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Items: 1 to 50 of 105

1.

Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells.

Gonzalez-Sanchez L, Cobos-Fernandez MA, Lopez-Nieva P, Villa-Morales M, Stamatakis K, Cuezva JM, Marin Rubio JL, Vazquez-Dominguez I, Gonzalez-Vasconcellos I, Salido E, Llamas P, Lopez-Lorenzo JL, Santos J, Fernandez-Piqueras J.

Carcinogenesis. 2019 Nov 17. pii: bgz185. doi: 10.1093/carcin/bgz185. [Epub ahead of print]

PMID:
31734690
2.

The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data.

Fernández-Navarro P, López-Nieva P, Piñeiro-Yañez E, Carreño-Tarragona G, Martinez-López J, Sánchez Pérez R, Aroca Á, Al-Shahrour F, Cobos-Fernández MÁ, Fernández-Piqueras J.

BMC Cancer. 2019 Oct 26;19(1):1005. doi: 10.1186/s12885-019-6209-9.

3.

FADD in Cancer: Mechanisms of Altered Expression and Function, and Clinical Implications.

Marín-Rubio JL, Vela-Martín L, Fernández-Piqueras J, Villa-Morales M.

Cancers (Basel). 2019 Sep 29;11(10). pii: E1462. doi: 10.3390/cancers11101462. Review.

4.

Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma.

López-Nieva P, Fernández-Navarro P, Graña-Castro O, Andrés-León E, Santos J, Villa-Morales M, Cobos-Fernández MÁ, González-Sánchez L, Malumbres M, Salazar-Roa M, Fernández-Piqueras J.

Sci Rep. 2019 Mar 26;9(1):5179. doi: 10.1038/s41598-019-41675-3.

5.

S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma.

Marín-Rubio JL, Pérez-Gómez E, Fernández-Piqueras J, Villa-Morales M.

Carcinogenesis. 2019 Oct 16;40(10):1260-1268. doi: 10.1093/carcin/bgz041.

PMID:
30805584
6.

Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.

Vázquez-Domínguez I, González-Sánchez L, López-Nieva P, Fernández-Navarro P, Villa-Morales M, Cobos-Fernández MÁ, Sastre I, F Fraga M, F Fernández A, Malumbres M, Salazar-Roa M, Graña-Castro O, Santos J, Llamas P, López-Lorenzo JL, Fernández-Piqueras J.

Oncogene. 2019 Jun;38(23):4620-4636. doi: 10.1038/s41388-019-0746-1. Epub 2019 Feb 11.

PMID:
30742097
7.

RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.

López-Nieva P, Fernández-Navarro P, Vaquero-Lorenzo C, Villa-Morales M, Graña-Castro O, Cobos-Fernández MÁ, López-Lorenzo JL, Llamas P, González-Sanchez L, Sastre I, Pollan M, Malumbres M, Santos J, Fernández-Piqueras J.

BMC Cancer. 2018 Apr 16;18(1):430. doi: 10.1186/s12885-018-4304-y.

8.

New mutations for nodal lymphomas of TFH origin.

Fernández-Piqueras J.

Blood. 2016 Sep 15;128(11):1446-7. doi: 10.1182/blood-2016-07-726455. No abstract available.

PMID:
27633606
9.

Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated apoptosis.

López-Nieva P, Malavé M, González-Sánchez L, Fernández-Piqueras J, Fernández-Navarro P, Santos J.

BMC Genomics. 2016 Aug 31;17:698. doi: 10.1186/s12864-016-3036-0.

10.

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma.

Marín-Rubio JL, de Arriba MC, Cobos-Fernández MA, González-Sánchez L, Ors I, Sastre I, Fernández-Piqueras J, Villa-Morales M.

Oncotarget. 2016 Sep 20;7(38):61485-61499. doi: 10.18632/oncotarget.11370.

11.

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression.

Bueno MJ, Pérez de Castro I, Gómez de Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernández-Piqueras J, Malumbres M.

Cancer Cell. 2016 Apr 11;29(4):607-608. doi: 10.1016/j.ccell.2016.03.013. No abstract available.

