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Items: 1 to 50 of 80


Clinical characterization of colitis arising from anti-PD-1 based therapy.

Wang DY, Mooradian MJ, Kim D, Shah NJ, Fenton SE, Conry RM, Mehta R, Silk AW, Zhou A, Compton ML, Al-Rohil RN, Lee S, Voorhees AL, Ha L, McKee S, Norrell JT, Mehnert J, Puzanov I, Sosman JA, Chandra S, Gibney GT, Rapisuwon S, Eroglu Z, Sullivan R, Johnson DB.

Oncoimmunology. 2018 Oct 31;8(1):e1524695. doi: 10.1080/2162402X.2018.1524695. eCollection 2019.


Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells.

Chappell VA, Janesick A, Blumberg B, Fenton SE.

Toxicol Sci. 2018 Dec 1;166(2):332-344. doi: 10.1093/toxsci/kfy209.


Associations between longitudinal serum perfluoroalkyl substance (PFAS) levels and measures of thyroid hormone, kidney function, and body mass index in the Fernald Community Cohort.

Blake BE, Pinney SM, Hines EP, Fenton SE, Ferguson KK.

Environ Pollut. 2018 Nov;242(Pt A):894-904. doi: 10.1016/j.envpol.2018.07.042. Epub 2018 Jul 17.


Evaluation of Prenatal Exposure to Bisphenol Analogues on Development and Long-Term Health of the Mammary Gland in Female Mice.

Tucker DK, Hayes Bouknight S, Brar SS, Kissling GE, Fenton SE.

Environ Health Perspect. 2018 Aug 10;126(8):087003. doi: 10.1289/EHP3189. eCollection 2018 Aug.


Animal models of endocrine disruption.

Patisaul HB, Fenton SE, Aylor D.

Best Pract Res Clin Endocrinol Metab. 2018 Jun;32(3):283-297. doi: 10.1016/j.beem.2018.03.011. Epub 2018 Apr 6. Review.


Sectioning Mammary Gland Whole Mounts for Lesion Identification.

Tucker DK, Foley JF, Bouknight SA, Fenton SE.

J Vis Exp. 2017 Jul 24;(125). doi: 10.3791/55796.


Quantifying Branching Density in Rat Mammary Gland Whole-mounts Using the Sholl Analysis Method.

Stanko JP, Fenton SE.

J Vis Exp. 2017 Jul 12;(125). doi: 10.3791/55789.


Emerging growth factor receptor antagonists for the treatment of advanced melanoma.

Fenton SE, Sosman JA, Chandra S.

Expert Opin Emerg Drugs. 2017 Jun;22(2):165-174. doi: 10.1080/14728214.2017.1336537. Review.


Effects of perfluorinated chemicals on thyroid function, markers of ovarian reserve, and natural fertility.

Crawford NM, Fenton SE, Strynar M, Hines EP, Pritchard DA, Steiner AZ.

Reprod Toxicol. 2017 Apr;69:53-59. doi: 10.1016/j.reprotox.2017.01.006. Epub 2017 Jan 19.


Gestational exposure to perfluorooctanoic acid (PFOA): Alterations in motor related behaviors.

Goulding DR, White SS, McBride SJ, Fenton SE, Harry GJ.

Neurotoxicology. 2017 Jan;58:110-119. doi: 10.1016/j.neuro.2016.11.008. Epub 2016 Nov 22.


Mammary Gland Evaluation in Juvenile Toxicity Studies: Temporal Developmental Patterns in the Male and Female Harlan Sprague-Dawley Rat.

Filgo AJ, Foley JF, Puvanesarajah S, Borde AR, Midkiff BR, Reed CE, Chappell VA, Alexander LB, Borde PR, Troester MA, Bouknight SA, Fenton SE.

Toxicol Pathol. 2016 Oct;44(7):1034-58. doi: 10.1177/0192623316663864. Epub 2016 Sep 9.


Preparation of High-quality Hematoxylin and Eosin-stained Sections from Rodent Mammary Gland Whole Mounts for Histopathologic Review.

Tucker DK, Foley JF, Hayes-Bouknight SA, Fenton SE.

