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Items: 1 to 50 of 55

1.

Nanoelectromechanical coupling in fullerene peapods probed by resonant electrical transport experiments.

Utko P, Ferone R, Krive IV, Shekhter RI, Jonson M, Monthioux M, Noé L, Nygård J.

Nat Commun. 2010 Jul 13;1:37. doi: 10.1038/ncomms1034.

PMID:
20975710
3.

Enhanced antitumor activity for the thymidylate synthase inhibitor 1843U89 through decreased host toxicity with oral folic acid.

Smith GK, Amyx H, Boytos CM, Duch DS, Ferone R, Wilson HR.

Cancer Res. 1995 Dec 15;55(24):6117-25.

4.

Thienyl and thiazolyl acyclic analogues of 5-deazatetrahydrofolic acid.

Hodson SJ, Bigham EC, Duch DS, Smith GK, Ferone R.

J Med Chem. 1994 Jun 24;37(13):2112-5.

PMID:
8027993
5.

Benzo[f]quinazoline inhibitors of thymidylate synthase: methyleneamino-linked aroylglutamate derivatives.

Pendergast W, Dickerson SH, Dev IK, Ferone R, Duch DS, Smith GK.

J Med Chem. 1994 Mar 18;37(6):838-44.

PMID:
8145235
6.

Enzymatic synthesis of folate and antifolate polyglutamates with Escherichia coli folylpolyglutamate synthetase.

Hanlon MH, Ferone R, Weaver K, Ray P.

Anal Biochem. 1994 Feb 1;216(2):345-51.

PMID:
7513973
7.

Mode of binding of folate analogs to thymidylate synthase. Evidence for two asymmetric but interactive substrate binding sites.

Dev IK, Dallas WS, Ferone R, Hanlon M, McKee DD, Yates BB.

J Biol Chem. 1994 Jan 21;269(3):1873-82.

8.

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some sulfonamidobenzoylglutamate and related derivatives.

Pendergast W, Dickerson SH, Johnson JV, Dev IK, Ferone R, Duch DS, Smith GK.

J Med Chem. 1993 Oct 29;36(22):3464-71.

PMID:
8230138
9.

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some 3-amino- and 3-methylbenzo[f]quinazolin-1(2H)-ones.

Pendergast W, Johnson JV, Dickerson SH, Dev IK, Duch DS, Ferone R, Hall WR, Humphreys J, Kelly JM, Wilson DC.

J Med Chem. 1993 Aug 6;36(16):2279-91.

PMID:
8360872
10.

Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle.

White G, Daluge SM, Sigel CW, Ferone R, Wilson HR.

Res Vet Sci. 1993 May;54(3):372-8.

PMID:
8337486
11.

Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.

Duch DS, Banks S, Dev IK, Dickerson SH, Ferone R, Heath LS, Humphreys J, Knick V, Pendergast W, Singer S, et al.

Cancer Res. 1993 Feb 15;53(4):810-8.

12.

Synthesis and biological evaluation of N alpha-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-ornithine.

Singh SK, Singer SC, Ferone R, Waters KA, Mullin RJ, Hynes JB.

J Med Chem. 1992 May 29;35(11):2002-6.

PMID:
1375963
13.

Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents.

Bigham EC, Hodson SJ, Mallory WR, Wilson D, Duch DS, Smith GK, Ferone R.

J Med Chem. 1992 Apr 17;35(8):1399-410.

PMID:
1573633
14.

In vivo antitumor activity and metabolism of a series of 5-deazaacyclotetrahydrofolate (5-DACTHF) analogues.

Mullin RJ, Keith BR, Bigham EC, Duch DS, Ferone R, Heath LS, Singer S, Waters KA, Wilson HR.

Biochem Pharmacol. 1992 Apr 1;43(7):1627-34.

PMID:
1567484
15.

A radiometric method for objectively screening large numbers of compounds against Pneumocystis carinii in vitro.

Comley JC, Mullin RJ, Wolfe LA, Hanlon MH, Ferone R.

J Protozool. 1991 Nov-Dec;38(6):144S-146S.

PMID:
1818144
17.

Microculture screening assay for primary in vitro evaluation of drugs against Pneumocystis carinii.

Comley JC, Mullin RJ, Wolfe LA, Hanlon MH, Ferone R.

Antimicrob Agents Chemother. 1991 Oct;35(10):1965-74.

18.

Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid.

Li SW, Nair MG, Edwards DM, Kisliuk RL, Gaumont Y, Dev IK, Duch DS, Humphreys J, Smith GK, Ferone R.

J Med Chem. 1991 Sep;34(9):2746-54.

PMID:
1895294
19.

Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues.

Singh SK, Dev IK, Duch DS, Ferone R, Smith GK, Freisheim JH, Hynes JB.

J Med Chem. 1991 Feb;34(2):606-10.

PMID:
1995883
20.

In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue.

Hanlon MH, Ferone R, Mullin RJ, Keith BR.

Cancer Res. 1990 Jun 1;50(11):3207-11.

21.

Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.

Kelley JL, McLean EW, Cohn NK, Edelstein MP, Duch DS, Smith GK, Hanlon MH, Ferone R.

J Med Chem. 1990 Feb;33(2):561-7. Erratum in: J Med Chem 1990 Nov;33(11):3116.

PMID:
2299624
22.

2,4-Diamino-5-benzylpyrimidines as antibacterial agents. 13. Some alkenyl derivatives with high in vitro activity against anaerobic organisms.

