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Items: 1 to 50 of 220

1.

Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium.

Christensen IB, Wu Q, Bohlbro AS, Skals MG, Damkier HH, Hübner CA, Fenton RA, Praetorius J.

Fluids Barriers CNS. 2020 Jan 7;17(1):2. doi: 10.1186/s12987-019-0162-5.

2.

Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion.

Keppner A, Maric D, Sergi C, Ansermet C, De Bellis D, Kratschmar DV, Canonica J, Klusonova P, Fenton RA, Odermatt A, Crambert G, Hoogewijs D, Hummler E.

Sci Rep. 2019 Dec 20;9(1):19540. doi: 10.1038/s41598-019-55995-x.

3.

Regulation of the Renal NaCl Cotransporter and Its Role in Potassium Homeostasis.

Hoorn EJ, Gritter M, Cuevas CA, Fenton RA.

Physiol Rev. 2020 Jan 1;100(1):321-356. doi: 10.1152/physrev.00044.2018.

PMID:
31793845
4.

Bilateral ureteral obstruction is rapidly accompanied by ER stress and activation of autophagic degradation of IMCD proteins, including AQP2.

Somparn P, Boonkrai C, Charngkaew K, Chomanee N, Hodge KG, Fenton RA, Pisitkun T, Khositseth S.

Am J Physiol Renal Physiol. 2020 Jan 1;318(1):F135-F147. doi: 10.1152/ajprenal.00113.2019. Epub 2019 Nov 18.

PMID:
31736351
5.

AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells.

Ho PY, Li H, Cheng L, Bhalla V, Fenton RA, Hallows KR.

Am J Physiol Renal Physiol. 2019 Dec 1;317(6):F1513-F1525. doi: 10.1152/ajprenal.00592.2018. Epub 2019 Sep 30.

PMID:
31566435
6.

SUMOylation Landscape of Renal Cortical Collecting Duct Cells.

Wu Q, Aroankins TS, Cheng L, Fenton RA.

J Proteome Res. 2019 Oct 4;18(10):3640-3648. doi: 10.1021/acs.jproteome.9b00306. Epub 2019 Sep 18.

PMID:
31502464
7.

Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function.

Thomas L, Xue J, Murali SK, Fenton RA, Dominguez Rieg JA, Rieg T.

J Am Soc Nephrol. 2019 Nov;30(11):2128-2139. doi: 10.1681/ASN.2018121250. Epub 2019 Aug 13.

PMID:
31409727
8.

Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus.

Saglar Ozer E, Moeller HB, Karaduman T, Fenton RA, Mergen H.

Cell Mol Life Sci. 2019 Jul 13. doi: 10.1007/s00018-019-03219-w. [Epub ahead of print]

PMID:
31302751
9.

K+ and the renin-angiotensin-aldosterone system: new insights into their role in blood pressure control and hypertension treatment.

Poulsen SB, Fenton RA.

J Physiol. 2019 Sep;597(17):4451-4464. doi: 10.1113/JP276844. Epub 2019 Jul 29.

PMID:
31294465
10.

Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter.

Cheng L, Poulsen SB, Wu Q, Esteva-Font C, Olesen ETB, Peng L, Olde B, Leeb-Lundberg LMF, Pisitkun T, Rieg T, Dimke H, Fenton RA.

J Am Soc Nephrol. 2019 Aug;30(8):1454-1470. doi: 10.1681/ASN.2018101025. Epub 2019 Jun 28.

PMID:
31253651
11.

Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention.

Raikwar N, Braverman C, Snyder PM, Fenton RA, Meyerholz DK, Abboud FM, Harwani SC.

Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H517-H530. doi: 10.1152/ajpheart.00234.2019. Epub 2019 Jun 7.

PMID:
31172810
12.

Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter.

Penton D, Moser S, Wengi A, Czogalla J, Rosenbaek LL, Rigendinger F, Faresse N, Martins JR, Fenton RA, Loffing-Cueni D, Loffing J.

J Am Soc Nephrol. 2019 May;30(5):737-750. doi: 10.1681/ASN.2018050540. Epub 2019 Mar 22.

PMID:
30902838
13.

The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance.

Murali SK, Aroankins TS, Moeller HB, Fenton RA.

