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Items: 1 to 50 of 51

1.

A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase.

Giancotti G, Rigo I, Pasqualetto G, Young MT, Neyts J, Rocha-Pereira J, Brancale A, Ferla S, Bassetto M.

Sci Rep. 2019 Dec 5;9(1):18413. doi: 10.1038/s41598-019-54903-7.

2.

Corrigendum to "Advances in laparoscopic surgery for cervical cancer" [Crit. Rev. Oncol. Hematol. 143 (August) (2019) 76-80].

Bogani G, Leone Roberti Maggiore U, Rossetti D, Ditto A, Martinelli F, Chiappa V, Ferla S, Indini A, Sabatucci I, Lorusso D, Raspagliesi F.

Crit Rev Oncol Hematol. 2020 Jan;145:102833. doi: 10.1016/j.critrevonc.2019.102833. Epub 2019 Nov 26. No abstract available.

PMID:
31783292
3.

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF.

PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov.

4.

Advances in laparoscopic surgery for cervical cancer.

Bogani G, Leone Roberti Maggiore U, Rossetti D, Ditto A, Martinelli F, Chiappa V, Ferla S, Indini A, Sabatucci I, Lorusso D, Raspagliesi F.

Crit Rev Oncol Hematol. 2019 Nov;143:76-80. doi: 10.1016/j.critrevonc.2019.07.021. Epub 2019 Aug 2. Review. Erratum in: Crit Rev Oncol Hematol. 2020 Jan;145:102833.

PMID:
31499276
5.

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.

Romagnoli R, Oliva P, Salvador MK, Camacho ME, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Grillo E, Bortolozzi R, Rruga F, Mariotto E, Viola G.

Eur J Med Chem. 2019 Nov 1;181:111577. doi: 10.1016/j.ejmech.2019.111577. Epub 2019 Aug 1.

PMID:
31400707
6.

Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91. doi: 10.1016/j.ijpddr.2019.07.001. Epub 2019 Jul 2. No abstract available.

7.

A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer.

Pertusati F, Ferla S, Bassetto M, Brancale A, Khandil S, Westwell AD, McGuigan C.

Eur J Med Chem. 2019 Oct 15;180:1-14. doi: 10.1016/j.ejmech.2019.07.001. Epub 2019 Jul 3.

PMID:
31288149
8.

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.

Płaszczyca A, Scaturro P, Neufeldt CJ, Cortese M, Cerikan B, Ferla S, Brancale A, Pichlmair A, Bartenschlager R.

PLoS Pathog. 2019 May 9;15(5):e1007736. doi: 10.1371/journal.ppat.1007736. eCollection 2019 May.

9.

Treatment modalities for recurrent high-grade vaginal intraepithelial neoplasia.

Bogani G, Ditto A, Ferla S, Paolini B, Lombardo C, Lorusso D, Raspagliesi F.

J Gynecol Oncol. 2019 Mar;30(2):e20. doi: 10.3802/jgo.2019.30.e20. Epub 2018 Nov 8.

10.

Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.

Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Schiaffino Ortega S, Chayah M, Kimatrai Salvador M, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Mattiuzzo E, Viola G.

J Med Chem. 2019 Feb 14;62(3):1274-1290. doi: 10.1021/acs.jmedchem.8b01391. Epub 2019 Jan 18.

PMID:
30633509
11.

Nomogram-based prediction of cervical dysplasia persistence/recurrence.

Bogani G, Tagliabue E, Ferla S, Martinelli F, Ditto A, Chiappa V, Leone Roberti Maggiore U, Taverna F, Lombardo C, Lorusso D, Raspagliesi F.

Eur J Cancer Prev. 2019 Sep;28(5):435-440. doi: 10.1097/CEJ.0000000000000475.

PMID:
30489353
12.

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):559-570. doi: 10.1016/j.ijpddr.2018.10.005. Epub 2018 Nov 13. Erratum in: Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91.

13.

Artificial intelligence weights the importance of factors predicting complete cytoreduction at secondary cytoreductive surgery for recurrent ovarian cancer.

