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Identification of CSPG4 as a promising target for translational combinatorial approaches in osteosarcoma.

Riccardo F, Tarone L, Iussich S, Giacobino D, Arigoni M, Sammartano F, Morello E, Martano M, Gattino F, Maria R, Ferrone S, Buracco P, Cavallo F.

Ther Adv Med Oncol. 2019 Jun 6;11:1758835919855491. doi: 10.1177/1758835919855491. eCollection 2019.


Unmasking of a primary desmoplastic melanoma tumour in the course of treatment of a metastatic disease with anti-PD-1 monoclonal antibody.

Richtig G, Ramelyte E, Koch L, Greinix H, Ferrone S, Dummer R, Richtig E.

J Eur Acad Dermatol Venereol. 2019 May 13. doi: 10.1111/jdv.15675. [Epub ahead of print] No abstract available.


Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing.

Tian T, Lv X, Pan G, Lu Y, Chen W, He W, Lei X, Zhang H, Liu M, Sun S, Ou Z, Lin X, Cai L, He L, Tu Z, Wang X, Tannous BA, Ferrone S, Li J, Fan S.

Clin Cancer Res. 2019 Jun 15;25(12):3673-3688. doi: 10.1158/1078-0432.CCR-18-2739. Epub 2019 Mar 18.


Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.

Sottile R, Federico G, Garofalo C, Tallerico R, Faniello MC, Quaresima B, Cristiani CM, Di Sanzo M, Cuda G, Ventura V, Wagner AK, Contrò G, Perrotti N, Gulletta E, Ferrone S, Kärre K, Costanzo FS, Carlomagno F, Carbone E.

Front Immunol. 2019 Feb 26;10:224. doi: 10.3389/fimmu.2019.00224. eCollection 2019.


B7-H3-targeted radioimmunotherapy of human cancer.

Kasten BB, Ferrone S, Zinn KR, Buchsbaum DJ.

Curr Med Chem. 2019 Feb 28. doi: 10.2174/0929867326666190228120908. [Epub ahead of print]


High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy.

Mitra D, Horick NK, Brackett DG, Mouw KW, Hornick JL, Ferrone S, Hong TS, Mamon H, Clark JW, Parikh AR, Allen JN, Ryan DP, Ting DT, Deshpande V, Wo JY.

Oncologist. 2019 Jun;24(6):e275-e283. doi: 10.1634/theoncologist.2018-0794. Epub 2019 Feb 12.


Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.

Du H, Hirabayashi K, Ahn S, Kren NP, Montgomery SA, Wang X, Tiruthani K, Mirlekar B, Michaud D, Greene K, Herrera SG, Xu Y, Sun C, Chen Y, Ma X, Ferrone CR, Pylayeva-Gupta Y, Yeh JJ, Liu R, Savoldo B, Ferrone S, Dotti G.

Cancer Cell. 2019 Feb 11;35(2):221-237.e8. doi: 10.1016/j.ccell.2019.01.002.


Role of Tumor-Associated Macrophages in the Clinical Course of Pancreatic Neuroendocrine Tumors (PanNETs).

Cai L, Michelakos T, Deshpande V, Arora KS, Yamada T, Ting DT, Taylor MS, Castillo CF, Warshaw AL, Lillemoe KD, Ferrone S, Ferrone CR.

Clin Cancer Res. 2019 Apr 15;25(8):2644-2655. doi: 10.1158/1078-0432.CCR-18-1401. Epub 2019 Jan 22.


Mitochondrial miRNA Determines Chemoresistance by Reprogramming Metabolism and Regulating Mitochondrial Transcription.

Fan S, Tian T, Chen W, Lv X, Lei X, Zhang H, Sun S, Cai L, Pan G, He L, Ou Z, Lin X, Wang X, Perez MF, Tu Z, Ferrone S, Tannous BA, Li J.

Cancer Res. 2019 Mar 15;79(6):1069-1084. doi: 10.1158/0008-5472.CAN-18-2505. Epub 2019 Jan 18.


Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy.

Maio M, Coukos G, Ferrone S, Fox BA, Fridman WH, Garcia PL, Lahn M, Provendier O, Russo V, Rüttinger D, Shalabi A, Trajanoski Z, Viallet J, Wolchok JD, Ibrahim R.

Cancer Immunol Immunother. 2019 Jan;68(1):1-9. doi: 10.1007/s00262-018-2285-y. Epub 2018 Dec 18.


Novel ANO5 mutation c.1067G>T (p.C356F) identified by whole genome sequencing in a big family with atypical gnathodiaphyseal dysplasia.

Zeng B, Liao J, Zhang H, Fu S, Chen W, Pan G, Li Q, Chen W, Ferrone S, Wu B, Sun S, Hu J, Ahn MH, Lin Z, Yu D, Ou Z, Wang X, Mo F, Huang N, Hamilton JA, Li J, Fan S.

