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Items: 1 to 50 of 148

1.

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.

Grabner GF, Fawzy N, Pribasnig M, Trieb M, Taschler U, Holzer M, Schweiger M, Wolinski H, Kolb D, Horvath A, Breinbauer R, Ruelicke T, Rabl R, Lass A, Stadlbauer V, Hutter-Paier B, Stauber RE, Fickert P, Zechner R, Marsche G, Eichmann TO, Zimmermann R.

J Lipid Res. 2019 Mar 20. pii: jlr.M093351. doi: 10.1194/jlr.M093351. [Epub ahead of print]

2.

Preface - Animal models in liver disease.

Fickert P, Wagner M.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 27. pii: S0925-4439(19)30047-X. doi: 10.1016/j.bbadis.2019.02.004. [Epub ahead of print] No abstract available.

PMID:
30826179
3.

Gut pathobionts as triggers for liver diseases.

Fickert P, Marschall HU.

Nat Microbiol. 2019 Mar;4(3):380-381. doi: 10.1038/s41564-019-0388-7. No abstract available.

PMID:
30787476
4.

Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.

Liu L, Panzitt K, Racedo S, Wagner M, Platzer W, Zaufel A, Theiler-Schwetz V, Obermayer-Pietsch B, Müller H, Höfler G, Heinemann A, Zollner G, Fickert P.

Liver Int. 2019 Jan 21. doi: 10.1111/liv.14052. [Epub ahead of print]

PMID:
30664326
5.

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+-Taurocholate Cotransporting Polypeptide.

Robin MJD, Appelman MD, Vos HR, van Es RM, Paton JC, Paton AW, Burgering B, Fickert P, Heijmans J, van de Graaf SFJ.

Hepatol Commun. 2018 Oct 23;2(12):1550-1566. doi: 10.1002/hep4.1262. eCollection 2018 Dec.

6.

Bile acids and glucocorticoid metabolism in health and disease.

Theiler-Schwetz V, Zaufel A, Schlager H, Obermayer-Pietsch B, Fickert P, Zollner G.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):243-251. doi: 10.1016/j.bbadis.2018.08.001. Epub 2018 Aug 3. Review.

PMID:
30463692
7.

Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.

Kleinegger F, Hofer E, Wodlej C, Golob-Schwarzl N, Birkl-Toeglhofer AM, Stallinger A, Petzold J, Orlova A, Krassnig S, Reihs R, Niedrist T, Mangge H, Park YN, Thalhammer M, Aigelsreiter A, Lax S, Garbers C, Fickert P, Rose-John S, Moriggl R, Rinner B, Haybaeck J.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):308-321. doi: 10.1016/j.bbadis.2018.11.006. Epub 2018 Nov 9.

8.

Is This the Last Requiem for Simtuzumab?

Fickert P.

Hepatology. 2019 Feb;69(2):476-479. doi: 10.1002/hep.30309. Epub 2018 Dec 31. No abstract available.

PMID:
30303551
9.

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 161: A 42-year-old journalist with fatigue, elevated liver function tests, hyperglycemia and pruritus.

Fabian E, Peck-Radosavljevic M, Krones E, Mueller H, Lackner C, Spreizer C, Putz-Bankuti C, Fuerst W, Wutte N, Fickert P, Mischinger H, Krejs GJ.

Wien Klin Wochenschr. 2018 Sep;130(17-18):545-556. doi: 10.1007/s00508-018-1379-z. Epub 2018 Aug 21. No abstract available.

10.

NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.

Tang Y, Blomenkamp KS, Fickert P, Trauner M, Teckman JH.

PLoS One. 2018 Aug 1;13(8):e0200897. doi: 10.1371/journal.pone.0200897. eCollection 2018.

11.

Time for the dawn of multimodal therapies and the dusk for mono-therapeutic trials for cholestatic liver diseases?

Wagner M, Fickert P.

Liver Int. 2018 Jun;38(6):991-994. doi: 10.1111/liv.13744. No abstract available.

PMID:
29863313
12.

Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.

Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P.

J Hepatol. 2018 Aug;69(2):368-377. doi: 10.1016/j.jhep.2018.04.009. Epub 2018 Apr 28.

PMID:
29709678
13.

To salt or not to salt?-That is the question in cirrhosis.

Haberl J, Zollner G, Fickert P, Stadlbauer V.

Liver Int. 2018 Jul;38(7):1148-1159. doi: 10.1111/liv.13750. Epub 2018 May 16. Review.

PMID:
29608812
14.

Case of nasogastric tube dysfunction.

Rainer F, Prenner G, Binder LP, Fickert P, Plank J.

Gut. 2019 Feb;68(2):206-262. doi: 10.1136/gutjnl-2017-315619. Epub 2018 Jan 5.

PMID:
29305431
15.