Cells. 2019 Mar 21;8(3). pii: E265. doi: 10.3390/cells8030265.

14.

Proximal tubule transferrin uptake is modulated by cellular iron and mediated by apical membrane megalin-cubilin complex and transferrin receptor 1.

Smith CP, Lee WK, Haley M, Poulsen SB, Thévenod F, Fenton RA.

J Biol Chem. 2019 Apr 26;294(17):7025-7036. doi: 10.1074/jbc.RA118.006390. Epub 2019 Mar 4.

15.

Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin-Induced Diarrhea.

Fenton RA, Murali SK, Kaji I, Akiba Y, Kaunitz JD, Kristensen TB, Poulsen SB, Dominguez Rieg JA, Rieg T.

J Infect Dis. 2019 Oct 22;220(11):1719-1728. doi: 10.1093/infdis/jiz013.

PMID:
30624615
16.

Evaluation of the Intervention Initiative: A Bystander Intervention Program to Prevent Violence Against Women in Universities.

Fenton RA, Mott HL.

Violence Vict. 2018 Aug;33(4):645-662. doi: 10.1891/0886-6708.VV-D-16-00074.

PMID:
30567766
17.

Proteomic approaches in kidney disease biomarker discovery.

Fenton RA.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1817-F1821. doi: 10.1152/ajprenal.00421.2018. Epub 2018 Sep 19.

18.

Adenylyl cyclase 6 is required for maintaining acid-base homeostasis.

Poulsen SB, Marin De Evsikova C, Murali SK, Praetorius J, Chern Y, Fenton RA, Rieg T.

Clin Sci (Lond). 2018 Aug 30;132(16):1779-1796. doi: 10.1042/CS20180060. Print 2018 Aug 31.

19.

RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action.

Poulsen SB, Limbutara K, Fenton RA, Pisitkun T, Christensen BM.

Physiol Genomics. 2018 May 1;50(5):343-354. doi: 10.1152/physiolgenomics.00084.2017. Epub 2018 Mar 9.

20.

Author Correction: The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.

Rosenbaek LL, Rizzo F, Wu Q, Rojas-Vega L, Gamba G, MacAulay N, Staub O, Fenton RA.

Sci Rep. 2018 Mar 6;8(1):4215. doi: 10.1038/s41598-018-22153-8.

21.

The murine choroid plexus epithelium expresses the 2Cl-/H+ exchanger ClC-7 and Na+/H+ exchanger NHE6 in the luminal membrane domain.

Damkier HH, Christensen HL, Christensen IB, Wu Q, Fenton RA, Praetorius J.

Am J Physiol Cell Physiol. 2018 Apr 1;314(4):C439-C448. doi: 10.1152/ajpcell.00145.2017. Epub 2017 Dec 20.

22.

CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis.

Wu Q, Moeller HB, Stevens DA, Sanchez-Hodge R, Childers G, Kortenoeven MLA, Cheng L, Rosenbaek LL, Rubel C, Patterson C, Pisitkun T, Schisler JC, Fenton RA.

J Am Soc Nephrol. 2018 Mar;29(3):936-948. doi: 10.1681/ASN.2017050526. Epub 2017 Dec 14.

23.

Basolateral cholesterol depletion alters Aquaporin-2 post-translational modifications and disrupts apical plasma membrane targeting.

Moeller HB, Fuglsang CH, Pedersen CN, Fenton RA.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):157-162. doi: 10.1016/j.bbrc.2017.11.002. Epub 2017 Nov 2.

PMID:
29103957
24.

The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.

Rosenbaek LL, Rizzo F, Wu Q, Rojas-Vega L, Gamba G, MacAulay N, Staub O, Fenton RA.

Sci Rep. 2017 Oct 11;7(1):12981. doi: 10.1038/s41598-017-12819-0. Erratum in: Sci Rep. 2018 Mar 6;8(1):4215.

25.

A Treatment Algorithm for Patients Presenting with Sagittal Craniosynostosis after the Age of 1 Year.

Ruane EJ, Garland CB, Camison L, Fenton RA, Nischal KK, Pollack IF, Tamber MS, Grunwaldt LJ, Losee JE, Goldstein JA.

