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Items: 1 to 50 of 137

1.

What you see is not what you get: believing patient-reported seizure counts.

Kalamangalam GP, Slater JD, Ferrendelli JA.

Arch Neurol. 2007 Nov;64(11):1565-6. No abstract available.

PMID:
17998438
2.

Enantioselectivity of alpha-benzyl-alpha-methyl-gamma-butyrolactone-mediated modulation of anticonvulsant activity and GABA(A) receptor function.

Gonzales EB, Bell-Horner CL, de la Cruz MA, Ferrendelli JA, Covey DF, Dillon GH.

J Pharmacol Exp Ther. 2004 May;309(2):677-83. Epub 2004 Jan 23.

PMID:
14742738
3.

Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial.

Ferrendelli JA, French J, Leppik I, Morrell MJ, Herbeuval A, Han J, Magnus L.

Epilepsy Behav. 2003 Dec;4(6):702-9.

PMID:
14698704
4.

Concerns with antiepileptic drug initiation: safety, tolerability, and efficacy.

Ferrendelli JA.

Epilepsia. 2001;42 Suppl 4:28-30. Review.

5.

Pharmacology of antiepileptic drug polypharmacy.

Ferrendelli JA.

Epilepsia. 1999;40 Suppl 5:S81-3.

6.

Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function.

Canney DJ, Lu HF, McKeon AC, Yoon KW, Xu K, Holland KD, Rothman SM, Ferrendelli JA, Covey DF.

Bioorg Med Chem. 1998 Jan;6(1):43-55.

PMID:
9502104
7.

Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.

Williams KL, Tucker JB, White G, Weiss DS, Ferrendelli JA, Covey DF, Krause JE, Rothman SM.

Mol Pharmacol. 1997 Jul;52(1):114-9.

PMID:
9224820
8.

Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones.

Gross RA, Covey DF, Ferrendelli JA.

J Pharmacol Exp Ther. 1997 Feb;280(2):686-94.

PMID:
9023280
9.

Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams).

Reddy PA, Woodward KE, McIlheran SM, Hsiang BC, Latifi TN, Hill MW, Rothman SM, Ferrendelli JA, Covey DF.

J Med Chem. 1997 Jan 3;40(1):44-9.

PMID:
9016327
10.

3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: a new class of anticonvulsant agents.

Reddy PA, Hsiang BC, Latifi TN, Hill MW, Woodward KE, Rothman SM, Ferrendelli JA, Covey DF.

J Med Chem. 1996 Apr 26;39(9):1898-906.

PMID:
8627613
11.

Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors.

Mathews GC, Bolos-Sy AM, Covey DF, Rothman SM, Ferrendelli JA.

Neuropharmacology. 1996 Feb;35(2):123-36.

PMID:
8734480
12.

Use of rational polypharmacy to treat epilepsy.

Ferrendelli JA.

Epilepsy Res Suppl. 1996;11:239-43. Review. No abstract available.

PMID:
9294741
13.

Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones.

Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM.

Mol Pharmacol. 1995 Jun;47(6):1217-23.

PMID:
7603463
14.

Relating pharmacology to clinical practice: the pharmacologic basis of rational polypharmacy.

Ferrendelli JA.

Neurology. 1995 Mar;45(3 Suppl 2):S12-6. Review.

PMID:
7898740
15.

Rational polypharmacy.

Ferrendelli JA.

Epilepsia. 1995;36 Suppl 2:S115-8. Review.

PMID:
8784220
16.

Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons.

Mathews GC, Bolos-Sy AM, Holland KD, Isenberg KE, Covey DF, Ferrendelli JA, Rothman SM.

Neuron. 1994 Jul;13(1):149-58.

PMID:
8043274
17.
18.
19.

Relative anticonvulsant effects of GABAmimetic and GABA modulatory agents.

Holland KD, McKeon AC, Canney DJ, Covey DF, Ferrendelli JA.

Epilepsia. 1992 Nov-Dec;33(6):981-6.

PMID:
1334454
20.

Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.

Canney DJ, Holland KD, Levine JA, McKeon AC, Ferrendelli JA, Covey DF.

J Med Chem. 1991 Apr;34(4):1460-7.

PMID:
1849999
21.

Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist.

Holland KD, Yoon KW, Ferrendelli JA, Covey DF, Rothman SM.

Mol Pharmacol. 1991 Jan;39(1):79-84.

PMID:
1846222
22.

Electroencephalographic effects of intracisternally injected nonionic x-ray contrast media in rats.

Adams MD, Ralston WH, Miller JW, Ferrendelli JA.

Invest Radiol. 1990 Sep;25 Suppl 1:S86-7. No abstract available.

PMID:
2283269
23.

Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.

Holland KD, McKeon AC, Covey DF, Ferrendelli JA.

J Pharmacol Exp Ther. 1990 Aug;254(2):578-83.

PMID:
2166797
24.

Characterization of GABAergic seizure regulation in the midline thalamus.

Miller JW, Ferrendelli JA.

Neuropharmacology. 1990 Jul;29(7):649-55.