Soluble CD163 and soluble mannose receptor predict survival and decompensation in patients with liver cirrhosis, and correlate with gut permeability and bacterial translocation.

Rainer F, Horvath A, Sandahl TD, Leber B, Schmerboeck B, Blesl A, Groselj-Strele A, Stauber RE, Fickert P, Stiegler P, Møller HJ, Grønbaek H, Stadlbauer V.

Aliment Pharmacol Ther. 2018 Mar;47(5):657-664. doi: 10.1111/apt.14474. Epub 2017 Dec 21.

16.

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.

Golob-Schwarzl N, Schweiger C, Koller C, Krassnig S, Gogg-Kamerer M, Gantenbein N, Toeglhofer AM, Wodlej C, Bergler H, Pertschy B, Uranitsch S, Holter M, El-Heliebi A, Fuchs J, Punschart A, Stiegler P, Keil M, Hoffmann J, Henderson D, Lehrach H, Reinhard C, Regenbrecht C, Schicho R, Fickert P, Lax S, Haybaeck J.

Oncotarget. 2017 Sep 5;8(60):101224-101243. doi: 10.18632/oncotarget.20642. eCollection 2017 Nov 24.

17.

Structural and functional differences in gut microbiome composition in patients undergoing haemodialysis or peritoneal dialysis.

Stadlbauer V, Horvath A, Ribitsch W, Schmerböck B, Schilcher G, Lemesch S, Stiegler P, Rosenkranz AR, Fickert P, Leber B.

Sci Rep. 2017 Nov 15;7(1):15601. doi: 10.1038/s41598-017-15650-9.

18.

Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).

Reiberger T, Püspök A, Schoder M, Baumann-Durchschein F, Bucsics T, Datz C, Dolak W, Ferlitsch A, Finkenstedt A, Graziadei I, Hametner S, Karnel F, Krones E, Maieron A, Mandorfer M, Peck-Radosavljevic M, Rainer F, Schwabl P, Stadlbauer V, Stauber R, Tilg H, Trauner M, Zoller H, Schöfl R, Fickert P.

Wien Klin Wochenschr. 2017 Nov;129(Suppl 3):135-158. doi: 10.1007/s00508-017-1262-3. Epub 2017 Oct 23.

19.

Cholemic nephropathy - Historical notes and novel perspectives.

Krones E, Pollheimer MJ, Rosenkranz AR, Fickert P.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1356-1366. doi: 10.1016/j.bbadis.2017.08.028. Epub 2017 Aug 26. Review.

PMID:
28851656
20.

Niacin-Associated Acute Hepatotoxicity Leading to Emergency Liver Transplantation.

Schaffellner S, Stadlbauer V, Sereinigg M, Mìller H, Högenauer C, Fickert P, Krumnikl J, Lackner C, Kniepeiss D, Stauber RE.

Am J Gastroenterol. 2017 Aug;112(8):1345-1346. doi: 10.1038/ajg.2017.171. No abstract available.

PMID:
28766583
21.

NOD2 gene variants confer risk for secondary sclerosing cholangitis in critically ill patients.

Jüngst C, Stadlbauer V, Reichert MC, Zimmer V, Weber SN, Ofner-Ziegenfuß L, Voigtländer T, Spindelböck W, Fickert P, Kirchner GI, Lammert F, Lankisch TO, Krawczyk M.

Sci Rep. 2017 Aug 1;7(1):7026. doi: 10.1038/s41598-017-06268-y.

22.

New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.

Golob-Schwarzl N, Krassnig S, Toeglhofer AM, Park YN, Gogg-Kamerer M, Vierlinger K, Schröder F, Rhee H, Schicho R, Fickert P, Haybaeck J.

Eur J Cancer. 2017 Sep;83:56-70. doi: 10.1016/j.ejca.2017.06.003. Epub 2017 Jul 14.

PMID:
28715695
23.

Biliary bile acids in hepatobiliary injury - What is the link?

Fickert P, Wagner M.

J Hepatol. 2017 Sep;67(3):619-631. doi: 10.1016/j.jhep.2017.04.026. Epub 2017 Jul 14. Review.

PMID:
28712691
24.

Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice.

Durchschein F, Krones E, Pollheimer MJ, Zollner G, Wagner M, Raufman JP, Fickert P.

Hepatol Res. 2018 Feb;48(3):E68-E77. doi: 10.1111/hepr.12928. Epub 2017 Aug 26.

PMID:
28635176
25.

Life-threatening sinusoidal obstruction syndrome after high-dose chemotherapy linked to compound heterozygous mutations in ABCB11.

Stampfer L, Sperl D, Fickert P, Lackner H, Sovinz P, Ofner-Ziegenfuß L, Strenger V, Urban C, Jahnel J, Seidel MG.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26666. Epub 2017 Jun 9. No abstract available.

