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Items: 1 to 50 of 51

1.

Timing in the treatment of status epilepticus: From basics to the clinic.

Gaínza-Lein M, Fernández IS, Ulate-Campos A, Loddenkemper T, Ostendorf AP.

Seizure. 2018 Jun 1. pii: S1059-1311(18)30235-8. doi: 10.1016/j.seizure.2018.05.021. [Epub ahead of print] Review.

PMID:
29884518
2.

Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.

Pisareva VP, Pisarev AV, Fernández IS.

Elife. 2018 Jun 1;7. pii: e34062. doi: 10.7554/eLife.34062.

3.

Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus.

Arya R, Peariso K, Gaínza-Lein M, Harvey J, Bergin A, Brenton JN, Burrows BT, Glauser T, Goodkin HP, Lai YC, Mikati MA, Fernández IS, Tchapyjnikov D, Wilfong AA, Williams K, Loddenkemper T; pediatric Status Epilepticus Research Group (pSERG).

Epilepsy Res. 2018 Aug;144:1-6. doi: 10.1016/j.eplepsyres.2018.04.012. Epub 2018 Apr 27.

PMID:
29727818
4.

Cognitive and Behavioral Comorbidities: An Unwanted Effect of Antiepileptic Drugs in Children.

Ulate-Campos A, Fernández IS.

Semin Pediatr Neurol. 2017 Nov;24(4):320-330. doi: 10.1016/j.spen.2017.10.011. Epub 2017 Dec 6. Review.

PMID:
29249512
5.

Hypertension and frailty in older adults.

Aprahamian I, Sassaki E, Dos Santos MF, Izbicki R, Pulgrossi RC, Biella MM, Borges ACN, Sassaki MM, Torres LM, Fernandez ÍS, Pião OA, Castro PLM, Fontenele PA, Yassuda MS.

J Clin Hypertens (Greenwich). 2018 Jan;20(1):186-192. doi: 10.1111/jch.13135. Epub 2017 Nov 5.

6.

Diagnostic and Therapeutic Management of a First Unprovoked Seizure in Children and Adolescents With a Focus on the Revised Diagnostic Criteria for Epilepsy.

Sansevere AJ, Avalone J, Strauss LD, Patel AA, Pinto A, Ramachandran M, Fernandez IS, Bergin AM, Kimia A, Pearl PL, Loddenkemper T.

J Child Neurol. 2017 Jul;32(8):774-788. doi: 10.1177/0883073817706028. Epub 2017 May 14. Review.

PMID:
28503985
7.

Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.

Wong W, Bai XC, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SHW, Baum J.

Nat Microbiol. 2017 Mar 13;2:17031. doi: 10.1038/nmicrobiol.2017.31.

8.

Introduction of Basic Dermatologic Ultrasound in Undergraduate Medical Education.

Alfageme F, Cerezo E, Fernandez IS, Aguilo R, Vilas-Sueiro A, Roustan G.

Ultrasound Int Open. 2016 Nov;2(4):E136-E139.

9.

Automated seizure detection systems and their effectiveness for each type of seizure.

Ulate-Campos A, Coughlin F, Gaínza-Lein M, Fernández IS, Pearl PL, Loddenkemper T.

Seizure. 2016 Aug;40:88-101. doi: 10.1016/j.seizure.2016.06.008. Epub 2016 Jun 17. Review.

10.

Clobazam higher-evening differential dosing as an add-on therapy in refractory epilepsy.

Thome-Souza S, Klehm J, Jackson M, Kadish NE, Manganaro S, Fernández IS, Loddenkemper T.

Seizure. 2016 Aug;40:1-6. doi: 10.1016/j.seizure.2016.05.014. Epub 2016 May 27.

11.

Ribosome-dependent activation of stringent control.

Brown A, Fernández IS, Gordiyenko Y, Ramakrishnan V.

Nature. 2016 Jun 9;534(7606):277-280. doi: 10.1038/nature17675. Epub 2016 May 9.

12.

Structural characterization of ribosome recruitment and translocation by type IV IRES.

Murray J, Savva CG, Shin BS, Dever TE, Ramakrishnan V, Fernández IS.

Elife. 2016 May 9;5. pii: e13567. doi: 10.7554/eLife.13567.

13.

