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Items: 1 to 50 of 65

1.

Assessment of branch point prediction tools to predict physiological branch points and their alteration by variants.

Leman R, Tubeuf H, Raad S, Tournier I, Derambure C, Lanos R, Gaildrat P, Castelain G, Hauchard J, Killian A, Baert-Desurmont S, Legros A, Goardon N, Quesnelle C, Ricou A, Castera L, Vaur D, Le Gac G, Ka C, Fichou Y, Bonnet-Dorion F, Sevenet N, Guillaud-Bataille M, Boutry-Kryza N, Schultz I, Caux-Moncoutier V, Rossing M, Walker LC, Spurdle AB, Houdayer C, Martins A, Krieger S.

BMC Genomics. 2020 Jan 28;21(1):86. doi: 10.1186/s12864-020-6484-5.

2.

Electrostatically Driven Complex Coacervation and Amyloid Aggregation of Tau Are Independent Processes with Overlapping Conditions.

Lin Y, Fichou Y, Zeng Z, Hu NY, Han S.

ACS Chem Neurosci. 2020 Feb 4. doi: 10.1021/acschemneuro.9b00627. [Epub ahead of print]

PMID:
31971365
3.

Tau-Cofactor Complexes as Building Blocks of Tau Fibrils.

Fichou Y, Oberholtzer ZR, Ngo H, Cheng CY, Keller TJ, Eschmann NA, Han S.

Front Neurosci. 2019 Dec 13;13:1339. doi: 10.3389/fnins.2019.01339. eCollection 2019.

4.

Novel diagnostic tool for prediction of variant spliceogenicity derived from a set of 395 combined in silico/in vitro studies: an international collaborative effort.

Leman R, Gaildrat P, Le Gac G, Ka C, Fichou Y, Audrezet MP, Caux-Moncoutier V, Caputo SM, Boutry-Kryza N, Léone M, Mazoyer S, Bonnet-Dorion F, Sevenet N, Guillaud-Bataille M, Rouleau E, Bressac-de Paillerets B, Wappenschmidt B, Rossing M, Muller D, Bourdon V, Revillon F, Parsons MT, Rousselin A, Davy G, Castelain G, Castéra L, Sokolowska J, Coulet F, Delnatte C, Férec C, Spurdle AB, Martins A, Krieger S, Houdayer C.

Nucleic Acids Res. 2019 Dec 21. pii: gkz1212. doi: 10.1093/nar/gkz1212. [Epub ahead of print] No abstract available.

PMID:
31863589
5.

First estimate of the scale of canonical 5' splice site GT>GC variants capable of generating wild-type transcripts.

Lin JH, Tang XY, Boulling A, Zou WB, Masson E, Fichou Y, Raud L, Le Tertre M, Deng SJ, Berlivet I, Ka C, Mort M, Hayden M, Leman R, Houdayer C, Le Gac G, Cooper DN, Li ZS, Férec C, Liao Z, Chen JM.

Hum Mutat. 2019 Oct;40(10):1856-1873. doi: 10.1002/humu.23821. Epub 2019 Jun 24.

PMID:
31131953
6.

Publisher Correction: Tauopathies: Protein shapes at the core of chronic traumatic encephalopathy.

Fichou Y, Han S.

Nat Struct Mol Biol. 2019 Jun;26(6):526. doi: 10.1038/s41594-019-0251-9.

PMID:
31123350
7.

Protein shapes at the core of chronic traumatic encephalopathy.

Fichou Y, Han S.

Nat Struct Mol Biol. 2019 May;26(5):336-338. doi: 10.1038/s41594-019-0221-2. No abstract available. Erratum in: Nat Struct Mol Biol. 2019 Jun;26(6):526.

PMID:
31011211
8.

A novel JK null allele in a Brazilian patient with sickle cell disease (SCD).

Castilho L, Bub CB, Aravechia MG, Kutner JM, Berlivet I, Férec C, Fichou Y.

Transfusion. 2019 Jul;59(7):2459-2460. doi: 10.1111/trf.15304. Epub 2019 Apr 9. No abstract available.

PMID:
30964549
9.

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

Fichou Y, Al-Hilaly YK, Devred F, Smet-Nocca C, Tsvetkov PO, Verelst J, Winderickx J, Geukens N, Vanmechelen E, Perrotin A, Serpell L, Hanseeuw BJ, Medina M, Buée L, Landrieu I.

