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Items: 40

1.

Fas activation alters tight junction proteins in acute lung injury.

Herrero R, Prados L, Ferruelo A, Puig F, Pandolfi R, Guillamat-Prats R, Moreno L, Matute-Bello G, Artigas A, Esteban A, Lorente JÁ.

Thorax. 2019 Jan;74(1):69-82. doi: 10.1136/thoraxjnl-2018-211535. Epub 2018 Nov 1.

PMID:
30385692
2.

MicroRNAs as biomarkers of acute lung injury.

Ferruelo A, Peñuelas Ó, Lorente JA.

Ann Transl Med. 2018 Jan;6(2):34. doi: 10.21037/atm.2018.01.10. Review.

3.

Effect of Simvastatin Treatment on "In Vitro" NLRP1 Inflammasome Expression in Peripheral Arterial Disease.

Bleda S, de Haro J, Lopez de Maturana I, Varela C, Ferruelo A, Acin F.

Ann Vasc Surg. 2016 Oct;36:260-264. doi: 10.1016/j.avsg.2016.05.090. Epub 2016 Jul 15.

PMID:
27423725
4.

Elevated levels of triglycerides and vldl-cholesterol provoke activation of nlrp1 inflammasome in endothelial cells.

Bleda S, de Haro J, Varela C, Ferruelo A, Acin F.

Int J Cardiol. 2016 Oct 1;220:52-5. doi: 10.1016/j.ijcard.2016.06.193. Epub 2016 Jun 25.

PMID:
27372042
5.

Characteristics of microRNAs and their potential relevance for the diagnosis and therapy of the acute respiratory distress syndrome: from bench to bedside.

Cardinal-Fernández P, Ferruelo A, Esteban A, Lorente JA.

Transl Res. 2016 Mar;169:102-11. doi: 10.1016/j.trsl.2015.11.004. Epub 2015 Nov 24. Review.

PMID:
26687392
6.

Inhibition of Nitro-Oxidative Stress Attenuates Pulmonary and Systemic Injury Induced by High-Tidal Volume Mechanical Ventilation.

Martínez-Caro L, Nin N, Sánchez-Rodríguez C, Ferruelo A, El Assar M, de Paula M, Fernández-Segoviano P, Esteban A, Lorente JA.

Shock. 2015 Jul;44(1):36-43. doi: 10.1097/SHK.0000000000000381.

PMID:
25895143
7.

Aspirin therapy inhibits NLRP1 (nucleotide-binding domain-like receptor protein 1) inflammasome gene expression in patients with peripheral artery disease.

Bleda S, De Haro J, Varela C, Ferruelo A, Acin F.

J Vasc Surg. 2015 Apr;61(4):1103-4. doi: 10.1016/j.jvs.2014.12.056. No abstract available.

8.

Influence of mechanical ventilation and sepsis on redox balance in diaphragm, myocardium, limb muscles, and lungs.

Chacon-Cabrera A, Rojas Y, Martínez-Caro L, Vila-Ubach M, Nin N, Ferruelo A, Esteban A, Lorente JA, Barreiro E.

Transl Res. 2014 Dec;164(6):477-95. doi: 10.1016/j.trsl.2014.07.003. Epub 2014 Aug 7.

PMID:
25168016
9.

Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-kβ.

Ferruelo A, de Las Heras MM, Redondo C, Ramón de Fata F, Romero I, Angulo JC.

Actas Urol Esp. 2014 Sep;38(7):429-37. doi: 10.1016/j.acuro.2014.02.017. Epub 2014 May 14. English, Spanish.

PMID:
24836925
10.

Effects of resveratrol and other wine polyphenols on the proliferation, apoptosis and androgen receptor expression in LNCaP cells.

Ferruelo A, Romero I, Cabrera PM, Arance I, Andrés G, Angulo JC.

Actas Urol Esp. 2014 Jul-Aug;38(6):397-404. doi: 10.1016/j.acuro.2014.02.012. Epub 2014 Apr 13. English, Spanish.

PMID:
24726691
11.

Circulating anti-β2-glycoprotein I antibodies of peripheral arterial disease patients trigger a genomic overexpression of Toll-like receptor 4 in endothelial cells.

Varela C, de Haro J, Bleda S, Rodriguez-Padilla J, Ferruelo A, Acín F.

J Vasc Surg. 2015 Apr;61(4):1041-9.e1. doi: 10.1016/j.jvs.2013.11.066. Epub 2014 Jan 25.

12.

NLRP1 inflammasome, and not NLRP3, is the key in the shift to proinflammatory state on endothelial cells in peripheral arterial disease.

Bleda S, de Haro J, Varela C, Esparza L, Ferruelo A, Acin F.

Int J Cardiol. 2014 Mar 15;172(2):e282-4. doi: 10.1016/j.ijcard.2013.12.201. Epub 2014 Jan 9. No abstract available.

PMID:
24439873
13.

