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Items: 10

1.

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

Barrett SD, Bridges AJ, Dudley DT, Saltiel AR, Fergus JH, Flamme CM, Delaney AM, Kaufman M, LePage S, Leopold WR, Przybranowski SA, Sebolt-Leopold J, Van Becelaere K, Doherty AM, Kennedy RM, Marston D, Howard WA Jr, Smith Y, Warmus JS, Tecle H.

Bioorg Med Chem Lett. 2008 Dec 15;18(24):6501-4. doi: 10.1016/j.bmcl.2008.10.054. Epub 2008 Oct 15.

PMID:
18952427
2.

Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand.

Plummer MS, Holland DR, Shahripour A, Lunney EA, Fergus JH, Marks JS, McConnell P, Mueller WT, Sawyer TK.

J Med Chem. 1997 Nov 7;40(23):3719-25.

PMID:
9371236
3.

Design of peptidomimetic ligands for the pp60src SH2 domain.

Plummer MS, Lunney EA, Para KS, Shahripour A, Stankovic CJ, Humblet C, Fergus JH, Marks JS, Herrera R, Hubbell S, Saltiel A, Sawyer TK.

Bioorg Med Chem. 1997 Jan;5(1):41-7. No abstract available.

PMID:
9043656
4.

Hydrophobic D-amino acids in the design of peptide ligands for the pp60src SH2 domain.

Plummer MS, Lunney EA, Para KS, Prasad JV, Shahripour A, Singh J, Stankovic CJ, Humblet C, Fergus JH, Marks JS, Sawyer TK.

Drug Des Discov. 1996 Apr;13(3-4):75-81.

PMID:
8874045
5.

PD 90780, a non peptide inhibitor of nerve growth factor's binding to the P75 NGF receptor.

Spiegel K, Agrafiotis D, Caprathe B, Davis RE, Dickerson MR, Fergus JH, Hepburn TW, Marks JS, Van Dorf M, Wieland DM, et al.

Biochem Biophys Res Commun. 1995 Dec 14;217(2):488-94.

PMID:
7503726
6.

Structure-activity relationships for enhancement of adenosine A1 receptor binding by 2-amino-3-benzoylthiophenes.

Bruns RF, Fergus JH, Coughenour LL, Courtland GG, Pugsley TA, Dodd JH, Tinney FJ.

Mol Pharmacol. 1990 Dec;38(6):950-8.

PMID:
2250667
7.
8.

Solubilities of adenosine antagonists determined by radioreceptor assay.

Bruns RF, Fergus JH.

J Pharm Pharmacol. 1989 Sep;41(9):590-4.

PMID:
2573701
9.

PD 115,199: an antagonist ligand for adenosine A2 receptors.

Bruns RF, Fergus JH, Badger EW, Bristol JA, Santay LA, Hays SJ.

Naunyn Schmiedebergs Arch Pharmacol. 1987 Jan;335(1):64-9.

PMID:
3574493
10.

Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes.

Bruns RF, Fergus JH, Badger EW, Bristol JA, Santay LA, Hartman JD, Hays SJ, Huang CC.

Naunyn Schmiedebergs Arch Pharmacol. 1987 Jan;335(1):59-63.

PMID:
3574492

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