Negative myoclonus in a child with anti-NMDA receptor encephalitis.

Li X, Wu D, Fernández IS, Chen J, Jin P, Zhou Z, Wu Y, Jiao J, Ren L.

J Neurol Sci. 2015 Nov 15;358(1-2):532-4. doi: 10.1016/j.jns.2015.10.006. Epub 2015 Oct 9. No abstract available.

PMID:
26474794
14.

Structural changes enable start codon recognition by the eukaryotic translation initiation complex.

Hussain T, Llácer JL, Fernández IS, Munoz A, Martin-Marcos P, Savva CG, Lorsch JR, Hinnebusch AG, Ramakrishnan V.

Cell. 2014 Oct 23;159(3):597-607. doi: 10.1016/j.cell.2014.10.001. Epub 2014 Oct 16.

15.

Localization of sleep spindles, k-complexes, and vertex waves with subdural electrodes in children.

Pinto AL, Fernández IS, Peters JM, Manganaro S, Singer JM, Vendrame M, Prabhu SP, Loddenkemper T, Kothare SV.

J Clin Neurophysiol. 2014 Aug;31(4):367-74. doi: 10.1097/WNP.0000000000000071.

PMID:
25083850
16.

Structure of the mammalian ribosome-Sec61 complex to 3.4 Å resolution.

Voorhees RM, Fernández IS, Scheres SH, Hegde RS.

Cell. 2014 Jun 19;157(7):1632-43. doi: 10.1016/j.cell.2014.05.024. Epub 2014 Jun 12.

17.

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.

Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH.

Elife. 2014 Jun 9;3. doi: 10.7554/eLife.03080.

18.

Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome.

Fernández IS, Bai XC, Murshudov G, Scheres SH, Ramakrishnan V.

Cell. 2014 May 8;157(4):823-31. doi: 10.1016/j.cell.2014.04.015. Epub 2014 May 1.

19.

Insult to injury: transient encephalopathy in a brain-injured adolescent.

Peters JM, Fernández IS.

J Paediatr Child Health. 2014 May;50(5):411-4. doi: 10.1111/jpc.12471. Epub 2013 Dec 23.

PMID:
24372698
20.

Electrocorticography for seizure foci mapping in epilepsy surgery.

Fernández IS, Loddenkemper T.

J Clin Neurophysiol. 2013 Dec;30(6):554-70. doi: 10.1097/01.wnp.0000436898.10125.70. Review.

PMID:
24300981
21.

Molecular architecture of a eukaryotic translational initiation complex.

Fernández IS, Bai XC, Hussain T, Kelley AC, Lorsch JR, Ramakrishnan V, Scheres SHW.

Science. 2013 Nov 15;342(6160):1240585. doi: 10.1126/science.1240585. Epub 2013 Nov 7.

22.

Fine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlations.

Ruiz FM, Fernández IS, López-Merino L, Lagartera L, Kaltner H, Menéndez M, André S, Solís D, Gabius HJ, Romero A.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1665-76. doi: 10.1107/S0907444913011773. Epub 2013 Aug 15.

23.

Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.

Nieto L, Canales Á, Fernández IS, Santillana E, González-Corrochano R, Redondo-Horcajo M, Cañada FJ, Nieto P, Martín-Lomas M, Giménez-Gallego G, Jiménez-Barbero J.

Chembiochem. 2013 Sep 23;14(14):1732-44. doi: 10.1002/cbic.201300313. Epub 2013 Aug 12.

PMID:
23940086
24.

The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.

Arnaudo N, Fernández IS, McLaughlin SH, Peak-Chew SY, Rhodes D, Martino F.

Nat Struct Mol Biol. 2013 Sep;20(9):1119-21. doi: 10.1038/nsmb.2641. Epub 2013 Aug 11.

25.

The ribosome triggers the stringent response by RelA via a highly distorted tRNA.

Agirrezabala X, Fernández IS, Kelley AC, Cartón DG, Ramakrishnan V, Valle M.

EMBO Rep. 2013 Sep;14(9):811-6. doi: 10.1038/embor.2013.106. Epub 2013 Jul 23.

26.

Elongation factor G bound to the ribosome in an intermediate state of translocation.

Tourigny DS, Fernández IS, Kelley AC, Ramakrishnan V.

