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Items: 1 to 50 of 61

1.

Lack of the aryl hydrocarbon receptor accelerates aging in mice.

Bravo-Ferrer I, Cuartero MI, Medina V, Ahedo-Quero D, Peña-Martínez C, Pérez-Ruíz A, Fernández-Valle ME, Hernández-Sánchez C, Fernández-Salguero PM, Lizasoain I, Moro MA.

FASEB J. 2019 Nov;33(11):12644-12654. doi: 10.1096/fj.201901333R. Epub 2019 Sep 4.

PMID:
31483997
2.

Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/β-Catenin Signaling.

Moreno-Marín N, Merino JM, Alvarez-Barrientos A, Patel DP, Takahashi S, González-Sancho JM, Gandolfo P, Rios RM, Muñoz A, Gonzalez FJ, Fernández-Salguero PM.

iScience. 2018 Jun 29;4:44-63. doi: 10.1016/j.isci.2018.05.006. Epub 2018 May 15.

3.

Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms.

Lorenzo-Martín LF, Citterio C, Menacho-Márquez M, Conde J, Larive RM, Rodríguez-Fdez S, García-Escudero R, Robles-Valero J, Cuadrado M, Fernández-Pisonero I, Dosil M, Sevilla MA, Montero MJ, Fernández-Salguero PM, Paramio JM, Bustelo XR.

Oncogene. 2019 Jan;38(2):209-227. doi: 10.1038/s41388-018-0433-7. Epub 2018 Aug 7.

4.

Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish.

Román AC, Vicente-Page J, Pérez-Escudero A, Carvajal-González JM, Fernández-Salguero PM, de Polavieja GG.

Genome Biol. 2018 Apr 25;19(1):55. doi: 10.1186/s13059-018-1428-y.

5.

Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism.

Miret-Casals L, Sebastián D, Brea J, Rico-Leo EM, Palacín M, Fernández-Salguero PM, Loza MI, Albericio F, Zorzano A.

Cell Chem Biol. 2018 Mar 15;25(3):268-278.e4. doi: 10.1016/j.chembiol.2017.12.001. Epub 2017 Dec 28.

6.

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value.

Roman ÁC, Carvajal-Gonzalez JM, Merino JM, Mulero-Navarro S, Fernández-Salguero PM.

Pharmacol Ther. 2018 May;185:50-63. doi: 10.1016/j.pharmthera.2017.12.003. Epub 2017 Dec 16. Review.

PMID:
29258844
7.

Lung regeneration after toxic injury is improved in absence of dioxin receptor.

Morales-Hernández A, Nacarino-Palma A, Moreno-Marín N, Barrasa E, Paniagua-Quiñones B, Catalina-Fernández I, Alvarez-Barrientos A, Bustelo XR, Merino JM, Fernández-Salguero PM.

Stem Cell Res. 2017 Dec;25:61-71. doi: 10.1016/j.scr.2017.10.009. Epub 2017 Oct 12.

8.

Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis.

Moreno-Marín N, Barrasa E, Morales-Hernández A, Paniagua B, Blanco-Fernández G, Merino JM, Fernández-Salguero PM.

Sci Rep. 2017 Sep 5;7(1):10420. doi: 10.1038/s41598-017-10984-w.

9.

piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice.

Rico-Leo EM, Moreno-Marín N, González-Rico FJ, Barrasa E, Ortega-Ferrusola C, Martín-Muñoz P, Sánchez-Guardado LO, Llano E, Alvarez-Barrientos A, Infante-Campos A, Catalina-Fernández I, Hidalgo-Sánchez M, de Rooij DG, Pendás AM, Peña FJ, Merino JM, Fernández-Salguero PM.

Open Biol. 2016 Dec;6(12). pii: 160186. doi: 10.1098/rsob.160186.

10.

Erratum: CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis.

Cibrian D, Saiz ML, de la Fuente H, Sánchez-Díaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vázquez J, Punzón C, Fresno M, Vicente-Manzanares M, Daudén E, Fernández-Salguero PM, Martín P, Sánchez-Madrid F.

