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Non-coding RNAs: Key players in cardiac disease.

Kreutzer FP, Fiedler J, Thum T.

J Physiol. 2019 Jul 10. doi: 10.1113/JP278131. [Epub ahead of print]


High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers.

Honěk J, Šrámek M, Šefc L, Januška J, Fiedler J, Horváth M, Tomek A, Novotný Š, Honěk T, Veselka J.

J Cardiol. 2019 Jun 26. pii: S0914-5087(19)30144-3. doi: 10.1016/j.jjcc.2019.04.014. [Epub ahead of print]


Therapeutic modulation of RNA-binding protein Rbm38 facilitates re-endothelialization after arterial injury.

Sonnenschein K, Fiedler J, Pfanne A, Just A, Mitzka S, Geffers RR, Pich A, Bauersachs J, Thum T.

Cardiovasc Res. 2019 Mar 7. pii: cvz063. doi: 10.1093/cvr/cvz063. [Epub ahead of print]


Identification of miR-143 as a Major Contributor for Human Stenotic Aortic Valve Disease.

Fiedler J, Park DH, Hobuß L, Anaraki PK, Pfanne A, Just A, Mitzka S, Dumler I, Weidemann F, Hilfiker A, Thum T.

J Cardiovasc Transl Res. 2019 Mar 6. doi: 10.1007/s12265-019-09880-7. [Epub ahead of print]


Correction to Twisting and Tilting 1,1'-Bis(dialkylphosphino)ferrocene Bound to Low Valent Tricarbonylmanganese(I to -I).

Schäfer KM, Reinders L, Fiedler J, Ringenberg MR.

Inorg Chem. 2019 Mar 4;58(5):3558. doi: 10.1021/acs.inorgchem.9b00434. Epub 2019 Feb 20. No abstract available.


CAMISIM: simulating metagenomes and microbial communities.

Fritz A, Hofmann P, Majda S, Dahms E, Dröge J, Fiedler J, Lesker TR, Belmann P, DeMaere MZ, Darling AE, Sczyrba A, Bremges A, McHardy AC.

Microbiome. 2019 Feb 8;7(1):17. doi: 10.1186/s40168-019-0633-6.


Urgent Middle Cerebral Artery Embolectomy of Calcified Embolus After Intravenous Thrombolysis: 2-Dimensional Operative Video.

Fiedler J, Ostry S, Bombic M, Sterba L, Kostal P.

Oper Neurosurg (Hagerstown). 2019 Aug 1;17(2):E54-E55. doi: 10.1093/ons/opy404.


(Spectro)electrochemical and Electrocatalytic Investigation of 1,1'-Dithiolatoferrocene-Hexacarbonyldiiron.

Häßner M, Fiedler J, Ringenberg MR.

Inorg Chem. 2019 Feb 4;58(3):1742-1745. doi: 10.1021/acs.inorgchem.8b02971. Epub 2019 Jan 17.


Hypoxia-Induced MicroRNA-212/132 Alter Blood-Brain Barrier Integrity Through Inhibition of Tight Junction-Associated Proteins in Human and Mouse Brain Microvascular Endothelial Cells.

Burek M, König A, Lang M, Fiedler J, Oerter S, Roewer N, Bohnert M, Thal SC, Blecharz-Lang KG, Woitzik J, Thum T, Förster CY.

Transl Stroke Res. 2019 Jan 8. doi: 10.1007/s12975-018-0683-2. [Epub ahead of print]


Vascular Smooth Muscle Cell Remodeling.

Fiedler J, Thum T.

Circ Res. 2018 Dec 7;123(12):1261-1263. doi: 10.1161/CIRCRESAHA.118.314184. No abstract available.


Publisher Correction: MicroRNAs regulating superoxide dismutase 2 are new circulating biomarkers of heart failure.

Dubois-Deruy E, Cuvelliez M, Fiedler J, Charrier H, Mulder P, Hebbar E, Pfanne A, Beseme O, Chwastyniak M, Amouyel P, Richard V, Bauters C, Thum T, Pinet F.

