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Items: 34

1.

Multilevel structure-activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism.

Fenteany G, Gaur P, Hegedűs L, Dudás K, Kiss E, Wéber E, Hackler L, Martinek T, Puskás LG, Haracska L.

Sci Rep. 2019 Sep 5;9(1):12801. doi: 10.1038/s41598-019-48888-6.

2.

Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root.

Powell D, Inoue T, Bahtiyar G, Fenteany G, Sacerdote A.

Case Rep Endocrinol. 2017;2017:1869560. doi: 10.1155/2017/1869560. Epub 2017 Jun 20.

3.

Cardiac glycoside activities link Na(+)/K(+) ATPase ion-transport to breast cancer cell migration via correlative SAR.

Magpusao AN, Omolloh G, Johnson J, Gascón J, Peczuh MW, Fenteany G.

ACS Chem Biol. 2015 Feb 20;10(2):561-9. doi: 10.1021/cb500665r. Epub 2014 Nov 26.

4.

Identification of small molecule inhibitors of cytokinesis and single cell wound repair.

Clark AG, Sider JR, Verbrugghe K, Fenteany G, von Dassow G, Bement WM.

Cytoskeleton (Hoboken). 2012 Nov;69(11):1010-20. doi: 10.1002/cm.21085. Epub 2012 Nov 1.

5.

Recognition and reactivity in the binding between Raf kinase inhibitor protein and its small-molecule inhibitor locostatin.

Rudnitskaya AN, Eddy NA, Fenteany G, Gascón JA.

J Phys Chem B. 2012 Aug 30;116(34):10176-81. doi: 10.1021/jp303140j. Epub 2012 Aug 15.

PMID:
22861375
6.

Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer.

Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, Yeung KC.

Cancer Res. 2012 Jun 15;72(12):3091-104. doi: 10.1158/0008-5472.CAN-11-3546. Epub 2012 Apr 13.

7.

Access to dienophilic ene-triketone synthons by oxidation of diketones with an oxoammonium salt.

Eddy NA, Kelly CB, Mercadante MA, Leadbeater NE, Fenteany G.

Org Lett. 2012 Jan 20;14(2):498-501. doi: 10.1021/ol2030873. Epub 2011 Dec 29.

8.
9.

Synthesis of Oxazolidinone and Tosyl Enamines by Tertiary Amine Catalysis.

Eddy NA, Morse PD, Morton MD, Fenteany G.

Synlett. 2011 Jan 1;5:699-701.

10.

Diversity through a branched reaction pathway: generation of multicyclic scaffolds and identification of antimigratory agents.

Wang Z, Castellano S, Kinderman SS, Argueta CE, Beshir AB, Fenteany G, Kwon O.

Chemistry. 2011 Jan 10;17(2):649-54. doi: 10.1002/chem.201002195. Epub 2010 Nov 9.

11.

Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics.

Knecht DA, LaFleur RA, Kahsai AW, Argueta CE, Beshir AB, Fenteany G.

PLoS One. 2010 Nov 24;5(11):e14039. doi: 10.1371/journal.pone.0014039.

12.

Raf kinase inhibitor protein suppresses nuclear factor-κB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.

Beshir AB, Ren G, Magpusao AN, Barone LM, Yeung KC, Fenteany G.

Cancer Lett. 2010 Dec 28;299(2):137-49. doi: 10.1016/j.canlet.2010.08.012. Epub 2010 Sep 19.

13.

Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones.

Magpusao AN, Desmond RT, Billings KJ, Fenteany G, Peczuh MW.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5472-6. doi: 10.1016/j.bmcl.2010.07.083. Epub 2010 Jul 25.

14.

The oxazolidinone derivative locostatin induces cytokine appeasement.

Ménoret A, McAleer JP, Ngoi SM, Ray S, Eddy NA, Fenteany G, Lee SJ, Rossi RJ, Mukherji B, Allen DL, Chakraborty NG, Vella AT.

J Immunol. 2009 Dec 1;183(11):7489-96. doi: 10.4049/jimmunol.0901414. Epub 2009 Nov 16.

15.

G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells.

Kahsai AW, Zhu S, Fenteany G.

Biochim Biophys Acta. 2010 Feb;1803(2):300-10. doi: 10.1016/j.bbamcr.2009.11.002. Epub 2009 Nov 11.

16.

Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site.

Kahsai AW, Cui J, Kaniskan HU, Garner PP, Fenteany G.

J Biol Chem. 2008 Sep 5;283(36):24534-45. doi: 10.1074/jbc.M800006200. Epub 2008 Jun 13.

17.

Synthesis and structure-activity relationships of metal-ligand complexes that potently inhibit cell migration.

Beshir AB, Guchhait SK, Gascón JA, Fenteany G.

Bioorg Med Chem Lett. 2008 Jan 15;18(2):498-504.

PMID:
18240381
18.

Raf kinase inhibitor protein positively regulates cell-substratum adhesion while negatively regulating cell-cell adhesion.

Mc Henry KT, Montesano R, Zhu S, Beshir AB, Tang HH, Yeung KC, Fenteany G.

J Cell Biochem. 2008 Feb 15;103(3):972-85.

PMID:
17668446
19.
20.

Cell surface actin remodeling.

Stossel TP, Fenteany G, Hartwig JH.

J Cell Sci. 2006 Aug 15;119(Pt 16):3261-4. No abstract available.

21.

Glycogen synthase kinase-3 acts upstream of ADP-ribosylation factor 6 and Rac1 to regulate epithelial cell migration.

Farooqui R, Zhu S, Fenteany G.

Exp Cell Res. 2006 May 15;312(9):1514-25. Epub 2006 Mar 9.

PMID:
16529739
22.

A chemical inhibitor reveals the role of Raf kinase inhibitor protein in cell migration.

Zhu S, Mc Henry KT, Lane WS, Fenteany G.

Chem Biol. 2005 Sep;12(9):981-91.

23.
25.

Cytoskeletal remodeling in leukocyte function.

Fenteany G, Glogauer M.

Curr Opin Hematol. 2004 Jan;11(1):15-24. Review. Erratum in: Curr Opin Hematol. 2004 Mar;11(2):112.

PMID:
14676623
26.

Small-molecule inhibitors of actin dynamics and cell motility.

Fenteany G, Zhu S.

Curr Top Med Chem. 2003;3(6):593-616. Review.

PMID:
12570855
27.

A non-antibacterial oxazolidinone derivative that inhibits epithelial cell sheet migration.

Mc Henry KT, Ankala SV, Ghosh AK, Fenteany G.

Chembiochem. 2002 Nov 4;3(11):1105-11.

PMID:
12404636
28.

Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets.

Fenteany G, Janmey PA, Stossel TP.

Curr Biol. 2000 Jul 13;10(14):831-8.

29.

Lactacystin, proteasome function, and cell fate.

Fenteany G, Schreiber SL.

J Biol Chem. 1998 Apr 10;273(15):8545-8. Review. No abstract available.

30.
32.

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin.

Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL.

Science. 1995 May 5;268(5211):726-31.

PMID:
7732382
33.

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.

Fenteany G, Standaert RF, Reichard GA, Corey EJ, Schreiber SL.

Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3358-62.

34.

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