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Items: 34

1.

Transcriptional Activation of Pericentromeric Satellite Repeats and Disruption of Centromeric Clustering upon Proteasome Inhibition.

Natisvili T, Yandim C, Silva R, Emanuelli G, Krueger F, Nageshwaran S, Festenstein R.

PLoS One. 2016 Nov 2;11(11):e0165873. doi: 10.1371/journal.pone.0165873. eCollection 2016.

2.

Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach.

Tam KT, Chan PK, Zhang W, Law PP, Tian Z, Fung Chan GC, Philipsen S, Festenstein R, Tan-Un KC.

Nucleic Acids Res. 2017 Jan 9;45(1):115-126. doi: 10.1093/nar/gkw820. Epub 2016 Sep 19.

3.

Epigenetics and Triplet-Repeat Neurological Diseases.

Nageshwaran S, Festenstein R.

Front Neurol. 2015 Dec 21;6:262. doi: 10.3389/fneur.2015.00262. eCollection 2015. Review.

4.

Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis.

Nashun B, Hill PW, Smallwood SA, Dharmalingam G, Amouroux R, Clark SJ, Sharma V, Ndjetehe E, Pelczar P, Festenstein RJ, Kelsey G, Hajkova P.

Mol Cell. 2015 Nov 19;60(4):611-25. doi: 10.1016/j.molcel.2015.10.010. Epub 2015 Nov 5.

5.

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study.

Libri V, Yandim C, Athanasopoulos S, Loyse N, Natisvili T, Law PP, Chan PK, Mohammad T, Mauri M, Tam KT, Leiper J, Piper S, Ramesh A, Parkinson MH, Huson L, Giunti P, Festenstein R.

Lancet. 2014 Aug 9;384(9942):504-13. doi: 10.1016/S0140-6736(14)60382-2. Epub 2014 Apr 30.

6.
7.

Gene regulation and epigenetics in Friedreich's ataxia.

Yandim C, Natisvili T, Festenstein R.

J Neurochem. 2013 Aug;126 Suppl 1:21-42. doi: 10.1111/jnc.12254. Review.

8.

Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3.

Chan PK, Torres R, Yandim C, Law PP, Khadayate S, Mauri M, Grosan C, Chapman-Rothe N, Giunti P, Pook M, Festenstein R.

Hum Mol Genet. 2013 Jul 1;22(13):2662-75. doi: 10.1093/hmg/ddt115. Epub 2013 Mar 7.

PMID:
23474817
9.

Transcription elongation and tissue-specific somatic CAG instability.

Goula AV, Stys A, Chan JP, Trottier Y, Festenstein R, Merienne K.

PLoS Genet. 2012;8(11):e1003051. doi: 10.1371/journal.pgen.1003051. Epub 2012 Nov 29.

10.

Context is everything: activators can also repress.

Festenstein R, Chan JP.

Nat Struct Mol Biol. 2012 Oct;19(10):973-5. doi: 10.1038/nsmb.2401.

PMID:
23037592
11.

H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation.

Guillemette B, Drogaris P, Lin HH, Armstrong H, Hiragami-Hamada K, Imhof A, Bonneil E, Thibault P, Verreault A, Festenstein RJ.

PLoS Genet. 2011 Mar;7(3):e1001354. doi: 10.1371/journal.pgen.1001354. Epub 2011 Mar 31.

12.

Epigenetic regulation of autosomal gene expression by sex chromosomes.

Wijchers PJ, Festenstein RJ.

Trends Genet. 2011 Apr;27(4):132-40. doi: 10.1016/j.tig.2011.01.004. Epub 2011 Feb 18. Review.

PMID:
21334089
13.

Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice.

Bishop MW, Chakraborty S, Matthews GA, Dougalis A, Wood NW, Festenstein R, Ungless MA.

J Neurophysiol. 2010 Dec;104(6):3009-20. doi: 10.1152/jn.00466.2010. Epub 2010 Oct 6.

14.

Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromosome complement as well.

Wijchers PJ, Yandim C, Panousopoulou E, Ahmad M, Harker N, Saveliev A, Burgoyne PS, Festenstein R.

Dev Cell. 2010 Sep 14;19(3):477-84. doi: 10.1016/j.devcel.2010.08.005.

15.

The molecular basis for stability of heterochromatin-mediated silencing in mammals.

