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Items: 50

1.

Unchanged surface morphology in debris-covered glaciers and rock glaciers in Tröllaskagi peninsula (northern Iceland).

Tanarro LM, Palacios D, Andrés N, Fernández-Fernández JM, Zamorano JJ, Sæmundsson Þ, Brynjólfsson S.

Sci Total Environ. 2018 Aug 6;648:218-235. doi: 10.1016/j.scitotenv.2018.07.460. [Epub ahead of print] No abstract available.

PMID:
30121028
2.

Functional coupling of GABAA/B receptors and the channel TRPV4 mediates rapid progesterone signaling in the oviduct.

Jung C, Fernández-Dueñas V, Plata C, Garcia-Elias A, Ciruela F, Fernández-Fernández JM, Valverde MA.

Sci Signal. 2018 Aug 14;11(543). pii: eaam6558. doi: 10.1126/scisignal.aam6558.

PMID:
30108184
3.

Stroke-Like Episodes and Cerebellar Syndrome in Phosphomannomutase Deficiency (PMM2-CDG): Evidence for Hypoglycosylation-Driven Channelopathy.

Izquierdo-Serra M, Martínez-Monseny AF, López L, Carrillo-García J, Edo A, Ortigoza-Escobar JD, García Ó, Cancho-Candela R, Carrasco-Marina ML, Gutiérrez-Solana LG, Cuadras D, Muchart J, Montero R, Artuch R, Pérez-Cerdá C, Pérez B, Pérez-Dueñas B, Macaya A, Fernández-Fernández JM, Serrano M.

Int J Mol Sci. 2018 Feb 22;19(2). pii: E619. doi: 10.3390/ijms19020619.

4.

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

Pardo-Pastor C, Rubio-Moscardo F, Vogel-González M, Serra SA, Afthinos A, Mrkonjic S, Destaing O, Abenza JF, Fernández-Fernández JM, Trepat X, Albiges-Rizo C, Konstantopoulos K, Valverde MA.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1925-1930. doi: 10.1073/pnas.1718177115. Epub 2018 Feb 5.

5.

Cross talk between β subunits, intracellular Ca2+ signaling, and SNAREs in the modulation of CaV 2.1 channel steady-state inactivation.

Serra SA, Gené GG, Elorza-Vidal X, Fernández-Fernández JM.

Physiol Rep. 2018 Jan;6(2). doi: 10.14814/phy2.13557.

6.

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells.

Galindo L, Moreno E, López-Armenta F, Guinart D, Cuenca-Royo A, Izquierdo-Serra M, Xicota L, Fernandez C, Menoyo E, Fernández-Fernández JM, Benítez-King G, Canela EI, Casadó V, Pérez V, de la Torre R, Robledo P.

Mol Neurobiol. 2018 Aug;55(8):6347-6361. doi: 10.1007/s12035-017-0833-7. Epub 2018 Jan 2.

PMID:
29294249
7.

Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.

Berna-Erro A, Izquierdo-Serra M, Sepúlveda RV, Rubio-Moscardo F, Doñate-Macián P, Serra SA, Carrillo-Garcia J, Perálvarez-Marín A, González-Nilo F, Fernández-Fernández JM, Valverde MA.

Sci Rep. 2017 Sep 5;7(1):10522. doi: 10.1038/s41598-017-11274-1.

8.

Missense mutations of CACNA1A are a frequent cause of autosomal dominant nonprogressive congenital ataxia.

Travaglini L, Nardella M, Bellacchio E, D'Amico A, Capuano A, Frusciante R, Di Capua M, Cusmai R, Barresi S, Morlino S, Fernández-Fernández JM, Trivisano M, Specchio N, Valeriani M, Vigevano F, Bertini E, Zanni G.

Eur J Paediatr Neurol. 2017 May;21(3):450-456. doi: 10.1016/j.ejpn.2016.11.005. Epub 2016 Nov 30.

PMID:
28007337
9.

RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.

Hernandez-Muñoz I, Figuerola E, Sanchez-Molina S, Rodriguez E, Fernández-Mariño AI, Pardo-Pastor C, Bahamonde MI, Fernández-Fernández JM, García-Domínguez DJ, Hontecillas-Prieto L, Lavarino C, Carcaboso AM, de Torres C, Tirado OM, de Alava E, Mora J.

Oncotarget. 2016 Jul 19;7(29):46283-46300. doi: 10.18632/oncotarget.10092.

10.

Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.

