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Items: 1 to 50 of 98

1.

ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer.

Rose M, Bringezu S, Godfrey L, Fiedler D, Gaisa NT, Koch M, Bach C, Füssel S, Herr A, Hübner D, Ellinger J, Pfister D, Knüchel R, Wirth MP, Böhme M, Dahl E.

Int J Mol Sci. 2020 Feb 7;21(3). pii: E1117. doi: 10.3390/ijms21031117.

2.

Control of XPR1-dependent cellular phosphate efflux by InsP8 is an exemplar for functionally-exclusive inositol pyrophosphate signaling.

Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB.

Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3568-3574. doi: 10.1073/pnas.1908830117. Epub 2020 Feb 4.

PMID:
32019887
3.

Conceptual Characterization of Threshold Concepts in Student Explanations of Evolution by Natural Selection and Effects of Item Context.

Göransson A, Orraryd D, Fiedler D, Tibell LAE.

CBE Life Sci Educ. 2020 Mar;19(1):ar1. doi: 10.1187/cbe.19-03-0056.

4.

Evidence for impaired extinction learning in humans after distal stress exposure.

Klinke CM, Fiedler D, Lange MD, Andreatta M.

Neurobiol Learn Mem. 2020 Jan;167:107127. doi: 10.1016/j.nlm.2019.107127. Epub 2019 Nov 22.

5.

Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates.

Puschmann R, Harmel RK, Fiedler D.

Biochemistry. 2019 Sep 24;58(38):3927-3932. doi: 10.1021/acs.biochem.9b00587. Epub 2019 Sep 14.

PMID:
31461621
6.

Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis.

Zhu J, Lau K, Puschmann R, Harmel RK, Zhang Y, Pries V, Gaugler P, Broger L, Dutta AK, Jessen HJ, Schaaf G, Fernie AR, Hothorn LA, Fiedler D, Hothorn M.

Elife. 2019 Aug 22;8. pii: e43582. doi: 10.7554/eLife.43582.

7.

Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes.

Fiedler D, Hirsch D, El Hajj N, Yang HH, Hu Y, Sticht C, Nanda I, Belle S, Rueschoff J, Lee MP, Ried T, Haaf T, Gaiser T.

Genes Chromosomes Cancer. 2019 Nov;58(11):783-797. doi: 10.1002/gcc.22787. Epub 2019 Aug 10.

PMID:
31334584
8.

Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR.

Harmel RK, Puschmann R, Nguyen Trung M, Saiardi A, Schmieder P, Fiedler D.

Chem Sci. 2019 Apr 23;10(20):5267-5274. doi: 10.1039/c9sc00151d. eCollection 2019 May 28.

9.

Electron Transfer/Higher Energy Collisional Dissociation of Doubly Charged Peptide Ions: Identification of Labile Protein Phosphorylations.

Penkert M, Hauser A, Harmel R, Fiedler D, Hackenberger CPR, Krause E.

J Am Soc Mass Spectrom. 2019 Sep;30(9):1578-1585. doi: 10.1007/s13361-019-02240-4. Epub 2019 May 20.

PMID:
31111417
10.

Factors Affecting Operative Duration in Isolated Open Carpal Tunnel Release.

Hinds RM, Fiedler DK, Capo JT, Yang SS.

J Wrist Surg. 2019 Apr;8(2):108-111. doi: 10.1055/s-0038-1672154. Epub 2018 Sep 27.

11.

Siloxane in baking moulds, emission to indoor air and migration to food during baking with an electric oven.

Fromme H, Witte M, Fembacher L, Gruber L, Hagl T, Smolic S, Fiedler D, Sysoltseva M, Schober W.

Environ Int. 2019 May;126:145-152. doi: 10.1016/j.envint.2019.01.081. Epub 2019 Feb 21.

12.

Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence.

Fiedler D, Heselmeyer-Haddad K, Hirsch D, Hernandez LS, Torres I, Wangsa D, Hu Y, Zapata L, Rueschoff J, Belle S, Ried T, Gaiser T.

Int J Cancer. 2019 Apr 1;144(7):1561-1573. doi: 10.1002/ijc.31869. Epub 2018 Dec 11.

13.

Pyrophosphorylation via selective phosphoprotein derivatization.

Marmelstein AM, Morgan JAM, Penkert M, Rogerson DT, Chin JW, Krause E, Fiedler D.

Chem Sci. 2018 Jun 12;9(27):5929-5936. doi: 10.1039/c8sc01233d. eCollection 2018 Jul 21.

14.