The role of matrix metalloproteinase MMP-9 and TIMP-2 tissue inhibitor of metalloproteinases as serum markers of bladder cancer.

Ramón de Fata F, Ferruelo A, Andrés G, Gimbernat H, Sánchez-Chapado M, Angulo JC.

Actas Urol Esp. 2013 Sep;37(8):480-8. doi: 10.1016/j.acuro.2013.05.004. Epub 2013 Jul 31.

PMID:
23916137
14.

Antioxidant effect of human adult adipose-derived stromal stem cells in alveolar epithelial cells undergoing stretch.

Peñuelas O, Melo E, Sánchez C, Sánchez I, Quinn K, Ferruelo A, Pérez-Vizcaíno F, Esteban A, Navajas D, Nin N, Lorente JA, Farré R.

Respir Physiol Neurobiol. 2013 Aug 1;188(1):1-8. doi: 10.1016/j.resp.2013.04.007. Epub 2013 Apr 30.

PMID:
23643709
15.

Genetic predisposition to acute kidney injury induced by severe sepsis.

Cardinal-Fernández P, Ferruelo A, El-Assar M, Santiago C, Gómez-Gallego F, Martín-Pellicer A, Frutos-Vivar F, Peñuelas O, Nin N, Esteban A, Lorente JA.

J Crit Care. 2013 Aug;28(4):365-70. doi: 10.1016/j.jcrc.2012.11.010. Epub 2013 Mar 15.

PMID:
23499421
16.

Genetic predisposition to acute respiratory distress syndrome in patients with severe sepsis.

Cardinal-Fernández P, Ferruelo A, El-Assar M, Santiago C, Gómez-Gallego F, Martín-Pellicer A, Frutos-Vivar F, Peñuelas O, Nin N, Esteban A, Lorente JA.

Shock. 2013 Mar;39(3):255-60. doi: 10.1097/SHK.0b013e3182866ff9.

PMID:
23364437
17.

Role of peroxynitrite in sepsis-induced acute kidney injury in an experimental model of sepsis in rats.

Seija M, Baccino C, Nin N, Sánchez-Rodríguez C, Granados R, Ferruelo A, Martínez-Caro L, Ruíz-Cabello J, de Paula M, Noboa O, Esteban A, Lorente JA.

Shock. 2012 Oct;38(4):403-10. doi: 10.1097/SHK.0b013e31826660f2.

PMID:
22777123
18.

[Genetic determinants of acute renal damage risk and prognosis: a systematic review].

Cardinal-Fernández P, Ferruelo A, Martín-Pellicer A, Nin N, Esteban A, Lorente JA.

Med Intensiva. 2012 Dec;36(9):626-33. doi: 10.1016/j.medin.2012.02.002. Epub 2012 Mar 19. Review. Spanish.

19.

Lung histopathological findings in fatal pandemic influenza A (H1N1).

Nin N, Sánchez-Rodríguez C, Ver LS, Cardinal P, Ferruelo A, Soto L, Deicas A, Campos N, Rocha O, Ceraso DH, El-Assar M, Ortín J, Fernández-Segoviano P, Esteban A, Lorente JA.

Med Intensiva. 2012 Jan-Feb;36(1):24-31. doi: 10.1016/j.medin.2011.10.005. Epub 2011 Dec 10.

20.

Vascular endothelial growth factor polymorphisms are involved in the late vascular complications in Type II diabetic patients.

Bleda S, De Haro J, Varela C, Esparza L, Ferruelo A, Acin F.

Diab Vasc Dis Res. 2012 Jan;9(1):68-74. doi: 10.1177/1479164111426162. Epub 2011 Nov 7.

PMID:
22064697
21.

Vascular dysfunction in sepsis: effects of the peroxynitrite decomposition catalyst MnTMPyP.

Nin N, El-Assar M, Sánchez C, Ferruelo A, Sánchez-Ferrer A, Martínez-Caro L, Rojas Y, Paula Md, Hurtado J, Esteban A, Lorente JA.

Shock. 2011 Aug;36(2):156-61. doi: 10.1097/SHK.0b013e31821e50de.

PMID:
21522041
22.

[Detection and molecular staging of bladder cancer using real-time RT-PCR for gelatinases (MMP-2, MMP-9) and TIMP-2 in peripheral blood].

Angulo JC, Ferruelo A, Rodríguez-Barbero JM, Núñez C, de Fata FR, González J.

Actas Urol Esp. 2011 Mar;35(3):127-36. doi: 10.1016/j.acuro.2010.10.006. Epub 2011 Feb 18. Spanish.

PMID:
21334102
23.

Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times.

Ferruelo A, El-Assar M, Lorente JA, Nin N, Peñuelas O, Fernández-Segoviano P, Gonzalez C, Esteban A.

Int J Clin Exp Pathol. 2011 Jan 6;4(2):156-61.

24.