Sci Rep. 2018 Nov 29;8(1):17584. doi: 10.1038/s41598-018-35955-7.


Hepatitis A Virus Outbreaks Associated with Drug Use and Homelessness - California, Kentucky, Michigan, and Utah, 2017.

Foster M, Ramachandran S, Myatt K, Donovan D, Bohm S, Fiedler J, Barbeau B, Collins J, Thoroughman D, McDonald E, Ballard J, Eason J, Jorgensen C.

MMWR Morb Mortal Wkly Rep. 2018 Nov 2;67(43):1208-1210. doi: 10.15585/mmwr.mm6743a3.


A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration and mathematical modeling advantages.

Catalan-Figueroa J, Boisset CB, Jara MO, Flores ME, Moreno-Villoslada I, Fiedler JL, Morales JO.

Eur J Pharm Sci. 2018 Dec 1;125:215-222. doi: 10.1016/j.ejps.2018.10.002. Epub 2018 Oct 9.


Food Protein-Induced Enterocolitis Syndrome Food Challenges: Experience from a Large Referral Center.

Wang KY, Lee J, Cianferoni A, Ruffner MA, Dean A, Molleston JM, Pawlowski NA, Heimall J, Saltzman RW, Ram GS, Fiedler J, Gober LM, Spergel JM, Brown-Whitehorn TF.

J Allergy Clin Immunol Pract. 2019 Feb;7(2):444-450. doi: 10.1016/j.jaip.2018.09.009. Epub 2018 Sep 20.


Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study.

Aguayo FI, Tejos-Bravo M, Díaz-Véliz G, Pacheco A, García-Rojo G, Corrales W, Olave FA, Aliaga E, Ulloa JL, Avalos AM, Román-Albasini L, Rojas PS, Fiedler JL.

Front Mol Neurosci. 2018 Aug 17;11:283. doi: 10.3389/fnmol.2018.00283. eCollection 2018.


Multifunctional Enzyme Packaging and Catalysis in the Qβ Protein Nanoparticle.

Fiedler JD, Fishman MR, Brown SD, Lau J, Finn MG.

Biomacromolecules. 2018 Oct 8;19(10):3945-3957. doi: 10.1021/acs.biomac.8b00885. Epub 2018 Aug 30.


Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease.

Russell AL, Tasker JG, Lucion AB, Fiedler J, Munhoz CD, Wu TJ, Deak T.

J Neuroendocrinol. 2018 Oct;30(10):e12641. doi: 10.1111/jne.12641. Epub 2018 Oct 7. Review.


MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology.

Muñoz-Llanos M, García-Pérez MA, Xu X, Tejos-Bravo M, Vidal EA, Moyano TC, Gutiérrez RA, Aguayo FI, Pacheco A, García-Rojo G, Aliaga E, Rojas PS, Cidlowski JA, Fiedler JL.

Front Mol Neurosci. 2018 Aug 6;11:251. doi: 10.3389/fnmol.2018.00251. eCollection 2018.


Differences in egg and milk food challenge outcomes based on tolerance to the baked form.

Capucilli P, Cianferoni A, Fiedler J, Gober L, Pawlowski N, Ram G, Saltzman R, Spergel JM, Heimall J.

Ann Allergy Asthma Immunol. 2018 Nov;121(5):580-587. doi: 10.1016/j.anai.2018.07.018. Epub 2018 Jul 21.


Genomic prediction accuracy for switchgrass traits related to bioenergy within differentiated populations.

Fiedler JD, Lanzatella C, Edmé SJ, Palmer NA, Sarath G, Mitchell R, Tobias CM.

BMC Plant Biol. 2018 Jul 9;18(1):142. doi: 10.1186/s12870-018-1360-z.


Non-coding RNAs in vascular disease - from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.

Fiedler J, Baker AH, Dimmeler S, Heymans S, Mayr M, Thum T.

Cardiovasc Res. 2018 Aug 1;114(10):1281-1286. doi: 10.1093/cvr/cvy121.


Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalized medicine?

de Gonzalo-Calvo D, Vea A, Bär C, Fiedler J, Couch LS, Brotons C, Llorente-Cortes V, Thum T.