Crop pests and predators exhibit inconsistent responses to surrounding landscape composition.

Karp DS, Chaplin-Kramer R, Meehan TD, Martin EA, DeClerck F, Grab H, Gratton C, Hunt L, Larsen AE, Martínez-Salinas A, O'Rourke ME, Rusch A, Poveda K, Jonsson M, Rosenheim JA, Schellhorn NA, Tscharntke T, Wratten SD, Zhang W, Iverson AL, Adler LS, Albrecht M, Alignier A, Angelella GM, Zubair Anjum M, Avelino J, Batáry P, Baveco JM, Bianchi FJJA, Birkhofer K, Bohnenblust EW, Bommarco R, Brewer MJ, Caballero-López B, Carrière Y, Carvalheiro LG, Cayuela L, Centrella M, Ćetković A, Henri DC, Chabert A, Costamagna AC, De la Mora A, de Kraker J, Desneux N, Diehl E, Diekötter T, Dormann CF, Eckberg JO, Entling MH, Fiedler D, Franck P, Frank van Veen FJ, Frank T, Gagic V, Garratt MPD, Getachew A, Gonthier DJ, Goodell PB, Graziosi I, Groves RL, Gurr GM, Hajian-Forooshani Z, Heimpel GE, Herrmann JD, Huseth AS, Inclán DJ, Ingrao AJ, Iv P, Jacot K, Johnson GA, Jones L, Kaiser M, Kaser JM, Keasar T, Kim TN, Kishinevsky M, Landis DA, Lavandero B, Lavigne C, Le Ralec A, Lemessa D, Letourneau DK, Liere H, Lu Y, Lubin Y, Luttermoser T, Maas B, Mace K, Madeira F, Mader V, Cortesero AM, Marini L, Martinez E, Martinson HM, Menozzi P, Mitchell MGE, Miyashita T, Molina GAR, Molina-Montenegro MA, O'Neal ME, Opatovsky I, Ortiz-Martinez S, Nash M, Östman Ö, Ouin A, Pak D, Paredes D, Parsa S, Parry H, Perez-Alvarez R, Perović DJ, Peterson JA, Petit S, Philpott SM, Plantegenest M, Plećaš M, Pluess T, Pons X, Potts SG, Pywell RF, Ragsdale DW, Rand TA, Raymond L, Ricci B, Sargent C, Sarthou JP, Saulais J, Schäckermann J, Schmidt NP, Schneider G, Schüepp C, Sivakoff FS, Smith HG, Stack Whitney K, Stutz S, Szendrei Z, Takada MB, Taki H, Tamburini G, Thomson LJ, Tricault Y, Tsafack N, Tschumi M, Valantin-Morison M, Van Trinh M, van der Werf W, Vierling KT, Werling BP, Wickens JB, Wickens VJ, Woodcock BA, Wyckhuys K, Xiao H, Yasuda M, Yoshioka A, Zou Y.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7863-E7870. doi: 10.1073/pnas.1800042115. Epub 2018 Aug 2.

15.

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE.

Mol Cell. 2018 Jun 7;70(5):936-948.e7. doi: 10.1016/j.molcel.2018.05.010. Epub 2018 Jun 7.

16.

Oxytocin Signaling in the Lateral Septum Prevents Social Fear during Lactation.

Menon R, Grund T, Zoicas I, Althammer F, Fiedler D, Biermeier V, Bosch OJ, Hiraoka Y, Nishimori K, Eliava M, Grinevich V, Neumann ID.

Curr Biol. 2018 Apr 2;28(7):1066-1078.e6. doi: 10.1016/j.cub.2018.02.044. Epub 2018 Mar 15.

17.

Features and regulation of non-enzymatic post-translational modifications.

Harmel R, Fiedler D.

Nat Chem Biol. 2018 Feb 14;14(3):244-252. doi: 10.1038/nchembio.2575. Review.

PMID:
29443975
18.

Methodological strategies in using home sleep apnea testing in research and practice.

Miller JN, Schulz P, Pozehl B, Fiedler D, Fial A, Berger AM.

Sleep Breath. 2018 Sep;22(3):569-577. doi: 10.1007/s11325-017-1593-3. Epub 2017 Nov 14. Review.

PMID:
29139016
19.

University Students' Conceptual Knowledge of Randomness and Probability in the Contexts of Evolution and Mathematics.

Fiedler D, Tröbst S, Harms U.

CBE Life Sci Educ. 2017 Summer;16(2). pii: ar38. doi: 10.1187/cbe.16-07-0230.

20.