Plast Reconstr Surg. 2017 Sep;140(3):582-590. doi: 10.1097/PRS.0000000000003602.

PMID:
28841620
26.

Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.

Rosenbaek LL, Rizzo F, MacAulay N, Staub O, Fenton RA.

Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F495-F504. doi: 10.1152/ajprenal.00088.2017. Epub 2017 May 17.

27.

NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity.

Tutakhel OAZ, Moes AD, Valdez-Flores MA, Kortenoeven MLA, Vrie MVD, Jeleń S, Fenton RA, Zietse R, Hoenderop JGJ, Hoorn EJ, Hilbrands L, Bindels RJM.

PLoS One. 2017 Apr 21;12(4):e0176220. doi: 10.1371/journal.pone.0176220. eCollection 2017.

28.

Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus.

Poulsen SB, Kristensen TB, Brooks HL, Kohan DE, Rieg T, Fenton RA.

JCI Insight. 2017 Apr 6;2(7):e91042. doi: 10.1172/jci.insight.91042.

29.

Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.

Fenton RA, Poulsen SB, de la Mora Chavez S, Soleimani M, Dominguez Rieg JA, Rieg T.

Kidney Int. 2017 Aug;92(2):397-414. doi: 10.1016/j.kint.2017.02.001. Epub 2017 Apr 3.

30.

Aquaporin-2 membrane targeting: still a conundrum.

Olesen ET, Fenton RA.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F744-F747. doi: 10.1152/ajprenal.00010.2017. Epub 2017 Feb 8. Review.

31.

Hypercalcemia induces targeted autophagic degradation of aquaporin-2 at the onset of nephrogenic diabetes insipidus.

Khositseth S, Charngkaew K, Boonkrai C, Somparn P, Uawithya P, Chomanee N, Payne DM, Fenton RA, Pisitkun T.

Kidney Int. 2017 May;91(5):1070-1087. doi: 10.1016/j.kint.2016.12.005. Epub 2017 Jan 27.

PMID:
28139295
32.

The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway.

Olesen ET, Moeller HB, Assentoft M, MacAulay N, Fenton RA.

Am J Physiol Renal Physiol. 2016 Nov 1;311(5):F935-F944. doi: 10.1152/ajprenal.00559.2015. Epub 2016 Aug 24.

33.

Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells.

Al-Bataineh MM, Li H, Ohmi K, Gong F, Marciszyn AL, Naveed S, Zhu X, Neumann D, Wu Q, Cheng L, Fenton RA, Pastor-Soler NM, Hallows KR.

Am J Physiol Renal Physiol. 2016 Nov 1;311(5):F890-F900. doi: 10.1152/ajprenal.00308.2016. Epub 2016 Aug 17.

34.

Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids.

Yde J, Keely S, Wu Q, Borg JF, Lajczak N, O'Dwyer A, Dalsgaard P, Fenton RA, Moeller HB.

Front Nutr. 2016 Oct 10;3:46. eCollection 2016.

35.

Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease.

Rützler M, Rojek A, Damgaard MV, Andreasen A, Fenton RA, Nielsen S.

Am J Physiol Renal Physiol. 2017 Feb 1;312(2):F343-F351. doi: 10.1152/ajprenal.00065.2016. Epub 2016 Aug 31.

36.

In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance.

Wolley MJ, Wu A, Xu S, Gordon RD, Fenton RA, Stowasser M.

J Am Soc Nephrol. 2017 Jan;28(1):56-63. doi: 10.1681/ASN.2015111221. Epub 2016 Jul 5.

37.

Renal aquaporins and water balance disorders.

Moeller HB, Fuglsang CH, Fenton RA.

Best Pract Res Clin Endocrinol Metab. 2016 Mar;30(2):277-88. doi: 10.1016/j.beem.2016.02.012. Epub 2016 Mar 2. Review.

PMID:
27156764
38.

Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Landegren N, Pourmousa Lindberg M, Skov J, Hallgren Å, Eriksson D, Lisberg Toft-Bertelsen T, MacAulay N, Hagforsen E, Räisänen-Sokolowski A, Saha H, Nilsson T, Nordmark G, Ohlsson S, Gustafsson J, Husebye ES, Larsson E, Anderson MS, Perheentupa J, Rorsman F, Fenton RA, Kämpe O.