PMID:
2166925
25.
26.

Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons.

Holland KD, Canney DJ, Rothman SM, Ferrendelli JA, Covey DF.

Brain Res. 1990 May 14;516(1):147-50.

PMID:
2163720
27.
28.

The central medial nucleus: thalamic site of seizure regulation.

Miller JW, Ferrendelli JA.

Brain Res. 1990 Feb 5;508(2):297-300.

PMID:
2306621
29.

Use of nonradioactive 2-deoxyglucose to study compartmentation of brain glucose metabolism and rapid regional changes in rate.

McDougal DB Jr, Ferrendelli JA, Yip V, Pusateri ME, Carter JG, Chi MM, Norris B, Manchester J, Lowry OH.

Proc Natl Acad Sci U S A. 1990 Feb;87(4):1357-61.

30.

Regulation of cyclic AMP levels in mammalian retina: Effects of depolarizing agents and transmitters.

Blazynski C, Devries G, Geary K, Cohen AI, Ferrendelli JA.

Neurochem Int. 1990;17(3):425-33.

PMID:
20504642
31.

Convulsant and anticonvulsant cyclopentanones and cyclohexanones.

Holland KD, Naritoku DK, McKeon AC, Ferrendelli JA, Covey DF.

Mol Pharmacol. 1990 Jan;37(1):98-103.

PMID:
2153913
32.

Comparison of the anticonvulsant activities of ethosuximide, valproate, and a new anticonvulsant, thiobutyrolactone.

Ferrendelli JA, Holland KD, McKeon AC, Covey DF.

Epilepsia. 1989 Sep-Oct;30(5):617-22.

PMID:
2507307
33.

Identification of a median thalamic system regulating seizures and arousal.

Miller JW, Hall CM, Holland KD, Ferrendelli JA.

Epilepsia. 1989 Jul-Aug;30(4):493-500.

PMID:
2753001
34.

A rat EEG model for evaluating contrast media neurotoxicity.

Adams MD, Hopkins RM, Ferrendelli JA.

Invest Radiol. 1988 Sep;23 Suppl 1:S217-9.

PMID:
3198347
35.

Functional anatomy of pentylenetetrazol and electroshock seizures in the rat brainstem.

Miller JW, McKeon AC, Ferrendelli JA.

Ann Neurol. 1987 Nov;22(5):615-21.

PMID:
3426167
36.

Phenytoin and carbamazepine, alone and in combination: anticonvulsant and neurotoxic effects.

Morris JC, Dodson WE, Hatlelid JM, Ferrendelli JA.

Neurology. 1987 Jul;37(7):1111-8.

PMID:
3601077
37.

Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.

Naritoku DK, Levine JA, Covey DF, Ferrendelli JA.

Biochem Pharmacol. 1987 Mar 15;36(6):797-800. No abstract available.

PMID:
3566782
39.

Lennox-Gastaut syndrome and positron emission tomography.

Ferrendelli JA.

Ann Neurol. 1987 Jan;21(1):3. No abstract available.

PMID:
3103527
40.

Pharmacology of antiepileptic drugs.

Ferrendelli JA.

Epilepsia. 1987;28 Suppl 3:S14-6.

PMID:
2446860
41.

Anterior thalamic mediation of generalized pentylenetetrazol seizures.

Mirski MA, Ferrendelli JA.

Brain Res. 1986 Dec 10;399(2):212-23.

PMID:
3548879
42.

Anterior thalamus and substantia nigra: two distinct structures mediating experimental generalized seizures.

Mirski MA, McKeon AC, Ferrendelli JA.

Brain Res. 1986 Nov 12;397(2):377-80.

PMID:
3801876
43.
45.

Adenosine-mediated regulation of cyclic AMP levels in isolated incubated retinas.

Blazynski C, Kinscherf DA, Geary KM, Ferrendelli JA.

Brain Res. 1986 Feb 26;366(1-2):224-9.

PMID:
2421821
46.

Roles of biogenic amines and cyclic nucleotides in seizure mechanisms.

Ferrendelli JA.

Adv Neurol. 1986;44:393-400. No abstract available.

PMID:
3706017
47.

Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/T-butylbicyclophosphorothionate (TBPS) receptor.

Levine JA, Ferrendelli JA, Covey DF.

Biochem Pharmacol. 1985 Dec 1;34(23):4187-90. No abstract available.

PMID:
2998401
48.

Indoleamine-sensitive adenylate cyclase in rabbit retina: characterization and distribution.

Blazynski C, Ferrendelli JA, Cohen AI.

J Neurochem. 1985 Aug;45(2):440-7.

PMID:
2409230
49.

Interruption of the mammillothalamic tract prevents seizures in guinea pigs.

Mirski MA, Ferrendelli JA.

Science. 1984 Oct 5;226(4670):72-4.

PMID:
6433485
50.

Regulatory effects of neurotransmitters on electroshock and pentylenetetrazol seizures.

Burley ES, Ferrendelli JA.

Fed Proc. 1984 Jul;43(10):2521-4.

PMID:
6145628

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