Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 24

1.

β-Glucan as an immune activator and a carrier in the construction of a synthetic MUC1 vaccine.

Wang H, Yang B, Wang Y, Liu F, Fernández-Tejada A, Dong S.

Chem Commun (Camb). 2018 Dec 20;55(2):253-256. doi: 10.1039/c8cc07691j.

PMID:
30534737
2.

Antibodies Against Specific MUC16 Glycosylation Sites Inhibit Ovarian Cancer Growth.

Rao TD, Fernández-Tejada A, Axelrod A, Rosales N, Yan X, Thapi S, Wang A, Park KJ, Nemieboka B, Xiang J, Lewis JS, Olvera N, Levine DA, Danishefsky SJ, Spriggs DR.

ACS Chem Biol. 2017 Aug 18;12(8):2085-2096. doi: 10.1021/acschembio.7b00305. Epub 2017 Jun 28.

3.

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Alam SM, Aussedat B, Vohra Y, Meyerhoff RR, Cale EM, Walkowicz WE, Radakovich NA, Anasti K, Armand L, Parks R, Sutherland L, Scearce R, Joyce MG, Pancera M, Druz A, Georgiev IS, Von Holle T, Eaton A, Fox C, Reed SG, Louder M, Bailer RT, Morris L, Abdool-Karim SS, Cohen M, Liao HX, Montefiori DC, Park PK, Fernández-Tejada A, Wiehe K, Santra S, Kepler TB, Saunders KO, Sodroski J, Kwong PD, Mascola JR, Bonsignori M, Moody MA, Danishefsky S, Haynes BF.

Sci Transl Med. 2017 Mar 15;9(381). pii: eaai7521. doi: 10.1126/scitranslmed.aai7521.

4.

Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21.

Fernández-Tejada A, Walkowicz WE, Tan DS, Gin DY.

Methods Mol Biol. 2017;1494:45-71.

5.

Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis.

Fernández-Tejada A, Tan DS, Gin DY.

Acc Chem Res. 2016 Sep 20;49(9):1741-56. doi: 10.1021/acs.accounts.6b00242. Epub 2016 Aug 28.

6.

Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities.

Walkowicz WE, Fernández-Tejada A, George C, Corzana F, Jiménez-Barbero J, Ragupathi G, Tan DS, Gin DY.

Chem Sci. 2016 Mar;7(3):2371-2380. Epub 2016 Jan 15.

7.

Correction: Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants.

Fernández-Tejada A, Tan DS, Gin DY.

Chem Commun (Camb). 2015 Oct 1;51(76):14410. doi: 10.1039/c5cc90397a. Epub 2015 Sep 3.

PMID:
26334089
8.

Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants.

Fernández-Tejada A, Tan DS, Gin DY.

Chem Commun (Camb). 2015 Sep 21;51(73):13949-52. doi: 10.1039/c5cc05244k. Erratum in: Chem Commun (Camb). 2015 Oct 1;51(76):14410.

9.

Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics.

Fernández-Tejada A, Cañada FJ, Jiménez-Barbero J.

Chemistry. 2015 Jul 20;21(30):10616-28. doi: 10.1002/chem.201500831. Epub 2015 Jun 10. Review.

PMID:
26095198
10.

Glycans in Medicinal Chemistry: An Underexploited Resource.

Fernández-Tejada A, Cañada FJ, Jiménez-Barbero J.

ChemMedChem. 2015 Aug;10(8):1291-5. doi: 10.1002/cmdc.201500107. Epub 2015 May 14.

PMID:
25974358
11.

Designing synthetic vaccines for HIV.

Fernández-Tejada A, Haynes BF, Danishefsky SJ.

Expert Rev Vaccines. 2015 Jun;14(6):815-31. doi: 10.1586/14760584.2015.1027690. Epub 2015 Mar 31. Review.

12.

Total synthesis of glycosylated proteins.

Fernández-Tejada A, Brailsford J, Zhang Q, Shieh JH, Moore MA, Danishefsky SJ.

Top Curr Chem. 2015;362:1-26. doi: 10.1007/128_2014_622. Review.

13.

Conformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation.