Nat Immunol. 2016 Sep 20;17(10):1235. doi: 10.1038/ni1016-1235c. No abstract available.

PMID:
27648548
11.

CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis.

Cibrian D, Saiz ML, de la Fuente H, Sánchez-Díaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vázquez J, Punzón C, Fresno M, Vicente-Manzanares M, Daudén E, Fernández-Salguero PM, Martín P, Sánchez-Madrid F.

Nat Immunol. 2016 Aug;17(8):985-96. doi: 10.1038/ni.3504. Epub 2016 Jul 4. Erratum in: Nat Immunol. 2016 Sep 20;17 (10 ):1235.

12.

New Trends in Aryl Hydrocarbon Receptor Biology.

Mulero-Navarro S, Fernandez-Salguero PM.

Front Cell Dev Biol. 2016 May 11;4:45. doi: 10.3389/fcell.2016.00045. eCollection 2016. Review.

13.

RNA-Seq Analysis to Measure the Expression of SINE Retroelements.

Román ÁC, Morales-Hernández A, Fernández-Salguero PM.

Methods Mol Biol. 2016;1400:107-16. doi: 10.1007/978-1-4939-3372-3_7.

PMID:
26895049
14.

Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor.

Morales-Hernández A, González-Rico FJ, Román AC, Rico-Leo E, Alvarez-Barrientos A, Sánchez L, Macia Á, Heras SR, García-Pérez JL, Merino JM, Fernández-Salguero PM.

Nucleic Acids Res. 2016 Jun 2;44(10):4665-83. doi: 10.1093/nar/gkw095. Epub 2016 Feb 15.

15.

Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis.

Contador-Troca M, Alvarez-Barrientos A, Merino JM, Morales-Hernández A, Rodríguez MI, Rey-Barroso J, Barrasa E, Cerezo-Guisado MI, Catalina-Fernández I, Sáenz-Santamaría J, Oliver FJ, Fernandez-Salguero PM.

Mol Cancer. 2015 Aug 5;14:148. doi: 10.1186/s12943-015-0419-9.

16.

Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.

Elentner A, Ortner D, Clausen B, Gonzalez FJ, Fernández-Salguero PM, Schmuth M, Dubrac S.

Exp Dermatol. 2015 Nov;24(11):835-40. doi: 10.1111/exd.12766. Epub 2015 Jul 14.

17.

The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: role of cholesterol.

Rey-Barroso J, Alvarez-Barrientos A, Rico-Leo E, Contador-Troca M, Carvajal-Gonzalez JM, Echarri A, Del Pozo MA, Fernandez-Salguero PM.

Cell Commun Signal. 2014 Sep 21;12:57. doi: 10.1186/s12964-014-0057-7.

18.

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.

Contador-Troca M, Alvarez-Barrientos A, Barrasa E, Rico-Leo EM, Catalina-Fernández I, Menacho-Márquez M, Bustelo XR, García-Borrón JC, Gómez-Durán A, Sáenz-Santamaría J, Fernández-Salguero PM.

Carcinogenesis. 2013 Dec;34(12):2683-93. doi: 10.1093/carcin/bgt248. Epub 2013 Jul 10.

19.

Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells.

Aguilera-Montilla N, Chamorro S, Nieto C, Sánchez-Cabo F, Dopazo A, Fernández-Salguero PM, Rodríguez-Fernández JL, Pello OM, Andrés V, Cuenda A, Alonso B, Domínguez-Soto A, Sánchez-Ramón S, Corbí AL.

Blood. 2013 Apr 11;121(15):e108-17. doi: 10.1182/blood-2012-07-445106. Epub 2013 Feb 21.

PMID:
23430108
20.

Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition.

Rico-Leo EM, Alvarez-Barrientos A, Fernandez-Salguero PM.

J Biol Chem. 2013 Mar 15;288(11):7841-56. doi: 10.1074/jbc.M112.425009. Epub 2013 Feb 4.

21.

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway.

