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Items: 39

1.

Predicting (side) effects for patients with inflammatory bowel disease: The promise of pharmacogenetics.

Voskuil MD, Bangma A, Weersma RK, Festen EAM.

World J Gastroenterol. 2019 Jun 7;25(21):2539-2548. doi: 10.3748/wjg.v25.i21.2539. Review.

2.

Reply to: Letter to the Editor: Single-cell RNA Sequencing of T Cells in Crohn's Disease (GASTRO-D-18-02454).

Uniken Venema WT, Voskuil MD, Festen EA.

Gastroenterology. 2019 May 28. pii: S0016-5085(19)40926-8. doi: 10.1053/j.gastro.2019.05.045. [Epub ahead of print] No abstract available.

PMID:
31150605
3.

Reply.

Uniken Venema WT, Voskuil MD, Festen EA.

Gastroenterology. 2019 May 28. pii: S0016-5085(19)40926-8. doi: 10.1053/j.gastro.2019.05.045. [Epub ahead of print] No abstract available.

PMID:
31150597
4.

Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn's Disease Exacerbations.

Klaassen MAY, Imhann F, Collij V, Fu J, Wijmenga C, Zhernakova A, Dijkstra G, Festen EAM, Gacesa R, Vich Vila A, Weersma RK.

J Crohns Colitis. 2019 Apr 10. pii: jjz077. doi: 10.1093/ecco-jcc/jjz077. [Epub ahead of print]

PMID:
31066440
5.

Correction to: The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1.

Imhann F, Van der Velde KJ, Barbieri R, Alberts R, Voskuil MD, Vila AV, Collij V, Spekhorst LM, Van der Sloot KWJ, Peters V, Van Dullemen HM, Visschedijk MC, Festen EAM, Swertz MA, Dijkstra G, Weersma RK.

BMC Gastroenterol. 2019 Mar 27;19(1):44. doi: 10.1186/s12876-019-0938-8.

6.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, Cole AT, Cummings FR, Daly MJ, Ellul P, Fedorak RN, Festen EAM, Florin TH, Gaya DR, Halfvarson J, Hart AL, Heerasing NM, Hendy P, Irving PM, Jones SE, Koskela J, Lindsay JO, Mansfield JC, McGovern D, Parkes M, Pollok RCG, Ramakrishnan S, Rampton DS, Rivas MA, Russell RK, Schultz M, Sebastian S, Seksik P, Singh A, So K, Sokol H, Subramaniam K, Todd A, Annese V, Weersma RK, Xavier R, Ward R, Weedon MN, Goodhand JR, Kennedy NA, Ahmad T; IBD Pharmacogenetics Study Group.

JAMA. 2019 Feb 26;321(8):773-785. doi: 10.1001/jama.2019.0709. Erratum in: JAMA. 2019 Apr 23;321(16):1636.

7.

SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects.

Collij V, Imhann F, Vich Vila A, Fu J, Dijkstra G, Festen EAM, Voskuil MD, Daly MJ, Xavier RJ, Wijmenga C, Zhernakova A, Weersma RK.

PLoS One. 2019 Jan 31;14(1):e0211328. doi: 10.1371/journal.pone.0211328. eCollection 2019.

8.

The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1.

Imhann F, Van der Velde KJ, Barbieri R, Alberts R, Voskuil MD, Vich Vila A, Collij V, Spekhorst LM, Van der Sloot KWJ, Peters V, Van Dullemen HM, Visschedijk MC, Festen EAM, Swertz MA, Dijkstra G, Weersma RK.

BMC Gastroenterol. 2019 Jan 8;19(1):5. doi: 10.1186/s12876-018-0917-5. Erratum in: BMC Gastroenterol. 2019 Mar 27;19(1):44.

9.

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome.

Vich Vila A, Imhann F, Collij V, Jankipersadsing SA, Gurry T, Mujagic Z, Kurilshikov A, Bonder MJ, Jiang X, Tigchelaar EF, Dekens J, Peters V, Voskuil MD, Visschedijk MC, van Dullemen HM, Keszthelyi D, Swertz MA, Franke L, Alberts R, Festen EAM, Dijkstra G, Masclee AAM, Hofker MH, Xavier RJ, Alm EJ, Fu J, Wijmenga C, Jonkers DMAE, Zhernakova A, Weersma RK.

Sci Transl Med. 2018 Dec 19;10(472). pii: eaap8914. doi: 10.1126/scitranslmed.aap8914.

PMID:
30567928
10.

Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-α biologicals and an Infliximab-biosimilar.

Buurman DJ, Blokzijl T, Festen EAM, Pham BT, Faber KN, Brouwer E, Dijkstra G.