Oliván-Viguera A, Valero MS, Pinilla E, Amor S, García-Villalón ÁL, Coleman N, Laría C, Calvín-Tienza V, García-Otín ÁL, Fernández-Fernández JM, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Badorrey R, Simonsen U, Rivera L, Wulff H, Köhler R.

Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92. doi: 10.1111/bcpt.12560. Epub 2016 Feb 29.

11.

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx.

Bahamonde MI, Serra SA, Drechsel O, Rahman R, Marcé-Grau A, Prieto M, Ossowski S, Macaya A, Fernández-Fernández JM.

PLoS One. 2015 Dec 30;10(12):e0146035. doi: 10.1371/journal.pone.0146035. eCollection 2015.

12.

Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.

Fernández-Mariño AI, Cidad P, Zafra D, Nocito L, Domínguez J, Oliván-Viguera A, Köhler R, López-López JR, Pérez-García MT, Valverde MÁ, Guinovart JJ, Fernández-Fernández JM.

PLoS One. 2015 Feb 6;10(2):e0118148. doi: 10.1371/journal.pone.0118148. eCollection 2015.

13.

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors.

Grau C, Arató K, Fernández-Fernández JM, Valderrama A, Sindreu C, Fillat C, Ferrer I, de la Luna S, Altafaj X.

Front Cell Neurosci. 2014 Oct 17;8:331. doi: 10.3389/fncel.2014.00331. eCollection 2014.

14.

Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.

Carreño O, Corominas R, Serra SA, Sintas C, Fernández-Castillo N, Vila-Pueyo M, Toma C, Gené GG, Pons R, Llaneza M, Sobrido MJ, Grinberg D, Valverde MÁ, Fernández-Fernández JM, Macaya A, Cormand B.

Mol Genet Genomic Med. 2013 Nov;1(4):206-22. doi: 10.1002/mgg3.24. Epub 2013 Jul 2.

15.

A loss-of-function CACNA1A mutation causing benign paroxysmal torticollis of infancy.

Vila-Pueyo M, Gené GG, Flotats-Bastardes M, Elorza X, Sintas C, Valverde MA, Cormand B, Fernández-Fernández JM, Macaya A.

Eur J Paediatr Neurol. 2014 May;18(3):430-3. doi: 10.1016/j.ejpn.2013.12.011. Epub 2014 Jan 8.

PMID:
24445160
16.

BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.

Fernández-Mariño AI, Valverde MA, Fernández-Fernández JM.

Pflugers Arch. 2014 Jul;466(7):1365-75. doi: 10.1007/s00424-013-1379-9. Epub 2013 Oct 26.

PMID:
24158430
17.

Bile duct adenoma (hamartoma of peribiliary glands): Importance of an adequate diagnosis.

Fernández Fernández JM, Muriel Cueto P, Sánchez Sánchez AM, Dulanto Vargas M, Bados Nieto P.

Cir Esp. 2015 Oct;93(8):e95-6. doi: 10.1016/j.ciresp.2013.06.017. Epub 2013 Oct 11. English, Spanish. No abstract available.

PMID:
24125022
18.

TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.

Mitrovic S, Nogueira C, Cantero-Recasens G, Kiefer K, Fernández-Fernández JM, Popoff JF, Casano L, Bard FA, Gomez R, Valverde MA, Malhotra V.

Elife. 2013 May 28;2:e00658. doi: 10.7554/eLife.00658.

19.

Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation.

Fernández-Mariño AI, Porras-González C, González-Rodríguez P, Selent J, Pastor M, Ureña J, Castellano A, Valverde MA, Fernández-Fernández JM.

Cardiovasc Res. 2012 Jul 1;95(1):29-38. doi: 10.1093/cvr/cvs139. Epub 2012 Apr 2.

PMID:
22473360
20.

SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.

Carreño O, Corominas R, Fernández-Morales J, Camiña M, Sobrido MJ, Fernández-Fernández JM, Pozo-Rosich P, Cormand B, Macaya A.

Am J Med Genet B Neuropsychiatr Genet. 2012 Jan;159B(1):94-103. doi: 10.1002/ajmg.b.32007. Epub 2011 Dec 7.

PMID:
22162417
21.

A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis.

Weiss N, Hameed S, Fernández-Fernández JM, Fablet K, Karmazinova M, Poillot C, Proft J, Chen L, Bidaud I, Monteil A, Huc-Brandt S, Lacinova L, Lory P, Zamponi GW, De Waard M.

