Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 53

1.

EXPRESS: Low-Grade Albuminuria in Pulmonary Arterial Hypertension.

Nickel N, Perez VAJ, Fessel JP, Cogan J, Hamid R, West JD, de Caestecker M, Yang H, Zamanian RT, Austin E.

Pulm Circ. 2019 Jan 11:2045894018824564. doi: 10.1177/2045894018824564. [Epub ahead of print] No abstract available.

PMID:
30632900
2.

Human PAH is characterized by a pattern of lipid-related insulin resistance.

Hemnes AR, Luther JM, Rhodes CJ, Burgess JP, Carlson J, Fan R, Fessel JP, Fortune N, Gerszten RE, Halliday SJ, Hekmat R, Howard L, Newman JH, Niswender KD, Pugh ME, Robbins IM, Sheng Q, Shibao CA, Shyr Y, Sumner S, Talati M, Wharton J, Wilkins MR, Ye F, Yu C, West J, Brittain EL.

JCI Insight. 2019 Jan 10;4(1). pii: 123611. doi: 10.1172/jci.insight.123611. [Epub ahead of print]

3.

Treatment of Acute Intoxication From Inhaled 1,2-Difluoroethane.

Arroyo JP, Johnson DC, Lewis JB, Al Sheyyab A, King A, Danter MR, McGrane S, Fessel JP.

Ann Intern Med. 2018 Dec 4;169(11):820-822. doi: 10.7326/L18-0186. Epub 2018 Aug 14. No abstract available.

PMID:
30105355
4.

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension.

Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE, Johnson JA, Kaplowitz M, Newman JH, Piana R, Pugh ME, Rice TW, Robbins IM, Wheeler L, Yu C, Loyd JE, West J.

Eur Respir J. 2018 Jun 21;51(6). pii: 1702638. doi: 10.1183/13993003.02638-2017. Print 2018 Jun.

PMID:
29903860
5.

Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation.

Gubert P, Puntel B, Lehmen T, Fessel JP, Cheng P, Bornhorst J, Trindade LS, Avila DS, Aschner M, Soares FAA.

Neurotoxicology. 2018 Jul;67:65-72. doi: 10.1016/j.neuro.2018.04.008. Epub 2018 Apr 16.

PMID:
29673961
6.

Lower Concentrations of Circulating Medium and Long-Chain Acylcarnitines Characterize Insulin Resistance in Persons with HIV.

Bailin SS, Jenkins CA, Petucci C, Culver JA, Shepherd BE, Fessel JP, Hulgan T, Koethe JR.

AIDS Res Hum Retroviruses. 2018 Jun;34(6):536-543. doi: 10.1089/AID.2017.0314. Epub 2018 May 2.

PMID:
29607651
7.

Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.

Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ.

Nucleic Acids Res. 2018 Apr 20;46(7):3458-3467. doi: 10.1093/nar/gky089.

8.

A Metabolic Basis for Endothelial-to-Mesenchymal Transition.

Xiong J, Kawagishi H, Yan Y, Liu J, Wells QS, Edmunds LR, Fergusson MM, Yu ZX, Rovira II, Brittain EL, Wolfgang MJ, Jurczak MJ, Fessel JP, Finkel T.

Mol Cell. 2018 Feb 15;69(4):689-698.e7. doi: 10.1016/j.molcel.2018.01.010. Epub 2018 Feb 8.

9.

Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism.

Warren EB, Aicher AE, Fessel JP, Konradi C.

PLoS One. 2017 Dec 29;12(12):e0190456. doi: 10.1371/journal.pone.0190456. eCollection 2017.

10.

Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin.

Kuck JL, Bastarache JA, Shaver CM, Fessel JP, Dikalov SI, May JM, Ware LB.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):433-437. doi: 10.1016/j.bbrc.2017.11.058. Epub 2017 Nov 9.

11.

Nicotine Adenine Dinucleotides: The Redox Currency of the Cell.

Fessel JP, Oldham WM.