12.

Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.

Roncero AM, López-Nieva P, Cobos-Fernández MA, Villa-Morales M, González-Sánchez L, López-Lorenzo JL, Llamas P, Ayuso C, Rodríguez-Pinilla SM, Arriba MC, Piris MA, Fernández-Navarro P, Fernández AF, Fraga MF, Santos J, Fernández-Piqueras J.

Leukemia. 2016 Jan;30(1):94-103. doi: 10.1038/leu.2015.202. Epub 2015 Jul 28.

13.

Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer.

Pérez-Gómez E, Andradas C, Blasco-Benito S, Caffarel MM, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, Stickeler E, Staebler A, Bauer M, Arnold N, Soriano J, Pérez-Martínez M, Megías D, Moreno-Bueno G, Ortega-Gutiérrez S, Artola M, Vázquez-Villa H, Quintanilla M, Fernández-Piqueras J, Canela EI, McCormick PJ, Guzmán M, Sánchez C.

J Natl Cancer Inst. 2015 Apr 8;107(6):djv077. doi: 10.1093/jnci/djv077. Print 2015 Jun.

14.

Putative association between the -1415 T/C polymorphism of spermidine/spermine N1-acetyltransferase (SSAT1) gene and alcohol use disorders in women and men.

Vaquero-Lorenzo C, López-Castromán J, Bermudo-Soriano CR, Saiz-Ruiz J, Fernández-Piqueras J, Baca-García E.

Am J Drug Alcohol Abuse. 2014 May;40(3):240-3. doi: 10.3109/00952990.2014.891039. Epub 2014 Apr 15.

PMID:
24735382
15.

FAS system deregulation in T-cell lymphoblastic lymphoma.

Villa-Morales M, Cobos MA, González-Gugel E, Álvarez-Iglesias V, Martínez B, Piris MA, Carracedo A, Benítez J, Fernández-Piqueras J.

Cell Death Dis. 2014 Mar 6;5:e1110. doi: 10.1038/cddis.2014.83.

16.

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment.

Almoguera B, Riveiro-Alvarez R, Lopez-Castroman J, Dorado P, Vaquero-Lorenzo C, Fernandez-Piqueras J, Llerena A, Abad-Santos F, Baca-García E, Dal-Ré R, Ayuso C; Spanish Consortium of Pharmacogenetics Research in Schizophrenia.

Pharmacogenet Genomics. 2013 Nov;23(11):627-30. doi: 10.1097/FPC.0b013e3283659a94.

PMID:
24026091
17.

Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.

González-Gugel E, Villa-Morales M, Santos J, Bueno MJ, Malumbres M, Rodríguez-Pinilla SM, Piris MÁ, Fernández-Piqueras J.

Carcinogenesis. 2013 Apr;34(4):902-8. doi: 10.1093/carcin/bgs404. Epub 2013 Jan 3.

PMID:
23288923
18.

Genetic epistasis in female suicide attempters.

Fernández-Navarro P, Vaquero-Lorenzo C, Blasco-Fontecilla H, Díaz-Hernández M, Gratacòs M, Estivill X, Costas J, Carracedo Á, Fernández-Piqueras J, Saiz-Ruiz J, Baca-Garcia E.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Aug 7;38(2):294-301. doi: 10.1016/j.pnpbp.2012.04.014. Epub 2012 Apr 23.

PMID:
22554588
19.

Targeting the Fas/FasL signaling pathway in cancer therapy.

Villa-Morales M, Fernández-Piqueras J.

Expert Opin Ther Targets. 2012 Jan;16(1):85-101. doi: 10.1517/14728222.2011.628937. Epub 2012 Jan 12. Review.

PMID:
22239437
20.

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population.

Almoguera B, Riveiro-Alvarez R, Lopez-Castroman J, Dorado P, Vaquero-Lorenzo C, Fernandez-Piqueras J, Llerena A, Abad-Santos F, Baca-García E, Dal-Ré R, Ayuso C; Spanish Consortium of Pharmacogenetics Research in Schizophrenia.

