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Items: 1 to 50 of 98

1.

Electromagnetic behavior of dielectric objects on metallic periodically nanostructured substrates.

Barreda ÁI, Otaduy D, Martín-Rodríguez R, Merino S, Fernández-Luna JL, González F, Moreno F.

Opt Express. 2018 Apr 30;26(9):11222-11237. doi: 10.1364/OE.26.011222.

PMID:
29716047
2.

NFκB activation in differentiating glioblastoma stem-like cells is promoted by hyaluronic acid signaling through TLR4.

Ferrandez E, Gutierrez O, Segundo DS, Fernandez-Luna JL.

Sci Rep. 2018 Apr 20;8(1):6341. doi: 10.1038/s41598-018-24444-6.

3.

Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.

Torices S, Alvarez-Rodríguez L, Varela I, Muñoz P, Balsa A, López-Hoyos M, Martinez-Taboada V, Fernández-Luna JL.

Immunol Lett. 2017 Jul;187:35-40. doi: 10.1016/j.imlet.2017.04.011. Epub 2017 May 7.

PMID:
28495399
4.

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis.

Torices S, Julia A, Muñoz P, Varela I, Balsa A, Marsal S, Fernández-Nebro A, Blanco F, López-Hoyos M, Martinez-Taboada V, Fernández-Luna JL.

Arthritis Res Ther. 2016 Oct 4;18(1):221.

5.

ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.

Talamillo A, Grande L, Ruiz-Ontañon P, Velasquez C, Mollinedo P, Torices S, Sanchez-Gomez P, Aznar A, Esparis-Ogando A, Lopez-Lopez C, Lafita C, Berciano MT, Montero JA, Vazquez-Barquero A, Segura V, Villagra NT, Pandiella A, Lafarga M, Leon J, Martinez-Climent JA, Sanz-Moreno V, Fernandez-Luna JL.

Oncogene. 2017 Mar 23;36(12):1733-1744. doi: 10.1038/onc.2016.341. Epub 2016 Sep 19.

PMID:
27641332
6.

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.

Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA.

Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889.

7.

A Truncated Variant of ASCC1, a Novel Inhibitor of NF-κB, Is Associated with Disease Severity in Patients with Rheumatoid Arthritis.

Torices S, Alvarez-Rodríguez L, Grande L, Varela I, Muñoz P, Pascual D, Balsa A, López-Hoyos M, Martinez-Taboada V, Fernández-Luna JL.

J Immunol. 2015 Dec 1;195(11):5415-20. doi: 10.4049/jimmunol.1501532. Epub 2015 Oct 26.

8.

Inhibition of Cancer Cell Migration by Multiwalled Carbon Nanotubes.

García-Hevia L, Valiente R, Fernández-Luna JL, Flahaut E, Rodríguez-Fernández L, Villegas JC, González J, Fanarraga ML.

Adv Healthc Mater. 2015 Aug 5;4(11):1640-4. doi: 10.1002/adhm.201500252. Epub 2015 Jun 11.

PMID:
26097131
9.

Anti-cancer cytotoxic effects of multiwalled carbon nanotubes.

Garcia-Hevia L, Valiente R, Gonzalez J, Fernandez-Luna JL, Villegas JC, Fanarraga ML.

Curr Pharm Des. 2015;21(15):1920-9. Review.

PMID:
25732667
10.

Culture dimensionality influences the resistance of glioblastoma stem-like cells to multikinase inhibitors.

Fernandez-Fuente G, Mollinedo P, Grande L, Vazquez-Barquero A, Fernandez-Luna JL.

Mol Cancer Ther. 2014 Jun;13(6):1664-72. doi: 10.1158/1535-7163.MCT-13-0854. Epub 2014 Apr 10.

11.

Copy number variations in endoglin locus: mapping of large deletions in Spanish families with hereditary hemorrhagic telangiectasia type 1.

Fontalba A, Fernández-Luna JL, Zarrabeitia R, Recio-Poveda L, Albiñana V, Ojeda-Fernández ML, Bernabéu C, Alcaraz LA, Botella LM.

BMC Med Genet. 2013 Nov 25;14:121. doi: 10.1186/1471-2350-14-121.

12.

Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells.

Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, Aznar MA, Díez-Valle R, Tejada-Solís S, Alonso MM, Fernandez-Luna JL, Martinez-Climent JA, Malumbres R.

