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Items: 14


A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation.

Park HJ, Mylvaganum M, McPherson A, Fewell SW, Brodsky JL, Lingwood CA.

Chem Biol. 2009 Apr 24;16(4):461-70. doi: 10.1016/j.chembiol.2009.02.014.


Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.

Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL.

Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4.


Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.

Patham B, Duffy J, Lane A, Davis RC, Wipf P, Fewell SW, Brodsky JL, Mensa-Wilmot K.

Biochem J. 2009 Apr 15;419(2):507-17. doi: 10.1042/BJ20081787.


Design of a fluorescence polarization assay platform for the study of human Hsp70.

Kang Y, Taldone T, Clement CC, Fewell SW, Aguirre J, Brodsky JL, Chiosis G.

Bioorg Med Chem Lett. 2008 Jul 1;18(13):3749-51. doi: 10.1016/j.bmcl.2008.05.046. Epub 2008 May 16.


The Hsp40 molecular chaperone Ydj1p, along with the protein kinase C pathway, affects cell-wall integrity in the yeast Saccharomyces cerevisiae.

Wright CM, Fewell SW, Sullivan ML, Pipas JM, Watkins SC, Brodsky JL.

Genetics. 2007 Apr;175(4):1649-64. Epub 2007 Jan 21.


Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.

Fewell SW, Smith CM, Lyon MA, Dumitrescu TP, Wipf P, Day BW, Brodsky JL.

J Biol Chem. 2004 Dec 3;279(49):51131-40. Epub 2004 Sep 23.


Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation.

Palmer EA, Kruse KB, Fewell SW, Buchanan SM, Brodsky JL, McCracken AA.

J Cell Sci. 2003 Jun 1;116(Pt 11):2361-73. Epub 2003 Apr 23.


The action of molecular chaperones in the early secretory pathway.

Fewell SW, Travers KJ, Weissman JS, Brodsky JL.

Annu Rev Genet. 2001;35:149-91. Review.


Identification of an inhibitor of hsc70-mediated protein translocation and ATP hydrolysis.

Fewell SW, Day BW, Brodsky JL.

J Biol Chem. 2001 Jan 12;276(2):910-4.


Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40.

Sullivan CS, Tremblay JD, Fewell SW, Lewis JA, Brodsky JL, Pipas JM.

Mol Cell Biol. 2000 Aug;20(15):5749-57.

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