Head Neck. 2019 Jan;41(1):230-238. doi: 10.1002/hed.25516. Epub 2018 Dec 15.


Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours.

Durgeau A, Virk Y, Gros G, Voilin E, Corgnac S, Djenidi F, Salmon J, Adam J, de Montpréville V, Validire P, Ferrone S, Chouaib S, Eggermont A, Soria JC, Lemonnier F, Tartour E, Chaput N, Besse B, Mami-Chouaib F.

Nat Commun. 2018 Nov 30;9(1):5097. doi: 10.1038/s41467-018-07603-1.


Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature.

Sabbatino F, Marra A, Liguori L, Scognamiglio G, Fusciello C, Botti G, Ferrone S, Pepe S.

J Immunother Cancer. 2018 Nov 20;6(1):126. doi: 10.1186/s40425-018-0439-2.


Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(-) Head and Neck Cancer Cell Lines.

Ludwig S, Sharma P, Theodoraki MN, Pietrowska M, Yerneni SS, Lang S, Ferrone S, Whiteside TL.

Front Oncol. 2018 Oct 12;8:445. doi: 10.3389/fonc.2018.00445. eCollection 2018.


Significance of the intraindividual variability of HLA IgG antibodies in renal disease patients observed with different beadsets monitored with two different secondary antibodies on a Luminex platform.

Ravindranath MH, Filippone EJ, Mahowald G, Callender C, Babu A, Saidman S, Ferrone S.

Immunol Res. 2018 Oct;66(5):584-604. doi: 10.1007/s12026-018-9027-2.


The role of cancer stem cells in the modulation of anti-tumor immune responses.

Maccalli C, Rasul KI, Elawad M, Ferrone S.

Semin Cancer Biol. 2018 Dec;53:189-200. doi: 10.1016/j.semcancer.2018.09.006. Epub 2018 Sep 24. Review.


Water, Ions, and Hemoglobin: Effects on Allostery and Polymerization.

Rotter MA, Jiang J, Ferrone SM, Ferrone FA.

J Phys Chem B. 2018 Dec 13;122(49):11591-11597. doi: 10.1021/acs.jpcb.8b07630. Epub 2018 Oct 4.


Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy).

Ascierto PA, Puzanov I, Agarwala SS, Bifulco C, Botti G, Caracò C, Ciliberto G, Davies MA, Dummer R, Ferrone S, Gajewski TF, Garbe C, Luke JJ, Marincola FM, Masucci G, Mehnert JM, Mozzillo N, Palmieri G, Postow MA, Schoenberger SP, Wang E, Thurin M.

J Transl Med. 2018 Jul 21;16(1):207. doi: 10.1186/s12967-018-1568-6.


Risk Prediction Model for Cisplatin-Associated Acute Kidney Injury.

Kurokawa T, Tsurita G, Tanimoto T, Yamada T, Ferrone S.

J Clin Oncol. 2018 Aug 10;36(23):2453-2454. doi: 10.1200/JCO.2018.77.8761. Epub 2018 Jun 29. No abstract available.


Acute and long-lasting cortical thickness changes following intensive first-person action videogame practice.

Momi D, Smeralda C, Sprugnoli G, Ferrone S, Rossi S, Rossi A, Di Lorenzo G, Santarnecchi E.

Behav Brain Res. 2018 Nov 1;353:62-73. doi: 10.1016/j.bbr.2018.06.013. Epub 2018 Jun 23.


Methods for improving the immunogenicity and efficacy of cancer vaccines.

Pilla L, Ferrone S, Maccalli C.

Expert Opin Biol Ther. 2018 Jul;18(7):765-784. doi: 10.1080/14712598.2018.1485649. Epub 2018 Jun 17. Review.


Age of Insomnia Onset Correlates with a Reversal of Default Mode Network and Supplementary Motor Cortex Connectivity.

Santarnecchi E, Del Bianco C, Sicilia I, Momi D, Di Lorenzo G, Ferrone S, Sprugnoli G, Rossi S, Rossi A.

Neural Plast. 2018 Apr 1;2018:3678534. doi: 10.1155/2018/3678534. eCollection 2018.


Corrigendum to '212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models' [Nucl Med Biol 58 (2018) 67-73].

Kasten BB, Gangrade A, Kim H, Fan J, Ferrone S, Ferrone CR, Zinn KR, Buchsbaum DJ.

Nucl Med Biol. 2018 Jun;61:71. doi: 10.1016/j.nucmedbio.2018.03.004. Epub 2018 Apr 25. No abstract available.


Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins.

Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK.