PLoS One. 2013 Oct 14;8(10):e77098. doi: 10.1371/journal.pone.0077098. eCollection 2013.

13.

Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue.

Ruiz-Ontañon P, Orgaz JL, Aldaz B, Elosegui-Artola A, Martino J, Berciano MT, Montero JA, Grande L, Nogueira L, Diaz-Moralli S, Esparís-Ogando A, Vazquez-Barquero A, Lafarga M, Pandiella A, Cascante M, Segura V, Martinez-Climent JA, Sanz-Moreno V, Fernandez-Luna JL.

Stem Cells. 2013 Jun;31(6):1075-85. doi: 10.1002/stem.1349.

14.

Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.

Grande L, Bretones G, Rosa-Garrido M, Garrido-Martin EM, Hernandez T, Fraile S, Botella L, de Alava E, Vidal A, Garcia del Muro X, Villanueva A, Delgado MD, Fernandez-Luna JL.

J Biol Chem. 2012 Aug 3;287(32):26495-505. doi: 10.1074/jbc.M112.376319. Epub 2012 Jun 20.

15.

The NFκB pathway: a therapeutic target in glioblastoma.

Nogueira L, Ruiz-Ontañon P, Vazquez-Barquero A, Moris F, Fernandez-Luna JL.

Oncotarget. 2011 Aug;2(8):646-53. Review.

16.

Expression and function of toll-like receptors in peripheral blood mononuclear cells of patients with polymyalgia rheumatica and giant cell arteritis.

Álvarez Rodríguez L, López-Hoyos M, Mata C, Fontalba A, Calvo Alen J, Marín MJ, Fernández-Luna JL, Aguero Balbín J, Aranzamendi Zaldunbide M, Blanco R, Martínez-Taboada VM.

Ann Rheum Dis. 2011 Sep;70(9):1677-83. doi: 10.1136/ard.2010.140194. Epub 2011 Jun 13.

PMID:
21670089
17.

Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.

Nogueira L, Ruiz-Ontañon P, Vazquez-Barquero A, Lafarga M, Berciano MT, Aldaz B, Grande L, Casafont I, Segura V, Robles EF, Suarez D, Garcia LF, Martinez-Climent JA, Fernandez-Luna JL.

Oncogene. 2011 Aug 11;30(32):3537-48. doi: 10.1038/onc.2011.74. Epub 2011 Mar 21.

PMID:
21423202
18.

A novel pathway of TEF regulation mediated by microRNA-125b contributes to the control of actin distribution and cell shape in fibroblasts.

Gutierrez O, Berciano MT, Lafarga M, Fernandez-Luna JL.

PLoS One. 2011 Feb 11;6(2):e17169. doi: 10.1371/journal.pone.0017169.

19.

[Prevalence of the A1555G MTDNA mutation in sporadic hearing-impaired patients without known history of aminoglycoside treatment].

Morales Angulo C, Gallo-Terán J, Señaris B, Fontalva A, González-Aguado R, Fernández-Luna JL.

Acta Otorrinolaringol Esp. 2011 Mar-Apr;62(2):83-6. doi: 10.1016/j.otorri.2010.08.003. Epub 2010 Dec 3. Spanish.

20.

Elevated levels of IL-1beta in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferation.

Ibáñez A, Río P, Casado JA, Bueren JA, Fernández-Luna JL, Pipaón C.

Biochem J. 2009 Jul 29;422(1):161-70. doi: 10.1042/BJ20082118.

PMID:
19473116
21.

Association of the aromatase gene alleles with BMD: epidemiological and functional evidence.

Riancho JA, Sañudo C, Valero C, Pipaón C, Olmos JM, Mijares V, Fernández-Luna JL, Zarrabeitia MT.

J Bone Miner Res. 2009 Oct;24(10):1709-18. doi: 10.1359/jbmr.090404.

22.

Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk.

Fontalba A, Gutiérrez O, Llorca J, Mateo I, Vázquez-Higuera JL, Berciano J, Fernández-Luna JL, Combarros O.

J Neurol. 2009 Jul;256(7):1184-6. doi: 10.1007/s00415-009-5080-z. Epub 2009 Mar 1. No abstract available.

PMID:
19252766
23.

