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Items: 1 to 50 of 200

1.

Is there sufficient evidence that the melatonin binding site MT3 is quinone reductase 2?

Boutin JA, Ferry G.

J Pharmacol Exp Ther. 2018 Nov 2. pii: jpet.118.253260. doi: 10.1124/jpet.118.253260. [Epub ahead of print]

2.

Ribosome reader to Royal Society leader: a biologist's road to the Nobel.

Ferry G.

Nature. 2018 Sep;561(7721):32. doi: 10.1038/d41586-018-06138-1. No abstract available.

PMID:
30181641
3.

Anna Morandi: anatomist of Enlightenment Bologna.

Ferry G.

Lancet. 2018 Aug 4;392(10145):375. doi: 10.1016/S0140-6736(18)31661-1. No abstract available.

PMID:
30102164
4.

Women making medical history: introducing A Woman's Place.

Ferry G.

Lancet. 2018 Aug 4;392(10145):370. doi: 10.1016/S0140-6736(18)31646-5. No abstract available.

PMID:
30102163
5.

Natural Inhibitors of the RhoA-p115 Complex from the Bark of Meiogyne baillonii.

Olivon F, Nothias LF, Dumontet V, Retailleau P, Berger S, Ferry G, Cohen W, Pfeiffer B, Boutin JA, Scalbert E, Roussi F, Litaudon M.

J Nat Prod. 2018 Jul 27;81(7):1610-1618. doi: 10.1021/acs.jnatprod.8b00209. Epub 2018 Jul 3.

PMID:
29969260
6.

A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot.

Petit AP, Garcia-Petit C, Bueren-Calabuig JA, Vuillard LM, Ferry G, Boutin JA.

J Biol Chem. 2018 Jun 8;293(23):9064-9077. doi: 10.1074/jbc.RA117.001123. Epub 2018 Apr 25.

PMID:
29695506
7.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.

Damian M, Pons V, Renault P, M'Kadmi C, Delort B, Hartmann L, Kaya AI, Louet M, Gagne D, Ben Haj Salah K, Denoyelle S, Ferry G, Boutin JA, Wagner R, Fehrentz JA, Martinez J, Marie J, Floquet N, Galès C, Mary S, Hamm HE, Banères JL.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4501-4506. doi: 10.1073/pnas.1712725115. Epub 2018 Apr 9.

8.

Oxidative stress and neurodegeneration: The possible contribution of quinone reductase 2.

Cassagnes LE, Chhour M, Pério P, Sudor J, Gayon R, Ferry G, Boutin JA, Nepveu F, Reybier K.

Free Radic Biol Med. 2018 May 20;120:56-61. doi: 10.1016/j.freeradbiomed.2018.03.002. Epub 2018 Mar 8.

PMID:
29526807
9.

Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction.

Gerard CJJ, Ferry G, Vuillard LM, Boutin JA, Chavas LMG, Huet T, Ferte N, Grossier R, Candoni N, Veesler S.

Acta Crystallogr F Struct Biol Commun. 2017 Oct 1;73(Pt 10):574-578. doi: 10.1107/S2053230X17013826. Epub 2017 Oct 2.

PMID:
28994406
10.

Cutting Edge: Murine NK Cells Degranulate and Retain Cytotoxic Function without Store-Operated Calcium Entry.

Freund-Brown J, Choa R, Singh BK, Robertson TF, Ferry GM, Viver E, Bassiri H, Burkhardt JK, Kambayashi T.

J Immunol. 2017 Aug 9. pii: ji1700340. doi: 10.4049/jimmunol.1700340. [Epub ahead of print]

PMID:
28794231
11.

Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives.

Cassagnes LE, Rakotoarivelo N, Sirigu S, Pério P, Najahi E, Chavas LM, Thompson A, Gayon R, Ferry G, Boutin JA, Valentin A, Reybier K, Nepveu F.

Molecules. 2017 Jan 30;22(2). pii: E210. doi: 10.3390/molecules22020210.

12.

Screening ubiquitin specific protease activities using chemically synthesized ubiquitin and ubiquitinated peptides.

Bacchi M, Fould B, Jullian M, Kreiter A, Maurras A, Nosjean O, Coursindel T, Puget K, Ferry G, Boutin JA.

Anal Biochem. 2017 Feb 15;519:57-70. doi: 10.1016/j.ab.2016.12.014. Epub 2016 Dec 18.

PMID:
27993553
13.

Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1.