Unambiguous Identification of Serine and Threonine Pyrophosphorylation Using Neutral-Loss-Triggered Electron-Transfer/Higher-Energy Collision Dissociation.

Penkert M, Yates LM, Schümann M, Perlman D, Fiedler D, Krause E.

Anal Chem. 2017 Mar 21;89(6):3672-3680. doi: 10.1021/acs.analchem.6b05095. Epub 2017 Mar 3.

PMID:
28218834
21.

Chemical Approaches to Studying Labile Amino Acid Phosphorylation.

Marmelstein AM, Moreno J, Fiedler D.

Top Curr Chem (Cham). 2017 Apr;375(2):22. doi: 10.1007/s41061-017-0111-1. Epub 2017 Feb 6. Review.

PMID:
28168647
22.

Nail Bed Reconstruction Using Single-Layer Bovine Acellular Dermal Matrix.

Fiedler DK, Barrett JE, Lourie GM.

J Hand Surg Am. 2017 Jan;42(1):e67-e74. doi: 10.1016/j.jhsa.2016.10.010. Review.

PMID:
28052837
23.

Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms.

Wu M, Chong LS, Perlman DH, Resnick AC, Fiedler D.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6757-E6765. Epub 2016 Oct 19.

24.

Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport.

Chanduri M, Rai A, Malla AB, Wu M, Fiedler D, Mallik R, Bhandari R.

Biochem J. 2016 Oct 1;473(19):3031-47. doi: 10.1042/BCJ20160610. Epub 2016 Jul 29.

25.

Chemical tools for interrogating inositol pyrophosphate structure and function.

Brown NW, Marmelstein AM, Fiedler D.

Chem Soc Rev. 2016 Nov 7;45(22):6311-6326. Review.

PMID:
27462803
26.

Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues.

Hager A, Wu M, Wang H, Brown NW Jr, Shears SB, Veiga N, Fiedler D.

Chemistry. 2016 Aug 22;22(35):12406-14. doi: 10.1002/chem.201601754. Epub 2016 Jul 27.

27.

Prosthetics in antiquity-An early medieval wearer of a foot prosthesis (6th century AD) from Hemmaberg/Austria.

Binder M, Eitler J, Deutschmann J, Ladstätter S, Glaser F, Fiedler D.

Int J Paleopathol. 2016 Mar;12:29-40. doi: 10.1016/j.ijpp.2015.11.003. Epub 2015 Dec 8.

PMID:
29539518
28.

A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5).

Steidle EA, Chong LS, Wu M, Crooke E, Fiedler D, Resnick AC, Rolfes RJ.

J Biol Chem. 2016 Mar 25;291(13):6772-83. doi: 10.1074/jbc.M116.714907. Epub 2016 Jan 31.

29.

A Stable Pyrophosphoserine Analog for Incorporation into Peptides and Proteins.

Yates LM, Fiedler D.

ACS Chem Biol. 2016 Apr 15;11(4):1066-73. doi: 10.1021/acschembio.5b00972. Epub 2016 Feb 5.

PMID:
26760216
30.

Designing Technology to Decrease Pneumonia in Intubated Trauma Patients.

Swearer JN, Hammer CL, Matthews SM, Meunier JL, Medler KL, Kamer GS, Fiedler DM, Johnston CL, Schmitt KR, Sawyer AJ.

J Trauma Nurs. 2015 Sep-Oct;22(5):282-9. doi: 10.1097/JTN.0000000000000155.

PMID:
26352660
31.

Rapid identification of polystyrene foam wastes containing hexabromocyclododecane or its alternative polymeric brominated flame retardant by X-ray fluorescence spectroscopy.

Schlummer M, Vogelsang J, Fiedler D, Gruber L, Wolz G.

Waste Manag Res. 2015 Jul;33(7):662-70. doi: 10.1177/0734242X15589783. Epub 2015 Jun 29.

PMID:
26123348
32.

A Fluorescent Sensor and Gel Stain for Detection of Pyrophosphorylated Proteins.

Williams FJ, Fiedler D.

ACS Chem Biol. 2015 Sep 18;10(9):1958-63. doi: 10.1021/acschembio.5b00256. Epub 2015 Jun 22.

PMID:
26061479
33.

Differential genetic interactions of yeast stress response MAPK pathways.

Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ.

Mol Syst Biol. 2015 Apr 17;11(4):800. doi: 10.15252/msb.20145606.

34.

Perfluoroalkyl and polyfluoroalkyl substances in consumer products.

Kotthoff M, Müller J, Jürling H, Schlummer M, Fiedler D.