Eur Heart J. 2019 May 21;40(20):1643-1650. doi: 10.1093/eurheartj/ehy234.


Orientational Dependence of the van der Waals Interactions for Finite-Sized Particles.

Fiedler J, Persson C, Boström M, Buhmann SY.

J Phys Chem A. 2018 May 17;122(19):4663-4669. doi: 10.1021/acs.jpca.8b01989. Epub 2018 May 3.


Using the Five Domains Model to Assess the Adverse Impacts of Husbandry, Veterinary, and Equitation Interventions on Horse Welfare.

McGreevy P, Berger J, de Brauwere N, Doherty O, Harrison A, Fiedler J, Jones C, McDonnell S, McLean A, Nakonechny L, Nicol C, Preshaw L, Thomson P, Tzioumis V, Webster J, Wolfensohn S, Yeates J, Jones B.

Animals (Basel). 2018 Mar 18;8(3). pii: E41. doi: 10.3390/ani8030041.


At the Borderline between Metal-Metal Mixed Valency and a Radical Bridge Situation: Four Charge States of a Diruthenium Complex with a Redox-Active Bis( mer-tridentate) Ligand.

Mondal S, Schwederski B, Frey W, Fiedler J, Záliš S, Kaim W.

Inorg Chem. 2018 Apr 2;57(7):3983-3992. doi: 10.1021/acs.inorgchem.8b00173. Epub 2018 Mar 12.


Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in zebrafish.

Müller-Deile J, Schröder P, Beverly-Staggs L, Hiss R, Fiedler J, Nyström J, Thum T, Haller H, Schiffer M.

Sci Rep. 2018 Feb 26;8(1):3621. doi: 10.1038/s41598-018-22070-w.


Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia.

Bhayadia R, Krowiorz K, Haetscher N, Jammal R, Emmrich S, Obulkasim A, Fiedler J, Schwarzer A, Rouhi A, Heuser M, Wingert S, Bothur S, Döhner K, Mätzig T, Ng M, Reinhardt D, Döhner H, Zwaan CM, van den Heuvel Eibrink M, Heckl D, Fornerod M, Thum T, Humphries RK, Rieger MA, Kuchenbauer F, Klusmann JH.

J Clin Oncol. 2018 Apr 1;36(10):1007-1016. doi: 10.1200/JCO.2017.75.2204. Epub 2018 Feb 12.


Matrix Metalloproteinase 9 Displays a Particular Time Response to Acute Stress: Variation in Its Levels and Activity Distribution in Rat Hippocampus.

Aguayo FI, Pacheco AA, García-Rojo GJ, Pizarro-Bauerle JA, Doberti AV, Tejos M, García-Pérez MA, Rojas PS, Fiedler JL.

ACS Chem Neurosci. 2018 May 16;9(5):945-956. doi: 10.1021/acschemneuro.7b00387. Epub 2018 Feb 7.


Genome-Wide Association and Prediction of Grain and Semolina Quality Traits in Durum Wheat Breeding Populations.

Fiedler JD, Salsman E, Liu Y, Michalak de Jiménez M, Hegstad JB, Chen B, Manthey FA, Chao S, Xu S, Elias EM, Li X.

Plant Genome. 2017 Nov;10(3). doi: 10.3835/plantgenome2017.05.0038.


Systemic recovery and therapeutic effects of transplanted allogenic and xenogenic mesenchymal stromal cells in a rat blunt chest trauma model.

Amann EM, Rojewski MT, Rodi S, Fürst D, Fiedler J, Palmer A, Braumüller S, Huber-Lang M, Schrezenmeier H, Brenner RE.

Cytotherapy. 2018 Feb;20(2):218-231. doi: 10.1016/j.jcyt.2017.11.005. Epub 2017 Dec 7.


Genetic mapping of a major gene in triticale conferring resistance to bacterial leaf streak.

Wen A, Jayawardana M, Fiedler J, Sapkota S, Shi G, Peng Z, Liu S, White FF, Bogdanove AJ, Li X, Liu Z.