Antioxid Redox Signal. 2018 Jan 20;28(3):165-166. doi: 10.1089/ars.2017.7439.

12.

Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate.

Dixit S, Fessel JP, Harrison FE.

Free Radic Biol Med. 2017 Nov;112:515-523. doi: 10.1016/j.freeradbiomed.2017.08.021. Epub 2017 Aug 31.

13.

Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects.

Chen X, Austin ED, Talati M, Fessel JP, Farber-Eger EH, Brittain EL, Hemnes AR, Loyd JE, West J.

Eur Respir J. 2017 Aug 3;50(2). pii: 1602337. doi: 10.1183/13993003.02337-2016. Print 2017 Aug.

14.

Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension.

Trammell AW, Talati M, Blackwell TR, Fortune NL, Niswender KD, Fessel JP, Newman JH, West JD, Hemnes AR.

Pulm Circ. 2017 Jul-Sep;7(3):624-634. doi: 10.1086/689908. Epub 2017 Aug 7.

15.

Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension.

Dikalova AE, Itani HA, Nazarewicz RR, McMaster WG, Flynn CR, Uzhachenko R, Fessel JP, Gamboa JL, Harrison DG, Dikalov SI.

Circ Res. 2017 Aug 18;121(5):564-574. doi: 10.1161/CIRCRESAHA.117.310933. Epub 2017 Jul 6.

16.

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension.

Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, Roberts LJ 2nd, Hemnes AR, West J, Fessel JP.

Pulm Circ. 2017 Feb 1;7(1):186-199. doi: 10.1086/690236. eCollection 2017 Mar.

17.

Kidney dysfunction in patients with pulmonary arterial hypertension.

Nickel NP, O'Leary JM, Brittain EL, Fessel JP, Zamanian RT, West JD, Austin ED.

Pulm Circ. 2017 Mar 13;7(1):38-54. doi: 10.1086/690018. eCollection 2017 Mar. Review.

18.

Pyridine Dinucleotides from Molecules to Man.

Fessel JP, Oldham WM.

Antioxid Redox Signal. 2018 Jan 20;28(3):180-212. doi: 10.1089/ars.2017.7120. Epub 2017 Jul 25. Review.

19.

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults.

Wells QS, Veatch OJ, Fessel JP, Joon AY, Levinson RT, Mosley JD, Held EP, Lindsay CS, Shaffer CM, Weeke PE, Glazer AM, Bersell KR, Van Driest SL, Karnes JH, Blair MA, Lagrone LW, Su YR, Bowton EA, Feng Z, Ky B, Lenihan DJ, Fisch MJ, Denny JC, Roden DM.

Pharmacogenet Genomics. 2017 Jul;27(7):247-254. doi: 10.1097/FPC.0000000000000284.

20.

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition.

Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP.

Sci Rep. 2017 Feb 16;7:42604. doi: 10.1038/srep42604.

21.

Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease.

Gaskill C, Marriott S, Pratap S, Menon S, Hedges LK, Fessel JP, Kropski JA, Ames D, Wheeler L, Loyd JE, Hemnes AR, Roop DR, Klemm DJ, Austin ED, Majka SM.

Pulm Circ. 2016 Dec;6(4):483-497. doi: 10.1086/688314.

22.

Mitochondrial Haplogroups as a Risk Factor for Herpes Zoster.

Levinson RT, Hulgan T, Kalams SA, Fessel JP, Samuels DC.

Open Forum Infect Dis. 2016 Oct 19;3(4):ofw184. eCollection 2016 Oct.

23.

Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7.

Nguyen TT, Caito SW, Zackert WE, West JD, Zhu S, Aschner M, Fessel JP, Roberts LJ 2nd.

Aging (Albany NY). 2016 Aug;8(8):1759-80. doi: 10.18632/aging.101011.

24.

Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle.

Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR.

Am J Respir Crit Care Med. 2016 Sep 15;194(6):719-28. doi: 10.1164/rccm.201507-1444OC.