J Biol Chem. 2012 Jan 20;287(4):2810-8. doi: 10.1074/jbc.M111.290882. Epub 2011 Nov 30.

22.

A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.

Serra SA, Cuenca-León E, Llobet A, Rubio-Moscardo F, Plata C, Carreño O, Fernàndez-Castillo N, Corominas R, Valverde MA, Macaya A, Cormand B, Fernández-Fernández JM.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1672-7. doi: 10.1073/pnas.0908359107. Epub 2010 Jan 8.

23.

KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating.

Solé L, Roura-Ferrer M, Pérez-Verdaguer M, Oliveras A, Calvo M, Fernández-Fernández JM, Felipe A.

J Cell Sci. 2009 Oct 15;122(Pt 20):3738-48. doi: 10.1242/jcs.056689. Epub 2009 Sep 22.

24.

A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia.

Tian W, Fu Y, Garcia-Elias A, Fernández-Fernández JM, Vicente R, Kramer PL, Klein RF, Hitzemann R, Orwoll ES, Wilmot B, McWeeney S, Valverde MA, Cohen DM.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14034-9. doi: 10.1073/pnas.0904084106. Epub 2009 Aug 4.

25.

Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population.

Corominas R, Ribasés M, Cuenca-León E, Narberhaus B, Serra SA, del Toro M, Roig M, Fernández-Fernández JM, Macaya A, Cormand B.

Neurosci Lett. 2009 May 15;455(2):105-9. doi: 10.1016/j.neulet.2009.03.011. Epub 2009 Mar 6.

PMID:
19368856
26.

Late-onset episodic ataxia type 2 associated with a novel loss-of-function mutation in the CACNA1A gene.

Cuenca-León E, Banchs I, Serra SA, Latorre P, Fernàndez-Castillo N, Corominas R, Valverde MA, Volpini V, Fernández-Fernández JM, Macaya A, Cormand B.

J Neurol Sci. 2009 May 15;280(1-2):10-4. doi: 10.1016/j.jns.2009.01.005. Epub 2009 Feb 20.

PMID:
19232643
27.

The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition.

Serra SA, Fernàndez-Castillo N, Macaya A, Cormand B, Valverde MA, Fernández-Fernández JM.

Pflugers Arch. 2009 Jul;458(3):489-502. doi: 10.1007/s00424-009-0637-3. Epub 2009 Feb 3.

PMID:
19189122
28.

Genetic variation in the KCNMA1 potassium channel alpha subunit as risk factor for severe essential hypertension and myocardial infarction.

Tomás M, Vázquez E, Fernández-Fernández JM, Subirana I, Plata C, Heras M, Vila J, Marrugat J, Valverde MA, Sentí M.

J Hypertens. 2008 Nov;26(11):2147-53. doi: 10.1097/HJH.0b013e32831103d8.

PMID:
18854754
29.

Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines.

Fernández-Fernández JM, Andrade YN, Arniges M, Fernandes J, Plata C, Rubio-Moscardo F, Vázquez E, Valverde MA.

Pflugers Arch. 2008 Oct;457(1):149-59. doi: 10.1007/s00424-008-0516-3. Epub 2008 May 6.

PMID:
18458941
30.

IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.

Fernandes J, Lorenzo IM, Andrade YN, Garcia-Elias A, Serra SA, Fernández-Fernández JM, Valverde MA.

J Gen Physiol. 2008 May;131(5):i2. doi: 10.1085/JGP1315OIA2.

31.

IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.

Fernandes J, Lorenzo IM, Andrade YN, Garcia-Elias A, Serra SA, Fernández-Fernández JM, Valverde MA.

J Cell Biol. 2008 Apr 7;181(1):143-55. doi: 10.1083/jcb.200712058. Epub 2008 Mar 31.

32.

Association between self-replicating calcifying nanoparticles and aortic stenosis: a possible link to valve calcification.

Bratos-Pérez MA, Sánchez PL, García de Cruz S, Villacorta E, Palacios IF, Fernández-Fernández JM, Di Stefano S, Orduña-Domingo A, Carrascal Y, Mota P, Martín-Luengo C, Bermejo J, San Roman JA, Rodríguez-Torres A, Fernández-Avilés F; Grupo AORTICA (Grupo de Estudio de la Estenosis Aórtica).

Eur Heart J. 2008 Feb;29(3):371-6. doi: 10.1093/eurheartj/ehm592. Epub 2008 Jan 12.

