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Items: 1 to 50 of 110

1.

The Swiss Chemical Society Establishes a New Section on 'Chemistry and the Environment' (SCE).

Fenner K.

Chimia (Aarau). 2019 Aug 21;73(7):644. doi: 10.2533/chimia.2019.644. No abstract available.

PMID:
31431227
2.

It's all about the sex, or is it? Humans, horses and temperament.

Fenner K, Caspar G, Hyde M, Henshall C, Dhand N, Probyn-Rapsey F, Dashper K, McLean A, McGreevy P.

PLoS One. 2019 May 14;14(5):e0216699. doi: 10.1371/journal.pone.0216699. eCollection 2019.

3.

Microbial residence time is a controlling parameter of the taxonomic composition and functional profile of microbial communities.

Mansfeldt C, Achermann S, Men Y, Walser JC, Villez K, Joss A, Johnson DR, Fenner K.

ISME J. 2019 Jun;13(6):1589-1601. doi: 10.1038/s41396-019-0371-6. Epub 2019 Feb 20.

4.

Trends in Micropollutant Biotransformation along a Solids Retention Time Gradient.

Achermann S, Falås P, Joss A, Mansfeldt CB, Men Y, Vogler B, Fenner K.

Environ Sci Technol. 2018 Oct 16;52(20):11601-11611. doi: 10.1021/acs.est.8b02763. Epub 2018 Oct 1.

PMID:
30208701
5.

Evaluating the environmental parameters that determine aerobic biodegradation half-lives of pesticides in soil with a multivariable approach.

Wang Y, Lai A, Latino D, Fenner K, Helbling DE.

Chemosphere. 2018 Oct;209:430-438. doi: 10.1016/j.chemosphere.2018.06.077. Epub 2018 Jun 14.

PMID:
29936116
6.

Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity.

Zou L, Stecula A, Gupta A, Prasad B, Chien HC, Yee SW, Wang L, Unadkat JD, Stahl SH, Fenner KS, Giacomini KM.

Mol Pharmacol. 2018 Jul;94(1):689-699. doi: 10.1124/mol.117.111153. Epub 2018 May 2.

7.

Biotransformation of Sulfonamide Antibiotics in Activated Sludge: The Formation of Pterin-Conjugates Leads to Sustained Risk.

Achermann S, Bianco V, Mansfeldt CB, Vogler B, Kolvenbach BA, Corvini PFX, Fenner K.

Environ Sci Technol. 2018 Jun 5;52(11):6265-6274. doi: 10.1021/acs.est.7b06716. Epub 2018 May 15.

PMID:
29706069
8.

Current State of In vitro Cell-Based Renal Models.

Gozalpour E, Fenner KS.

Curr Drug Metab. 2018;19(4):310-326. doi: 10.2174/1389200219666180119115133. Review.

PMID:
29357789
9.

Ion Trapping of Amines in Protozoa: A Novel Removal Mechanism for Micropollutants in Activated Sludge.

Gulde R, Anliker S, Kohler HE, Fenner K.

Environ Sci Technol. 2018 Jan 2;52(1):52-60. doi: 10.1021/acs.est.7b03556. Epub 2017 Dec 13.

PMID:
29182849
10.

Effects of pre-conditioning on behavior and physiology of horses during a standardised learning task.

Fenner K, Webb H, Starling MJ, Freire R, Buckley P, McGreevy PD.

PLoS One. 2017 Mar 30;12(3):e0174313. doi: 10.1371/journal.pone.0174313. eCollection 2017.

11.

QSARs and computational chemistry methods in environmental chemical sciences.

Fenner K, Tratnyek PG.

Environ Sci Process Impacts. 2017 Mar 22;19(3):185-187. doi: 10.1039/c7em90008b. No abstract available.

PMID:
28293683
12.

Eawag-Soil in enviPath: a new resource for exploring regulatory pesticide soil biodegradation pathways and half-life data.

Latino DA, Wicker J, Gütlein M, Schmid E, Kramer S, Fenner K.

Environ Sci Process Impacts. 2017 Mar 22;19(3):449-464. doi: 10.1039/c6em00697c.

PMID:
28229138
13.

A computer-based prediction platform for the reaction of ozone with organic compounds in aqueous solution: kinetics and mechanisms.

Lee M, Blum LC, Schmid E, Fenner K, von Gunten U.

Environ Sci Process Impacts. 2017 Mar 22;19(3):465-476. doi: 10.1039/c6em00584e.

PMID:
28191571
14.

Relative contribution of ammonia oxidizing bacteria and other members of nitrifying activated sludge communities to micropollutant biotransformation.

Men Y, Achermann S, Helbling DE, Johnson DR, Fenner K.

Water Res. 2017 Feb 1;109:217-226. doi: 10.1016/j.watres.2016.11.048. Epub 2016 Nov 22.

PMID:
27898334
15.

Identification of biotransformation products of citalopram formed in activated sludge.

Beretsou VG, Psoma AK, Gago-Ferrero P, Aalizadeh R, Fenner K, Thomaidis NS.

