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Items: 29


Influenza A virus protein NS1 exhibits strain-independent conformational plasticity.

Mitra S, Kumar D, Hu L, Sankaran B, Moosa MM, Rice AP, Ferreon JC, Ferreon ACM, Prasad BVV.

J Virol. 2019 Aug 2. pii: JVI.00917-19. doi: 10.1128/JVI.00917-19. [Epub ahead of print]


Single-Molecule FRET Detection of Early-Stage Conformations in α-Synuclein Aggregation.

Moosa MM, Ferreon JC, Ferreon ACM.

Methods Mol Biol. 2019;1948:221-233. doi: 10.1007/978-1-4939-9124-2_17.


A Chemical Chaperone Decouples TDP-43 Disordered Domain Phase Separation from Fibrillation.

Choi KJ, Tsoi PS, Moosa MM, Paulucci-Holthauzen A, Liao SJ, Ferreon JC, Ferreon ACM.

Biochemistry. 2018 Dec 18;57(50):6822-6826. doi: 10.1021/acs.biochem.8b01051. Epub 2018 Dec 10.


Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box.

Moosa MM, Tsoi PS, Choi KJ, Ferreon ACM, Ferreon JC.

Int J Mol Sci. 2018 Dec 4;19(12). pii: E3865. doi: 10.3390/ijms19123865.


Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection.

Ramani S, Stewart CJ, Laucirica DR, Ajami NJ, Robertson B, Autran CA, Shinge D, Rani S, Anandan S, Hu L, Ferreon JC, Kuruvilla KA, Petrosino JF, Venkataram Prasad BV, Bode L, Kang G, Estes MK.

Nat Commun. 2018 Nov 27;9(1):5010. doi: 10.1038/s41467-018-07476-4.


Glycan recognition in globally dominant human rotaviruses.

Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV.

Nat Commun. 2018 Jul 6;9(1):2631. doi: 10.1038/s41467-018-05098-4.


Ligand interactions and the protein order-disorder energetic continuum.

Moosa MM, Ferreon JC, Ferreon ACM.

Semin Cell Dev Biol. 2018 May 12. pii: S1084-9521(17)30391-9. doi: 10.1016/j.semcdb.2018.05.007. [Epub ahead of print] Review.


Acetylation Disfavors Tau Phase Separation.

Ferreon JC, Jain A, Choi KJ, Tsoi PS, MacKenzie KR, Jung SY, Ferreon AC.

Int J Mol Sci. 2018 May 4;19(5). pii: E1360. doi: 10.3390/ijms19051360.


Denaturant-specific effects on the structural energetics of a protein-denatured ensemble.

Moosa MM, Goodman AZ, Ferreon JC, Lee CW, Ferreon ACM, Deniz AA.

Eur Biophys J. 2018 Jan;47(1):89-94. doi: 10.1007/s00249-017-1260-4. Epub 2017 Oct 27.


The N-Terminal Domain of ALS-Linked TDP-43 Assembles without Misfolding.

Tsoi PS, Choi KJ, Leonard PG, Sizovs A, Moosa MM, MacKenzie KR, Ferreon JC, Ferreon ACM.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12590-12593. doi: 10.1002/anie.201706769. Epub 2017 Sep 5.


Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.

Krois AS, Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1853-62. doi: 10.1073/pnas.1602487113. Epub 2016 Mar 14.


Modulation of allostery by protein intrinsic disorder.

Ferreon AC, Ferreon JC, Wright PE, Deniz AA.

Nature. 2013 Jun 20;498(7454):390-4. doi: 10.1038/nature12294.


Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation.

Lee CW, Ferreon JC, Ferreon AC, Arai M, Wright PE.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19290-5. doi: 10.1073/pnas.1013078107. Epub 2010 Oct 20.


Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease.

Ferreon AC, Moran CR, Ferreon JC, Deniz AA.

Angew Chem Int Ed Engl. 2010 May 3;49(20):3469-72. doi: 10.1002/anie.201000378. No abstract available.


Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.

Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13260-5. doi: 10.1073/pnas.0906770106. Epub 2009 Jul 27.


Characterizing the role of ensemble modulation in mutation-induced changes in binding affinity.

Manson A, Whitten ST, Ferreon JC, Fox RO, Hilser VJ.

J Am Chem Soc. 2009 May 20;131(19):6785-93. doi: 10.1021/ja809133u.


Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2.

Ferreon JC, Lee CW, Arai M, Martinez-Yamout MA, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6591-6. doi: 10.1073/pnas.0811023106. Epub 2009 Apr 8.


Protein phase diagrams II: nonideal behavior of biochemical reactions in the presence of osmolytes.

Ferreon AC, Ferreon JC, Bolen DW, Rösgen J.

Biophys J. 2007 Jan 1;92(1):245-56. Epub 2006 Oct 6.


Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease.

Ferreon JC, Ferreon AC, Li K, Lemon SM.

J Biol Chem. 2005 May 27;280(21):20483-92. Epub 2005 Mar 14.


Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF.

Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr, Lemon SM.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2992-7. Epub 2005 Feb 14.


Thermodynamic mechanism and consequences of the polyproline II (PII) structural bias in the denatured states of proteins.

Hamburger JB, Ferreon JC, Whitten ST, Hilser VJ.

Biochemistry. 2004 Aug 3;43(30):9790-9.


Directed discovery of bivalent peptide ligands to an SH3 domain.

Ferguson MR, Fan X, Mukherjee M, Luo J, Khan R, Ferreon JC, Hilser VJ, Shope RE, Fox RO.

Protein Sci. 2004 Mar;13(3):626-32.


Solution structure, dynamics, and thermodynamics of the native state ensemble of the Sem-5 C-terminal SH3 domain.

Ferreon JC, Volk DE, Luxon BA, Gorenstein DG, Hilser VJ.

Biochemistry. 2003 May 20;42(19):5582-91.


Homology modeling and characterization of IgE binding epitopes of mountain cedar allergen Jun a 3.

Soman KV, Midoro-Horiuti T, Ferreon JC, Goldblum RM, Brooks EG, Kurosky A, Braun W, Schein CH.

Biophys J. 2000 Sep;79(3):1601-9.

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