Theor Appl Genet. 2018 Mar;131(3):649-658. doi: 10.1007/s00122-017-3026-x. Epub 2017 Dec 7.


Effective Polarizability Models.

Fiedler J, Thiyam P, Kurumbail A, Burger FA, Walter M, Persson C, Brevik I, Parsons DF, Boström M, Buhmann SY.

J Phys Chem A. 2017 Dec 28;121(51):9742-9751. doi: 10.1021/acs.jpca.7b10159. Epub 2017 Dec 15.


Isomeric Diruthenium Complexes Bridged by Deprotonated Indigo in cis and trans Configuration.

Chatterjee M, Ghosh P, Beyer K, Paretzki A, Fiedler J, Kaim W, Lahiri GK.

Chem Asian J. 2018 Jan 4;13(1):118-125. doi: 10.1002/asia.201701562. Epub 2017 Dec 12.


Twisting and Tilting l,l'-Bis(dialkylphosphino)ferrocene Bound to Low Valent Tricarbonylmaganese(I to -I). [corrected].

Schäfer KM, Reinders L, Fiedler J, Ringenberg MR.

Inorg Chem. 2017 Dec 4;56(23):14688-14696. doi: 10.1021/acs.inorgchem.7b02627. Epub 2017 Nov 16. Erratum in: Inorg Chem. 2019 Mar 4;58(5):3558.


miRNome Profiling of Purified Endoderm and Mesoderm Differentiated from hESCs Reveals Functions of miR-483-3p and miR-1263 for Cell-Fate Decisions.

Ishikawa D, Diekmann U, Fiedler J, Just A, Thum T, Lenzen S, Naujok O.

Stem Cell Reports. 2017 Nov 14;9(5):1588-1603. doi: 10.1016/j.stemcr.2017.10.011.


Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.

Gupta SK, Garg A, Bär C, Chatterjee S, Foinquinos A, Milting H, Streckfuß-Bömeke K, Fiedler J, Thum T.

Circ Res. 2018 Jan 19;122(2):246-254. doi: 10.1161/CIRCRESAHA.117.311335. Epub 2017 Nov 13.


MicroRNAs regulating superoxide dismutase 2 are new circulating biomarkers of heart failure.

Dubois-Deruy E, Cuvelliez M, Fiedler J, Charrier H, Mulder P, Hebbar E, Pfanne A, Beseme O, Chwastyniak M, Amouyel P, Richard V, Bauters C, Thum T, Pinet F.

Sci Rep. 2017 Nov 7;7(1):14747. doi: 10.1038/s41598-017-15011-6. Erratum in: Sci Rep. 2018 Nov 29;8(1):17584.


Dual effect of serotonin on the dendritic growth of cultured hippocampal neurons: Involvement of 5-HT1A and 5-HT7 receptors.

Rojas PS, Aguayo F, Neira D, Tejos M, Aliaga E, Muñoz JP, Parra CS, Fiedler JL.

Mol Cell Neurosci. 2017 Dec;85:148-161. doi: 10.1016/j.mcn.2017.09.009. Epub 2017 Sep 30.


Critical Assessment of Metagenome Interpretation-a benchmark of metagenomics software.

Sczyrba A, Hofmann P, Belmann P, Koslicki D, Janssen S, Dröge J, Gregor I, Majda S, Fiedler J, Dahms E, Bremges A, Fritz A, Garrido-Oter R, Jørgensen TS, Shapiro N, Blood PD, Gurevich A, Bai Y, Turaev D, DeMaere MZ, Chikhi R, Nagarajan N, Quince C, Meyer F, Balvočiūtė M, Hansen LH, Sørensen SJ, Chia BKH, Denis B, Froula JL, Wang Z, Egan R, Don Kang D, Cook JJ, Deltel C, Beckstette M, Lemaitre C, Peterlongo P, Rizk G, Lavenier D, Wu YW, Singer SW, Jain C, Strous M, Klingenberg H, Meinicke P, Barton MD, Lingner T, Lin HH, Liao YC, Silva GGZ, Cuevas DA, Edwards RA, Saha S, Piro VC, Renard BY, Pop M, Klenk HP, Göker M, Kyrpides NC, Woyke T, Vorholt JA, Schulze-Lefert P, Rubin EM, Darling AE, Rattei T, McHardy AC.