Toxicol Pathol. 2016 Oct;44(7):1059-64. doi: 10.1177/0192623316660769. Epub 2016 Jul 29.


Polybrominated Diphenyl Ethers in Human Milk and Serum from the U.S. EPA MAMA Study: Modeled Predictions of Infant Exposure and Considerations for Risk Assessment.

Marchitti SA, Fenton SE, Mendola P, Kenneke JF, Hines EP.

Environ Health Perspect. 2017 Apr;125(4):706-713. doi: 10.1289/EHP332. Epub 2016 Jul 12.


EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals.

Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, Toppari J, Zoeller RT.

Endocr Rev. 2015 Dec;36(6):E1-E150. doi: 10.1210/er.2015-1010. Epub 2015 Nov 6. Review.


Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals.

Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, Toppari J, Zoeller RT.

Endocr Rev. 2015 Dec;36(6):593-602. doi: 10.1210/er.2015-1093. Epub 2015 Sep 28. Review.


Timing of Environmental Exposures as a Critical Element in Breast Cancer Risk.

Fenton SE, Birnbaum LS.

J Clin Endocrinol Metab. 2015 Sep;100(9):3245-50. doi: 10.1210/jc.2015-2848. Epub 2015 Jul 27. Review.


Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation.

Schwarzman MR, Ackerman JM, Dairkee SH, Fenton SE, Johnson D, Navarro KM, Osborne G, Rudel RA, Solomon GM, Zeise L, Janssen S.

Environ Health Perspect. 2015 Dec;123(12):1255-64. doi: 10.1289/ehp.1408337. Epub 2015 Jun 2. Review.


A special issue dedicated to a complex tissue.

Fenton SE.

Reprod Toxicol. 2015 Jul;54:1-5. doi: 10.1016/j.reprotox.2015.05.004. Epub 2015 May 15. No abstract available.


Essential role of Orai1 store-operated calcium channels in lactation.

Davis FM, Janoshazi A, Janardhan KS, Steinckwich N, D'Agostin DM, Petranka JG, Desai PN, Roberts-Thomson SJ, Bird GS, Tucker DK, Fenton SE, Feske S, Monteith GR, Putney JW Jr.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5827-32. doi: 10.1073/pnas.1502264112. Epub 2015 Apr 20.


The mammary gland is a sensitive pubertal target in CD-1 and C57Bl/6 mice following perinatal perfluorooctanoic acid (PFOA) exposure.

Tucker DK, Macon MB, Strynar MJ, Dagnino S, Andersen E, Fenton SE.

Reprod Toxicol. 2015 Jul;54:26-36. doi: 10.1016/j.reprotox.2014.12.002. Epub 2014 Dec 12.


Application of Sholl analysis to quantify changes in growth and development in rat mammary gland whole mounts.

Stanko JP, Easterling MR, Fenton SE.

Reprod Toxicol. 2015 Jul;54:129-35. doi: 10.1016/j.reprotox.2014.11.004. Epub 2014 Nov 15.


Concentrations of environmental phenols and parabens in milk, urine and serum of lactating North Carolina women.

Hines EP, Mendola P, von Ehrenstein OS, Ye X, Calafat AM, Fenton SE.

Reprod Toxicol. 2015 Jul;54:120-8. doi: 10.1016/j.reprotox.2014.11.006. Epub 2014 Nov 22.


Perfluorooctanoic Acid (PFOA)-induced Liver Lesions in Two Strains of Mice Following Developmental Exposures: PPARα Is Not Required.

Filgo AJ, Quist EM, Hoenerhoff MJ, Brix AE, Kissling GE, Fenton SE.

Toxicol Pathol. 2015 Jun;43(4):558-68. doi: 10.1177/0192623314558463. Epub 2014 Nov 14.


Hepatic Mitochondrial Alteration in CD-1 Mice Associated with Prenatal Exposures to Low Doses of Perfluorooctanoic Acid (PFOA).

Quist EM, Filgo AJ, Cummings CA, Kissling GE, Hoenerhoff MJ, Fenton SE.

Toxicol Pathol. 2015 Jun;43(4):546-57. doi: 10.1177/0192623314551841. Epub 2014 Oct 16.


Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk.

Lehmann GM, Verner MA, Luukinen B, Henning C, Assimon SA, LaKind JS, McLanahan ED, Phillips LJ, Davis MH, Powers CM, Hines EP, Haddad S, Longnecker MP, Poulsen MT, Farrer DG, Marchitti SA, Tan YM, Swartout JC, Sagiv SK, Welsh C, Campbell JL Jr, Foster WG, Yang RS, Fenton SE, Tornero-Velez R, Francis BM, Barnett JB, El-Masri HA, Simmons JE.

Crit Rev Toxicol. 2014 Aug;44(7):600-17. doi: 10.3109/10408444.2014.926306. Review.


FYNagling divergent adhesive functions for Fyn in keratinocytes.

Fenton SE, Denning MF.

Exp Dermatol. 2015 Feb;24(2):81-5. doi: 10.1111/exd.12485. Epub 2014 Nov 11.


Targeting Fyn in Ras-transformed cells induces F-actin to promote adherens junction-mediated cell-cell adhesion.

Fenton SE, Hutchens KA, Denning MF.

Mol Carcinog. 2015 Oct;54(10):1181-93. doi: 10.1002/mc.22190. Epub 2014 Jun 29.


Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects.

Reed CE, Fenton SE.

Birth Defects Res C Embryo Today. 2013 Jun;99(2):134-46. doi: 10.1002/bdrc.21035. Review.


Endocrine disruptors and the breast: early life effects and later life disease.

Macon MB, Fenton SE.

J Mammary Gland Biol Neoplasia. 2013 Mar;18(1):43-61. doi: 10.1007/s10911-013-9275-7. Epub 2013 Feb 17. Review.


Researching chemicals in human milk can be conducted without discouraging breastfeeding.

Dórea JG, Fenton SE, LaKind JS, Berlin CM Jr.

Bosn J Basic Med Sci. 2012 May;12(2):137-8. No abstract available.


Histopathologic changes in the uterus, cervix and vagina of immature CD-1 mice exposed to low doses of perfluorooctanoic acid (PFOA) in a uterotrophic assay.

Dixon D, Reed CE, Moore AB, Gibbs-Flournoy EA, Hines EP, Wallace EA, Stanko JP, Lu Y, Jefferson WN, Newbold RR, Fenton SE.

Reprod Toxicol. 2012 Jul;33(4):506-12. doi: 10.1016/j.reprotox.2011.10.011. Epub 2011 Nov 28.


Perinatal environmental exposures affect mammary development, function, and cancer risk in adulthood.

Fenton SE, Reed C, Newbold RR.

Annu Rev Pharmacol Toxicol. 2012;52:455-79. doi: 10.1146/annurev-pharmtox-010611-134659. Epub 2011 Oct 19. Review.


Developmental toxicology: new directions workshop: refining testing strategies and study designs.

Brannen KC, Fenton SE, Hansen DK, Harrouk W, Kim JH, Shuey D.

Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):404-12. doi: 10.1002/bdrb.20326.


Environmental exposures and mammary gland development: state of the science, public health implications, and research recommendations.

Rudel RA, Fenton SE, Ackerman JM, Euling SY, Makris SL.

Environ Health Perspect. 2011 Aug;119(8):1053-61. doi: 10.1289/ehp.1002864. Epub 2011 Jun 22. Review.


Gestational and chronic low-dose PFOA exposures and mammary gland growth and differentiation in three generations of CD-1 mice.

White SS, Stanko JP, Kato K, Calafat AM, Hines EP, Fenton SE.

Environ Health Perspect. 2011 Aug;119(8):1070-6. doi: 10.1289/ehp.1002741. Epub 2011 Apr 18.


Prenatal perfluorooctanoic acid exposure in CD-1 mice: low-dose developmental effects and internal dosimetry.

Macon MB, Villanueva LR, Tatum-Gibbs K, Zehr RD, Strynar MJ, Stanko JP, White SS, Helfant L, Fenton SE.

Toxicol Sci. 2011 Jul;122(1):134-45. doi: 10.1093/toxsci/kfr076. Epub 2011 Apr 11.