PMID:
28598581
26.

norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.

Fickert P, Hirschfield GM, Denk G, Marschall HU, Altorjay I, Färkkilä M, Schramm C, Spengler U, Chapman R, Bergquist A, Schrumpf E, Nevens F, Trivedi P, Reiter FP, Tornai I, Halilbasic E, Greinwald R, Pröls M, Manns MP, Trauner M; European PSC norUDCA Study Group.

J Hepatol. 2017 Sep;67(3):549-558. doi: 10.1016/j.jhep.2017.05.009. Epub 2017 May 18.

27.

Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline.

Aabakken L, Karlsen TH, Albert J, Arvanitakis M, Chazouilleres O, Dumonceau JM, Färkkilä M, Fickert P, Hirschfield GM, Laghi A, Marzioni M, Fernandez M, Pereira SP, Pohl J, Poley JW, Ponsioen CY, Schramm C, Swahn F, Tringali A, Hassan C.

Endoscopy. 2017 Jun;49(6):588-608. doi: 10.1055/s-0043-107029. Epub 2017 Apr 18.

28.

NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.

Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, Fickert P.

J Hepatol. 2017 Jul;67(1):110-119. doi: 10.1016/j.jhep.2017.02.019. Epub 2017 Feb 27.

PMID:
28242240
29.

Bad memories from the gut may cause nightmares for the bile ducts.

Fickert P.

J Hepatol. 2017 Jan;66(1):5-7. doi: 10.1016/j.jhep.2016.09.016. Epub 2016 Oct 1. No abstract available.

PMID:
27702642
30.

Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis.

Horvath A, Leber B, Schmerboeck B, Tawdrous M, Zettel G, Hartl A, Madl T, Stryeck S, Fuchs D, Lemesch S, Douschan P, Krones E, Spindelboeck W, Durchschein F, Rainer F, Zollner G, Stauber RE, Fickert P, Stiegler P, Stadlbauer V.

Aliment Pharmacol Ther. 2016 Nov;44(9):926-935. doi: 10.1111/apt.13788. Epub 2016 Sep 4.

31.

Indications for liver transplantation in adults : Recommendations of the Austrian Society for Gastroenterology and Hepatology (ÖGGH) in cooperation with the Austrian Society for Transplantation, Transfusion and Genetics (ATX).

Graziadei I, Zoller H, Fickert P, Schneeberger S, Finkenstedt A, Peck-Radosavljevic M, Müller H, Kohl C, Sperner-Unterweger B, Eschertzhuber S, Hofer H, Öfner D, Tilg H, Vogel W, Trauner M, Berlakovich G.

Wien Klin Wochenschr. 2016 Oct;128(19-20):679-690. Epub 2016 Sep 2.

32.

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.

Grumet L, Eichmann TO, Taschler U, Zierler KA, Leopold C, Moustafa T, Radovic B, Romauch M, Yan C, Du H, Haemmerle G, Zechner R, Fickert P, Kratky D, Zimmermann R, Lass A.

J Biol Chem. 2016 Aug 19;291(34):17977-87. doi: 10.1074/jbc.M116.724054. Epub 2016 Jun 27.

33.

Secretin and cholestasis, two sides of a coin.

Wagner M, Fickert P, Zollner G.

Hepatology. 2016 Sep;64(3):714-6. doi: 10.1002/hep.28687. Epub 2016 Jul 29. No abstract available.

PMID:
27312229
34.

Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.

Tang Y, Fickert P, Trauner M, Marcus N, Blomenkamp K, Teckman J.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G156-65. doi: 10.1152/ajpgi.00143.2015. Epub 2016 Apr 21.

35.

Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.

Reiter FP, Wimmer R, Wottke L, Artmann R, Nagel JM, Carranza MO, Mayr D, Rust C, Fickert P, Trauner M, Gerbes AL, Hohenester S, Denk GU.

World J Hepatol. 2016 Mar 18;8(8):401-10. doi: 10.4254/wjh.v8.i8.401.

36.

The chronic kidney disease epidemiology collaboration equation combining creatinine and cystatin C accurately assesses renal function in patients with cirrhosis.

Krones E, Fickert P, Zitta S, Neunherz S, Artinger K, Reibnegger G, Durchschein F, Wagner D, Stojakovic T, Stadlbauer V, Fauler G, Stauber R, Zollner G, Kniepeiss D, Rosenkranz AR.

BMC Nephrol. 2015 Dec 1;16:196. doi: 10.1186/s12882-015-0188-0.

37.

Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.

Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M.

J Hepatol. 2016 Mar;64(3):674-81. doi: 10.1016/j.jhep.2015.10.024. Epub 2015 Oct 31.

38.

Lactobacillus casei Shirota Supplementation Does Not Restore Gut Microbiota Composition and Gut Barrier in Metabolic Syndrome: A Randomized Pilot Study.

