Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 198


Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells.

Buick JK, Williams A, Gagné R, Swartz CD, Recio L, Ferguson SS, Yauk CL.

Genes Environ. 2020 Feb 4;42:5. doi: 10.1186/s41021-019-0139-2. eCollection 2020.


mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson's Disease.

Farmer K, Abd-Elrahman KS, Derksen A, Rowe EM, Thompson AM, Rudyk CA, Prowse NA, Dwyer Z, Bureau SC, Fortin T, Ferguson SSG, Hayley S.

Mol Neurobiol. 2020 Mar;57(3):1418-1431. doi: 10.1007/s12035-019-01818-z. Epub 2019 Nov 21.


Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data.

Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV.

Toxicol Sci. 2019 Dec 1;172(2):316-329. doi: 10.1093/toxsci/kfz189.


Structural determinants governing β-arrestin2 interaction with PDZ proteins and recruitment to CRFR1.

Gupta S, Abd-Elrahman KS, Albaker A, Dunn HA, Ferguson SSG.

Cell Signal. 2019 Nov;63:109361. doi: 10.1016/j.cellsig.2019.109361. Epub 2019 Jul 22.


Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis.

Ramaiahgari SC, Ferguson SS.

Methods Mol Biol. 2019;1981:313-323. doi: 10.1007/978-1-4939-9420-5_20.


Super-Resolution Imaging of G Protein-Coupled Receptors Using Ground State Depletion Microscopy.

Caetano Crowley FA, Heit B, Ferguson SSG.

Methods Mol Biol. 2019;1947:323-336. doi: 10.1007/978-1-4939-9121-1_18.


Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington's pathology in zQ175 mice.

Abd-Elrahman KS, Ferguson SSG.

Mol Brain. 2019 Apr 8;12(1):35. doi: 10.1186/s13041-019-0456-1.


Methods to Investigate the Roles of β-Arrestin-Dependent RalGDS Activation in GPCR-Stimulated Membrane Blebbing.

Ferguson SSG.

Methods Mol Biol. 2019;1957:169-175. doi: 10.1007/978-1-4939-9158-7_11.


Information Needs for Treatment Decision-making of Hematopoietic Cell Transplant Patients 65 Years or Older and Caregivers.

Foster J, Moore H, Preussler JM, Burns LJ, Umar JH, Glotzbecker B, Johnson S, MacDougall H, Mau LW, Murphy EA, Ustun C, Ferguson SS, Denzen E.

J Cancer Educ. 2019 Mar 15. doi: 10.1007/s13187-019-01506-5. [Epub ahead of print]


The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling.

Ramaiahgari SC, Auerbach SS, Saddler TO, Rice JR, Dunlap PE, Sipes NS, DeVito MJ, Shah RR, Bushel PR, Merrick BA, Paules RS, Ferguson SS.

Toxicol Sci. 2019 Jun 1;169(2):553-566. doi: 10.1093/toxsci/kfz065.


Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation.

Areal LB, Hamilton A, Martins-Silva C, Pires RGW, Ferguson SSG.

Mol Brain. 2019 Feb 25;12(1):15. doi: 10.1186/s13041-019-0434-7.


Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop.

Ellison CA, Blackburn KL, Carmichael PL, Clewell HJ 3rd, Cronin MTD, Desprez B, Escher SE, Ferguson SS, Grégoire S, Hewitt NJ, Hollnagel HM, Klaric M, Patel A, Salhi S, Schepky A, Schmitt BG, Wambaugh JF, Worth A.

Regul Toxicol Pharmacol. 2019 Apr;103:63-72. doi: 10.1016/j.yrtph.2019.01.016. Epub 2019 Jan 15. Review.


Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber.

Perkins AN, Inayat-Hussain SH, Deziel NC, Johnson CH, Ferguson SS, Garcia-Milian R, Thompson DC, Vasiliou V.