Science. 2013 Jun 28;340(6140):1235490. doi: 10.1126/science.1235490.

27.

Unusual base pairing during the decoding of a stop codon by the ribosome.

Fernández IS, Ng CL, Kelley AC, Wu G, Yu YT, Ramakrishnan V.

Nature. 2013 Aug 1;500(7460):107-10. doi: 10.1038/nature12302. Epub 2013 Jun 30.

28.

Electrographic seizures in pediatric ICU patients: cohort study of risk factors and mortality.

Abend NS, Arndt DH, Carpenter JL, Chapman KE, Cornett KM, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Lerner JT, Loddenkemper T, Matsumoto JH, McBain K, Nash KB, Payne E, Sánchez SM, Fernández IS, Shults J, Williams K, Yang A, Dlugos DJ.

Neurology. 2013 Jul 23;81(4):383-91. doi: 10.1212/WNL.0b013e31829c5cfe. Epub 2013 Jun 21.

29.

Intravenous ketamine for the treatment of refractory status epilepticus: a retrospective multicenter study.

Gaspard N, Foreman B, Judd LM, Brenton JN, Nathan BR, McCoy BM, Al-Otaibi A, Kilbride R, Fernández IS, Mendoza L, Samuel S, Zakaria A, Kalamangalam GP, Legros B, Szaflarski JP, Loddenkemper T, Hahn CD, Goodkin HP, Claassen J, Hirsch LJ, Laroche SM.

Epilepsia. 2013 Aug;54(8):1498-503. doi: 10.1111/epi.12247. Epub 2013 Jun 12.

30.

Visual aids to medical data and computational diagnostics: new frontiers in pediatric neurology.

Mane KK, Loddenkemper T, Fernández IS, Mikati MA, Tennison M, Schmitt C, Wilhelmsen K, Leviton A.

Epilepsy Behav. 2013 Aug;28(2):258-60. doi: 10.1016/j.yebeh.2013.04.014. Epub 2013 Jun 4. No abstract available.

PMID:
23756296
31.

Crystal structure of a bioactive pactamycin analog bound to the 30S ribosomal subunit.

Tourigny DS, Fernández IS, Kelley AC, Vakiti RR, Chattopadhyay AK, Dorich S, Hanessian S, Ramakrishnan V.

J Mol Biol. 2013 Oct 23;425(20):3907-10. doi: 10.1016/j.jmb.2013.05.004. Epub 2013 May 20.

32.

Electroencephalography in the pediatric emergency department: when is it most useful?

Fernández IS, Loddenkemper T, Datta A, Kothare S, Riviello JJ Jr, Rotenberg A.

J Child Neurol. 2014 Apr;29(4):475-82. doi: 10.1177/0883073813483570. Epub 2013 Apr 16.

PMID:
23594820
33.

Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity.

Peters JM, Taquet M, Vega C, Jeste SS, Fernández IS, Tan J, Nelson CA 3rd, Sahin M, Warfield SK.

BMC Med. 2013 Feb 27;11:54. doi: 10.1186/1741-7015-11-54.

34.

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles.

Bai XC, Fernandez IS, McMullan G, Scheres SH.

Elife. 2013 Feb 19;2:e00461. doi: 10.7554/eLife.00461.

35.

Signal subspace integration for improved seizure localization.

Stamoulis C, Fernández IS, Chang BS, Loddenkemper T.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:1016-9. doi: 10.1109/EMBC.2012.6346106.

36.

The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America.

Fernández IS, Chapman KE, Peters JM, Kothare SV, Nordli DR Jr, Jensen FE, Berg AT, Loddenkemper T.

Epilepsia. 2013 Apr;54(4):741-50. doi: 10.1111/epi.12039. Epub 2012 Nov 16.

37.

Dacrystic seizures: demographic, semiologic, and etiologic insights from a multicenter study in long-term video-EEG monitoring units.

Blumberg J, Fernández IS, Vendrame M, Oehl B, Tatum WO, Schuele S, Alexopoulos AV, Poduri A, Kellinghaus C, Schulze-Bonhage A, Loddenkemper T.

Epilepsia. 2012 Oct;53(10):1810-9. doi: 10.1111/j.1528-1167.2012.03578.x. Epub 2012 Jul 10.

38.

