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Items: 21

1.

Soluble ST2 promotes oxidative stress and inflammation in cardiac fibroblasts: An in vitro and in vivo study in aortic stenosis.

Matilla L, Ibarrola J, Arrieta V, Garcia-Peña A, Martinez-Martinez E, Sádaba R, Alvarez V, Navarro A, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Bayes-Genis A, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2019 Jul 8. pii: CS20190475. doi: 10.1042/CS20190475. [Epub ahead of print]

PMID:
31285364
2.

Myocardial Injury After Ischemia/Reperfusion Is Attenuated By Pharmacological Galectin-3 Inhibition.

Ibarrola J, Matilla L, Martínez-Martínez E, Gueret A, Fernández-Celis A, Henry JP, Nicol L, Jaisser F, Mulder P, Ouvrard-Pascaud A, López-Andrés N.

Sci Rep. 2019 Jul 3;9(1):9607. doi: 10.1038/s41598-019-46119-6.

3.

CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation.

Martínez-Martínez E, Brugnolaro C, Ibarrola J, Ravassa S, Buonafine M, López B, Fernández-Celis A, Querejeta R, Santamaria E, Fernández-Irigoyen J, Rábago G, Moreno MU, Jaisser F, Díez J, González A, López-Andrés N.

Hypertension. 2019 Mar;73(3):602-611. doi: 10.1161/HYPERTENSIONAHA.118.11874.

PMID:
30612490
4.

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure.

Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ.

Mol Ther. 2019 Mar 6;27(3):584-599. doi: 10.1016/j.ymthe.2018.11.011. Epub 2018 Nov 17.

5.

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.

Ibarrola J, Sadaba R, Martinez-Martinez E, Garcia-Peña A, Arrieta V, Alvarez V, Fernández-Celis A, Gainza A, Cachofeiro V, Santamaria E, Fernandez-Irigoyen J, Jaisser F, Lopez-Andres N.

Sci Rep. 2018 May 1;8(1):6801. doi: 10.1038/s41598-018-25068-6.

6.

Galectin-3 down-regulates antioxidant peroxiredoxin-4 in human cardiac fibroblasts: a new pathway to induce cardiac damage.

Ibarrola J, Arrieta V, Sádaba R, Martinez-Martinez E, Garcia-Peña A, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Zalba G, Fay R, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2018 Jul 18;132(13):1471-1485. doi: 10.1042/CS20171389. Print 2018 Jul 18.

PMID:
29674526
7.

A role for fumarate hydratase in mediating oxidative effects of galectin-3 in human cardiac fibroblasts.

Ibarrola J, Sádaba R, Garcia-Peña A, Arrieta V, Martinez-Martinez E, Alvarez V, Fernández-Celis A, Gainza A, Santamaría E, Fernández-Irigoyen J, Cachofeiro V, Fay R, Rossignol P, López-Andrés N.

Int J Cardiol. 2018 May 1;258:217-223. doi: 10.1016/j.ijcard.2017.12.103.

PMID:
29544935
8.

Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor.

Mesquita TR, Auguste G, Falcón D, Ruiz-Hurtado G, Salazar-Enciso R, Sabourin J, Lefebvre F, Viengchareun S, Kobeissy H, Lechène P, Nicolas V, Fernandez-Celis A, Gómez S, Lauton Santos S, Morel E, Rueda A, López-Andrés N, Gómez AM, Lombès M, Benitah JP.

Circ Res. 2018 Mar 30;122(7):e49-e61. doi: 10.1161/CIRCRESAHA.117.312451. Epub 2018 Feb 21.

PMID:
29467196
9.

Neutrophil Gelatinase-Associated Lipocalin from immune cells is mandatory for aldosterone-induced cardiac remodeling and inflammation.

Buonafine M, Martínez-Martínez E, Amador C, Gravez B, Ibarrola J, Fernández-Celis A, El Moghrabi S, Rossignol P, López-Andrés N, Jaisser F.

J Mol Cell Cardiol. 2018 Feb;115:32-38. doi: 10.1016/j.yjmcc.2017.12.011. Epub 2017 Dec 28.

PMID:
29289651
10.

Aldosterone Target NGAL (Neutrophil Gelatinase-Associated Lipocalin) Is Involved in Cardiac Remodeling After Myocardial Infarction Through NFκB Pathway.

Martínez-Martínez E, Buonafine M, Boukhalfa I, Ibarrola J, Fernández-Celis A, Kolkhof P, Rossignol P, Girerd N, Mulder P, López-Andrés N, Ouvrard-Pascaud A, Jaisser F.

Hypertension. 2017 Dec;70(6):1148-1156. doi: 10.1161/HYPERTENSIONAHA.117.09791. Epub 2017 Oct 23.