Environ Res. 2019 Feb;169:163-172. doi: 10.1016/j.envres.2018.10.018. Epub 2018 Oct 24.


Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals.

Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY, Hsieh JH, Wetmore BA, Ferguson SS, DeVito MJ, Sprankle CS, Kleinstreuer NC.

Environ Health Perspect. 2018 Sep;126(9):97001. doi: 10.1289/EHP1655.


Access to Linguistically Appropriate Information for Blood and Marrow Transplant Patients: Results from Transplant Center Staff Survey.

Idossa L, Mau LW, Ferguson SS, Denzen E, Murphy E, Moore H.

J Cancer Educ. 2019 Oct;34(5):1031-1037. doi: 10.1007/s13187-018-1407-8.


Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-Like Receptor Pathway.

Holterman CE, Boisvert NC, Thibodeau JF, Kamto E, Novakovic M, Abd-Elrahman KS, Ferguson SSG, Kennedy CRJ.

Antioxid Redox Signal. 2019 May 20;30(15):1817-1830. doi: 10.1089/ars.2017.7402. Epub 2018 Sep 8.


GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation.

Tutunea-Fatan E, Abd-Elrahman KS, Thibodeau JF, Holterman CE, Holleran BJ, Leduc R, Kennedy CRJ, Gros R, Ferguson SSG.

Sci Rep. 2018 Jul 30;8(1):11415. doi: 10.1038/s41598-018-29876-8.


How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract.

Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV.

Food Chem Toxicol. 2018 Aug;118:328-339. doi: 10.1016/j.fct.2018.05.013. Epub 2018 May 9.


Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer's disease mouse models.

Abd-Elrahman KS, Hamilton A, Vasefi M, Ferguson SSG.

Mol Brain. 2018 Apr 10;11(1):19. doi: 10.1186/s13041-018-0364-9.


MAGI proteins can differentially regulate the signaling pathways of 5-HT2AR by enhancing receptor trafficking and PLC recruitment.

Hammad MM, Dunn HA, Ferguson SSG.

Cell Signal. 2018 Jul;47:109-121. doi: 10.1016/j.cellsig.2018.03.016. Epub 2018 Apr 3.


mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington's disease.

Abd-Elrahman KS, Hamilton A, Hutchinson SR, Liu F, Russell RC, Ferguson SSG.

Sci Signal. 2017 Dec 19;10(510). pii: eaan6387. doi: 10.1126/scisignal.aan6387.


In vitro to in vivo extrapolation for high throughput prioritization and decision making.

Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC.

Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Review.


Tip-enhanced Raman spectroscopy of amyloid β at neuronal spines.

Tabatabaei M, Caetano FA, Pashee F, Ferguson SSG, Lagugné-Labarthet F.

Analyst. 2017 Nov 20;142(23):4415-4421. doi: 10.1039/c7an00744b.


Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Ramaiahgari SC, Waidyanatha S, Dixon D, DeVito MJ, Paules RS, Ferguson SS.

Toxicol Sci. 2017 Nov 1;160(1):189-190. doi: 10.1093/toxsci/kfx194. No abstract available.


Role of Dynein Axonemal Heavy Chain 6 Gene Expression as a Possible Biomarker for Huntington's Disease: a Translational Study.

Areal LB, Pereira LP, Ribeiro FM, Olmo IG, Muniz MR, do Carmo Rodrigues M, Costa PF, Martins-Silva C, Ferguson SSG, Guimarães DAM, Pires RGW.

J Mol Neurosci. 2017 Dec;63(3-4):342-348. doi: 10.1007/s12031-017-0984-z. Epub 2017 Oct 10.


An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library.

Sipes NS, Wambaugh JF, Pearce R, Auerbach SS, Wetmore BA, Hsieh JH, Shapiro AJ, Svoboda D, DeVito MJ, Ferguson SS.

Environ Sci Technol. 2017 Sep 19;51(18):10786-10796. doi: 10.1021/acs.est.7b00650. Epub 2017 Sep 6.