Pharmacogenomics J. 2013 Apr;13(2):197-204. doi: 10.1038/tpj.2011.57. Epub 2012 Jan 3.

21.

EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas.

López-Nieva P, Vaquero C, Fernández-Navarro P, González-Sánchez L, Villa-Morales M, Santos J, Esteller M, Fernández-Piqueras J.

Carcinogenesis. 2012 Feb;33(2):452-8. doi: 10.1093/carcin/bgr271. Epub 2011 Nov 22.

PMID:
22114070
22.

ATA homozigosity in the IL-10 gene promoter is a risk factor for schizophrenia in Spanish females: a case control study.

Almoguera B, Riveiro-Alvarez R, Lopez-Castroman J, Dorado P, Lopez-Rodriguez R, Fernandez-Navarro P, Baca-García E, Fernandez-Piqueras J, Dal-Ré R, Abad-Santos F, Llerena A, Ayuso C; Spanish Consortium of Pharmacogenetics Research in Schizophrenia.

BMC Med Genet. 2011 Jun 9;12:81. doi: 10.1186/1471-2350-12-81.

23.

Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway.

Bueno MJ, Gómez de Cedrón M, Gómez-López G, Pérez de Castro I, Di Lisio L, Montes-Moreno S, Martínez N, Guerrero M, Sánchez-Martínez R, Santos J, Pisano DG, Piris MA, Fernández-Piqueras J, Malumbres M.

Blood. 2011 Jun 9;117(23):6255-66. doi: 10.1182/blood-2010-10-315432. Epub 2011 Apr 8.

PMID:
21478429
24.

Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.

Almoguera B, Riveiro-Alvarez R, Gomez-Dominguez B, Lopez-Rodriguez R, Dorado P, Vaquero-Lorenzo C, Dal-Ré R, Fernandez-Piqueras J, Llerena A, Abad-Santos F, Ayuso C.

Pharmacogenomics. 2010 Nov;11(11):1619-25. doi: 10.2217/pgs.10.131.

25.

Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility.

Villa-Morales M, González-Gugel E, Shahbazi MN, Santos J, Fernández-Piqueras J.

Carcinogenesis. 2010 Dec;31(12):2165-71. doi: 10.1093/carcin/bgq201. Epub 2010 Oct 1.

PMID:
20889682
26.

The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas.

Santos J, González-Sánchez L, Villa-Morales M, Ors I, López-Nieva P, Vaquero C, González-Gugel E, Fernández-Navarro P, Roncero AM, Guenet JL, Montagutelli X, Fernández-Piqueras J.

Oncogene. 2010 Sep 23;29(38):5265-73. doi: 10.1038/onc.2010.280. Epub 2010 Jul 19.

PMID:
20639904
27.

Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signaling.

Bueno MJ, Gómez de Cedrón M, Laresgoiti U, Fernández-Piqueras J, Zubiaga AM, Malumbres M.

Mol Cell Biol. 2010 Jun;30(12):2983-95. doi: 10.1128/MCB.01372-09. Epub 2010 Apr 19.

28.

Nucleotide variation in central nervous system genes among male suicide attempters.

Baca-Garcia E, Vaquero-Lorenzo C, Perez-Rodriguez MM, Gratacòs M, Bayés M, Santiago-Mozos R, Leiva-Murillo JM, de Prado-Cumplido M, Artes-Rodriguez A, Ceverino A, Diaz-Sastre C, Fernandez-Navarro P, Costas J, Fernandez-Piqueras J, Diaz-Hernandez M, de Leon J, Baca-Baldomero E, Saiz-Ruiz J, Mann JJ, Parsey RV, Carracedo A, Estivill X, Oquendo MA.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):208-13. doi: 10.1002/ajmg.b.30975.

PMID:
19455598
29.

A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.

Santos J, González-Sánchez L, Matabuena-Deyzaguirre M, Villa-Morales M, Cozar P, López-Nieva P, Fernández-Navarro P, Fresno M, Díaz-Muñoz MD, Guenet JL, Montagutelli X, Fernández-Piqueras J.