PLoS One. 2018 Dec 11;13(12):e0208922. doi: 10.1371/journal.pone.0208922. eCollection 2018.

11.

Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.

Uniken Venema WT, Voskuil MD, Vila AV, van der Vries G, Jansen BH, Jabri B, Faber KN, Dijkstra G, Xavier RJ, Wijmenga C, Graham DB, Weersma RK, Festen EA.

Gastroenterology. 2019 Feb;156(3):812-815.e22. doi: 10.1053/j.gastro.2018.10.046. Epub 2018 Nov 2. No abstract available.

12.

MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians.

van der Velde KJ, Imhann F, Charbon B, Pang C, van Enckevort D, Slofstra M, Barbieri R, Alberts R, Hendriksen D, Kelpin F, de Haan M, de Boer T, Haakma S, Stroomberg C, Scholtens S, van de Geijn GJ, Festen EAM, Weersma RK, Swertz MA.

Bioinformatics. 2019 Mar 15;35(6):1076-1078. doi: 10.1093/bioinformatics/bty742.

13.

Sex-Related Differences in Patients With Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies.

Severs M, Spekhorst LM, Mangen MJ, Dijkstra G, Löwenberg M, Hoentjen F, van der Meulen-de Jong AE, Pierik M, Ponsioen CY, Bouma G, van der Woude JC, van der Valk ME, Romberg-Camps MJL, Clemens CHM, van de Meeberg P, Mahmmod N, Jansen J, Jharap B, Weersma RK, Oldenburg B, Festen EAM, Fidder HH.

Inflamm Bowel Dis. 2018 May 18;24(6):1298-1306. doi: 10.1093/ibd/izy004.

PMID:
29688413
14.

Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease.

Visschedijk MC, Spekhorst LM, Cheng SC, van Loo ES, Jansen BHD, Blokzijl T, Kil H, de Jong DJ, Pierik M, Maljaars JPWJ, van der Woude CJ, van Bodegraven AA, Oldenburg B, Löwenberg M, Nieuwenhuijs VB, Imhann F, van Sommeren S, Alberts R, Xavier RJ, Dijkstra G, Nico Faber K, Aldaz CM, Weersma RK, Festen EAM.

J Crohns Colitis. 2018 Apr 27;12(5):582-588. doi: 10.1093/ecco-jcc/jjy001.

PMID:
29361163
15.

Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease.

Spekhorst LM, Oldenburg B, van Bodegraven AA, de Jong DJ, Imhann F, van der Meulen-de Jong AE, Pierik MJ, van der Woude JC, Dijkstra G, D'Haens G, Löwenberg M, Weersma RK, Festen EAM; Parelsnoer Institute and the Dutch Initiative on Crohn and Colitis.

World J Gastroenterol. 2017 Dec 14;23(46):8182-8192. doi: 10.3748/wjg.v23.i46.8182.

16.

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease.

Spekhorst LM, Imhann F, Festen EAM, van Bodegraven AA, de Boer NKH, Bouma G, Fidder HH, d'Haens G, Hoentjen F, Hommes DW, de Jong DJ, Löwenberg M, Maljaars PWJ, van der Meulen-de Jong AE, Oldenburg B, Pierik MJ, Ponsioen CY, Stokkers PC, Verspaget HW, Visschedijk MC, van der Woude CJ, Dijkstra G, Weersma RK; Parelsnoer Institute (PSI) and the Dutch Initiative on Crohn and Colitis (ICC).

BMJ Open. 2017 Nov 8;7(11):e016695. doi: 10.1136/bmjopen-2017-016695.

17.

The Impact of Ethnicity and Country of Birth on Inflammatory Bowel Disease Phenotype: a Prospective Cohort Study.

Spekhorst LM, Severs M, de Boer NKH, Festen EAM, Fidder HH, Hoentjen F, Imhann F, de Jong DJ, van der Meulen-de Jong AE, Pierik MJ, van der Woude CJ, Dijkstra G, Ponsioen CY, Löwenberg M, Oldenburg B, Weersma RK; Parelsnoer Institute and the Dutch Initiative on Crohn and Colitis.

J Crohns Colitis. 2017 Dec 4;11(12):1463-1470. doi: 10.1093/ecco-jcc/jjx098.

PMID:
28981621
18.