Roth B, Tidwell MY, Ferone R, Baccanari DP, Sigel CW, DeAngelis D, Elwell LP.

J Med Chem. 1989 Aug;32(8):1949-58.

PMID:
2754716
23.

Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.

Patil SD, Jones C, Nair MG, Galivan J, Maley F, Kisliuk RL, Gaumont Y, Duch D, Ferone R.

J Med Chem. 1989 Jun;32(6):1284-9.

PMID:
2542557
24.

Folate analogues. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferase.

Nair MG, Murthy BR, Patil SD, Kisliuk RL, Thorndike J, Gaumont Y, Ferone R, Duch DS, Edelstein MP.

J Med Chem. 1989 Jun;32(6):1277-83.

PMID:
2498518
25.

Clinical experience with leucovorin and 5-fluorouracil.

Laufman LR, Brenckman WD Jr, Stydnicki KA, Morgan ED, Collier M, Knick VB, Duch DS, Mullin R, Ferone R.

Cancer. 1989 Mar 15;63(6 Suppl):1031-5.

PMID:
2783880
26.

Cloning, purification, and properties of Candida albicans thymidylate synthase.

Singer SC, Richards CA, Ferone R, Benedict D, Ray P.

J Bacteriol. 1989 Mar;171(3):1372-8.

27.

Clinical experience with CF-FUra.

Laufman LR, Brenckman WD Jr, Stydnicki KA, Morgan ED, Collier M, Knick VB, Duch DS, Mullin R, Ferone R.

Adv Exp Med Biol. 1988;244:201-11.

PMID:
3073655
28.

Folate analogues. 30. Synthesis and biological evaluation of N10-propargyl-5,8-dideaza-5,6,7,8-tetrahydrofolic acid and related compounds.

Nair MG, Dhawan R, Ghazala M, Kalman TI, Ferone R, Gaumont Y, Kisliuk RL.

J Med Chem. 1987 Jul;30(7):1256-61.

PMID:
3599032
29.

Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U).

Elwell LP, Ferone R, Freeman GA, Fyfe JA, Hill JA, Ray PH, Richards CA, Singer SC, Knick VB, Rideout JL, et al.

Antimicrob Agents Chemother. 1987 Feb;31(2):274-80.

30.
31.
32.

alpha-Carboxyl-linked glutamates in the folylpolyglutamates of Escherichia coli.

Ferone R, Hanlon MH, Singer SC, Hunt DF.

J Biol Chem. 1986 Dec 15;261(35):16356-62.

34.

Monocyclic pteridine analogues. Inhibition of Escherichia coli dihydropteroate synthase by 6-amino-5-nitrosoisocytosines.

Lever OW Jr, Bell LN, McGuire HM, Ferone R.

J Med Chem. 1985 Dec;28(12):1870-4.

PMID:
3906132
35.

Isolation of a dihydrofolate reductase-deficient mutant of Escherichia coli.

Singer S, Ferone R, Walton L, Elwell L.

J Bacteriol. 1985 Oct;164(1):470-2.

37.

Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

Kuyper LF, Roth B, Baccanari DP, Ferone R, Beddell CR, Champness JN, Stammers DK, Dann JG, Norrington FE, Baker DJ, et al.

J Med Chem. 1985 Mar;28(3):303-11.

PMID:
3973902
38.

Folic acid does not inactivate xanthine oxidase.

Spector T, Ferone R.

J Biol Chem. 1984 Sep 10;259(17):10784-6.

39.
40.

Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

Kuyper LF, Roth B, Baccanari DP, Ferone R, Beddell CR, Champness JN, Stammers DK, Dann JG, Norrington FE, Baker DJ, Goodford PJ.

J Med Chem. 1982 Oct;25(10):1120-2. No abstract available.

PMID:
6754932
41.

2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. 5. 3',5'-Dimethoxy-4'-substituted-benzyl analogues of trimethoprim.

Roth B, Aig E, Rauckman BS, Strelitz JZ, Phillips AP, Ferone R, Bushby SR, Sigel CW.

J Med Chem. 1981 Aug;24(8):933-41.

PMID:
7035668
42.
43.

The characteristics and significance of sulfonamides as substrates for Escherichia coli dihydropteroate synthase.

Roland S, Ferone R, Harvey RJ, Styles VL, Morrison RW.

J Biol Chem. 1979 Oct 25;254(20):10337-45. No abstract available.

44.

Folate metabolism in malaria.

Ferone R.

Bull World Health Organ. 1977;55(2-3):291-8. Review.

45.
47.

The enzymic synthesis of dihydropteroate and dihydrofolate by Plasmodium berghei.

Ferone R.

J Protozool. 1973 Aug;20(3):459-64. No abstract available.

PMID:
4354403
48.

Methotrexate therapy for P vivax malaria.

Ferone R.

JAMA. 1971 Jan 4;215(1):117. No abstract available.

PMID:
4924742
49.

Altered dihydrofolate reductase associated with drug-resistance transfer between rodent plasmodia.

Ferone R, O'Shea M, Yoeli M.

Science. 1970 Feb 27;167(3922):1263-4.

PMID:
5460847
50.

Dihydrofolate reductase from pyrimethamine-resistant Plasmodium berghei.

Ferone R.

J Biol Chem. 1970 Feb 25;245(4):850-4. No abstract available.

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