Stadlbauer V, Leber B, Lemesch S, Trajanoski S, Bashir M, Horvath A, Tawdrous M, Stojakovic T, Fauler G, Fickert P, Högenauer C, Klymiuk I, Stiegler P, Lamprecht M, Pieber TR, Tripolt NJ, Sourij H.

PLoS One. 2015 Oct 28;10(10):e0141399. doi: 10.1371/journal.pone.0141399. eCollection 2015.

39.

Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.

Chen Y, Guldiken N, Spurny M, Mohammed HH, Haybaeck J, Pollheimer MJ, Fickert P, Gassler N, Jeon MK, Trautwein C, Strnad P.

J Pathol. 2015 Nov;237(3):343-54. doi: 10.1002/path.4580. Epub 2015 Aug 3.

PMID:
26108453
40.

Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.

Trauner M, Halilbasic E, Claudel T, Steinacher D, Fuchs C, Moustafa T, Pollheimer M, Krones E, Kienbacher C, Traussnigg S, Kazemi-Shirazi L, Munda P, Hofer H, Fickert P, Paumgartner G.

Dig Dis. 2015;33(3):433-9. doi: 10.1159/000371904. Epub 2015 May 27. Review.

PMID:
26045280
41.

Bile acid-induced cholemic nephropathy.

Krones E, Wagner M, Eller K, Rosenkranz AR, Trauner M, Fickert P.

Dig Dis. 2015;33(3):367-75. doi: 10.1159/000371689. Epub 2015 May 27. Review.

PMID:
26045271
42.

Reply.

Krones E, Erwa W, Trauner M, Fickert P.

Hepatology. 2016 Jan;63(1):346-7. doi: 10.1002/hep.27873. Epub 2015 Jun 19. No abstract available.

PMID:
25929841
43.

Emergency Double-Stenting and Surgery for the Successful Management of Massive Upper Gastrointestinal Bleeding Caused by Mycotic Aortic Aneurysm.

Hackl G, Portugaller RH, Fickert P.

Clin Gastroenterol Hepatol. 2015 Dec;13(13):e171-2. doi: 10.1016/j.cgh.2015.04.016. Epub 2015 Apr 23. No abstract available.

PMID:
25912836
44.

Clinical-pathological conference series from the Medical University of Graz: case no. 151: 19-year-old student from Albania with emergency admission due to shock.

Fabian E, Madl C, Horn S, Kornprat P, Maderthaner R, Aigelsreiter A, Krause R, Fickert P, Krejs GJ.

Wien Klin Wochenschr. 2015 Feb;127(3-4):151-9. doi: 10.1007/s00508-014-0636-z. Epub 2014 Dec 4. No abstract available.

PMID:
25471000
45.

24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis.

Sombetzki M, Fuchs CD, Fickert P, Österreicher CH, Mueller M, Claudel T, Loebermann M, Engelmann R, Langner C, Sahin E, Schwinge D, Guenther ND, Schramm C, Mueller-Hilke B, Reisinger EC, Trauner M.

J Hepatol. 2015 Apr;62(4):871-8. doi: 10.1016/j.jhep.2014.11.020. Epub 2014 Nov 21.

46.

Serum alkaline phosphatase levels accurately reflect cholestasis in mice.

Krones E, Erwa W, Trauner M, Fickert P.

Hepatology. 2015 Sep;62(3):981-3. doi: 10.1002/hep.27622. Epub 2015 Jun 19. No abstract available.

PMID:
25424394
47.

Alterations of canalicular ATP-binding cassette transporter expression in drug-induced liver injury.

Zollner G, Thueringer A, Lackner C, Fickert P, Trauner M.

Digestion. 2014;90(2):81-8. doi: 10.1159/000365003. Epub 2014 Sep 4.

PMID:
25196354
48.

Vitamin D modulates biliary fibrosis in ABCB4-deficient mice.

Hochrath K, Stokes CS, Geisel J, Pollheimer MJ, Fickert P, Dooley S, Lammert F.

Hepatol Int. 2014 Jun 21;8(3):443-52. doi: 10.1007/s12072-014-9548-2. eCollection 2014 Jul.

49.

Animal models in primary biliary cirrhosis and primary sclerosing cholangitis.

Pollheimer MJ, Fickert P.

Clin Rev Allergy Immunol. 2015 Jun;48(2-3):207-17. doi: 10.1007/s12016-014-8442-y. Review.

PMID:
25172178
50.

Inflammatory bowel disease alters intestinal bile acid transporter expression.

Jahnel J, Fickert P, Hauer AC, Högenauer C, Avian A, Trauner M.

Drug Metab Dispos. 2014 Sep;42(9):1423-31. doi: 10.1124/dmd.114.058065. Epub 2014 Jun 25.

PMID:
24965812

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