J Am Soc Nephrol. 2016 Oct;27(10):3220-3228. Epub 2016 Mar 16.

39.

Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation.

Huebner AR, Cheng L, Somparn P, Knepper MA, Fenton RA, Pisitkun T.

Mol Cell Proteomics. 2016 May;15(5):1556-71. doi: 10.1074/mcp.M115.054965. Epub 2016 Feb 16.

40.

An immunoassay for urinary extracellular vesicles.

Salih M, Fenton RA, Knipscheer J, Janssen JW, Vredenbregt-van den Berg MS, Jenster G, Zietse R, Hoorn EJ.

Am J Physiol Renal Physiol. 2016 Apr 15;310(8):F796-F801. doi: 10.1152/ajprenal.00463.2015. Epub 2016 Jan 28.

41.

Urinary extracellular vesicles as markers to assess kidney sodium transport.

Salih M, Fenton RA, Zietse R, Hoorn EJ.

Curr Opin Nephrol Hypertens. 2016 Mar;25(2):67-72. doi: 10.1097/MNH.0000000000000192. Review.

PMID:
26717312
42.

Mucin-mediated nanocarrier disassembly for triggered uptake of oligonucleotides as a delivery strategy for the potential treatment of mucosal tumours.

Martirosyan A, Olesen MJ, Fenton RA, Kjems J, Howard KA.

Nanoscale. 2016 Jul 7;8(25):12599-607. doi: 10.1039/c5nr07206a. Epub 2015 Dec 22.

PMID:
26694897
43.

Autophagic degradation of aquaporin-2 is an early event in hypokalemia-induced nephrogenic diabetes insipidus.

Khositseth S, Uawithya P, Somparn P, Charngkaew K, Thippamom N, Hoffert JD, Saeed F, Michael Payne D, Chen SH, Fenton RA, Pisitkun T.

Sci Rep. 2015 Dec 17;5:18311. doi: 10.1038/srep18311.

44.

Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and -ζ.

Moeller HB, Slengerik-Hansen J, Aroankins T, Assentoft M, MacAulay N, Moestrup SK, Bhalla V, Fenton RA.

J Biol Chem. 2016 Jan 29;291(5):2469-84. doi: 10.1074/jbc.M115.691121. Epub 2015 Dec 8.

45.

H95 Is a pH-Dependent Gate in Aquaporin 4.

Kaptan S, Assentoft M, Schneider HP, Fenton RA, Deitmer JW, MacAulay N, de Groot BL.

Structure. 2015 Dec 1;23(12):2309-2318. doi: 10.1016/j.str.2015.08.020. Epub 2015 Nov 12.

46.

The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.

Schepelmann M, Yarova PL, Lopez-Fernandez I, Davies TS, Brennan SC, Edwards PJ, Aggarwal A, Graça J, Rietdorf K, Matchkov V, Fenton RA, Chang W, Krssak M, Stewart A, Broadley KJ, Ward DT, Price SA, Edwards DH, Kemp PJ, Riccardi D.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C193-204. doi: 10.1152/ajpcell.00248.2015. Epub 2015 Nov 4.

47.

Vasopressin receptors V1a and V2 are not osmosensors.

Lykke K, Assentoft M, Fenton RA, Rosenkilde MM, MacAulay N.

Physiol Rep. 2015 Aug;3(8). pii: e12519. doi: 10.14814/phy2.12519.

48.

A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells.

Cheng L, Wu Q, Kortenoeven MLA, Pisitkun T, Fenton RA.

Sci Rep. 2015 Aug 4;5:12829. doi: 10.1038/srep12829.

49.

Changes in urinary excretion of water and sodium transporters during amiloride and bendroflumethiazide treatment.

Jensen JM, Mose FH, Kulik AE, Bech JN, Fenton RA, Pedersen EB.

World J Nephrol. 2015 Jul 6;4(3):423-37. doi: 10.5527/wjn.v4.i3.423.

50.

Sodium-glucose cotransport.

Poulsen SB, Fenton RA, Rieg T.

Curr Opin Nephrol Hypertens. 2015 Sep;24(5):463-9. doi: 10.1097/MNH.0000000000000152. Review.

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