25.

Transbronchial Cryobiopsy Can Diagnose Constrictive Bronchiolitis in Veterans of Recent Conflicts in the Middle East.

Lentz RJ, Fessel JP, Johnson JE, Maldonado F, Miller RF, Rickman OB.

Am J Respir Crit Care Med. 2016 Apr 1;193(7):806-8. doi: 10.1164/rccm.201509-1724LE. No abstract available.

26.

Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension.

Brittain EL, Talati M, Fessel JP, Zhu H, Penner N, Calcutt MW, West JD, Funke M, Lewis GD, Gerszten RE, Hamid R, Pugh ME, Austin ED, Newman JH, Hemnes AR.

Circulation. 2016 May 17;133(20):1936-44. doi: 10.1161/CIRCULATIONAHA.115.019351. Epub 2016 Mar 22.

27.

Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis.

Bryant AJ, Robinson LJ, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, McClellan LJ, Polosukhin VV, Tanjore H, McConaha ME, Gleaves LA, Talati MA, Hemnes AR, Fessel JP, Lawson WE, Blackwell TS, West JD.

Pulm Circ. 2015 Dec;5(4):681-90. doi: 10.1086/683811.

28.

Redox biology in pulmonary arterial hypertension (2013 Grover Conference Series).

Fessel JP, West JD.

Pulm Circ. 2015 Dec;5(4):599-609. doi: 10.1086/683814. Review.

29.

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.

Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, Dong HJ, Gleaves LA, Carrier EJ, Gaskill C, Scott EW, Majka SM, Fessel JP, Haase VH, West JD, Blackwell TS, Lawson WE.

Am J Physiol Lung Cell Mol Physiol. 2016 Feb 1;310(3):L249-62. doi: 10.1152/ajplung.00258.2015. Epub 2015 Dec 4.

30.

Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism.

Chen X, Talati M, Fessel JP, Hemnes AR, Gladson S, French J, Shay S, Trammell A, Phillips JA, Hamid R, Cogan JD, Dawson EP, Womble KE, Hedges LK, Martinez EG, Wheeler LA, Loyd JE, Majka SJ, West J, Austin ED.

Circulation. 2016 Jan 5;133(1):82-97. doi: 10.1161/CIRCULATIONAHA.115.016133. Epub 2015 Oct 20.

31.

LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small-cell lung cancer (NSCLC) cells.

Whang YM, Park SI, Trenary IA, Egnatchik RA, Fessel JP, Kaufman JM, Carbone DP, Young JD.

Oncogene. 2016 Feb 18;35(7):856-66. doi: 10.1038/onc.2015.140. Epub 2015 Jun 29.

32.

Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.

West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM.

Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C415-30. doi: 10.1152/ajpcell.00057.2014. Epub 2014 May 28.

33.

Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.

West J, Austin E, Fessel JP, Loyd J, Hamid R.

Drug Discov Today. 2014 Aug;19(8):1241-5. doi: 10.1016/j.drudis.2014.04.015. Epub 2014 May 2. Review.

34.

Interaction between bone morphogenetic protein receptor type 2 and estrogenic compounds in pulmonary arterial hypertension.

Fessel JP, Chen X, Frump A, Gladson S, Blackwell T, Kang C, Johnson J, Loyd JE, Hemnes A, Austin E, West J.

Pulm Circ. 2013 Sep;3(3):564-77. doi: 10.1086/674312. Epub 2013 Dec 2.

35.

Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension.

Hemnes AR, Brittain EL, Trammell AW, Fessel JP, Austin ED, Penner N, Maynard KB, Gleaves L, Talati M, Absi T, Disalvo T, West J.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):325-34. doi: 10.1164/rccm.201306-1086OC.

36.

Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.

Fessel JP, Flynn CR, Robinson LJ, Penner NL, Gladson S, Kang CJ, Wasserman DH, Hemnes AR, West JD.