PMID:
18192703
33.

Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk.

Sentí M, Fernández-Fernández JM, Tomás M, Vázquez E, Elosua R, Marrugat J, Valverde MA.

Circ Res. 2005 Dec 9;97(12):1360-5. Epub 2005 Nov 17.

PMID:
16293791
34.

Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking.

Arniges M, Fernández-Fernández JM, Albrecht N, Schaefer M, Valverde MA.

J Biol Chem. 2006 Jan 20;281(3):1580-6. Epub 2005 Nov 16. Erratum in: J Biol Chem. 2006 Mar 31;281(13):8996.

35.

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity.

Andrade YN, Fernandes J, Vázquez E, Fernández-Fernández JM, Arniges M, Sánchez TM, Villalón M, Valverde MA.

J Cell Biol. 2005 Mar 14;168(6):869-74. Epub 2005 Mar 7.

36.

Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia.

Arniges M, Vázquez E, Fernández-Fernández JM, Valverde MA.

J Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15.

37.

Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors.

Filippov AK, Fernández-Fernández JM, Marsh SJ, Simon J, Barnard EA, Brown DA.

Mol Pharmacol. 2004 Sep;66(3):468-77.

38.

Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension.

Fernández-Fernández JM, Tomás M, Vázquez E, Orio P, Latorre R, Sentí M, Marrugat J, Valverde MA.

J Clin Invest. 2004 Apr;113(7):1032-9.

39.

Plasma membrane voltage-dependent anion channel mediates antiestrogen-activated maxi Cl- currents in C1300 neuroblastoma cells.

Bahamonde MI, Fernández-Fernández JM, Guix FX, Vázquez E, Valverde MA.

J Biol Chem. 2003 Aug 29;278(35):33284-9. Epub 2003 Jun 5.

40.

Maxi K+ channel mediates regulatory volume decrease response in a human bronchial epithelial cell line.

Fernández-Fernández JM, Nobles M, Currid A, Vázquez E, Valverde MA.

Am J Physiol Cell Physiol. 2002 Dec;283(6):C1705-14. Epub 2002 Aug 14.

41.

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2.

Delmas P, Nomura H, Li X, Lakkis M, Luo Y, Segal Y, Fernández-Fernández JM, Harris P, Frischauf AM, Brown DA, Zhou J.

J Biol Chem. 2002 Mar 29;277(13):11276-83. Epub 2002 Jan 10.

42.
43.

Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4.

Haley JE, Abogadie FC, Fernandez-Fernandez JM, Dayrell M, Vallis Y, Buckley NJ, Brown DA.

J Neurosci. 2000 Nov 1;20(21):RC105.

44.

Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones.

Fernandez-Fernandez JM, Wanaverbecq N, Halley P, Caulfield MP, Brown DA.

J Physiol. 1999 Mar 15;515 ( Pt 3):631-7.

45.

Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells.

Izaguirre V, Fernández-Fernández JM, Ceña V, González-García C.

FEBS Lett. 1997 Nov 24;418(1-2):39-42.

46.

omega-Agatoxin IVA blocks nicotinic receptor channels in bovine chromaffin cells.

Granja R, Fernández-Fernández JM, Izaguirre V, González-García C, Ceña V.

FEBS Lett. 1995 Mar 27;362(1):15-8.

47.

Effect of insulin and carbenoxolone on adrenaline stimulated lipolysis in human lipoma.

Gómez-Capilla JA, Amaya F, López-Cantarero M, Fernández-Fernández JM.

Horm Metab Res. 1990 Oct;22(10):551-2. No abstract available.

PMID:
2079320
48.

Effect of carbenoxolone on glucose metabolism in rat adipose tissue.

Gomez-Capilla JA, Gutierrez C, Fernández-Fernández JM.

Biochem Pharmacol. 1988 Apr 1;37(7):1299-301.

PMID:
2833277
49.

Effect of insulin in vivo on the synthesis of free fatty acids (FFA) in chicken heart and skeletal muscle.

Gomez-Capilla JA, Sancho J, Fernandez-Fernandez JM, Osorio C.

Experientia. 1980 May 15;36(5):611-2.

PMID:
6991278
50.

Effect of carbenoxolone on lipolysis in chicken adipose tissue.

Fernández-Fernández JM, Vives F, Gómez-Capilla JA.

Horm Metab Res. 1980 May;12(5):221-2. No abstract available.

PMID:
7390403

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