From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Ramaiahgari SC, Waidyanatha S, Dixon D, DeVito MJ, Paules RS, Ferguson SS.

Toxicol Sci. 2017 Sep 1;159(1):124-136. doi: 10.1093/toxsci/kfx122. Erratum in: Toxicol Sci. 2017 Nov 1;160(1):189-190.


MAGI Proteins Regulate the Trafficking and Signaling of Corticotropin-Releasing Factor Receptor 1 via a Compensatory Mechanism.

Hammad MM, Dunn HA, Ferguson SSG.

J Mol Signal. 2016 Nov 28;11:5. doi: 10.5334/1750-2187-11-5.


Metabotropic glutamate receptors and neurodegenerative diseases.

Ribeiro FM, Vieira LB, Pires RG, Olmo RP, Ferguson SS.

Pharmacol Res. 2017 Jan;115:179-191. doi: 10.1016/j.phrs.2016.11.013. Epub 2016 Nov 19. Review.


Systems biology for organotypic cell cultures.

Grego S, Dougherty ER, Alexander FJ, Auerbach SS, Berridge BR, Bittner ML, Casey W, Cooley PC, Dash A, Ferguson SS, Fennell TR, Hawkins BT, Hickey AJ, Kleensang A, Liebman MNJ, Martin F, Maull EA, Paragas J, Qiao GG, Ramaiahgari S, Sumner SJ, Yoon M.

ALTEX. 2017;34(2):301-310. doi: 10.14573/altex.1608221. Epub 2016 Nov 14.


GRK2 targeted knock-down results in spontaneous hypertension, and altered vascular GPCR signaling.

Tutunea-Fatan E, Caetano FA, Gros R, Ferguson SS.

J Biol Chem. 2016 Sep 23;291(39):20822. doi: 10.1074/jbc.A114.615658. No abstract available.


Orchestrated activation of mGluR5 and CB1 promotes neuroprotection.

Batista EM, Doria JG, Ferreira-Vieira TH, Alves-Silva J, Ferguson SS, Moreira FA, Ribeiro FM.

Mol Brain. 2016 Aug 20;9(1):80. doi: 10.1186/s13041-016-0259-6.


Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity.

Di Sebastiano AR, Fahim S, Dunn HA, Walther C, Ribeiro FM, Cregan SP, Angers S, Schmid S, Ferguson SS.

J Biol Chem. 2016 Aug 19;291(34):17602-15. doi: 10.1074/jbc.M116.722355. Epub 2016 Jun 29.


Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures.

Jackson JP, Li L, Chamberlain ED, Wang H, Ferguson SS.

Drug Metab Dispos. 2016 Sep;44(9):1463-79. doi: 10.1124/dmd.116.069831. Epub 2016 Jun 23.


Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury.

Thibodeau JF, Holterman CE, He Y, Carter A, Cron GO, Boisvert NC, Abd-Elrahman KS, Hsu KJ, Ferguson SS, Kennedy CR.

Antioxid Redox Signal. 2016 Oct 20;25(12):642-656. Epub 2016 Aug 5.


Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.

Hamilton A, Vasefi M, Vander Tuin C, McQuaid RJ, Anisman H, Ferguson SS.

Cell Rep. 2016 May 31;15(9):1859-65. doi: 10.1016/j.celrep.2016.04.077. Epub 2016 May 19.


Tip-enhanced Raman spectroscopy: plasmid-free vs. plasmid-embedded DNA.

Pashaee F, Tabatabaei M, Caetano FA, Ferguson SS, Lagugné-Labarthet F.

Analyst. 2016 Jun 7;141(11):3251-8. doi: 10.1039/c6an00350h. Epub 2016 Apr 12.


PSD-95 regulates CRFR1 localization, trafficking and β-arrestin2 recruitment.

Dunn HA, Chahal HS, Caetano FA, Holmes KD, Yuan GY, Parikh R, Heit B, Ferguson SSG.