Pautus S, Alami M, Adam F, Bernadat G, Lawrence DA, De Carvalho A, Ferry G, Rupin A, Hamze A, Champy P, Bonneau N, Gloanec P, Peglion JL, Brion JD, Bianchini EP, Borgel D.

Sci Rep. 2016 Nov 23;6:36462. doi: 10.1038/srep36462.

14.

Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6).

Bacchi M, Jullian M, Sirigu S, Fould B, Huet T, Bruyand L, Antoine M, Vuillard L, Ronga L, Chavas LM, Nosjean O, Ferry G, Puget K, Boutin JA.

Protein Sci. 2016 Dec;25(12):2225-2242. doi: 10.1002/pro.3051. Epub 2016 Oct 13.

15.

Molecular Dynamics Simulations and Kinetic Measurements to Estimate and Predict Protein-Ligand Residence Times.

Mollica L, Theret I, Antoine M, Perron-Sierra F, Charton Y, Fourquez JM, Wierzbicki M, Boutin JA, Ferry G, Decherchi S, Bottegoni G, Ducrot P, Cavalli A.

J Med Chem. 2016 Aug 11;59(15):7167-76. doi: 10.1021/acs.jmedchem.6b00632. Epub 2016 Jul 22.

PMID:
27391254
16.

Detecting Microbial Dysbiosis Associated with Pediatric Crohn Disease Despite the High Variability of the Gut Microbiota.

Wang F, Kaplan JL, Gold BD, Bhasin MK, Ward NL, Kellermayer R, Kirschner BS, Heyman MB, Dowd SE, Cox SB, Dogan H, Steven B, Ferry GD, Cohen SA, Baldassano RN, Moran CJ, Garnett EA, Drake L, Otu HH, Mirny LA, Libermann TA, Winter HS, Korolev KS.

Cell Rep. 2016 Feb 2;14(4):945-955. doi: 10.1016/j.celrep.2015.12.088. Epub 2016 Jan 21.

17.

Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles.

Logez C, Damian M, Legros C, Dupré C, Guéry M, Mary S, Wagner R, M'Kadmi C, Nosjean O, Fould B, Marie J, Fehrentz JA, Martinez J, Ferry G, Boutin JA, Banères JL.

Biochemistry. 2016 Jan 12;55(1):38-48. doi: 10.1021/acs.biochem.5b01040. Epub 2015 Dec 24.

PMID:
26701065
18.

Obtaining anti-type 1 melatonin receptor antibodies by immunization with melatonin receptor-expressing cells.

Cordeiro N, Wijkhuisen A, Savatier A, Moulharat N, Ferry G, Léonetti M.

J Immunol Methods. 2016 Jan;428:37-41. doi: 10.1016/j.jim.2015.11.011. Epub 2015 Dec 2.

PMID:
26657944
19.

In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones.

Cassagnes LE, Perio P, Ferry G, Moulharat N, Antoine M, Gayon R, Boutin JA, Nepveu F, Reybier K.

Free Radic Biol Med. 2015 Dec;89:126-34. doi: 10.1016/j.freeradbiomed.2015.07.150. Epub 2015 Sep 18.

PMID:
26386287
20.

Medical periodicals: mining the past.

Ferry G.

Lancet. 2015 Jun 27;385(9987):2569-70. doi: 10.1016/S0140-6736(15)61151-5. No abstract available.

PMID:
26122152
21.

Molecular mechanisms of transcriptional control by Rev-erbα: An energetic foundation for reconciling structure and binding with biological function.

Vaissière A, Berger S, Harrus D, Dacquet C, Le Maire A, Boutin JA, Ferry G, Royer CA.

Protein Sci. 2015 Jul;24(7):1129-46. doi: 10.1002/pro.2701. Epub 2015 Jun 11.

22.

¹⁹F nuclear magnetic resonance screening of glucokinase activators.

Assemat O, Antoine M, Fourquez JM, Wierzbicki M, Charton Y, Hennig P, Perron-Sierra F, Ferry G, Boutin JA, Delsuc MA.

Anal Biochem. 2015 May 15;477:62-8. doi: 10.1016/j.ab.2015.02.006. Epub 2015 Feb 12.

PMID:
25684110
23.

Dorothy Hodgkin: on proteins and patterns.

Ferry G.

Lancet. 2014 Oct 25;384(9953):1496-7. doi: 10.1016/S0140-6736(14)61912-7. No abstract available.

PMID:
25390567
24.

History: Fifty years of EMBO.

Ferry G.

Nature. 2014 Jul 10;511(7508):150-1. No abstract available.

PMID:
25013879
25.

Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes.

Logez C, Berger S, Legros C, Banères JL, Cohen W, Delagrange P, Nosjean O, Boutin JA, Ferry G, Simonin F, Wagner R.

PLoS One. 2014 Jun 24;9(6):e100616. doi: 10.1371/journal.pone.0100616. eCollection 2014.

26.

DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis.

Harris RA, Nagy-Szakal D, Mir SA, Frank E, Szigeti R, Kaplan JL, Bronsky J, Opekun A, Ferry GD, Winter H, Kellermayer R.

Epigenetics. 2014 Aug;9(8):1131-7. doi: 10.4161/epi.29446. Epub 2014 Jun 17.

27.

History: Women in crystallography.

Ferry G.

Nature. 2014 Jan 30;505(7485):609-11. No abstract available.

PMID:
24482834
28.

The natural course of inflammatory bowel disease-indeterminate from childhood to adulthood: within a 25 year period.

Malaty HM, Mehta S, Abraham B, Garnett EA, Ferry GD.

Clin Exp Gastroenterol. 2013 Jul 23;6:115-21. doi: 10.2147/CEG.S44700. Print 2013.

29.

The natural history of ulcerative colitis in a pediatric population: a follow-up population-based cohort study.

Malaty HM, Abraham BP, Mehta S, Garnett EA, Ferry GD.

Clin Exp Gastroenterol. 2013 Jun 17;6:77-83. doi: 10.2147/CEG.S40259. Print 2013.

30.

S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.

Burbridge MF, Bossard CJ, Saunier C, Fejes I, Bruno A, Léonce S, Ferry G, Da Violante G, Bouzom F, Cattan V, Jacquet-Bescond A, Comoglio PM, Lockhart BP, Boutin JA, Cordi A, Ortuno JC, Pierré A, Hickman JA, Cruzalegui FH, Depil S.

Mol Cancer Ther. 2013 Sep;12(9):1749-62. doi: 10.1158/1535-7163.MCT-13-0075. Epub 2013 Jun 26.

31.

Scientific heritage: Science today, history tomorrow.

Ferry G.

Nature. 2013 Jan 3;493(7430):19-21. doi: 10.1038/493019a. No abstract available.

PMID:
23282348
32.

Mutagenic analysis in a pure molecular system shows that thioredoxin-interacting protein residue Cys247 is necessary and sufficient for a mixed disulfide formation with thioredoxin.

Fould B, Lamamy V, Guenin SP, Ouvry C, Cogé F, Boutin JA, Ferry G.

Protein Sci. 2012 Sep;21(9):1323-33. doi: 10.1002/pro.2119. Epub 2012 Aug 9.

33.

Predictors of proctocolectomy in children with ulcerative colitis.

Kelley-Quon LI, Jen HC, Ziring DA, Gupta N, Kirschner BS, Ferry GD, Cohen SA, Winter HS, Heyman MB, Gold BD, Shew SB.

J Pediatr Gastroenterol Nutr. 2012 Nov;55(5):534-40. doi: 10.1097/MPG.0b013e3182619d26.

34.

Genome-wide peripheral blood leukocyte DNA methylation microarrays identified a single association with inflammatory bowel diseases.

Harris RA, Nagy-Szakal D, Pedersen N, Opekun A, Bronsky J, Munkholm P, Jespersgaard C, Andersen P, Melegh B, Ferry G, Jess T, Kellermayer R.

Inflamm Bowel Dis. 2012 Dec;18(12):2334-41. doi: 10.1002/ibd.22956. Epub 2012 Mar 29.

35.

Equity of inpatient health care in rural Tanzania: a population- and facility-based survey.

Ferry GA, Dickson SR, Mbaruku G, Freedman LP, Kruk ME.

Int J Equity Health. 2012 Feb 15;11:7. doi: 10.1186/1475-9276-11-7.

36.

The active conformation of human glucokinase is not altered by allosteric activators.

Petit P, Antoine M, Ferry G, Boutin JA, Lagarde A, Gluais L, Vincentelli R, Vuillard L.

Acta Crystallogr D Biol Crystallogr. 2011 Nov;67(Pt 11):929-35. doi: 10.1107/S0907444911036729. Epub 2011 Oct 19.

PMID:
22101819
37.

Insights into the redox cycle of human quinone reductase 2.

Reybier K, Perio P, Ferry G, Bouajila J, Delagrange P, Boutin JA, Nepveu F.

Free Radic Res. 2011 Oct;45(10):1184-95. doi: 10.3109/10715762.2011.605788. Epub 2011 Aug 9.