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J, Eksteen B, Ellinghaus D, Färkkilä M, Festen EAM, Floreani A, Franceschet I, Gotthardt DN, Hirschfield GM, Hoek BV, Holm K, Hohenester S, Hov JR, Imhann F, Invernizzi P, Juran BD, Lenzen H, Lieb W, Liu JZ, Marschall HU, Marzioni M, Melum E, Milkiewicz P, Müller T, Pares A, Rupp C, Rust C, Sandford RN, Schramm C, Schreiber S, Schrumpf E, Silverberg MS, Srivastava B, Sterneck M, Teufel A, Vallier L, Verheij J, Vila AV, Vries B, Zachou K; International PSC Study Group, The UK PSC Consortium, Chapman RW, Manns MP, Pinzani M, Rushbrook SM, Lazaridis KN, Franke A, Anderson CA, Karlsen TH, Ponsioen CY, Weersma RK.

Gut. 2018 Aug;67(8):1517-1524. doi: 10.1136/gutjnl-2016-313598. Epub 2017 Aug 4.

19.

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease.

Imhann F, Vich Vila A, Bonder MJ, Fu J, Gevers D, Visschedijk MC, Spekhorst LM, Alberts R, Franke L, van Dullemen HM, Ter Steege RWF, Huttenhower C, Dijkstra G, Xavier RJ, Festen EAM, Wijmenga C, Zhernakova A, Weersma RK.

Gut. 2018 Jan;67(1):108-119. doi: 10.1136/gutjnl-2016-312135. Epub 2016 Oct 8.

20.

The genetic background of inflammatory bowel disease: from correlation to causality.

Uniken Venema WT, Voskuil MD, Dijkstra G, Weersma RK, Festen EA.

J Pathol. 2017 Jan;241(2):146-158. doi: 10.1002/path.4817. Epub 2016 Nov 15. Review.

PMID:
27785786
21.

Drug Repositioning in Inflammatory Bowel Disease Based on Genetic Information.

Collij V, Festen EA, Alberts R, Weersma RK.

Inflamm Bowel Dis. 2016 Nov;22(11):2562-2570.

PMID:
27753694
22.

Down the line from genome-wide association studies in inflammatory bowel disease: the resulting clinical benefits and the outlook for the future.

Spekhorst LM, Visschedijk MC, Weersma RK, Festen EA.

Expert Rev Clin Immunol. 2015 Jan;11(1):33-44. doi: 10.1586/1744666X.2015.990439. Epub 2014 Dec 10. Review.

PMID:
25493555
23.

Performance of the Montreal classification for inflammatory bowel diseases.

Spekhorst LM, Visschedijk MC, Alberts R, Festen EA, van der Wouden EJ, Dijkstra G, Weersma RK; Dutch Initiative on Crohn and Colitis.

World J Gastroenterol. 2014 Nov 7;20(41):15374-81. doi: 10.3748/wjg.v20.i41.15374.

24.

How will insights from genetics translate to clinical practice in inflammatory bowel disease?

Festen EA, Weersma RK.

Best Pract Res Clin Gastroenterol. 2014 Jun;28(3):387-97. doi: 10.1016/j.bpg.2014.04.002. Epub 2014 May 14. Review.

PMID:
24913379
25.

Multi-ethnic studies in complex traits.

Fu J, Festen EA, Wijmenga C.

Hum Mol Genet. 2011 Oct 15;20(R2):R206-13. doi: 10.1093/hmg/ddr386. Epub 2011 Sep 2. Review.

26.

HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort.

van Sommeren S, Visschedijk MC, Festen EA, de Jong DJ, Ponsioen CY, Wijmenga C, Weersma RK.

Inflamm Bowel Dis. 2011 Aug;17(8):1714-8. doi: 10.1002/ibd.21541. Epub 2010 Nov 28.

PMID:
21744425
27.

Wnt signaling and Dupuytren's disease.

Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, Nürnberg P, Giele H, Ophoff RA, Wijmenga C; Dutch Dupuytren Study Group; German Dupuytren Study Group; LifeLines Cohort Study; BSSH-GODD Consortium.

N Engl J Med. 2011 Jul 28;365(4):307-17. doi: 10.1056/NEJMoa1101029. Epub 2011 Jul 6.

28.

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, Westra HJ, Fehrmann RS, Kurreeman FA, Thomson B, Gupta N, Romanos J, McManus R, Ryan AW, Turner G, Brouwer E, Posthumus MD, Remmers EF, Tucci F, Toes R, Grandone E, Mazzilli MC, Rybak A, Cukrowska B, Coenen MJ, Radstake TR, van Riel PL, Li Y, de Bakker PI, Gregersen PK, Worthington J, Siminovitch KA, Klareskog L, Huizinga TW, Wijmenga C, Plenge RM.

PLoS Genet. 2011 Feb;7(2):e1002004. doi: 10.1371/journal.pgen.1002004. Epub 2011 Feb 24.