Acta Neuropathol Commun. 2019 Mar 1;7(1):31. doi: 10.1186/s40478-019-0682-x. Review.

10.

Functional analysis of novel RHD variants: splicing disruption is likely to be a common mechanism of variant D phenotype.

Raud L, Ka C, Gourlaouen I, Callebaut I, Férec C, Le Gac G, Fichou Y.

Transfusion. 2019 Apr;59(4):1367-1375. doi: 10.1111/trf.15210. Epub 2019 Feb 27.

PMID:
30811032
11.

Cofactors are essential constituents of stable and seeding-active tau fibrils.

Fichou Y, Lin Y, Rauch JN, Vigers M, Zeng Z, Srivastava M, Keller TJ, Freed JH, Kosik KS, Han S.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13234-13239. doi: 10.1073/pnas.1810058115. Epub 2018 Dec 11.

12.

Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.

El Housse H, El Wafi M, Ouabdelmoumene Z, Zarati F, Alid R, Nourichafi N, Bouisk K, Benajiba M, Férec C, Fichou Y, Habti N.

Blood Transfus. 2019 Mar;17(2):151-156. doi: 10.2450/2018.0153-18. Epub 2018 Oct 24.

13.

Corrigendum: Novel diagnostic tool for prediction of variant spliceogenicity derived from a set of 395 combined in silico/in vitro studies: an international collaborative effort.

Leman R, Gaildrat P, Gac GL, Ka C, Fichou Y, Audrezet MP, Caux-Moncoutier V, Caputo SM, Boutry-Kryza N, Léone M, Mazoyer S, Bonnet-Dorion F, Sevenet N, Guillaud-Bataille M, Rouleau E, Paillerets BB, Wappenschmidt B, Rossing M, Muller D, Bourdon V, Revillon F, Parsons MT, Rousselin A, Davy G, Castelain G, Castéra L, Sokolowska J, Coulet F, Delnatte C, Férec C, Spurdle AB, Martins A, Krieger S, Houdayer C.

Nucleic Acids Res. 2018 Nov 30;46(21):11656-11657. doi: 10.1093/nar/gky979. No abstract available.

14.

Estimating the age of p.(Phe508del) with family studies of geographically distinct European populations and the early spread of cystic fibrosis.

Farrell P, Férec C, Macek M, Frischer T, Renner S, Riss K, Barton D, Repetto T, Tzetis M, Giteau K, Duno M, Rogers M, Levy H, Sahbatou M, Fichou Y, Le Maréchal C, Génin E.

Eur J Hum Genet. 2018 Dec;26(12):1832-1839. doi: 10.1038/s41431-018-0234-z. Epub 2018 Aug 8.

15.

Correction: Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments.

Fichou Y, Vigers M, Goring AK, Eschmann NA, Han S.

Chem Commun (Camb). 2018 Aug 11;54(62):8653. doi: 10.1039/c8cc90325e. Epub 2018 Jul 20.

PMID:
30027190
16.

RHD-Positive Alleles among D- C/E+ Individuals from India.

Kulkarni SS, Gogri H, Parchure D, Mishra G, Ghosh K, Rajadhyaksha S, Madkaikar M, Férec C, Fichou Y.

Transfus Med Hemother. 2018 May;45(3):173-177. doi: 10.1159/000479239. Epub 2018 Jan 10.

17.

Novel diagnostic tool for prediction of variant spliceogenicity derived from a set of 395 combined in silico/in vitro studies: an international collaborative effort.

Leman R, Gaildrat P, Le Gac G, Ka C, Fichou Y, Audrezet MP, Caux-Moncoutier V, Caputo SM, Boutry-Kryza N, Léone M, Mazoyer S, Bonnet-Dorion F, Sevenet N, Guillaud-Bataille M, Rouleau E, Bressac-de Paillerets B, Wappenschmidt B, Rossing M, Muller D, Bourdon V, Revillon F, Parsons MT, Rousselin A, Davy G, Castelain G, Castéra L, Sokolowska J, Coulet F, Delnatte C, Férec C, Spurdle AB, Martins A, Krieger S, Houdayer C.

Nucleic Acids Res. 2018 Sep 6;46(15):7913-7923. doi: 10.1093/nar/gky372. Erratum in: Nucleic Acids Res. 2018 Nov 30;46(21):11656-11657.