Cell Signal. 2016 May;28(5):531-540. doi: 10.1016/j.cellsig.2016.02.013. Epub 2016 Feb 17.


Controlled positioning of analytes and cells on a plasmonic platform for glycan sensing using surface enhanced Raman spectroscopy.

Tabatabaei M, Wallace GQ, Caetano FA, Gillies ER, Ferguson SSG, Lagugné-Labarthet F.

Chem Sci. 2016 Jan 1;7(1):575-582. doi: 10.1039/c5sc03332b. Epub 2015 Oct 16.


MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures.

Caetano FA, Dirk BS, Tam JH, Cavanagh PC, Goiko M, Ferguson SS, Pasternak SH, Dikeakos JD, de Bruyn JR, Heit B.

PLoS Comput Biol. 2015 Dec 11;11(12):e1004634. doi: 10.1371/journal.pcbi.1004634. eCollection 2015 Dec.


Patient housing barriers to hematopoietic cell transplantation: results from a mixed-methods study of transplant center social workers.

Preussler JM, Mau LW, Majhail NS, Bevans M, Clancy E, Messner C, Parran L, Pederson KA, Ferguson SS, Walters K, Murphy EA, Denzen EM.

Support Care Cancer. 2016 Mar;24(3):1167-74. doi: 10.1007/s00520-015-2872-9. Epub 2015 Aug 15.


Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.

Wetmore BA, Wambaugh JF, Allen B, Ferguson SS, Sochaski MA, Setzer RW, Houck KA, Strope CL, Cantwell K, Judson RS, LeCluyse E, Clewell HJ, Thomas RS, Andersen ME.

Toxicol Sci. 2015 Nov;148(1):121-36. doi: 10.1093/toxsci/kfv171. Epub 2015 Aug 6.


Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1.

Hammad MM, Dunn HA, Walther C, Ferguson SS.

Cell Signal. 2015 Oct;27(10):2120-30. doi: 10.1016/j.cellsig.2015.06.004. Epub 2015 Jun 23.


Suppression of piriform cortex activity in rat by corticotropin-releasing factor 1 and serotonin 2A/C receptors.

Narla C, Dunn HA, Ferguson SS, Poulter MO.

Front Cell Neurosci. 2015 May 28;9:200. doi: 10.3389/fncel.2015.00200. eCollection 2015.


Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.

Walther C, Ferguson SS.

Mol Endocrinol. 2015 Jun;29(6):814-30. doi: 10.1210/me.2015-1091. Epub 2015 May 5. Review.


Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes.

Hamilton A, Zamponi GW, Ferguson SS.

Mol Brain. 2015 Mar 24;8:18. doi: 10.1186/s13041-015-0107-0. Review.


The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates.

Guimaraes IM, Carvalho TG, Ferguson SS, Pereira GS, Ribeiro FM.

Mol Brain. 2015 Apr 10;8:24. doi: 10.1186/s13041-015-0113-2.


Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid.

Raka F, Di Sebastiano AR, Kulhawy SC, Ribeiro FM, Godin CM, Caetano FA, Angers S, Ferguson SS.

Mol Brain. 2015 Mar 26;8:21. doi: 10.1186/s13041-015-0111-4.


PDZ Protein Regulation of G Protein-Coupled Receptor Trafficking and Signaling Pathways.

Dunn HA, Ferguson SS.

Mol Pharmacol. 2015 Oct;88(4):624-39. doi: 10.1124/mol.115.098509. Epub 2015 Mar 25. Review.


PDZK1/NHERF3 differentially regulates corticotropin-releasing factor receptor 1 and serotonin 2A receptor signaling and endocytosis.

Walther C, Caetano FA, Dunn HA, Ferguson SS.

Cell Signal. 2015 Mar;27(3):519-31. doi: 10.1016/j.cellsig.2014.12.019. Epub 2015 Jan 3.


Supplemental Content

Loading ...
Support Center