29.

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

Festen EA, Goyette P, Green T, Boucher G, Beauchamp C, Trynka G, Dubois PC, Lagacé C, Stokkers PC, Hommes DW, Barisani D, Palmieri O, Annese V, van Heel DA, Weersma RK, Daly MJ, Wijmenga C, Rioux JD.

PLoS Genet. 2011 Jan 27;7(1):e1001283. doi: 10.1371/journal.pgen.1001283.

30.

Association of Crohn's disease-associated NOD2 variants with intestinal failure requiring small bowel transplantation and clinical outcomes.

Janse M, Weersma RK, Sudan DL, Festen EA, Wijmenga C, Dijkstra G, Mercer D.

Gut. 2011 Jun;60(6):877-8; author reply 878-9. doi: 10.1136/gut.2009.196238. Epub 2010 Oct 12. No abstract available.

PMID:
20940282
31.

Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations.

Weersma RK, Crusius JB, Roberts RL, Koeleman BP, Palomino-Morales R, Wolfkamp S, Hollis-Moffatt JE, Festen EA, Meisneris S, Heijmans R, Noble CL, Gearry RB, Barclay ML, Gómez-Garcia M, Lopez-Nevot MA, Nieto A, Rodrigo L, Radstake TR, van Bodegraven AA, Wijmenga C, Merriman TR, Stokkers PC, Peña AS, Martín J, Alizadeh BZ.

Inflamm Bowel Dis. 2010 Dec;16(12):2080-9. doi: 10.1002/ibd.21342.

PMID:
20848524
32.

Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease.

Fransen K, Visschedijk MC, van Sommeren S, Fu JY, Franke L, Festen EA, Stokkers PC, van Bodegraven AA, Crusius JB, Hommes DW, Zanen P, de Jong DJ, Wijmenga C, van Diemen CC, Weersma RK.

Hum Mol Genet. 2010 Sep 1;19(17):3482-8. doi: 10.1093/hmg/ddq264. Epub 2010 Jul 3.

PMID:
20601676
33.

Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease.

de Vries HS, Plantinga TS, van Krieken JH, Stienstra R, van Bodegraven AA, Festen EA, Weersma RK, Crusius JB, Linskens RK, Joosten LA, Netea MG, de Jong DJ.

PLoS One. 2009 Nov 12;4(11):e7818. doi: 10.1371/journal.pone.0007818.

34.

[The genetic basis of inflammatory bowel disease unravelled by genetic association studies].

Visschedijk MC, Festen EA, Wijmenga C, Weersma RK.

Ned Tijdschr Geneeskd. 2009;153:A402. Review. Dutch.

PMID:
19900309
35.

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk.

Festen EA, Stokkers PC, van Diemen CC, van Bodegraven AA, Boezen HM, Crusius BJ, Hommes DW, van der Woude CJ, Balschun T, Verspaget HW, Schreiber S, de Jong DJ, Franke A, Dijkstra G, Wijmenga C, Weersma RK.

Am J Gastroenterol. 2010 Feb;105(2):395-402. doi: 10.1038/ajg.2009.576. Epub 2009 Oct 27. Erratum in: Am J Gastroenterol. 2010 Feb;105(2):479. van der Woude, Janneke C [corrected to van der Woude, C Janneke].

PMID:
19861958
36.

Inflammatory bowel disease and celiac disease: overlaps in the pathology and genetics, and their potential drug targets.

Festen EA, Szperl AM, Weersma RK, Wijmenga C, Wapenaar MC.

Endocr Metab Immune Disord Drug Targets. 2009 Jun;9(2):199-218. Review.

PMID:
19519468
37.

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD.

Gut. 2009 Jun;58(6):799-804. doi: 10.1136/gut.2008.166918. Epub 2009 Feb 6.

38.

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort.

Weersma RK, Stokkers PC, van Bodegraven AA, van Hogezand RA, Verspaget HW, de Jong DJ, van der Woude CJ, Oldenburg B, Linskens RK, Festen EA, van der Steege G, Hommes DW, Crusius JB, Wijmenga C, Nolte IM, Dijkstra G; Dutch Initiative on Crohn and Colitis (ICC).

Gut. 2009 Mar;58(3):388-95. doi: 10.1136/gut.2007.144865. Epub 2008 Sep 29.

PMID:
18824555
39.

Association of DLG5 variants with gluten-sensitive enteropathy.

Festen EA, Zhernakova A, Wijmenga C, Weersma RK.

Gut. 2008 Jul;57(7):1027-8. doi: 10.1136/gut.2007.144857. No abstract available.

PMID:
18559397

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