18.

Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments.

Fichou Y, Vigers M, Goring AK, Eschmann NA, Han S.

Chem Commun (Camb). 2018 May 1;54(36):4573-4576. doi: 10.1039/c8cc01355a. Erratum in: Chem Commun (Camb). 2018 Aug 11;54(62):8653.

PMID:
29664486
19.

Molecular basis of weak D expression in the Indian population and report of a novel, predominant variant RHD allele.

Fichou Y, Parchure D, Gogri H, Gopalkrishnan V, Le Maréchal C, Chen JM, Férec C, Madkaikar M, Ghosh K, Kulkarni S.

Transfusion. 2018 Jun;58(6):1540-1549. doi: 10.1111/trf.14552. Epub 2018 Feb 25.

PMID:
29479713
20.

Weak D type 1, 2 and 3 subtype alleles are rare in the Western French population.

Raud L, Le Maréchal C, Férec C, Fichou Y.

Transfus Med. 2019 Jun;29(3):209-210. doi: 10.1111/tme.12485. Epub 2017 Nov 22. No abstract available.

PMID:
29168247
21.

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium.

Barnes R, Sun S, Fichou Y, Dahlquist FW, Heyden M, Han S.

J Am Chem Soc. 2017 Dec 13;139(49):17890-17901. doi: 10.1021/jacs.7b08606. Epub 2017 Nov 27.

22.

Conformation-based assay of tau protein aggregation.

Fichou Y, Eschmann NA, Keller TJ, Han S.

Methods Cell Biol. 2017;141:89-112. doi: 10.1016/bs.mcb.2017.06.008. Epub 2017 Aug 10.

PMID:
28882313
23.

From genetic variability to phenotypic expression of blood group systems.

Raud L, Férec C, Fichou Y.

Transfus Clin Biol. 2017 Nov;24(4):472-475. doi: 10.1016/j.tracli.2017.06.011. Epub 2017 Jun 29. Review.

PMID:
28669524
24.

NGS and blood group systems: State of the art and perspectives.

Fichou Y, Férec C.

Transfus Clin Biol. 2017 Sep;24(3):240-244. doi: 10.1016/j.tracli.2017.06.002. Epub 2017 Jun 21. Review.

PMID:
28645642
25.

First report of Rhnull individuals in the Indian population and characterization of the underlying molecular mechanisms.

Kulkarni SS, Vasantha K, Gogri H, Parchure D, Madkaikar M, Férec C, Fichou Y.

Transfusion. 2017 Aug;57(8):1944-1948. doi: 10.1111/trf.14150. Epub 2017 May 3.

PMID:
28470789
26.

A ring-shaped conduit connects the mother cell and forespore during sporulation in Bacillus subtilis.

Rodrigues CD, Henry X, Neumann E, Kurauskas V, Bellard L, Fichou Y, Schanda P, Schoehn G, Rudner DZ, Morlot C.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11585-11590. Epub 2016 Sep 28.

27.

Neutrons describe ectoine effects on water H-bonding and hydration around a soluble protein and a cell membrane.

Zaccai G, Bagyan I, Combet J, Cuello GJ, Demé B, Fichou Y, Gallat FX, Galvan Josa VM, von Gronau S, Haertlein M, Martel A, Moulin M, Neumann M, Weik M, Oesterhelt D.

Sci Rep. 2016 Aug 16;6:31434. doi: 10.1038/srep31434.

28.

The experience of extended blood group genotyping by next-generation sequencing (NGS): investigation of patients with sickle-cell disease.

Fichou Y, Mariez M, Le Maréchal C, Férec C.

Vox Sang. 2016 Nov;111(4):418-424. doi: 10.1111/vox.12432. Epub 2016 Jul 21.

PMID:
27442304
29.

No Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations.

Zou WB, Boulling A, Masamune A, Issarapu P, Masson E, Wu H, Sun XT, Hu LH, Zhou DZ, He L, Fichou Y, Nakano E, Hamada S, Kakuta Y, Kume K, Isayama H, Paliwal S, Mani KR, Bhaskar S, Cooper DN, Férec C, Shimosegawa T, Chandak GR, Chen JM, Li ZS, Liao Z.