PAR bZIP-bik is a novel transcriptional pathway that mediates oxidative stress-induced apoptosis in fibroblasts.

Ritchie A, Gutierrez O, Fernandez-Luna JL.

Cell Death Differ. 2009 Jun;16(6):838-46. doi: 10.1038/cdd.2009.13. Epub 2009 Feb 13.

24.

Deficiency of CARD8 is associated with increased Alzheimer's disease risk in women.

Fontalba A, Gutiérrez O, Llorca J, Mateo I, Berciano J, Fernández-Luna JL, Combarros O.

Dement Geriatr Cogn Disord. 2008;26(3):247-50. doi: 10.1159/000160956. Epub 2008 Oct 8.

PMID:
18841008
25.

Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia.

Fontalba A, Fernandez-L A, García-Alegria E, Albiñana V, Garrido-Martin EM, Blanco FJ, Zarrabeitia R, Perez-Molino A, Bernabeu-Herrero ME, Ojeda ML, Fernandez-Luna JL, Bernabeu C, Botella LM.

BMC Med Genet. 2008 Aug 1;9:75. doi: 10.1186/1471-2350-9-75.

26.

Regulation of pro-apoptotic BH3-only proteins and its contribution to cancer progression and chemoresistance.

Fernandez-Luna JL.

Cell Signal. 2008 Nov;20(11):1921-6. doi: 10.1016/j.cellsig.2008.04.015. Epub 2008 May 8. Review.

PMID:
18555662
27.

Plexin B1 is downregulated in renal cell carcinomas and modulates cell growth.

Gómez Román JJ, Garay GO, Saenz P, Escuredo K, Sanz Ibayondo C, Gutkind S, Junquera C, Simón L, Martínez A, Fernández Luna JL, Val-Bernal JF.

Transl Res. 2008 Mar;151(3):134-40. doi: 10.1016/j.trsl.2007.12.003. Epub 2008 Jan 7.

PMID:
18279812
28.
29.

Apoptosis regulators as targets for cancer therapy.

Fernández-Luna JL.

Clin Transl Oncol. 2007 Sep;9(9):555-62. Review.

PMID:
17921102
30.

Deficiency of the NF-kappaB inhibitor caspase activating and recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity.

Fontalba A, Martinez-Taboada V, Gutierrez O, Pipaon C, Benito N, Balsa A, Blanco R, Fernandez-Luna JL.

J Immunol. 2007 Oct 1;179(7):4867-73.

31.

Cannabinoid receptors as novel targets for the treatment of melanoma.

Blázquez C, Carracedo A, Barrado L, Real PJ, Fernández-Luna JL, Velasco G, Malumbres M, Guzmán M.

FASEB J. 2006 Dec;20(14):2633-5. Epub 2006 Oct 25.

PMID:
17065222
32.

A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene.

Benito A, Gutierrez O, Pipaon C, Real PJ, Gachon F, Ritchie AE, Fernandez-Luna JL.

J Biol Chem. 2006 Dec 15;281(50):38351-7. Epub 2006 Oct 20.

33.

Transcriptional activation of the proapoptotic bik gene by E2F proteins in cancer cells.

Real PJ, Sanz C, Gutierrez O, Pipaon C, Zubiaga AM, Fernandez-Luna JL.

FEBS Lett. 2006 Oct 30;580(25):5905-9. Epub 2006 Oct 2.

34.

A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.

Rodriguez-Sanjuan JC, Fontalba A, Mayorga M, Bordin MC, Hyland SJ, Trugeda S, Garcia RA, Gomez-Fleitas M, Fernandez F, Caldas C, Fernandez-Luna JL.

Eur J Surg Oncol. 2006 Dec;32(10):1110-3. Epub 2006 Jul 25.

PMID:
16870389
35.

Identification of c-Kit gene mutations in patients with polycythemia vera.

Fontalba A, Real PJ, Fernandez-Luna JL, Agirre X, Prosper F, Richard C.

Leuk Res. 2006 Oct;30(10):1325-6. Epub 2006 Feb 7.

PMID:
16460801
36.

Blockade of epidermal growth factor receptors chemosensitizes breast cancer cells through up-regulation of Bnip3L.

Real PJ, Benito A, Cuevas J, Berciano MT, de Juan A, Coffer P, Gomez-Roman J, Lafarga M, Lopez-Vega JM, Fernandez-Luna JL.