Cancer Res. 2009 Mar 15;69(6):2577-87. doi: 10.1158/0008-5472.CAN-08-1821. Epub 2009 Feb 24.

30.

Gender effect on association between DRD2 polymorphism and substance dependence in a Spanish sample.

López-Castromán J, Vaquero-Lorenzo C, Perez-Rodriguez MM, Diaz-Hernandez M, Fernandez-Piqueras J, Saiz-Ruiz J, Baca-Garcia E.

Drug Alcohol Depend. 2009 May 1;101(3):210-2. doi: 10.1016/j.drugalcdep.2008.12.011. Epub 2009 Feb 13.

PMID:
19217722
31.

SAT-1 -1415T/C polymorphism and susceptibility to schizophrenia.

Bermudo-Soriano CR, Vaquero-Lorenzo C, Diaz-Hernandez M, Perez-Rodriguez MM, Fernandez-Piqueras J, Saiz-Ruiz J, Baca-Garcia E.

Prog Neuropsychopharmacol Biol Psychiatry. 2009 Mar 17;33(2):345-8. doi: 10.1016/j.pnpbp.2008.12.015. Epub 2009 Jan 3.

PMID:
19162121
32.

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A; Psychiatric Genetics Network Group.

Am J Med Genet B Neuropsychiatr Genet. 2009 Sep 5;150B(6):808-16. doi: 10.1002/ajmg.b.30902.

PMID:
19086053
33.

Genetically modified mouse models in cancer studies.

Santos J, Fernández-Navarro P, Villa-Morales M, González-Sánchez L, Fernández-Piqueras J.

Clin Transl Oncol. 2008 Dec;10(12):794-803. Review.

PMID:
19068450
34.

Positive association between SAT-1 -1415T/C polymorphism and anxiety.

Vaquero-Lorenzo C, Riaza Bermudo-Soriano C, Perez-Rodriguez MM, Diaz-Hernandez M, López-Castromán J, Fernandez-Piqueras J, Saiz-Ruiz J, Baca-Garcia E.

Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B(4):515-9. doi: 10.1002/ajmg.b.30850.

PMID:
18759322
35.

Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

Bueno MJ, Pérez de Castro I, Gómez de Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernández-Piqueras J, Malumbres M.

Cancer Cell. 2008 Jun;13(6):496-506. doi: 10.1016/j.ccr.2008.04.018. Erratum in: Cancer Cell. 2016 Apr 11;29(4):607-8.

36.

Association study of two polymorphisms of the serotonin-2A receptor gene and suicide attempts.

Vaquero-Lorenzo C, Baca-Garcia E, Diaz-Hernandez M, Perez-Rodriguez MM, Fernandez-Navarro P, Giner L, Carballo JJ, Saiz-Ruiz J, Fernandez-Piqueras J, Baldomero EB, de Leon J, Oquendo MA.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):645-9. doi: 10.1002/ajmg.b.30642.

PMID:
18163387
37.

A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.

Pérez-Gómez E, Villa-Morales M, Santos J, Fernández-Piqueras J, Gamallo C, Dotor J, Bernabéu C, Quintanilla M.

Cancer Res. 2007 Nov 1;67(21):10268-77.

38.

Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorder.

Alonso P, Gratacòs M, Menchón JM, Saiz-Ruiz J, Segalàs C, Baca-García E, Labad J, Fernández-Piqueras J, Real E, Vaquero C, Pérez M, Dolengevich H, González JR, Bayés M, de Cid R, Vallejo J, Estivill X.

Biol Psychiatry. 2008 Mar 15;63(6):619-28. Epub 2007 Sep 19.

PMID:
17884018
39.

A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.

Villa-Morales M, Santos J, Pérez-Gómez E, Quintanilla M, Fernández-Piqueras J.

Cancer Res. 2007 Jun 1;67(11):5107-16.

40.

Association between the T102C polymorphism of the serotonin-2A receptor gene and schizophrenia.