Environ Sci Pollut Res Int. 2015 Oct;22(19):14546-59. doi: 10.1007/s11356-015-4202-7. Epub 2015 Feb 19.

35.

An affinity reagent for the recognition of pyrophosphorylated peptides.

Conway JH, Fiedler D.

Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3941-5. doi: 10.1002/anie.201411232. Epub 2015 Feb 4.

PMID:
25651128
36.

Establishing the stability and reversibility of protein pyrophosphorylation with synthetic peptides.

Yates LM, Fiedler D.

Chembiochem. 2015 Feb 9;16(3):415-23. doi: 10.1002/cbic.201402589. Epub 2015 Jan 30.

PMID:
25639821
37.

Multi-resolution voxel phantom modeling: a high-resolution eye model for computational dosimetry.

Caracappa PF, Rhodes A, Fiedler D.

Phys Med Biol. 2014 Sep 21;59(18):5261-75. doi: 10.1088/0031-9155/59/18/5261. Epub 2014 Aug 21.

PMID:
25144465
38.

Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues.

Wu M, Chong LS, Capolicchio S, Jessen HJ, Resnick AC, Fiedler D.

Angew Chem Int Ed Engl. 2014 Jul 7;53(28):7192-7. doi: 10.1002/anie.201402905. Epub 2014 May 30.

PMID:
24888434
39.

Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.

Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH.

Mol Cell. 2014 Apr 10;54(1):119-132. doi: 10.1016/j.molcel.2014.02.020. Epub 2014 Mar 20.

40.

Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.

Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM.

Cell Rep. 2013 Dec 26;5(6):1725-36. doi: 10.1016/j.celrep.2013.11.040. Epub 2013 Dec 19.

41.

Chemical pyrophosphorylation of functionally diverse peptides.

Marmelstein AM, Yates LM, Conway JH, Fiedler D.

J Am Chem Soc. 2014 Jan 8;136(1):108-11. doi: 10.1021/ja411737c. Epub 2013 Dec 26.

42.

Epigenetic inactivation of ITIH5 promotes bladder cancer progression and predicts early relapse of pT1 high-grade urothelial tumours.

Rose M, Gaisa NT, Antony P, Fiedler D, Heidenreich A, Otto W, Denzinger S, Bertz S, Hartmann A, Karl A, Knüchel R, Dahl E.

Carcinogenesis. 2014 Mar;35(3):727-36. doi: 10.1093/carcin/bgt375. Epub 2013 Nov 21.

PMID:
24265292
43.

Impact of industrial production and packaging processes on the concentration of per- and polyfluorinated compounds in milk and dairy products.

Still M, Schlummer M, Gruber L, Fiedler D, Wolz G.

J Agric Food Chem. 2013 Sep 25;61(38):9052-62. doi: 10.1021/jf4020137. Epub 2013 Sep 16.

PMID:
24000959
44.

Detection of fluorotelomer alcohols in indoor environments and their relevance for human exposure.

Schlummer M, Gruber L, Fiedler D, Kizlauskas M, Müller J.

Environ Int. 2013 Jul;57-58:42-9. doi: 10.1016/j.envint.2013.03.010. Epub 2013 May 5.

PMID:
23651837
45.
46.

Chronic pancreatitis: early results of pancreatoduodenectomy and analysis of risk factors.

Rückert F, Kersting S, Fiedler D, Distler M, Dobrowolski F, Pilarsky C, Saeger HD, Grützmann R.

Pancreas. 2011 Aug;40(6):925-30. doi: 10.1097/MPA.0b013e3182156d87.

PMID:
21487322
47.

Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.

Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K.

Cancer Res. 2011 Jan 1;71(1):106-15. doi: 10.1158/0008-5472.CAN-10-2732.

48.

Functional overlap and regulatory links shape genetic interactions between signaling pathways.

van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC.

Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021.

49.

Rewiring of genetic networks in response to DNA damage.

Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, Kolodner RD, Huh WK, Aebersold R, Keogh MC, Krogan NJ, Ideker T.

Science. 2010 Dec 3;330(6009):1385-9. doi: 10.1126/science.1195618. Erratum in: Science. 2011 Jan 21;331(6015):284.

50.

Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ.

PLoS Biol. 2009 Jun 16;7(6):e1000134. doi: 10.1371/journal.pbio.1000134. Epub 2009 Jun 23. Erratum in: PLoS Biol. 2009 Nov;7(11). doi: 10.1371/annotation/66479889-5e57-4213-bf25-c4e8cf3d933b.

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