Bogani G, Rossetti D, Ditto A, Martinelli F, Chiappa V, Mosca L, Leone Roberti Maggiore U, Ferla S, Lorusso D, Raspagliesi F.

J Gynecol Oncol. 2018 Sep;29(5):e66. doi: 10.3802/jgo.2018.29.e66. Epub 2018 Apr 23.

14.

3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.

Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G.

Bioorg Chem. 2018 Oct;80:361-374. doi: 10.1016/j.bioorg.2018.06.037. Epub 2018 Jun 30.

PMID:
29986184
15.

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP).

Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM.

Antiviral Res. 2018 Aug;156:55-63. doi: 10.1016/j.antiviral.2018.05.010. Epub 2018 May 26.

16.

In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase.

Ferla S, Netzler NE, Ferla S, Veronese S, Tuipulotu DE, Guccione S, Brancale A, White PA, Bassetto M.

Sci Rep. 2018 Mar 7;8(1):4129. doi: 10.1038/s41598-018-22303-y.

17.

Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides.

Slusarczyk M, Ferla S, Brancale A, McGuigan C.

Bioorg Med Chem. 2018 Feb 1;26(3):551-565. doi: 10.1016/j.bmc.2017.11.037. Epub 2017 Dec 2.

PMID:
29277307
18.

2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.

Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.

Eur J Med Chem. 2018 Jan 1;143:683-698. doi: 10.1016/j.ejmech.2017.11.096.

19.

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

Lauder SN, Allen-Redpath K, Slatter DA, Aldrovandi M, O'Connor A, Farewell D, Percy CL, Molhoek JE, Rannikko S, Tyrrell VJ, Ferla S, Milne GL, Poole AW, Thomas CP, Obaji S, Taylor PR, Jones SA, de Groot PG, Urbanus RT, Hörkkö S, Uderhardt S, Ackermann J, Vince Jenkins P, Brancale A, Krönke G, Collins PW, O'Donnell VB.

Sci Signal. 2017 Nov 28;10(507). pii: eaan2787. doi: 10.1126/scisignal.aan2787.

20.

Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization.

Ferrara M, Sessa G, Fiore M, Bernard F, Asteriti IA, Cundari E, Colotti G, Ferla S, Desideri M, Buglioni S, Trisciuoglio D, Del Bufalo D, Brancale A, Degrassi F.

Oncogene. 2018 Jan 11;37(2):231-240. doi: 10.1038/onc.2017.320. Epub 2017 Sep 18.

21.

Broad-spectrum non-nucleoside inhibitors for caliciviruses.

Netzler NE, Enosi Tuipulotu D, Eltahla AA, Lun JH, Ferla S, Brancale A, Urakova N, Frese M, Strive T, Mackenzie JM, White PA.

Antiviral Res. 2017 Oct;146:65-75. doi: 10.1016/j.antiviral.2017.07.014. Epub 2017 Jul 27.

PMID:
28757394
22.

Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents.

Bassetto M, Ferla S, Giancotti G, Pertusati F, Westwell AD, Brancale A, McGuigan C.

Medchemcomm. 2017 May 26;8(7):1414-1420. doi: 10.1039/c7md00164a. eCollection 2017 Jul 1.

23.

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Salvador MK, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Porcù E, Basso G, Viola G.

Sci Rep. 2017 Apr 13;7:46356. doi: 10.1038/srep46356.

24.

Therapeutically targeting guanylate cyclase-C: computational modeling of plecanatide, a uroguanylin analog.

Brancale A, Shailubhai K, Ferla S, Ricci A, Bassetto M, Jacob GS.

Pharmacol Res Perspect. 2017 Mar 12;5(2):e00295. doi: 10.1002/prp2.295. eCollection 2017 Apr.

25.

Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication.

Scuotto M, Abdelnabi R, Collarile S, Schiraldi C, Delang L, Massa A, Ferla S, Brancale A, Leyssen P, Neyts J, Filosa R.