PMID:
21762045
38.

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

Ferry G, Studeny A, Bossard C, Kubara PM, Zeyer D, Renaud JP, Casara P, de Nanteuil G, Wierzbicki M, Pfeiffer B, Prudhomme M, Leonce S, Pierré A, Boutin JA, Golsteyn RM.

Life Sci. 2011 Aug 15;89(7-8):259-68. doi: 10.1016/j.lfs.2011.06.010. Epub 2011 Jun 29.

PMID:
21736880
39.

X-ray structural studies of quinone reductase 2 nanomolar range inhibitors.

Pegan SD, Sturdy M, Ferry G, Delagrange P, Boutin JA, Mesecar AD.

Protein Sci. 2011 Jul;20(7):1182-95. doi: 10.1002/pro.647. Epub 2011 May 23.

40.

Inflammatory bowel disease characteristics in Hispanic children in Texas.

Hattar LN, Abraham BP, Malaty HM, Smith EO, Ferry GD.

Inflamm Bowel Dis. 2012 Mar;18(3):546-54. doi: 10.1002/ibd.21698. Epub 2011 Mar 31.

PMID:
21456045
41.

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn's disease in children: REACH open-label extension.

Hyams J, Walters TD, Crandall W, Kugathasan S, Griffiths A, Blank M, Johanns J, Lang Y, Markowitz J, Cohen S, Winter HS, Veereman-Wauters G, Ferry G, Baldassano R.

Curr Med Res Opin. 2011 Mar;27(3):651-62. doi: 10.1185/03007995.2010.547575. Epub 2011 Jan 18.

PMID:
21241207
42.

Meganuclease-driven targeted integration in CHO-K1 cells for the fast generation of HTS-compatible cell-based assays.

Cabaniols JP, Ouvry C, Lamamy V, Fery I, Craplet ML, Moulharat N, Guenin SP, Bedut S, Nosjean O, Ferry G, Devavry S, Jacqmarcq C, Lebuhotel C, Mathis L, Delenda C, Boutin JA, Duchâteau P, Cogé F, Pâques F.

J Biomol Screen. 2010 Sep;15(8):956-67. doi: 10.1177/1087057110375115. Epub 2010 Jul 12.

PMID:
20625180
43.

The making of an exceptional scientist.

Ferry G.

Nature. 2010 Apr 29;464(7293):1268-70. doi: 10.1038/4641268a. No abstract available.

PMID:
20428143
44.

Old and new inhibitors of quinone reductase 2.

Ferry G, Hecht S, Berger S, Moulharat N, Coge F, Guillaumet G, Leclerc V, Yous S, Delagrange P, Boutin JA.

Chem Biol Interact. 2010 Jul 30;186(2):103-9. doi: 10.1016/j.cbi.2010.04.006. Epub 2010 May 4.

PMID:
20399199
45.

Q&A: Georgina Ferry on writing biography. Interview by Nicola Jones.

Ferry G.

Nature. 2010 Feb 25;463(7284):1025. doi: 10.1038/4631025a. No abstract available.

PMID:
20182497
46.

Phase I trial of sargramostim in pediatric Crohn's disease.

Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, Mamula P, Baldassano RN.

Inflamm Bowel Dis. 2010 Jul;16(7):1203-8. doi: 10.1002/ibd.21204.

PMID:
20052780
47.

Children's Digestive Health and Nutrition Foundation: building on the past, a foundation for the future.

Ferry GD, Balistreri WF, Barnard JA.

J Pediatr Gastroenterol Nutr. 2010 Feb;50(2):230-3. doi: 10.1097/MPG.0b013e3181cc7ea4. No abstract available.

PMID:
20038845
48.

Rising incidence of inflammatory bowel disease among children: a 12-year study.

Malaty HM, Fan X, Opekun AR, Thibodeaux C, Ferry GD.

J Pediatr Gastroenterol Nutr. 2010 Jan;50(1):27-31. doi: 10.1097/MPG.0b013e3181b99baa.

PMID:
19934770
49.

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Alliance for Pediatric IBD, Silber G, Wrobel I, Quiros A; International IBD Genetics Consortium, Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H.

Nat Genet. 2009 Dec;41(12):1335-40. doi: 10.1038/ng.489. Epub 2009 Nov 15.

50.

Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, Winter HS, Baldassano RN, Abramson O, Smith T, Heyman MB.

Inflamm Bowel Dis. 2010 Apr;16(4):638-44. doi: 10.1002/ibd.21099.

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