Cancer Res. 2005 Sep 15;65(18):8151-7.

38.

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

Rubio-Moscardo F, Blesa D, Mestre C, Siebert R, Balasas T, Benito A, Rosenwald A, Climent J, Martinez JI, Schilhabel M, Karran EL, Gesk S, Esteller M, deLeeuw R, Staudt LM, Fernandez-Luna JL, Pinkel D, Dyer MJ, Martinez-Climent JA.

Blood. 2005 Nov 1;106(9):3214-22. Epub 2005 Jul 28.

39.

Successful treatment of refractory Schnitzler syndrome with anakinra: comment on the article by Hawkins et al.

Martinez-Taboada VM, Fontalba A, Blanco R, Fernández-Luna JL.

Arthritis Rheum. 2005 Jul;52(7):2226-7. No abstract available.

40.

Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2.

Real PJ, Cao Y, Wang R, Nikolovska-Coleska Z, Sanz-Ortiz J, Wang S, Fernandez-Luna JL.

Cancer Res. 2004 Nov 1;64(21):7947-53.

41.

Gene-gene interaction between interleukin-6 and interleukin-10 reduces AD risk.

Infante J, Sanz C, Fernández-Luna JL, Llorca J, Berciano J, Combarros O.

Neurology. 2004 Sep 28;63(6):1135-6. No abstract available.

PMID:
15452323
42.

NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.

Sanz C, Calasanz MJ, Andreu E, Richard C, Prosper F, Fernandez-Luna JL.

Biochem J. 2004 Dec 1;384(Pt 2):281-6.

43.

Ipaf is upregulated by tumor necrosis factor-alpha in human leukemia cells.

Gutierrez O, Pipaon C, Fernandez-Luna JL.

FEBS Lett. 2004 Jun 18;568(1-3):79-82.

44.

Gene-gene interaction between interleukin-1A and interleukin-8 increases Alzheimer's disease risk.

Infante J, Sanz C, Fernández-Luna JL, Llorca J, Berciano J, Combarros O.

J Neurol. 2004 Apr;251(4):482-3. No abstract available.

PMID:
15083298
45.

A comparison of learning algorithms for Bayesian networks: a case study based on data from an emergency medical service.

Acid S, de Campos LM, Fernández-Luna JM, Rodríguez S, María Rodríguez J, Luis Salcedo J.

Artif Intell Med. 2004 Mar;30(3):215-32.

PMID:
15081073
46.

Imatinib inhibits proliferation of Ewing tumor cells mediated by the stem cell factor/KIT receptor pathway, and sensitizes cells to vincristine and doxorubicin-induced apoptosis.

González I, Andreu EJ, Panizo A, Inogés S, Fontalba A, Fernández-Luna JL, Gaboli M, Sierrasesúmaga L, Martín-Algarra S, Pardo J, Prósper F, de Alava E.

Clin Cancer Res. 2004 Jan 15;10(2):751-61.

47.

Lack of Bcr-Abl point mutations in chronic myeloid leukemia patients in chronic phase before imatinib treatment is not predictive of response.

Agirre X, Fontalba A, Andreu EJ, Odero MD, Larráyoz MJ, Montiel C, Calasanz MJ, Fernández-Luna JL, Prósper F.

Haematologica. 2003 Dec;88(12):1425-6. No abstract available.

48.

Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells.

Acosta JC, Richard C, Delgado MD, Horita M, Rizzo MG, Fernández-Luna JL, León J.

Mol Cancer Ther. 2003 Sep;2(9):893-900.

49.

Jun N-terminal kinase activity and early growth-response factor-1 gene expression are down-regulated in Fanconi anemia group A lymphoblasts.

Pipaon C, Casado JA, Bueren JA, Fernandez-Luna JL.

Blood. 2004 Jan 1;103(1):128-32. Epub 2003 Sep 4.

50.

Interaction of the H63D mutation in the hemochromatosis gene with the apolipoprotein E epsilon 4 allele modulates age at onset of Alzheimer's disease.

Combarros O, García-Román M, Fontalba A, Fernández-Luna JL, Llorca J, Infante J, Berciano J.

Dement Geriatr Cogn Disord. 2003;15(3):151-4.

PMID:
12584430

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