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Items: 1 to 50 of 163

1.

Tumor-specific delivery of gemcitabine with activatable liposomes.

Tucci ST, Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Foiret J, Hubbard NE, Borowsky AD, Baikoghli M, Cheng RH, Ferrara KW.

J Control Release. 2019 Jul 10. pii: S0168-3659(19)30401-8. doi: 10.1016/j.jconrel.2019.07.014. [Epub ahead of print]

PMID:
31301340
2.

Acoustic radiation force imaging using a single-shot spiral readout.

Ilovitsh A, Fite BZ, Ilovitsh T, Ferrara KW.

Phys Med Biol. 2019 Jun 10;64(12):125004. doi: 10.1088/1361-6560/ab1e21.

PMID:
31039549
3.

Combining activatable nanodelivery with immunotherapy in a murine breast cancer model.

Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Ferrara KW.

J Control Release. 2019 Jun 10;303:42-54. doi: 10.1016/j.jconrel.2019.04.008. Epub 2019 Apr 9.

PMID:
30978432
4.

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen F.

Acta Neuropathol Commun. 2019 Apr 10;7(1):55. doi: 10.1186/s40478-019-0712-8.

5.

Polymeric perfluorocarbon nanoemulsions are ultrasound-activated wireless drug infusion catheters.

Zhong Q, Yoon BC, Aryal M, Wang JB, Ilovitsh T, Baikoghli MA, Hosseini-Nassab N, Karthik A, Cheng RH, Ferrara KW, Airan RD.

Biomaterials. 2019 Jun;206:73-86. doi: 10.1016/j.biomaterials.2019.03.021. Epub 2019 Mar 20.

PMID:
30953907
6.

Nonviral ultrasound-mediated gene delivery in small and large animal models.

Bez M, Foiret J, Shapiro G, Pelled G, Ferrara KW, Gazit D.

Nat Protoc. 2019 Apr;14(4):1015-1026. doi: 10.1038/s41596-019-0125-y. Epub 2019 Feb 25.

PMID:
30804568
7.

Simultaneous Axial Multifocal Imaging Using a Single Acoustical Transmission: A Practical Implementation.

Ilovitsh A, Ilovitsh T, Foiret J, Stephens DN, Ferrara KW.

IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Feb;66(2):273-284. doi: 10.1109/TUFFC.2018.2885080. Epub 2018 Dec 5.

PMID:
30530361
8.

Enhanced microbubble contrast agent oscillation following 250 kHz insonation.

Ilovitsh T, Ilovitsh A, Foiret J, Caskey CF, Kusunose J, Fite BZ, Zhang H, Mahakian LM, Tam S, Butts-Pauly K, Qin S, Ferrara KW.

Sci Rep. 2018 Nov 5;8(1):16347. doi: 10.1038/s41598-018-34494-5.

9.

A Scalable Method for Squalenoylation and Assembly of Multifunctional 64Cu-Labeled Squalenoylated Gemcitabine Nanoparticles.

Tucci ST, Seo JW, Kakwere H, Kheirolomoom A, Ingham ES, Mahakian LM, Tam S, Tumbale S, Baikoghli M, Cheng RH, Ferrara KW.

Nanotheranostics. 2018 Sep 5;2(4):387-402. doi: 10.7150/ntno.26969. eCollection 2018.

10.

Unimicellar hyperstars as multi-antigen cancer nanovaccines displaying clustered epitopes of immunostimulating peptides.

Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS, Ferrara KW.

Biomater Sci. 2018 Nov 1;6(11):2850-2858. doi: 10.1039/c8bm00891d. Epub 2018 Sep 19.

PMID:
30229768
11.

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation.

Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW.

Theranostics. 2018 Jun 7;8(13):3611-3628. doi: 10.7150/thno.25613. eCollection 2018.

12.

CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols.

Seo JW, Tavaré R, Mahakian LM, Silvestrini MT, Tam S, Ingham ES, Salazar FB, Borowsky AD, Wu AM, Ferrara KW.

Clin Cancer Res. 2018 Oct 15;24(20):4976-4987. doi: 10.1158/1078-0432.CCR-18-0261. Epub 2018 Jul 2.