Rey-Barroso J, Colo GP, Alvarez-Barrientos A, Redondo-Muñoz J, Carvajal-González JM, Mulero-Navarro S, García-Pardo A, Teixidó J, Fernandez-Salguero PM.

Cell Signal. 2013 Apr;25(4):848-59. doi: 10.1016/j.cellsig.2013.01.010. Epub 2013 Jan 16.

PMID:
23333462
22.

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.

Portal-Nuñez S, Shankavaram UT, Rao M, Datrice N, Atay S, Aparicio M, Camphausen KA, Fernández-Salguero PM, Chang H, Lin P, Schrump DS, Garantziotis S, Cuttitta F, Zudaire E.

Cancer Res. 2012 Nov 15;72(22):5790-800. doi: 10.1158/0008-5472.CAN-12-0818. Epub 2012 Sep 19.

23.

B1-SINE retrotransposons: Establishing genomic insulatory networks.

Román AC, González-Rico FJ, Fernández-Salguero PM.

Mob Genet Elements. 2011 May;1(1):66-70.

24.

Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse.

Sánchez-Martín FJ, Fernández-Salguero PM, Merino JM.

J Neurochem. 2011 Jul;118(1):153-62. doi: 10.1111/j.1471-4159.2011.07291.x. Epub 2011 May 19.

25.

Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch.

Román AC, González-Rico FJ, Moltó E, Hernando H, Neto A, Vicente-Garcia C, Ballestar E, Gómez-Skarmeta JL, Vavrova-Anderson J, White RJ, Montoliu L, Fernández-Salguero PM.

Genome Res. 2011 Mar;21(3):422-32. doi: 10.1101/gr.111203.110. Epub 2011 Feb 3.

26.

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells.

Sánchez-Martín FJ, Fernández-Salguero PM, Merino JM.

Neurotoxicology. 2010 Jun;31(3):267-76. doi: 10.1016/j.neuro.2010.03.005. Epub 2010 Mar 17.

PMID:
20302886
27.
28.

Role of transforming growth factor beta in cancer microenvironment.

de la Cruz-Merino L, Henao-Carrasco F, García-Manrique T, Fernández-Salguero PM, Codes-Manuel de Villena M.

Clin Transl Oncol. 2009 Nov;11(11):715-20. Review.

PMID:
19917534
29.

Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma.

Roman AC, Carvajal-Gonzalez JM, Rico-Leo EM, Fernandez-Salguero PM.

J Biol Chem. 2009 Sep 11;284(37):25135-48. doi: 10.1074/jbc.M109.013292. Epub 2009 Jul 18.

30.

Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta.

Carvajal-Gonzalez JM, Roman AC, Cerezo-Guisado MI, Rico-Leo EM, Martin-Partido G, Fernandez-Salguero PM.

J Cell Sci. 2009 Jun 1;122(Pt 11):1823-33. doi: 10.1242/jcs.047274. Epub 2009 May 12.

31.

Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells.

Benitez DA, Hermoso MA, Pozo-Guisado E, Fernández-Salguero PM, Castellón EA.

Prostate. 2009 Jul 1;69(10):1045-54. doi: 10.1002/pros.20953.

PMID:
19301309
32.

The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.

Carvajal-Gonzalez JM, Mulero-Navarro S, Roman AC, Sauzeau V, Merino JM, Bustelo XR, Fernandez-Salguero PM.

Mol Biol Cell. 2009 Mar;20(6):1715-27. doi: 10.1091/mbc.E08-05-0451. Epub 2009 Jan 21.

33.

Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling.

Gomez-Duran A, Carvajal-Gonzalez JM, Mulero-Navarro S, Santiago-Josefat B, Puga A, Fernandez-Salguero PM.

Biochem Pharmacol. 2009 Feb 15;77(4):700-12. doi: 10.1016/j.bcp.2008.08.032. Epub 2008 Sep 5. Review.

PMID:
18812170
34.

Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner.

Gomez-Duran A, Ballestar E, Carvajal-Gonzalez JM, Marlowe JL, Puga A, Esteller M, Fernandez-Salguero PM.