Vaquero Lorenzo C, Baca-Garcia E, Diaz-Hernandez M, Botillo-Martin C, Perez-Rodriguez MM, Fernandez-Ramos C, Saiz-Gonzalez MD, Quintero-Gutierrez FJ, Saiz-Ruiz J, Fernandez Piqueras J, Gonzalez de Rivera JL, de Leon J.

Prog Neuropsychopharmacol Biol Psychiatry. 2006 Aug 30;30(6):1136-8. Epub 2006 Jun 8.

PMID:
16762472
41.

Lack of correlation between DNA copy number and mRNA expression levels of c-myc in gamma-radiation-induced mouse thymic lymphomas by using quantitative real-time PCR.

Santos J, Vaquero C, Reyes J, López-Nieva P, Matabuena M, Villa M, Fernández P, Fernández-Piqueras J.

Clin Transl Oncol. 2006 May;8(5):349-53.

PMID:
16760010
42.

Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma.

De la Cueva E, García-Cao I, Herranz M, López P, García-Palencia P, Flores JM, Serrano M, Fernández-Piqueras J, Martín-Caballero J.

Oncogene. 2006 Jul 6;25(29):4128-32. Epub 2006 Feb 6.

PMID:
16462758
43.

Epigenetic silencing of E- and N-cadherins in the stroma of mouse thymic lymphomas.

de Yzaguirre MM, Hernández JS, Navarro PF, Nieva PL, Herranz M, Fraga MF, Esteller M, Juarranz A, Fernández-Piqueras J.

Carcinogenesis. 2006 May;27(5):1081-9. Epub 2005 Dec 24. Erratum in: Carcinogenesis. 2016 Jun;37(6):646.

PMID:
16377805
44.
45.

A pilot genetic study of the continuum between compulsivity and impulsivity in females: the serotonin transporter promoter polymorphism.

Baca-García E, Salgado BR, Segal HD, Lorenzo CV, Acosta MN, Romero MA, Hernández MD, Saiz-Ruiz J, Fernandez Piqueras J, de Leon J.

Prog Neuropsychopharmacol Biol Psychiatry. 2005 Jun;29(5):713-7.

PMID:
15908092
46.

Gene expression analysis of chromosomal regions with gain or loss of genetic material detected by comparative genomic hybridization.

Meléndez B, Díaz-Uriarte R, Cuadros M, Martínez-Ramírez A, Fernández-Piqueras J, Dopazo A, Cigudosa JC, Rivas C, Dopazo J, Martínez-Delgado B, Benítez J.

Genes Chromosomes Cancer. 2004 Dec;41(4):353-65.

PMID:
15382261
47.

New GABAA receptor alpha5 subunit gene polymorphism that may confound genotyping.

Vaquero C, Baca-Garcia E, Diaz-Sastre C, Perez-Rodriguez MM, Navio Acosta M, Saiz-Ruiz J, de Leon J, Fernandez-Piqueras J.

Am J Med Genet B Neuropsychiatr Genet. 2004 Aug 15;129B(1):27-8.

PMID:
15274034
48.

Lack of association between the serotonin transporter promoter gene polymorphism and impulsivity or aggressive behavior among suicide attempters and healthy volunteers.

Baca-Garcia E, Vaquero C, Diaz-Sastre C, García-Resa E, Saiz-Ruiz J, Fernández-Piqueras J, de Leon J.

Psychiatry Res. 2004 Apr 30;126(2):99-106.

PMID:
15123389
49.

Real-time PCR designs to estimate nuclear and mitochondrial DNA copy number in forensic and ancient DNA studies.

Alonso A, Martín P, Albarrán C, García P, García O, de Simón LF, García-Hirschfeld J, Sancho M, de La Rúa C, Fernández-Piqueras J.

Forensic Sci Int. 2004 Jan 28;139(2-3):141-9.

PMID:
15040907
50.

Defective expression of Notch1 and Notch2 in connection to alterations of c-Myc and Ikaros in gamma-radiation-induced mouse thymic lymphomas.

López-Nieva P, Santos J, Fernández-Piqueras J.

Carcinogenesis. 2004 Jul;25(7):1299-304. Epub 2004 Feb 19.

PMID:
14976135

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