Hiragami-Hamada K, Xie SQ, Saveliev A, Uribe-Lewis S, Pombo A, Festenstein R.

Epigenetics Chromatin. 2009 Nov 4;2(1):14. doi: 10.1186/1756-8935-2-14.

16.

Breaking the silence in Friedreich's ataxia.

Festenstein R.

Nat Chem Biol. 2006 Oct;2(10):512-3. No abstract available.

PMID:
16983383
17.

The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus.

Manderson AP, Carlucci F, Lachmann PJ, Lazarus RA, Festenstein RJ, Cook HT, Walport MJ, Botto M.

Arthritis Res Ther. 2006;8(3):R68. Epub 2006 Apr 10.

18.

Epigenetic regulation: DNA confers identity but is not enough to maintain it.

Poot RA, Festenstein R.

Genome Biol. 2006;7(1):302. Epub 2006 Jan 27. No abstract available.

19.

Heterochromatin protein 1: a pervasive controlling influence.

Hiragami K, Festenstein R.

Cell Mol Life Sci. 2005 Dec;62(23):2711-26. Review.

PMID:
16261261
20.

Decoding the epigenetic effects of chromatin.

Festenstein R, Aragon L.

Genome Biol. 2003;4(10):342. Epub 2003 Sep 23.

21.

Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication.

Azuara V, Brown KE, Williams RR, Webb N, Dillon N, Festenstein R, Buckle V, Merkenschlager M, Fisher AG.

Nat Cell Biol. 2003 Jul;5(7):668-74.

PMID:
12833066
22.

DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing.

Saveliev A, Everett C, Sharpe T, Webster Z, Festenstein R.

Nature. 2003 Apr 24;422(6934):909-13.

PMID:
12712207
23.

Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells.

Festenstein R, Pagakis SN, Hiragami K, Lyon D, Verreault A, Sekkali B, Kioussis D.

Science. 2003 Jan 31;299(5607):719-21.

24.

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

Taniuchi I, Sunshine MJ, Festenstein R, Littman DR.

Mol Cell. 2002 Nov;10(5):1083-96.

25.

Unravelling heterochromatin: competition between positive and negative factors regulates accessibility.

Dillon N, Festenstein R.

Trends Genet. 2002 May;18(5):252-8. Review.

PMID:
12047950
26.

Locus control regions and epigenetic chromatin modifiers.

Festenstein R, Kioussis D.

Curr Opin Genet Dev. 2000 Apr;10(2):199-203. Review.

PMID:
10753778
27.

Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner.

Festenstein R, Sharghi-Namini S, Fox M, Roderick K, Tolaini M, Norton T, Saveliev A, Kioussis D, Singh P.

Nat Genet. 1999 Dec;23(4):457-61.

PMID:
10581035
28.

Human HMG box transcription factor HBP1: a role in hCD2 LCR function.

Zhuma T, Tyrrell R, Sekkali B, Skavdis G, Saveliev A, Tolaini M, Roderick K, Norton T, Smerdon S, Sedgwick S, Festenstein R, Kioussis D.

EMBO J. 1999 Nov 15;18(22):6396-406.

29.

Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals.

Kioussis D, Festenstein R.

Curr Opin Genet Dev. 1997 Oct;7(5):614-9. Review.

PMID:
9388777
30.

A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.

Hostert A, Tolaini M, Festenstein R, McNeill L, Malissen B, Williams O, Zamoyska R, Kioussis D.

J Immunol. 1997 May 1;158(9):4270-81.

PMID:
9126989
31.

Locus control region function and heterochromatin-induced position effect variegation.

Festenstein R, Tolaini M, Corbella P, Mamalaki C, Parrington J, Fox M, Miliou A, Jones M, Kioussis D.

Science. 1996 Feb 23;271(5252):1123-5.

PMID:
8599090
32.
33.

Transient amnesia heralding brain stem infarction.

Howard RS, Festenstein R, Mellers J, Kartsounis LD, Ron M.

J Neurol Neurosurg Psychiatry. 1992 Oct;55(10):977. No abstract available.

34.

Nimodipine in migraine prophylaxis.

Ansell E, Fazzone T, Festenstein R, Johnson ES, Thavapalan M, Wilkinson M, Wozniak I.

Cephalalgia. 1988 Dec;8(4):269-72.

PMID:
3064919

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