Bioorg Med Chem. 2017 Jan 1;25(1):327-337. doi: 10.1016/j.bmc.2016.10.037. Epub 2016 Oct 31.

PMID:
27856239
26.

Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents.

Bassetto M, Ferla S, Leyssen P, Neyts J, Yerukhimovich MM, Frick DN, O'Donnell R, Brancale A.

Antivir Chem Chemother. 2015 Dec;24(5-6):155-160. doi: 10.1177/2040206616676353. Epub 2016 Nov 4.

27.

Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety.

Ferla S, Bassetto M, Pertusati F, Kandil S, Westwell AD, Brancale A, McGuigan C.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3636-40. doi: 10.1016/j.bmcl.2016.06.001. Epub 2016 Jun 2.

PMID:
27301368
28.

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Tabrizi MA, Lopez-Cara LC, Ferla S, Brancale A, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Basso G, Viola G.

Sci Rep. 2016 May 24;6:26602. doi: 10.1038/srep26602.

29.

Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer.

Bassetto M, Ferla S, Pertusati F, Kandil S, Westwell AD, Brancale A, McGuigan C.

Eur J Med Chem. 2016 Aug 8;118:230-43. doi: 10.1016/j.ejmech.2016.04.052. Epub 2016 Apr 22.

30.

Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization.

Grande F, Parisi OI, Mordocco RA, Rocca C, Puoci F, Scrivano L, Quintieri AM, Cantafio P, Ferla S, Brancale A, Saturnino C, Cerra MC, Sinicropi MS, Angelone T.

Eur J Pharm Sci. 2016 Jan 20;82:161-70. doi: 10.1016/j.ejps.2015.11.021. Epub 2015 Dec 2.

PMID:
26631584
31.

Polyfluorinated groups in medicinal chemistry.

Bassetto M, Ferla S, Pertusati F.

Future Med Chem. 2015;7(4):527-46. doi: 10.4155/fmc.15.5. Review.

PMID:
25875877
32.

Impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional hand hygiene approach in 3 cities in Brazil.

Medeiros EA, Grinberg G, Rosenthal VD, Bicudo Angelieri D, Buchner Ferreira I, Bauer Cechinel R, Zanandrea BB, Rohnkohl C, Regalin M, Spessatto JL, Scopel Pasini R, Ferla S.

Am J Infect Control. 2015 Jan;43(1):10-5. doi: 10.1016/j.ajic.2014.10.001.

PMID:
25564118
33.

Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation.

Ferla S, Gomaa MS, Brancale A, Zhu J, Ochalek JT, DeLuca HF, Simons C.

Eur J Med Chem. 2014 Nov 24;87:39-51. doi: 10.1016/j.ejmech.2014.09.035. Epub 2014 Sep 16.

PMID:
25240094
34.

Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation.

Ferla S, Aboraia AS, Brancale A, Pepper CJ, Zhu J, Ochalek JT, DeLuca HF, Simons C.

J Med Chem. 2014 Sep 25;57(18):7702-15. doi: 10.1021/jm5009314. Epub 2014 Sep 8.

PMID:
25148392
35.

Successful subthalamic stimulation in genetic Parkinson's disease caused by duplication of the α-synuclein gene.

Antonini A, Pilleri M, Padoan A, Landi A, Ferla S, Biundo R, D'Avella D.

J Neurol. 2012 Jan;259(1):165-7. doi: 10.1007/s00415-011-6162-2. Epub 2011 Jul 15.

PMID:
21761143
36.

PTP1B inhibitors: synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold.

Holmes CP, Li X, Pan Y, Xu C, Bhandari A, Moody CM, Miguel JA, Ferla SW, De Francisco MN, Frederick BT, Zhou S, Macher N, Jang L, Irvine JD, Grove JR.

Bioorg Med Chem Lett. 2008 Apr 15;18(8):2719-24. doi: 10.1016/j.bmcl.2008.03.007. Epub 2008 Mar 6.

PMID:
18372175
37.