Photochem Photobiol Sci. 2018 May 16;17(5):539-551. doi: 10.1039/C7PP00358G.


212Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models.

Kasten BB, Oliver PG, Kim H, Fan J, Ferrone S, Zinn KR, Buchsbaum DJ.

Int J Mol Sci. 2018 Mar 21;19(4). pii: E925. doi: 10.3390/ijms19040925.


Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma.

Sharma P, Ludwig S, Muller L, Hong CS, Kirkwood JM, Ferrone S, Whiteside TL.

J Extracell Vesicles. 2018 Feb 15;7(1):1435138. doi: 10.1080/20013078.2018.1435138. eCollection 2018.


Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy.

Pellegatta S, Savoldo B, Di Ianni N, Corbetta C, Chen Y, Patané M, Sun C, Pollo B, Ferrone S, DiMeco F, Finocchiaro G, Dotti G.

Sci Transl Med. 2018 Feb 28;10(430). pii: eaao2731. doi: 10.1126/scitranslmed.aao2731. Erratum in: Sci Transl Med. 2018 Apr 4;10 (435):.


Defective HLA class I antigen processing machinery in cancer.

Cai L, Michelakos T, Yamada T, Fan S, Wang X, Schwab JH, Ferrone CR, Ferrone S.

Cancer Immunol Immunother. 2018 Jun;67(6):999-1009. doi: 10.1007/s00262-018-2131-2. Epub 2018 Feb 27.


212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models.

Kasten BB, Gangrade A, Kim H, Fan J, Ferrone S, Ferrone CR, Zinn KR, Buchsbaum DJ.

Nucl Med Biol. 2018 Mar;58:67-73. doi: 10.1016/j.nucmedbio.2017.12.004. Epub 2017 Dec 24. Erratum in: Nucl Med Biol. 2018 Apr 25;:.


Overexpression of miR-489 enhances efficacy of 5-fluorouracil-based treatment in breast cancer stem cells by targeting XIAP.

Wang X, Wang X, Gu J, Zhou M, He Z, Wang X, Ferrone S.

Oncotarget. 2017 Dec 6;8(69):113837-113846. doi: 10.18632/oncotarget.22985. eCollection 2017 Dec 26.


HLA class I antigen processing machinery (APM) component expression and PD-1:PD-L1 pathway activation in HIV-infected head and neck cancers.

Pai SI, Jack Lee J, Carey TE, Westra WH, Ferrone S, Moore C, Mosunjac MB, Shin DM, Ferris RL; HNC SPORE HIV supplement consortium.

Oral Oncol. 2018 Feb;77:92-97. doi: 10.1016/j.oraloncology.2017.12.014. Epub 2017 Dec 28.


Translational Research in Cutaneous Melanoma: New Therapeutic Perspectives.

Marra A, Ferrone CR, Fusciello C, Scognamiglio G, Ferrone S, Pepe S, Perri F, Sabbatino F.

Anticancer Agents Med Chem. 2018;18(2):166-181. doi: 10.2174/1871520618666171219115335.


Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016.

Ascierto PA, Agarwala SS, Ciliberto G, Demaria S, Dummer R, Duong CPM, Ferrone S, Formenti SC, Garbe C, Halaban R, Khleif S, Luke JJ, Mir LM, Overwijk WW, Postow M, Puzanov I, Sondel P, Taube JM, Thor Straten P, Stroncek DF, Wargo JA, Zarour H, Thurin M.

J Transl Med. 2017 Nov 16;15(1):236. doi: 10.1186/s12967-017-1341-2.


Innovative Therapy, Monoclonal Antibodies and Beyond.

Di Nicola M, Apetoh L, Bellone M, Colombo MP, Dotti G, Ferrone S, Muscolini M, Hiscott J, Anichini A, Pupa SM, Braud F, Del Vecchio M.

Cytokine Growth Factor Rev. 2017 Dec;38:1-9. doi: 10.1016/j.cytogfr.2017.10.002. Epub 2017 Oct 5.


Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer.

Gettinger S, Choi J, Hastings K, Truini A, Datar I, Sowell R, Wurtz A, Dong W, Cai G, Melnick MA, Du VY, Schlessinger J, Goldberg SB, Chiang A, Sanmamed MF, Melero I, Agorreta J, Montuenga LM, Lifton R, Ferrone S, Kavathas P, Rimm DL, Kaech SM, Schalper K, Herbst RS, Politi K.

Cancer Discov. 2017 Dec;7(12):1420-1435. doi: 10.1158/2159-8290.CD-17-0593. Epub 2017 Oct 12.


The Humoral Theory of Transplantation.

Ravindranath MH, Cai J, Ferrone S, Claas FHJ, Selvan SR.