Role of free radicals in vascular dysfunction induced by high tidal volume ventilation.

Martínez-Caro L, Lorente JA, Marín-Corral J, Sánchez-Rodríguez C, Sánchez-Ferrer A, Nin N, Ferruelo A, de Paula M, Fernández-Segoviano P, Barreiro E, Esteban A.

Intensive Care Med. 2009 Jun;35(6):1110-9. doi: 10.1007/s00134-009-1469-5. Epub 2009 Apr 10.

PMID:
19360397
25.

Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.

Rodríguez-Acebes S, de la Cueva P, Fernández-Hernando C, Ferruelo AJ, Lasunción MA, Rawson RB, Martínez-Botas J, Gómez-Coronado D.

Biochem J. 2009 May 13;420(2):305-15. doi: 10.1042/BJ20081909.

26.

Dose-dependent dual effects of cholesterol and desmosterol on J774 macrophage proliferation.

Rodríguez-Acebes S, Cueva P, Ferruelo AJ, Fernández-Hernando C, Lasunción MA, Martínez-Botas J, Gómez-Coronado D.

Biochem Biophys Res Commun. 2008 Dec 12;377(2):484-488. doi: 10.1016/j.bbrc.2008.09.140. Epub 2008 Oct 11.

PMID:
18851952
27.

High-tidal volume ventilation aggravates sepsis-induced multiorgan dysfunction in a dexamethasone-inhibitable manner.

Nin N, Lorente JA, Fernández-Segoviano P, De Paula M, Ferruelo A, Esteban A.

Shock. 2009 Apr;31(4):429-34. doi: 10.1097/SHK.0b013e318188b720.

PMID:
18791491
28.

Rats surviving injurious mechanical ventilation show reversible pulmonary, vascular and inflammatory changes.

Nin N, Lorente JA, de Paula M, El Assar M, Vallejo S, Peñuelas O, Fernández-Segoviano P, Ferruelo A, Sánchez-Ferrer A, Esteban A.

Intensive Care Med. 2008 May;34(5):948-56. doi: 10.1007/s00134-007-0959-6. Epub 2008 Jan 5.

PMID:
18180906
29.
30.

Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin.

Suárez Y, Fernández C, Gómez-Coronado D, Ferruelo AJ, Dávalos A, Martínez-Botas J, Lasunción MA.

Cardiovasc Res. 2004 Nov 1;64(2):346-55.

PMID:
15485695
31.

Prostate apoptosis after doxazosin treatment in the spontaneous hypertensive rat model.

Lujan M, Ferruelo A, Paez A, Moreno A, Berenguer A.

BJU Int. 2004 Feb;93(3):410-4.

PMID:
14764147
32.

Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells.

Fernández C, Suárez Y, Ferruelo AJ, Gómez-Coronado D, Lasunción MA.

Biochem J. 2002 Aug 15;366(Pt 1):109-19.

33.

Polyphenols in red wine inhibit the proliferation and induce apoptosis of LNCaP cells.

Romero I, Páez A, Ferruelo A, Luján M, Berenguer A.

BJU Int. 2002 Jun;89(9):950-4.

35.

Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription.

Suárez Y, Fernández C, Ledo B, Ferruelo AJ, Martín M, Vega MA, Gómez-Coronado D, Lasunción MA.

Eur J Biochem. 2002 Mar;269(6):1761-71.

36.

Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives.

Martínez-Botas J, Ferruelo AJ, Suárez Y, Fernández C, Gómez-Coronado D, Lasunción MA.

Biochim Biophys Acta. 2001 Jun 29;1532(3):185-94.

PMID:
11470239
37.

Hydroxymethylglutaryl-coenzyme A reductase inhibition stimulates caspase-1 activity and Th1-cytokine release in peripheral blood mononuclear cells.

Montero MT, Hernández O, Suárez Y, Matilla J, Ferruelo AJ, Martínez-Botas J, Gómez-Coronado D, Lasunción MA.

Atherosclerosis. 2000 Dec;153(2):303-13.

PMID:
11164419
38.

Detecting circulating prostate cells in patients with clinically localized prostate cancer: clinical implications for molecular staging.

Llanes L, Páez A, Ferruelo A, Luján M, Romero I, Berenguer A.

BJU Int. 2000 Dec;86(9):1023-7.

39.

Cholesterol starvation decreases p34(cdc2) kinase activity and arrests the cell cycle at G2.

Martínez-Botas J, Suárez Y, Ferruelo AJ, Gómez-Coronado D, Lasuncion MA.

FASEB J. 1999 Aug;13(11):1359-70.

PMID:
10428760
40.

Induction of apoptosis in p53-null HL-60 cells by inhibition of lanosterol 14-alpha demethylase.

Martínez-Botas J, Ferruelo AJ, Suárez Y, Gómez-Coronado D, Lasunción MA.

Biochimie. 1998 Nov;80(11):887-94.

PMID:
9893947

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