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Items: 14


Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).

Wang L, Ferrao R, Li Q, Hatcher JM, Choi HG, Buhrlage SJ, Gray NS, Wu H.

J Biol Chem. 2019 Mar 22;294(12):4511-4519. doi: 10.1074/jbc.RA118.005428. Epub 2019 Jan 24.


Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.

Holliday MJ, Ferrao R, de Leon Boenig G, Estevez A, Helgason E, Rohou A, Dueber EC, Fairbrother WJ.

J Biol Chem. 2018 Oct 26;293(43):16803-16817. doi: 10.1074/jbc.RA118.004821. Epub 2018 Sep 11.


Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation.

Ferrao RD, Wallweber HJ, Lupardus PJ.

Elife. 2018 Jul 25;7. pii: e38089. doi: 10.7554/eLife.38089.


Accurate genomic prediction of Coffea canephora in multiple environments using whole-genome statistical models.

Ferrão LFV, Ferrão RG, Ferrão MAG, Fonseca A, Carbonetto P, Stephens M, Garcia AAF.

Heredity (Edinb). 2019 Mar;122(3):261-275. doi: 10.1038/s41437-018-0105-y. Epub 2018 Jun 25.


Crystal structure of human IRAK1.

Wang L, Qiao Q, Ferrao R, Shen C, Hatcher JM, Buhrlage SJ, Gray NS, Wu H.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13507-13512. doi: 10.1073/pnas.1714386114. Epub 2017 Dec 5.


Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases.

Ejaz A, Ordonez H, Jacewicz A, Ferrao R, Shuman S.

Nucleic Acids Res. 2018 Jan 9;46(1):442-455. doi: 10.1093/nar/gkx1163.


The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions.

Ferrao R, Lupardus PJ.

Front Endocrinol (Lausanne). 2017 Apr 18;8:71. doi: 10.3389/fendo.2017.00071. eCollection 2017. Review.


The Structural Basis for Class II Cytokine Receptor Recognition by JAK1.

Ferrao R, Wallweber HJ, Ho H, Tam C, Franke Y, Quinn J, Lupardus PJ.

Structure. 2016 Jun 7;24(6):897-905. doi: 10.1016/j.str.2016.03.023. Epub 2016 Apr 28.


Evaluation of genetic divergence among clones of conilon coffee after scheduled cycle pruning.

Dalcomo JM, Vieira HD, Ferreira A, Lima WL, Ferrão RG, Fonseca AF, Ferrão MA, Partelli FL.

Genet Mol Res. 2015 Nov 30;14(4):15417-26. doi: 10.4238/2015.November.30.19.


A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.

Laurent B, Ruitu L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y.

Mol Cell. 2015 Mar 19;57(6):957-970. doi: 10.1016/j.molcel.2015.01.010. Epub 2015 Feb 12.


IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly.

Ferrao R, Zhou H, Shan Y, Liu Q, Li Q, Shaw DE, Li X, Wu H.

Mol Cell. 2014 Sep 18;55(6):891-903. doi: 10.1016/j.molcel.2014.08.006. Epub 2014 Sep 4.


Elongation factor Ts directly facilitates the formation and disassembly of the Escherichia coli elongation factor Tu·GTP·aminoacyl-tRNA ternary complex.

Burnett BJ, Altman RB, Ferrao R, Alejo JL, Kaur N, Kanji J, Blanchard SC.

J Biol Chem. 2013 May 10;288(19):13917-28. doi: 10.1074/jbc.M113.460014. Epub 2013 Mar 28.


Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily.

Ferrao R, Li J, Bergamin E, Wu H.

Sci Signal. 2012 May 29;5(226):re3. doi: 10.1126/scisignal.2003124. Review.


Helical assembly in the death domain (DD) superfamily.

Ferrao R, Wu H.

Curr Opin Struct Biol. 2012 Apr;22(2):241-7. doi: 10.1016/ Epub 2012 Mar 17. Review.

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