral.2010.04.008. Epub 2010 Apr 24.

PMID:
20420855
12.

From print to web: a landmark transition after 20 years of publishing.

Field HJ, Galea MN.

Antivir Chem Chemother. 2009;19(6):219-20. No abstract available.

PMID:
19641230
13.
14.
15.
16.

Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): DNA viruses.

Field HJ, De Clercq E.

Antivir Chem Chemother. 2008;19(2):51-62.

PMID:
18727440
17.

Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition).

Field HJ.

Antivir Chem Chemother. 2008;19(2):49-50. No abstract available.

PMID:
18727439
18.
19.

Development of a quantitative real-time TaqMan PCR assay for testing the susceptibility of feline herpesvirus-1 to antiviral compounds.

Hussein IT, Field HJ.

J Virol Methods. 2008 Sep;152(1-2):85-90. doi: 10.1016/j.jviromet.2008.05.018. Epub 2008 Jul 2.

PMID:
18597862
20.

Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity.

Biswas S, Tiley LS, Zimmermann H, Birkmann A, Field HJ.

Antiviral Res. 2008 Oct;80(1):81-5. doi: 10.1016/j.antiviral.2008.04.005. Epub 2008 May 16.

PMID:
18539344
21.

Penciclovir is a potent inhibitor of feline herpesvirus-1 with susceptibility determined at the level of virus-encoded thymidine kinase.

Hussein IT, Menashy RV, Field HJ.

Antiviral Res. 2008 Jun;78(3):268-74. doi: 10.1016/j.antiviral.2007.10.015. Epub 2008 Feb 12.

PMID:
18325606
22.

A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target.

Biswas S, Kleymann G, Swift M, Tiley LS, Lyall J, Aguirre-Hernández J, Field HJ.

J Antimicrob Chemother. 2008 May;61(5):1044-7. doi: 10.1093/jac/dkn057. Epub 2008 Feb 25.

PMID:
18299638
23.

Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.

Hussein IT, Miguel RN, Tiley LS, Field HJ.

Arch Virol. 2008;153(3):495-505. doi: 10.1007/s00705-007-0021-6. Epub 2008 Jan 15.

PMID:
18196203
24.
26.
28.

Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile 2006 (1st edition).

De Clercq E, Brancale A, Hodge AV, Field HJ.

Antivir Chem Chemother. 2006;17(3):113-66.

PMID:
16956068
29.

Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile 2006 (1st edition).

Field HJ, Hodge AV, Brancale A, Otto M, Sidwells R, Baba M.

Antivir Chem Chemother. 2006;17(3):111-2. No abstract available.

PMID:
16956067
30.

Herpesvirus latency and therapy--from a veterinary perspective.

Field HJ, Biswas S, Mohammad IT.

Antiviral Res. 2006 Sep;71(2-3):127-33. Epub 2006 Jun 27. Review.

PMID:
16843537
31.
32.
33.

ME-609: a treatment for recurrent herpes simplex virus infections.

Harmenberg JG, Awan AR, Alenius S, Ståhle L, Erlandsson AC, Lekare G, Flink O, Augustsson E, Larsson T, Wikström AC, Stierna P, Field HJ, Larsson AG, Oberg B.

Antivir Chem Chemother. 2003 Jul;14(4):205-15.

PMID:
14582849
34.

Ganciclovir and penciclovir, but not acyclovir, induce apoptosis in herpes simplex virus thymidine kinase-transformed baby hamster kidney cells.

Shaw MM, Gürr WK, Watts PA, Littler E, Field HJ.

Antivir Chem Chemother. 2001 May;12(3):175-86.

PMID:
12959326
35.

Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.

Shaw MM, Gürr WK, Thackray AM, Watts PA, Littler E, Field HJ.

J Virol Methods. 2002 Apr;102(1-2):93-102.

PMID:
11879697
36.

Neuronal latency in human and animal herpesvirus infections.

Borchers K, Field HJ.

Curr Top Microbiol Immunol. 2001;253:61-94. Review. No abstract available.

PMID:
11417140
37.

Herpes simplex virus antiviral drug resistance--current trends and future prospects.

Field HJ.

J Clin Virol. 2001 Jun;21(3):261-9. Review.

PMID:
11397663
39.
40.

Early therapy with valaciclovir or famciclovir reduces but does not abrogate herpes simplex virus neuronal latency.

Field HJ, Thackray AM.

Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):461-70.

PMID:
10772727
41.
42.
44.

Herpes simplex virus latency and nucleoside analogues.

Efstathiou S, Field HJ, Griffiths PD, Kern ER, Sacks SL, Sawtell NM, Stanberry LR.

Antiviral Res. 1999 Apr;41(3):85-100. Review. No abstract available.

PMID:
10320042
45.
46.

Protective effects of equine herpesvirus-1 (EHV-1) glycoprotein B in a murine model of EHV-1-induced abortion.

Kukreja A, Walker C, Fitzmaurice T, Awan A, Love DN, Whalley JM, Field HJ.

Vet Microbiol. 1998 Aug 15;62(4):303-11.

PMID:
9791876
47.

A serological study of canine herpes virus-1 infection in the English dog population.

Reading MJ, Field HJ.

Arch Virol. 1998;143(8):1477-88.

PMID:
9739327
48.

Virological and molecular biological investigations into equine herpes virus type 2 (EHV-2) experimental infections.

Borchers K, Wolfinger U, Ludwig H, Thein P, Baxi S, Field HJ, Slater JD.

Virus Res. 1998 May;55(1):101-6.

PMID:
9712516
49.
50.

Can HSV latency be conquered by current antiviral therapies?

Simmons A, Field HJ.

Sex Transm Infect. 1998 Feb;74(1):1-2. No abstract available.

PMID:
9634293

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