Endocrine disrupting properties of perfluorooctanoic acid.

White SS, Fenton SE, Hines EP.

J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):16-26. doi: 10.1016/j.jsbmb.2011.03.011. Epub 2011 Mar 21. Review.


Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.

Stanko JP, Enoch RR, Rayner JL, Davis CC, Wolf DC, Malarkey DE, Fenton SE.

Reprod Toxicol. 2010 Dec;30(4):540-9. doi: 10.1016/j.reprotox.2010.07.006. Epub 2010 Aug 19. Erratum in: Reprod Toxicol. 2011 Jul;32(1):146-7.


Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors.

Wang T, Gavin HM, Arlt VM, Lawrence BP, Fenton SE, Medina D, Vorderstrasse BA.

Int J Cancer. 2011 Apr 1;128(7):1509-23. doi: 10.1002/ijc.25493. Epub 2010 Jun 2.


The mammary gland: a tissue sensitive to environmental exposures.

Fenton SE.

Rev Environ Health. 2009 Oct-Dec;24(4):319-25. No abstract available.


Developmental exposure to a commercial PBDE mixture, DE-71: neurobehavioral, hormonal, and reproductive effects.

Kodavanti PR, Coburn CG, Moser VC, MacPhail RC, Fenton SE, Stoker TE, Rayner JL, Kannan K, Birnbaum LS.

Toxicol Sci. 2010 Jul;116(1):297-312. doi: 10.1093/toxsci/kfq105. Epub 2010 Apr 7.


Loss of protein kinase C delta gene expression in human squamous cell carcinomas: a laser capture microdissection study.

Yadav V, Yanez NC, Fenton SE, Denning MF.

Am J Pathol. 2010 Mar;176(3):1091-6. doi: 10.2353/ajpath.2010.090816. Epub 2010 Jan 21.


Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life.

Hines EP, White SS, Stanko JP, Gibbs-Flournoy EA, Lau C, Fenton SE.

Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105. doi: 10.1016/j.mce.2009.02.021. Epub 2009 Mar 9.


Analysis of PFOA in dosed CD-1 mice. Part 2. Disposition of PFOA in tissues and fluids from pregnant and lactating mice and their pups.

Fenton SE, Reiner JL, Nakayama SF, Delinsky AD, Stanko JP, Hines EP, White SS, Lindstrom AB, Strynar MJ, Petropoulou SS.

Reprod Toxicol. 2009 Jun;27(3-4):365-72. doi: 10.1016/j.reprotox.2009.02.012. Epub 2009 Mar 9.


Polyfluoroalkyl chemicals in the serum and milk of breastfeeding women.

von Ehrenstein OS, Fenton SE, Kato K, Kuklenyik Z, Calafat AM, Hines EP.

Reprod Toxicol. 2009 Jun;27(3-4):239-45. doi: 10.1016/j.reprotox.2009.03.001. Epub 2009 Mar 6.


Human milk biomonitoring of phthalates: expanding our understanding of infant exposure is compatible with supporting breastfeeding.

LaKind JS, Fenton SE, Dórea JG.

Environ Int. 2009 Aug;35(6):994-5. doi: 10.1016/j.envint.2009.03.013. Epub 2009 Apr 23. No abstract available.


Evidence from the UK Zoonoses Action Plan in favour of localised anomalies of Salmonella infection on United Kingdom pig farms.

Clough HE, Fenton SE, French NP, Miller AJ, Cook AJ.

Prev Vet Med. 2009 May 1;89(1-2):67-74. doi: 10.1016/j.prevetmed.2009.01.008. Epub 2009 Mar 19.


Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women.

Hines EP, Calafat AM, Silva MJ, Mendola P, Fenton SE.

Environ Health Perspect. 2009 Jan;117(1):86-92. doi: 10.1289/ehp.11610. Epub 2008 Aug 22.


Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures.

White SS, Kato K, Jia LT, Basden BJ, Calafat AM, Hines EP, Stanko JP, Wolf CJ, Abbott BD, Fenton SE.

Reprod Toxicol. 2009 Jun;27(3-4):289-98. doi: 10.1016/j.reprotox.2008.11.054. Epub 2008 Nov 27.

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