Nat Methods. 2017 Nov;14(11):1063-1071. doi: 10.1038/nmeth.4458. Epub 2017 Oct 2.


Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats.

Pacheco A, Aguayo FI, Aliaga E, Muñoz M, García-Rojo G, Olave FA, Parra-Fiedler NA, García-Pérez A, Tejos-Bravo M, Rojas PS, Parra CS, Fiedler JL.

Front Mol Neurosci. 2017 Aug 10;10:244. doi: 10.3389/fnmol.2017.00244. eCollection 2017.


Oxidation of Natural Bioactive Flavonolignan 2,3-Dehydrosilybin: An Electrochemical and Spectral Study.

Sokolová R, Kocábová J, Marhol P, Fiedler J, Biedermann D, Vacek J, Křen V.

J Phys Chem B. 2017 Jul 20;121(28):6841-6846. doi: 10.1021/acs.jpcb.7b04651. Epub 2017 Jul 11.


Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.

Gonzalez-Gronow M, Fiedler JL, Farias Gomez C, Wang F, Ray R, Ferrell PD, Pizzo SV.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):855-860. doi: 10.1016/j.bbrc.2017.06.131. Epub 2017 Jun 23.


Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases.

Müller-Deile J, Dannenberg J, Schroder P, Lin MH, Miner JH, Chen R, Bräsen JH, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M.

Kidney Int. 2017 Oct;92(4):836-849. doi: 10.1016/j.kint.2017.03.005. Epub 2017 May 3.


Inhibition of miRNA-212/132 improves the reprogramming of fibroblasts into induced pluripotent stem cells by de-repressing important epigenetic remodelling factors.

Pfaff N, Liebhaber S, Möbus S, Beh-Pajooh A, Fiedler J, Pfanne A, Schambach A, Thum T, Cantz T, Moritz T.

Stem Cell Res. 2017 Apr;20:70-75. doi: 10.1016/j.scr.2017.03.003. Epub 2017 Mar 7.


Inferior sinus venosus and two ostium secundum atrial septal defects is possible to treat with three occluders.

Hajek P, Palenickova J, Fiedler J, Horvath M, Suchanek V, Veselka J.

Arch Med Sci. 2017 Feb 1;13(1):260-262. doi: 10.5114/aoms.2016.64041. Epub 2016 Nov 29. No abstract available.


Local Proton Source in Electrocatalytic CO2 Reduction with [Mn(bpy-R)(CO)3 Br] Complexes.

Franco F, Cometto C, Nencini L, Barolo C, Sordello F, Minero C, Fiedler J, Robert M, Gobetto R, Nervi C.

Chemistry. 2017 Apr 6;23(20):4782-4793. doi: 10.1002/chem.201605546. Epub 2017 Feb 22.


SONOlysis in prevention of Brain InfaRctions During Internal carotid Endarterectomy (SONOBIRDIE) trial - study protocol for a randomized controlled trial.

Hrbáč T, Netuka D, Beneš V, Nosáľ V, Kešnerová P, Tomek A, Fadrná T, Beneš V Jr, Fiedler J, Přibáň V, Brozman M, Langová K, Herzig R, Školoudík D.

Trials. 2017 Jan 17;18(1):25. doi: 10.1186/s13063-016-1754-x.


What Do We Really Know About 5-HT1A Receptor Signaling in Neuronal Cells?

Rojas PS, Fiedler JL.

Front Cell Neurosci. 2016 Nov 24;10:272. eCollection 2016. Review.


The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus.

García-Rojo G, Fresno C, Vilches N, Díaz-Véliz G, Mora S, Aguayo F, Pacheco A, Parra-Fiedler N, Parra CS, Rojas PS, Tejos M, Aliaga E, Fiedler JL.

Int J Neuropsychopharmacol. 2017 Apr 1;20(4):336-345. doi: 10.1093/ijnp/pyw108.

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