Am J Respir Cell Mol Biol. 2013 Nov;49(5):778-87. doi: 10.1165/rcmb.2012-0463OC.

37.

Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling.

Chow K, Fessel JP, Kaoriihida-Stansbury, Schmidt EP, Gaskill C, Alvarez D, Graham B, Harrison DG, Wagner DH Jr, Nozik-Grayck E, West JD, Klemm DJ, Majka SM.

Pulm Circ. 2013 Jan;3(1):31-49. doi: 10.4103/2045-8932.109912.

38.

A potential role for insulin resistance in experimental pulmonary hypertension.

West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR.

Eur Respir J. 2013 Apr;41(4):861-71. doi: 10.1183/09031936.00030312. Epub 2012 Aug 30.

39.

Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming.

Fessel JP, Hamid R, Wittmann BM, Robinson LJ, Blackwell T, Tada Y, Tanabe N, Tatsumi K, Hemnes AR, West JD.

Pulm Circ. 2012 Apr-Jun;2(2):201-13. doi: 10.4103/2045-8932.97606.

40.

Outcomes in elderly intensive care unit patients, pulmonary hypertension in sickle cell disease, and total liquid ventilation for therapeutic hypothermia after cardiac arrest in rabbits.

Brummel NE, Pugh ME, Fessel JP.

Am J Respir Crit Care Med. 2012 Feb 15;185(4):453-4. doi: 10.1164/rccm.201109-1608RR. No abstract available.

41.

Dysautonomia: perioperative implications.

Mustafa HI, Fessel JP, Barwise J, Shannon JR, Raj SR, Diedrich A, Biaggioni I, Robertson D.

Anesthesiology. 2012 Jan;116(1):205-15. doi: 10.1097/ALN.0b013e31823db712. Review.

42.

The genetics of pulmonary arterial hypertension in the post-BMPR2 era.

Fessel JP, Loyd JE, Austin ED.

Pulm Circ. 2011 Jul-Sep;1(3):305-19. doi: 10.4103/2045-8932.87293.

43.

Oxidative injury is a common consequence of BMPR2 mutations.

Lane KL, Talati M, Austin E, Hemnes AR, Johnson JA, Fessel JP, Blackwell T, Mernaugh RL, Robinson L, Fike C, Roberts LJ 2nd, West J.

Pulm Circ. 2011;1(1):72-83.

44.

Plasma biomarkers of oxidant stress and development of organ failure in severe sepsis.

Ware LB, Fessel JP, May AK, Roberts LJ 2nd.

Shock. 2011 Jul;36(1):12-7. doi: 10.1097/SHK.0b013e318217025a.

45.

Oxygen therapy-use and abuse.

Jackson Roberts L 2nd, Fessel J, Arendash G.

Clin Cardiol. 2010 Jan;33(1):52. doi: 10.1002/clc.20697. No abstract available.

46.

Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension.

Patel M, Liang LP, Hou H, Williams BB, Kmiec M, Swartz HM, Fessel JP, Roberts LJ 2nd.

J Neurochem. 2008 Jan;104(1):264-70. Epub 2007 Oct 22.

47.

The biochemistry of the isoprostane, neuroprostane, and isofuran Pathways of lipid peroxidation.

Roberts LJ 2nd, Fessel JP, Davies SS.

Brain Pathol. 2005 Apr;15(2):143-8. Review.

PMID:
15912887
48.

Isofurans: novel products of lipid peroxidation that define the occurrence of oxidant injury in settings of elevated oxygen tension.

Fessel JP, Jackson Roberts L.

Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):202-9. Review.

PMID:
15650408
49.

A nomenclature system for isofurans.

Taber DF, Fessel JP, Roberts LJ 2nd.

Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):47-50.

PMID:
15165030
50.

The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation.

Roberts LJ 2nd, Fessel JP.

Chem Phys Lipids. 2004 Mar;128(1-2):173-86. Review.

PMID:
15037162

Supplemental Content

Loading ...
Support Center