PMID:
29061727
11.

Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts.

Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Santamaria E, Fernández-Irigoyen J, Rossignol P, Jaisser F, López-Andrés N.

Sci Rep. 2017 Sep 22;7(1):12192. doi: 10.1038/s41598-017-12305-7.

12.

Galectin-3 pharmacological inhibition attenuates early renal damage in spontaneously hypertensive rats.

Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Calvier L, Leroy C, Cachofeiro V, Rossignol P, López-Andrés N.

J Hypertens. 2018 Feb;36(2):368-376. doi: 10.1097/HJH.0000000000001545.

PMID:
28858976
13.

Beneficial Effects of Galectin-3 Blockade in Vascular and Aortic Valve Alterations in an Experimental Pressure Overload Model.

Ibarrola J, Martínez-Martínez E, Sádaba JR, Arrieta V, García-Peña A, Álvarez V, Fernández-Celis A, Gainza A, Rossignol P, Cachofeiro Ramos V, López-Andrés N.

Int J Mol Sci. 2017 Jul 31;18(8). pii: E1664. doi: 10.3390/ijms18081664.

14.

Differential proteomics reveals S100-A11 as a key factor in aldosterone-induced collagen expression in human cardiac fibroblasts.

Martínez-Martínez E, Ibarrola J, Lachén-Montes M, Fernández-Celis A, Jaisser F, Santamaría E, Fernández-Irigoyen J, López-Andrés N.

J Proteomics. 2017 Aug 23;166:93-100. doi: 10.1016/j.jprot.2017.07.011. Epub 2017 Jul 22.

PMID:
28739510
15.

A role for galectin-3 in the development of early molecular alterations in short-term aortic stenosis.

Arrieta V, Martinez-Martinez E, Ibarrola J, Alvarez V, Sádaba R, Garcia-Peña A, Fernández-Celis A, Cachofeiro V, Rossignol P, López-Andrés N.

Clin Sci (Lond). 2017 May 1;131(10):935-949. doi: 10.1042/CS20170145. Epub 2017 Mar 30.

PMID:
28360193
16.

Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage.

Martinez-Martinez E, Ibarrola J, Calvier L, Fernandez-Celis A, Leroy C, Cachofeiro V, Rossignol P, Lopez-Andres N.

PLoS One. 2016 Nov 9;11(11):e0166272. doi: 10.1371/journal.pone.0166272. eCollection 2016.

17.

Role for Galectin-3 in Calcific Aortic Valve Stenosis.

Sádaba JR, Martínez-Martínez E, Arrieta V, Álvarez V, Fernández-Celis A, Ibarrola J, Melero A, Rossignol P, Cachofeiro V, López-Andrés N.

J Am Heart Assoc. 2016 Nov 4;5(11). pii: e004360.

18.

Galectin-3 inhibition prevents adipose tissue remodelling in obesity.

Martínez-Martínez E, Calvier L, Rossignol P, Rousseau E, Fernández-Celis A, Jurado-López R, Laville M, Cachofeiro V, López-Andrés N.

Int J Obes (Lond). 2016 Jun;40(6):1034-8. doi: 10.1038/ijo.2016.19. Epub 2016 Feb 8.

PMID:
26853916
19.

Galectin-3 Participates in Cardiovascular Remodeling Associated With Obesity.

Martínez-Martínez E, López-Ándres N, Jurado-López R, Rousseau E, Bartolomé MV, Fernández-Celis A, Rossignol P, Islas F, Antequera A, Prieto S, Luaces M, Cachofeiro V.

Hypertension. 2015 Nov;66(5):961-9. doi: 10.1161/HYPERTENSIONAHA.115.06032. Epub 2015 Sep 8.

PMID:
26351031
20.

Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension.

Martínez-Martínez E, Calvier L, Fernández-Celis A, Rousseau E, Jurado-López R, Rossoni LV, Jaisser F, Zannad F, Rossignol P, Cachofeiro V, López-Andrés N.

Hypertension. 2015 Oct;66(4):767-75. doi: 10.1161/HYPERTENSIONAHA.115.05876. Epub 2015 Aug 3.

PMID:
26238446
21.

Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation.

Martínez-Martínez E, Cachofeiro V, Rousseau E, Álvarez V, Calvier L, Fernández-Celis A, Leroy C, Miana M, Jurado-López R, Briones AM, Jaisser F, Zannad F, Rossignol P, López-Andrés N.

Mol Cell Endocrinol. 2015 Aug 15;411:20-7. doi: 10.1016/j.mce.2015.04.007. Epub 2015 Apr 17.

PMID:
25896545

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