Biomechanical evaluation of scapular girdle in patients with chronic arm lymphedema.

Balzarini A, Lualdi P, Lucarini C, Ferla S, Galli M, Crivellini M, DeConno F.

Lymphology. 2006 Sep;39(3):132-40.

PMID:
17036634
38.

Discovery and structure-activity relationships of novel sulfonamides as potent PTP1B inhibitors.

Holmes CP, Li X, Pan Y, Xu C, Bhandari A, Moody CM, Miguel JA, Ferla SW, De Francisco MN, Frederick BT, Zhou S, Macher N, Jang L, Irvine JD, Grove JR.

Bioorg Med Chem Lett. 2005 Oct 1;15(19):4336-41.

PMID:
16046123
39.

On-line sample preparation for high throughput reversed-phase LC/MS analysis of combinatorial chemistry libraries.

Tang L, Fitch WL, Smith P, Tumelty D, Cao K, Ferla SW.

Comb Chem High Throughput Screen. 2001 May;4(3):287-93.

PMID:
11375743
40.

Structure-based design of six novel classes of nonpeptide antagonists of the bradykinin B2 receptor.

Artis DR, Brotherton-Pleiss C, Pease JH, Lin CJ, Ferla SW, Newman SR, Bhakta S, Ostrelich H, Jarnagin K.

Bioorg Med Chem Lett. 2000 Nov 6;10(21):2421-5.

PMID:
11078192
41.

Solitary plasmacytoma: a case report.

Pasqui L, Ferla S, Giordano R, Garbin O.

Ital J Neurol Sci. 1992 May;13(4):351-3.

PMID:
1601634
42.

Growth factor (M-CSF) and antigenic properties of macrophages in meningioma.

Giometto B, Bozza F, Gallo P, Pagni S, Argentiero V, Ferla S, Mingrino S, Tavolato B.

J Neurooncol. 1992 May;13(1):25-33.

PMID:
1377230
43.

[Analgesic effect of Sandostatin (SMS 201-995) in acromegaly headache].

Sicolo N, Martini C, Ferla S, Roggenkamp J, Vettor R, De Palo C, Federspil G.

Minerva Endocrinol. 1990 Jan-Mar;15(1):37-42. Italian.

PMID:
2274013
44.

Pineal germinoma: diagnosis, treatment and tumor response.

Ferla S, Spartà S, Giordano R, Zorat PL, Marin G, Meneghetti G.

Ital J Neurol Sci. 1987 Jun;8(3):267-70.

PMID:
3623879
45.

Therapeutic effect of lisuride in advanced Parkinson's disease.

Meneghetti G, Bracco F, Giometto B, Ferla S, Schergna E.

Eur Neurol. 1986;25(1):74-80.

PMID:
3510126
46.

Effect of lymphocytapheresis plus cyclophosphamide on the course of a chronic progressive form of multiple sclerosis.

Ferla S, Meneghetti G, Spartà S, Belloni M, Ongaro G.

Ital J Neurol Sci. 1985 Sep;6(3):283-6.

PMID:
4066266
47.

[Neoplasms of the brain stem: clinico-pathologic correlations].

Giordano R, Ferla S, Danieli D, Tavolato B.

Riv Neurol. 1984 May-Jun;54(3):179-91. Italian.

PMID:
6474065
48.

Wernicke-Korsakoff syndrome after subtotal gastrectomy.

Ferla S, Giometto B, Meneghetti G, Schergna E.

Ital J Neurol Sci. 1983 Jun;4(2):225-7.

PMID:
6618863
49.

Alzheimer's disease and senile brains: an immunofluorescence study.

Licandro A, Ferla S, Tavolato B.

Riv Patol Nerv Ment. 1983 Mar-Apr;104(2):75-87.

PMID:
6387867
50.

[The importance of plastic surgery in injuries of the facial bones].

La Ferla S, Meyer R.

Minerva Otorinolaringol. 1967 Mar-Apr;17(3):40-50. Italian. No abstract available.

PMID:
4885417

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