Clinical staging and electroencephalographic evolution of continuous spikes and waves during sleep.

Fernández IS, Peters JM, Hadjiloizou S, Prabhu SP, Zarowski M, Stannard KM, Takeoka M, Rotenberg A, Kothare SV, Loddenkemper T.

Epilepsia. 2012 Jul;53(7):1185-95. doi: 10.1111/j.1528-1167.2012.03507.x. Epub 2012 May 11.

39.

Patients with electrical status epilepticus in sleep share similar clinical features regardless of their focal or generalized sleep potentiation of epileptiform activity.

Fernández IS, Peters J, Takeoka M, Rotenberg A, Prabhu S, Gregas M, Riviello JJ Jr, Kothare S, Loddenkemper T.

J Child Neurol. 2013 Jan;28(1):83-9. doi: 10.1177/0883073812440507. Epub 2012 Apr 24.

PMID:
22532549
40.

A severe valproate overdose with complete recovery in a newborn.

Grynnerup A, Fernández IS, Hernández JC, Martínez AD, López JM, García-Alix A.

J Child Neurol. 2012 Aug;27(8):1072-6. doi: 10.1177/0883073811431497. Epub 2012 Mar 20.

PMID:
22433424
41.

Identification of a eukaryotic reductive dechlorinase and characterization of its mechanism of action on its natural substrate.

Velazquez F, Peak-Chew SY, Fernández IS, Neumann CS, Kay RR.

Chem Biol. 2011 Oct 28;18(10):1252-60. doi: 10.1016/j.chembiol.2011.08.003.

42.

Continuous spike and waves during sleep and electrical status epilepticus in sleep.

Loddenkemper T, Fernández IS, Peters JM.

J Clin Neurophysiol. 2011 Apr;28(2):154-64. doi: 10.1097/WNP.0b013e31821213eb. Review.

PMID:
21399511
43.

The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.

Arias-Palomo E, Yamashita A, Fernández IS, Núñez-Ramírez R, Bamba Y, Izumi N, Ohno S, Llorca O.

Genes Dev. 2011 Jan 15;25(2):153-64. doi: 10.1101/gad.606911.

44.

Pseudoverrucous irritant peristomal dermatitis with an histological pattern of nutritional deficiency dermatitis.

Fernández IS, Moreno C, Vano-Galvan S, Olasolo PJ.

Dermatol Online J. 2010 Sep 15;16(9):16.

45.

Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex.

Fernández IS, Yamashita A, Arias-Palomo E, Bamba Y, Bartolomé RA, Canales MA, Teixidó J, Ohno S, Llorca O.

Nucleic Acids Res. 2011 Jan;39(1):347-58. doi: 10.1093/nar/gkq749. Epub 2010 Sep 3.

46.

Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.

Fernández IS, Cuevas P, Angulo J, López-Navajas P, Canales-Mayordomo A, González-Corrochano R, Lozano RM, Valverde S, Jiménez-Barbero J, Romero A, Giménez-Gallego G.

J Biol Chem. 2010 Apr 9;285(15):11714-29. doi: 10.1074/jbc.M109.064618. Epub 2010 Feb 9.

47.

Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase.

Fernández IS, Ruíz-Dueñas FJ, Santillana E, Ferreira P, Martínez MJ, Martínez AT, Romero A.

Acta Crystallogr D Biol Crystallogr. 2009 Nov;65(Pt 11):1196-205. doi: 10.1107/S0907444909035860. Epub 2009 Oct 22.

PMID:
19923715
48.

Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6).

Fernández IS, Ständker L, Mägert HJ, Forssmann WG, Giménez-Gallego G, Romero A.

J Mol Biol. 2008 Apr 11;377(5):1488-97. doi: 10.1016/j.jmb.2008.01.089. Epub 2008 Feb 9.

PMID:
18329042
49.

Crystallization and preliminary crystallographic studies of human kallikrein 7, a serine protease of the multigene kallikrein family.

Fernández IS, Ständker L, Forssmann WG, Giménez-Gallego G, Romero A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt 8):669-72. Epub 2007 Jul 7.

50.

Nutritional assessment of marginally nourished surgical patients.

Fernandez IS, Kurpad AV, Kilpadi AB, Shetty PS.

Natl Med J India. 1993 Nov-Dec;6(6):253-6.

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