PMID:
29967252
13.

Acoustical structured illumination for super-resolution ultrasound imaging.

Ilovitsh T, Ilovitsh A, Foiret J, Fite BZ, Ferrara KW.

Commun Biol. 2018;1. pii: 3. doi: 10.1038/s42003-017-0003-5. Epub 2018 Jan 22.

14.

Ultrasound-Mediated Gene Delivery Enhances Tendon Allograft Integration in Mini-Pig Ligament Reconstruction.

Bez M, Kremen TJ, Tawackoli W, Avalos P, Sheyn D, Shapiro G, Giaconi JC, Ben David S, Snedeker JG, Gazit Z, Ferrara KW, Gazit D, Pelled G.

Mol Ther. 2018 Jul 5;26(7):1746-1755. doi: 10.1016/j.ymthe.2018.04.020. Epub 2018 Apr 26.

15.

Imaging beyond ultrasonically-impenetrable objects.

Ilovitsh T, Ilovitsh A, Foiret J, Ferrara KW.

Sci Rep. 2018 Apr 10;8(1):5759. doi: 10.1038/s41598-018-23776-7.

16.

Ultrasound localization microscopy to image and assess microvasculature in a rat kidney.

Foiret J, Zhang H, Ilovitsh T, Mahakian L, Tam S, Ferrara KW.

Sci Rep. 2017 Oct 20;7(1):13662. doi: 10.1038/s41598-017-13676-7.

17.

Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.

Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS, Ferrara KW.

Bioconjug Chem. 2017 Nov 15;28(11):2756-2771. doi: 10.1021/acs.bioconjchem.7b00502. Epub 2017 Oct 13.

18.

In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.

Bez M, Sheyn D, Tawackoli W, Avalos P, Shapiro G, Giaconi JC, Da X, David SB, Gavrity J, Awad HA, Bae HW, Ley EJ, Kremen TJ, Gazit Z, Ferrara KW, Pelled G, Gazit D.

Sci Transl Med. 2017 May 17;9(390). pii: eaal3128. doi: 10.1126/scitranslmed.aal3128.

19.

Anatomical image-guided fluorescence molecular tomography reconstruction using kernel method.

Baikejiang R, Zhao Y, Fite BZ, Ferrara KW, Li C.

J Biomed Opt. 2017 May 1;22(5):55001. doi: 10.1117/1.JBO.22.5.055001.

20.

Supersonic transient magnetic resonance elastography for quantitative assessment of tissue elasticity.

Liu Y, Liu J, Fite BZ, Foiret J, Ilovitsh A, Leach JK, Dumont E, Caskey CF, Ferrara KW.

Phys Med Biol. 2017 May 21;62(10):4083-4106. doi: 10.1088/1361-6560/aa6674. Epub 2017 Apr 20.

21.

Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin.

Fite BZ, Kheirolomoom A, Foiret JL, Seo JW, Mahakian LM, Ingham ES, Tam SM, Borowsky AD, Curry FE, Ferrara KW.

J Control Release. 2017 Jun 28;256:203-213. doi: 10.1016/j.jconrel.2017.04.007. Epub 2017 Apr 7.

22.

Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW.

JCI Insight. 2017 Mar 23;2(6):e90521. doi: 10.1172/jci.insight.90521.

23.

Feasibility of quantitative contrast ultrasound imaging of bladder tumors in dogs.

Pollard RE, Watson KD, Hu X, Ingham E, Ferrara KW.

Can Vet J. 2017 Jan;58(1):70-72.

24.

In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles.

Zhang H, Ingham ES, Gagnon MK, Mahakian LM, Liu J, Foiret JL, Willmann JK, Ferrara KW.

Biomaterials. 2017 Feb;118:63-73. doi: 10.1016/j.biomaterials.2016.11.026. Epub 2016 Nov 21.

25.

Intracellular trafficking of a pH-responsive drug metal complex.

Kheirolomoom A, Ingham ES, Commisso J, Abushaban N, Ferrara KW.

J Control Release. 2016 Dec 10;243:232-242. doi: 10.1016/j.jconrel.2016.10.012. Epub 2016 Oct 13.

26.

Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer.

Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX.