J Immunol Res. 2017;2017:5935123. doi: 10.1155/2017/5935123. Epub 2017 Aug 8. No abstract available.


High Antigen Processing Machinery component expression in Langerhans cells from melanoma patients' sentinel lymph nodes.

Romoli MR, Di Gennaro P, Gerlini G, Sestini S, Brandani P, Ferrone S, Borgognoni L.

Cell Immunol. 2017 Oct;320:29-37. doi: 10.1016/j.cellimm.2017.08.007. Epub 2017 Aug 30.


A novel chemoradiation targeting stem and nonstem pancreatic cancer cells by repurposing disulfiram.

Cong J, Wang Y, Zhang X, Zhang N, Liu L, Soukup K, Michelakos T, Hong T, DeLeo A, Cai L, Sabbatino F, Ferrone S, Lee H, Levina V, Fuchs B, Tanabe K, Lillemoe K, Ferrone C, Wang X.

Cancer Lett. 2017 Nov 28;409:9-19. doi: 10.1016/j.canlet.2017.08.028. Epub 2017 Aug 30.


ADAM12-L confers acquired 5-fluorouracil resistance in breast cancer cells.

Wang X, Wang Y, Gu J, Zhou D, He Z, Wang X, Ferrone S.

Sci Rep. 2017 Aug 29;7(1):9687. doi: 10.1038/s41598-017-10468-x.


Monitoring native HLA-I trimer specific antibodies in Luminex multiplex single antigen bead assay: Evaluation of beadsets from different manufacturers.

Ravindranath MH, Jucaud V, Ferrone S.

J Immunol Methods. 2017 Nov;450:73-80. doi: 10.1016/j.jim.2017.07.016. Epub 2017 Aug 4. Erratum in: J Immunol Methods. 2018 Sep;460:125.


Immune Surveillance Plays a Role in Locally Aggressive Giant Cell Lesions of Bone.

Al-Sukaini A, Hornicek FJ, Peacock ZS, Kaban LB, Ferrone S, Schwab JH.

Clin Orthop Relat Res. 2017 Dec;475(12):3071-3081. doi: 10.1007/s11999-017-5451-1. Epub 2017 Jul 19.


Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy.

Yang KS, Im H, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R.

Sci Transl Med. 2017 May 24;9(391). pii: eaal3226. doi: 10.1126/scitranslmed.aal3226.


Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma.

Ritter C, Fan K, Paschen A, Reker Hardrup S, Ferrone S, Nghiem P, Ugurel S, Schrama D, Becker JC.

Sci Rep. 2017 May 23;7(1):2290. doi: 10.1038/s41598-017-02608-0.


FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance.

Caratelli S, Sconocchia T, Arriga R, Coppola A, Lanzilli G, Lauro D, Venditti A, Del Principe MI, Buccisano F, Maurillo L, Ferrone S, Sconocchia G.

Front Immunol. 2017 Apr 27;8:457. doi: 10.3389/fimmu.2017.00457. eCollection 2017. Review.


Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma.

Cai L, Michelakos T, Ferrone CR, Zhang L, Deshpande V, Shen Q, DeLeo A, Yamada T, Zhang G, Ferrone S, Wang X.

Oncotarget. 2017 Jun 6;8(23):37646-37656. doi: 10.18632/oncotarget.16841.


HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance.

Seliger B, Kloor M, Ferrone S.

Oncoimmunology. 2017 Feb 6;6(2):e1171447. doi: 10.1080/2162402X.2016.1171447. eCollection 2017. Review.


Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy.

Maccalli C, Parmiani G, Ferrone S.

Immunol Invest. 2017 Apr;46(3):221-238. doi: 10.1080/08820139.2017.1280051. Epub 2017 Mar 13. Review.


B7-H3-targeted 212Pb radioimmunotherapy of ovarian cancer in preclinical models.

Kasten BB, Arend RC, Katre AA, Kim H, Fan J, Ferrone S, Zinn KR, Buchsbaum DJ.

Nucl Med Biol. 2017 Apr;47:23-30. doi: 10.1016/j.nucmedbio.2017.01.003. Epub 2017 Jan 10.


Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.

Ascierto PA, Agarwala S, Botti G, Cesano A, Ciliberto G, Davies MA, Demaria S, Dummer R, Eggermont AM, Ferrone S, Fu YX, Gajewski TF, Garbe C, Huber V, Khleif S, Krauthammer M, Lo RS, Masucci G, Palmieri G, Postow M, Puzanov I, Silk A, Spranger S, Stroncek DF, Tarhini A, Taube JM, Testori A, Wang E, Wargo JA, Yee C, Zarour H, Zitvogel L, Fox BA, Mozzillo N, Marincola FM, Thurin M.

J Transl Med. 2016 Nov 15;14(1):313.

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