Gastroenterology. 2016 Jun;150(7):1558-1560.e5. doi: 10.1053/j.gastro.2016.02.071. Epub 2016 Mar 3.

30.

Identification of novel variant A alleles within the ABO gene.

Fichou Y, Hennion M, Dupont I, Jamet D, Le Maréchal C, Férec C.

Transfusion. 2016 May;56(5):1244-6. doi: 10.1111/trf.13542. Epub 2016 Feb 26. No abstract available.

PMID:
26920498
31.

Insights into RHCE Molecular Analysis in Samples with Partial D Variants: the Experience of Western France.

Fichou Y, Le Maréchal C, Scotet V, Jamet D, Férec C.

Transfus Med Hemother. 2015 Nov;42(6):372-7. doi: 10.1159/000382086. Epub 2015 Jul 23.

32.

Molecular Dynamics Simulations of a Powder Model of the Intrinsically Disordered Protein Tau.

Fichou Y, Heyden M, Zaccai G, Weik M, Tobias DJ.

J Phys Chem B. 2015 Oct 1;119(39):12580-9. doi: 10.1021/acs.jpcb.5b05849. Epub 2015 Sep 18.

PMID:
26351734
33.

Molecular RHD-RHCE Analysis by Multiplex PCR of Short Fluorescent Fragments.

Fichou Y, Férec C.

Methods Mol Biol. 2015;1310:97-104. doi: 10.1007/978-1-4939-2690-9_8.

PMID:
26024628
34.

Hydration water mobility is enhanced around tau amyloid fibers.

Fichou Y, Schirò G, Gallat FX, Laguri C, Moulin M, Combet J, Zamponi M, Härtlein M, Picart C, Mossou E, Lortat-Jacob H, Colletier JP, Tobias DJ, Weik M.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6365-70. doi: 10.1073/pnas.1422824112. Epub 2015 Apr 27.

35.

Extensive functional analyses of RHD splice site variants: Insights into the potential role of splicing in the physiology of Rh.

Fichou Y, Gehannin P, Corre M, Le Guern A, Le Maréchal C, Le Gac G, Férec C.

Transfusion. 2015 Jun;55(6 Pt 2):1432-43. doi: 10.1111/trf.13083. Epub 2015 Mar 21.

PMID:
25808592
36.

Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins.

Schirò G, Fichou Y, Gallat FX, Wood K, Gabel F, Moulin M, Härtlein M, Heyden M, Colletier JP, Orecchini A, Paciaroni A, Wuttke J, Tobias DJ, Weik M.

Nat Commun. 2015 Mar 16;6:6490. doi: 10.1038/ncomms7490.

37.

Next-generation sequencing is a credible strategy for blood group genotyping.

Fichou Y, Audrézet MP, Guéguen P, Le Maréchal C, Férec C.

Br J Haematol. 2014 Nov;167(4):554-62. doi: 10.1111/bjh.13084. Epub 2014 Aug 19.

PMID:
25135605
38.

Distribution of Rhesus blood group antigens and weak D alleles in the population of Albania.

Xhetani M, Seferi I, Férec C, Zoraqi G, Fichou Y.

Blood Transfus. 2014 Oct;12(4):565-9. doi: 10.2450/2014.0240-13. Epub 2014 Jun 12.

39.

The RHD*weak D type 4.0 allele is predominantly but not exclusively cis-associated with the altered RHCE*ce(c.48C, c.105T, c.733G, c.744C, c.1025T) allele in the French population.

Fichou Y, Maréchal CL, Férec C.

Transfus Med. 2014 Apr;24(2):120-2. doi: 10.1111/tme.12100. Epub 2014 Jan 24. No abstract available.

PMID:
24456293
40.

A missense mutation in the alpha-actinin 1 gene (ACTN1) is the cause of autosomal dominant macrothrombocytopenia in a large French family.

Guéguen P, Rouault K, Chen JM, Raguénès O, Fichou Y, Hardy E, Gobin E, Pan-Petesch B, Kerbiriou M, Trouvé P, Marcorelles P, Abgrall JF, Le Maréchal C, Férec C.

PLoS One. 2013 Sep 17;8(9):e74728. doi: 10.1371/journal.pone.0074728. eCollection 2013.

41.

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.

Fichou Y, Le Maréchal C, Bryckaert L, Dupont I, Jamet D, Chen JM, Férec C.