Biomaterials. 2016 Oct;104:339-51. doi: 10.1016/j.biomaterials.2016.07.026. Epub 2016 Jul 22.

27.

Development of a spherically focused phased array transducer for ultrasonic image-guided hyperthermia.

Liu J, Foiret J, Stephens DN, Le Baron O, Ferrara KW.

Phys Med Biol. 2016 Jul 21;61(14):5275-96. doi: 10.1088/0031-9155/61/14/5275. Epub 2016 Jun 29.

28.

Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation.

Shapiro G, Wong AW, Bez M, Yang F, Tam S, Even L, Sheyn D, Ben-David S, Tawackoli W, Pelled G, Ferrara KW, Gazit D.

J Control Release. 2016 Feb 10;223:157-164. doi: 10.1016/j.jconrel.2015.12.001. Epub 2015 Dec 10.

29.

Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models.

Wong AW, Fite BZ, Liu Y, Kheirolomoom A, Seo JW, Watson KD, Mahakian LM, Tam SM, Zhang H, Foiret J, Borowsky AD, Ferrara KW.

J Clin Invest. 2016 Jan;126(1):99-111. doi: 10.1172/JCI83312. Epub 2015 Nov 23.

30.

CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.

Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW.

J Control Release. 2015 Dec 28;220(Pt A):253-264. doi: 10.1016/j.jconrel.2015.10.016. Epub 2015 Oct 22.

31.

Concurrent Visualization of Acoustic Radiation Force Displacement and Shear Wave Propagation with 7T MRI.

Liu Y, Fite BZ, Mahakian LM, Johnson SM, Larrat B, Dumont E, Ferrara KW.

PLoS One. 2015 Oct 6;10(10):e0139667. doi: 10.1371/journal.pone.0139667. eCollection 2015.

32.

Self-assembled 20-nm (64)Cu-micelles enhance accumulation in rat glioblastoma.

Seo JW, Ang J, Mahakian LM, Tam S, Fite B, Ingham ES, Beyer J, Forsayeth J, Bankiewicz KS, Xu T, Ferrara KW.

J Control Release. 2015 Dec 28;220(Pt A):51-60. doi: 10.1016/j.jconrel.2015.09.057. Epub 2015 Oct 5.

33.

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(-/-) Mice.

Kheirolomoom A, Kim CW, Seo JW, Kumar S, Son DJ, Gagnon MK, Ingham ES, Ferrara KW, Jo H.

ACS Nano. 2015 Sep 22;9(9):8885-97. doi: 10.1021/acsnano.5b02611. Epub 2015 Sep 2.

34.

Spatial and Temporal Control of Hyperthermia Using Real Time Ultrasonic Thermal Strain Imaging with Motion Compensation, Phantom Study.

Foiret J, Ferrara KW.

PLoS One. 2015 Aug 5;10(8):e0134938. doi: 10.1371/journal.pone.0134938. eCollection 2015.

35.

Ultrasound molecular imaging of tumor angiogenesis with a neuropilin-1-targeted microbubble.

Zhang H, Tam S, Ingham ES, Mahakian LM, Lai CY, Tumbale SK, Teesalu T, Hubbard NE, Borowsky AD, Ferrara KW.

Biomaterials. 2015 Jul;56:104-13. doi: 10.1016/j.biomaterials.2015.03.043. Epub 2015 Apr 16.

36.

Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound.

Fite BZ, Wong A, Liu Y, Mahakian LM, Tam SM, Aina O, Hubbard NE, Borowsky A, Cardiff RD, Dumont E, Ferrara KW.

PLoS One. 2015 Mar 18;10(3):e0120037. doi: 10.1371/journal.pone.0120037. eCollection 2015.

37.

The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model.

Seo JW, Mahakian LM, Tam S, Qin S, Ingham ES, Meares CF, Ferrara KW.

Nucl Med Biol. 2015 Feb;42(2):155-63. doi: 10.1016/j.nucmedbio.2014.09.001. Epub 2014 Sep 28.

38.

Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis.

Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11127-32. doi: 10.1073/pnas.1410432111. Epub 2014 Jul 14.

39.

ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer.

Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G.