Somovilla VJ, Martinez-Sáez N, Fernández-Tejada A, de la Torre BG, Andreu D, Jimenez-Barbero J, L Asensio J, Avenoza A, Busto JH, Corzana F, Peregrina JM.

Curr Top Med Chem. 2014;14(23):2712-21.

PMID:
25515748
14.

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol.

Fernández-Tejada A, Chea EK, George C, Gardner JR, Livingston PO, Ragupathi G, Tan DS, Gin DY.

Bioorg Med Chem. 2014 Nov 1;22(21):5917-23. doi: 10.1016/j.bmc.2014.09.016. Epub 2014 Sep 17.

15.

Development of a minimal saponin vaccine adjuvant based on QS-21.

Fernández-Tejada A, Chea EK, George C, Pillarsetty N, Gardner JR, Livingston PO, Ragupathi G, Lewis JS, Tan DS, Gin DY.

Nat Chem. 2014 Jul;6(7):635-43. doi: 10.1038/nchem.1963. Epub 2014 Jun 1.

16.

Chemical synthesis of the β-subunit of human luteinizing (hLH) and chorionic gonadotropin (hCG) glycoprotein hormones.

Fernández-Tejada A, Vadola PA, Danishefsky SJ.

J Am Chem Soc. 2014 Jun 11;136(23):8450-8. doi: 10.1021/ja503545r. Epub 2014 May 27.

17.

Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors.

Alam SM, Dennison SM, Aussedat B, Vohra Y, Park PK, Fernández-Tejada A, Stewart S, Jaeger FH, Anasti K, Blinn JH, Kepler TB, Bonsignori M, Liao HX, Sodroski JG, Danishefsky SJ, Haynes BF.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18214-9. doi: 10.1073/pnas.1317855110. Epub 2013 Oct 21.

18.

Chemical synthesis of highly congested gp120 V1V2 N-glycopeptide antigens for potential HIV-1-directed vaccines.

Aussedat B, Vohra Y, Park PK, Fernández-Tejada A, Alam SM, Dennison SM, Jaeger FH, Anasti K, Stewart S, Blinn JH, Liao HX, Sodroski JG, Haynes BF, Danishefsky SJ.

J Am Chem Soc. 2013 Sep 4;135(35):13113-20. doi: 10.1021/ja405990z. Epub 2013 Aug 22.

19.

Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes.

Chea EK, Fernández-Tejada A, Damani P, Adams MM, Gardner JR, Livingston PO, Ragupathi G, Gin DY.

J Am Chem Soc. 2012 Aug 15;134(32):13448-57. doi: 10.1021/ja305121q. Epub 2012 Aug 6.

20.

Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: binding modulation by the underlying Ser or Thr amino acids.

Corzana F, Fernández-Tejada A, Busto JH, Joshi G, Davis AP, Jiménez-Barbero J, Avenoza A, Peregrina JM.

Chembiochem. 2011 Jan 3;12(1):110-7. doi: 10.1002/cbic.201000526.

PMID:
21181845
21.

Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.

Fernández-Tejada A, Corzana F, Busto JH, Avenoza A, Peregrina JM.

J Org Chem. 2009 Dec 18;74(24):9305-13. doi: 10.1021/jo901988w.

PMID:
19924838
22.

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

Fernández-Tejada A, Corzana F, Busto JH, Avenoza A, Peregrina JM.

Org Biomol Chem. 2009 Jul 21;7(14):2885-93. doi: 10.1039/b907091p. Epub 2009 Jun 8.

PMID:
19582298
23.

Insights into the geometrical features underlying beta-O-GlcNAc glycosylation: water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone.

Fernández-Tejada A, Corzana F, Busto JH, Jiménez-Osés G, Jiménez-Barbero J, Avenoza A, Peregrina JM.

Chemistry. 2009 Jul 27;15(30):7297-301. doi: 10.1002/chem.200901204. No abstract available.

PMID:
19544521
24.

Non-natural amino acids as modulating agents of the conformational space of model glycopeptides.

Fernández-Tejada A, Corzana F, Busto JH, Jiménez-Osés G, Peregrina JM, Avenoza A.

Chemistry. 2008;14(23):7042-58. doi: 10.1002/chem.200800460.

PMID:
18604849

Supplemental Content

Loading ...
Support Center