J Mol Biol. 2008 Jun 27;380(1):1-16. doi: 10.1016/j.jmb.2008.04.056. Epub 2008 Apr 30.

35.

Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo.

Roman AC, Benitez DA, Carvajal-Gonzalez JM, Fernandez-Salguero PM.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1632-7. doi: 10.1073/pnas.0708366105. Epub 2008 Jan 25.

36.

Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway.

Benitez DA, Pozo-Guisado E, Clementi M, Castellón E, Fernandez-Salguero PM.

Br J Cancer. 2007 May 21;96(10):1595-604. Epub 2007 May 8.

37.

The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

Barouki R, Coumoul X, Fernandez-Salguero PM.

FEBS Lett. 2007 Jul 31;581(19):3608-15. Epub 2007 Mar 30. Review.

38.

Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines.

Benitez DA, Pozo-Guisado E, Alvarez-Barrientos A, Fernandez-Salguero PM, Castellón EA.

J Androl. 2007 Mar-Apr;28(2):282-93. Epub 2006 Oct 18.

39.

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

Mulero-Navarro S, Carvajal-Gonzalez JM, Herranz M, Ballestar E, Fraga MF, Ropero S, Esteller M, Fernandez-Salguero PM.

Carcinogenesis. 2006 May;27(5):1099-104. Epub 2006 Jan 12.

PMID:
16410262
40.

Improving cancer therapeutics by molecular profiling.

Corchero J, Fernández-Salguero PM.

Curr Drug Metab. 2005 Dec;6(6):553-68. Review.

PMID:
16379669
41.

LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity: Role of extracellular proteases plasmin and elastase.

Gomez-Duran A, Mulero-Navarro S, Chang X, Fernandez-Salguero PM.

J Cell Biochem. 2006 Feb 1;97(2):380-92.

PMID:
16187295
42.

Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model.

Mulero-Navarro S, Pozo-Guisado E, Pérez-Mancera PA, Alvarez-Barrientos A, Catalina-Fernández I, Hernández-Nieto E, Sáenz-Santamaria J, Martínez N, Rojas JM, Sánchez-García I, Fernández-Salguero PM.

J Biol Chem. 2005 Aug 5;280(31):28731-41. Epub 2005 Jun 9.

43.

Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB.

Pozo-Guisado E, Merino JM, Mulero-Navarro S, Lorenzo-Benayas MJ, Centeno F, Alvarez-Barrientos A, Fernandez-Salguero PM.

Int J Cancer. 2005 May 20;115(1):74-84. Erratum in: Int J Cancer. 2005 Oct 10;116(6):1004. Salguero, Pedro M Fernandez [corrected to Fernandez-Salguero, Pedro M].

44.

Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-beta-binding protein-1.

Corchero J, Martín-Partido G, Dallas SL, Fernández-Salguero PM.

Int J Exp Pathol. 2004 Oct;85(5):295-302.

45.

Overexpression of latent transforming growth factor-beta binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts.

Santiago-Josefat B, Mulero-Navarro S, Dallas SL, Fernandez-Salguero PM.

J Cell Sci. 2004 Feb 29;117(Pt 6):849-59. Epub 2004 Feb 3.

46.
47.

Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: role of nitric oxide accumulation.

Mulero-Navarro S, Santiago-Josefat B, Pozo-Guisado E, Merino JM, Fernandez-Salguero PM.

Eur J Neurosci. 2003 Oct;18(8):2265-72.

PMID:
14622187
48.
49.

Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons.

Valera E, Fernández-Salguero PM, Planells-Cases R, Messeguer A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Merino JM.

Neuromolecular Med. 2002;2(3):271-80.

PMID:
12622405
50.

The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle.

Pozo-Guisado E, Alvarez-Barrientos A, Mulero-Navarro S, Santiago-Josefat B, Fernandez-Salguero PM.

Biochem Pharmacol. 2002 Nov 1;64(9):1375-86.

PMID:
12392819

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