Prostaglandins Other Lipid Mediat. 2014 Oct;113-115:13-20. doi: 10.1016/j.prostaglandins.2014.07.002. Epub 2014 Jul 11. Review.

40.

Effect of alkyl length of peptide-polymer amphiphile on cargo encapsulation stability and pharmacokinetics of 3-helix micelles.

Dube N, Seo JW, Dong H, Shu JY, Lund R, Mahakian LM, Ferrara KW, Xu T.

Biomacromolecules. 2014 Aug 11;15(8):2963-70. doi: 10.1021/bm5005788. Epub 2014 Jul 17.

41.

Albumin modulates S1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect.

Adamson RH, Clark JF, Radeva M, Kheirolomoom A, Ferrara KW, Curry FE.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1011-7. doi: 10.1152/ajpheart.00829.2013. Epub 2014 Feb 14. Erratum in: Am J Physiol Heart Circ Physiol. 2014 Jul 1;307(1):H120.

42.

Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes.

Paoli EE, Ingham ES, Zhang H, Mahakian LM, Fite BZ, Gagnon MK, Tam S, Kheirolomoom A, Cardiff RD, Ferrara KW.

J Control Release. 2014 Mar 28;178:108-17. doi: 10.1016/j.jconrel.2014.01.005. Epub 2014 Jan 13.

43.

(64)Cu-labeled LyP-1-dendrimer for PET-CT imaging of atherosclerotic plaque.

Seo JW, Baek H, Mahakian LM, Kusunose J, Hamzah J, Ruoslahti E, Ferrara KW.

Bioconjug Chem. 2014 Feb 19;25(2):231-9. doi: 10.1021/bc400347s. Epub 2014 Jan 31.

44.

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis.

Son DJ, Kumar S, Takabe W, Kim CW, Ni CW, Alberts-Grill N, Jang IH, Kim S, Kim W, Won Kang S, Baker AH, Woong Seo J, Ferrara KW, Jo H.

Nat Commun. 2013;4:3000. doi: 10.1038/ncomms4000.

45.

Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases.

Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham E, Caskey C, Sundstrøm T, Meade TJ, Harter PN, Skaftnesmo KO, Ferrara KW.

J Control Release. 2013 Dec 28;172(3):812-22. doi: 10.1016/j.jconrel.2013.10.019. Epub 2013 Oct 29.

46.

Creation and characterization of an ultrasound and CT phantom for noninvasive ultrasound thermometry calibration.

Chun-Yen Lai, Kruse DE, Ferrara KW, Caskey CF.

IEEE Trans Biomed Eng. 2014 Feb;61(2):502-12. doi: 10.1109/TBME.2013.2282775. Epub 2013 Sep 19.

47.

Quantitation of nanoparticle accumulation in flow using optimized microfluidic chambers.

Kusunose J, Gagnon MK, Seo JW, Ferrara KW.

J Drug Target. 2014 Jan;22(1):48-56. doi: 10.3109/1061186X.2013.837468. Epub 2013 Sep 30.

48.

Evaluation of doxorubicin-loaded 3-helix micelles as nanocarriers.

Dube N, Shu JY, Dong H, Seo JW, Ingham E, Kheirolomoom A, Chen PY, Forsayeth J, Bankiewicz K, Ferrara KW, Xu T.

Biomacromolecules. 2013 Oct 14;14(10):3697-705. doi: 10.1021/bm4010518. Epub 2013 Oct 3.

49.

Comparison of PET imaging with 64Cu-liposomes and 18F-FDG in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch model of oral dysplasia and squamous cell carcinoma.

Mahakian LM, Farwell DG, Zhang H, Seo JW, Poirier B, Tinling SP, Afify AM, Haynam EM, Shaye D, Ferrara KW.

Mol Imaging Biol. 2014 Apr;16(2):284-92. doi: 10.1007/s11307-013-0676-1.

50.

A physiological perspective on the use of imaging to assess the in vivo delivery of therapeutics.

Qin S, Fite BZ, Gagnon MK, Seo JW, Curry FR, Thorsen F, Ferrara KW.

Ann Biomed Eng. 2014 Feb;42(2):280-98. doi: 10.1007/s10439-013-0895-2. Epub 2013 Sep 10. Review.

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