Transfusion. 2013 Nov;53(11 Suppl 2):2974-82. doi: 10.1111/trf.12179. Epub 2013 Apr 3.

PMID:
23550903
42.

Establishment of a medium-throughput approach for the genotyping of RHD variants and report of nine novel rare alleles.

Fichou Y, Le Maréchal C, Jamet D, Bryckaert L, Ka C, Audrézet MP, Le Gac G, Dupont I, Chen JM, Férec C.

Transfusion. 2013 Aug;53(8):1821-8. doi: 10.1111/trf.12009. Epub 2012 Dec 11.

PMID:
23228153
43.

A polymer surfactant corona dynamically replaces water in solvent-free protein liquids and ensures macromolecular flexibility and activity.

Gallat FX, Brogan AP, Fichou Y, McGrath N, Moulin M, Härtlein M, Combet J, Wuttke J, Mann S, Zaccai G, Jackson CJ, Perriman AW, Weik M.

J Am Chem Soc. 2012 Aug 15;134(32):13168-71. doi: 10.1021/ja303894g. Epub 2012 Aug 2.

PMID:
22853639
44.

Small deletions within the RHD coding sequence: a report of two novel mutational events and a survey of the underlying pathophysiologic mechanisms.

Chen JM, Fichou Y, Jamet D, Dupont I, Cooper DN, Le Maréchal C, Férec C.

Transfusion. 2013 Jan;53(1):206-10. doi: 10.1111/j.1537-2995.2012.03713.x. Epub 2012 May 21.

PMID:
22612274
45.

Weak D caused by a founder deletion in the RHD gene.

Fichou Y, Chen JM, Le Maréchal C, Jamet D, Dupont I, Chuteau C, Durousseau C, Loirat MJ, Bailly P, Férec C.

Transfusion. 2012 Nov;52(11):2348-55. doi: 10.1111/j.1537-2995.2012.03606.x. Epub 2012 Mar 15.

PMID:
22420867
46.

Variant screening of the RHD gene in a large cohort of subjects with D phenotype ambiguity: report of 17 novel rare alleles.

Fichou Y, Le Maréchal C, Bryckaert L, Guerry C, Bénech C, Dupont I, Jamet D, Férec C, Chen JM.

Transfusion. 2012 Apr;52(4):759-64. doi: 10.1111/j.1537-2995.2011.03350.x. Epub 2011 Sep 26. Erratum in: Transfusion. 2012 Aug;52(8):1842.

PMID:
21950494
47.

Synthesis and characterization of core∕shell Fe(3)O(4)∕ZnSe fluorescent magnetic nanoparticles.

Vargas JM, McBride AA, Plumley JB, Fichou Y, Memon TA, Shah V, Cook NC, Akins BA, Rivera AC, Smolyakov GA, O'Brien JR, Adolphi NL, Smyth HD, Osiński M.

J Appl Phys. 2011 Apr 1;109(7):7B536-7B5363. Epub 2011 Apr 8.

48.

A missense mutation within the fork-head domain of the forkhead box G1 Gene (FOXG1) affects its nuclear localization.

Le Guen T, Fichou Y, Nectoux J, Bahi-Buisson N, Rivier F, Boddaert N, Diebold B, Héron D, Chelly J, Bienvenu T.

Hum Mutat. 2011 Feb;32(2):E2026-35. doi: 10.1002/humu.21422. Epub 2010 Dec 7.

PMID:
21280142
49.

An isoform of the severe encephalopathy-related CDKL5 gene, including a novel exon with extremely high sequence conservation, is specifically expressed in brain.

Fichou Y, Nectoux J, Bahi-Buisson N, Chelly J, Bienvenu T.

J Hum Genet. 2011 Jan;56(1):52-7. doi: 10.1038/jhg.2010.143. Epub 2010 Dec 2.

PMID:
21124335
50.

Cell cloning-based transcriptome analysis in cyclin-dependent kinase-like 5 mutation patients with severe epileptic encephalopathy.

Nectoux J, Fichou Y, Cagnard N, Bahi-Buisson N, Nusbaum P, Letourneur F, Chelly J, Bienvenu T.

J Mol Med (Berl). 2011 Feb;89(2):193-202. doi: 10.1007/s00109-010-0699-x. Epub 2010 Nov 24.

PMID:
21107515

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