Water Res. 2016 Oct 15;103:205-214. doi: 10.1016/j.watres.2016.07.029. Epub 2016 Jul 14.

PMID:
27459150
16.

Simulation Studies to Explore Biodegradation in Water-Sediment Systems: From OECD 308 to OECD 309.

Shrestha P, Junker T, Fenner K, Hahn S, Honti M, Bakkour R, Diaz C, Hennecke D.

Environ Sci Technol. 2016 Jul 5;50(13):6856-64. doi: 10.1021/acs.est.6b01095. Epub 2016 Jun 23.

PMID:
27337495
17.

Can meta-omics help to establish causality between contaminant biotransformations and genes or gene products?

Johnson DR, Helbling DE, Men Y, Fenner K.

Environ Sci (Camb). 2015 May 1;1(3):272-278. Epub 2015 Mar 25.

18.

Bridging across OECD 308 and 309 Data in Search of a Robust Biotransformation Indicator.

Honti M, Hahn S, Hennecke D, Junker T, Shrestha P, Fenner K.

Environ Sci Technol. 2016 Jul 5;50(13):6865-72. doi: 10.1021/acs.est.6b01097. Epub 2016 Jun 14.

PMID:
27213716
19.

The Effect of Noseband Tightening on Horses' Behavior, Eye Temperature, and Cardiac Responses.

Fenner K, Yoon S, White P, Starling M, McGreevy P.

PLoS One. 2016 May 3;11(5):e0154179. doi: 10.1371/journal.pone.0154179. eCollection 2016.

20.

Biotransformation of Two Pharmaceuticals by the Ammonia-Oxidizing Archaeon Nitrososphaera gargensis.

Men Y, Han P, Helbling DE, Jehmlich N, Herbold C, Gulde R, Onnis-Hayden A, Gu AZ, Johnson DR, Wagner M, Fenner K.

Environ Sci Technol. 2016 May 3;50(9):4682-92. doi: 10.1021/acs.est.5b06016. Epub 2016 Apr 19.

21.

Rapid Screening for Exposure to "Non-Target" Pharmaceuticals from Wastewater Effluents by Combining HRMS-Based Suspect Screening and Exposure Modeling.

Singer HP, Wössner AE, McArdell CS, Fenner K.

Environ Sci Technol. 2016 Jul 5;50(13):6698-707. doi: 10.1021/acs.est.5b03332. Epub 2016 Mar 17.

PMID:
26938046
22.

Systematic Exploration of Biotransformation Reactions of Amine-Containing Micropollutants in Activated Sludge.

Gulde R, Meier U, Schymanski EL, Kohler HP, Helbling DE, Derrer S, Rentsch D, Fenner K.

Environ Sci Technol. 2016 Mar 15;50(6):2908-20. doi: 10.1021/acs.est.5b05186. Epub 2016 Feb 26.

PMID:
26864277
23.

Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure.

Elsby R, Martin P, Surry D, Sharma P, Fenner K.

Drug Metab Dispos. 2016 Mar;44(3):398-408. doi: 10.1124/dmd.115.066795. Epub 2015 Dec 23.

PMID:
26700956
24.

enviPath--The environmental contaminant biotransformation pathway resource.

Wicker J, Lorsbach T, Gütlein M, Schmid E, Latino D, Kramer S, Fenner K.

Nucleic Acids Res. 2016 Jan 4;44(D1):D502-8. doi: 10.1093/nar/gkv1229. Epub 2015 Nov 17.

25.

Exploring the Behaviour of Emerging Contaminants in the Water Cycle using the Capabilities of High Resolution Mass Spectrometry.

Hollender J, Bourgin M, Fenner KB, Longrée P, Mcardell CS, Moschet C, Ruff M, Schymanski EL, Singer HP.

Chimia (Aarau). 2014 Nov;68(11):793-8. doi: 10.2533/chimia.2014.793.

PMID:
26508487
26.

Development of Prediction Models for the Reactivity of Organic Compounds with Ozone in Aqueous Solution by Quantum Chemical Calculations: The Role of Delocalized and Localized Molecular Orbitals.

Lee M, Zimmermann-Steffens SG, Arey JS, Fenner K, von Gunten U.

Environ Sci Technol. 2015 Aug 18;49(16):9925-35. doi: 10.1021/acs.est.5b00902. Epub 2015 Aug 7.

PMID:
26121114
27.

Deriving persistence indicators from regulatory water-sediment studies – opportunities and limitations in OECD 308 data.

Honti M, Fenner K.

Environ Sci Technol. 2015 May 19;49(10):5879-86. doi: 10.1021/acs.est.5b00788. Epub 2015 May 11.

PMID:
25958980
28.

A framework for establishing predictive relationships between specific bacterial 16S rRNA sequence abundances and biotransformation rates.

Helbling DE, Johnson DR, Lee TK, Scheidegger A, Fenner K.

Water Res. 2015 Mar 1;70:471-84. doi: 10.1016/j.watres.2014.12.013. Epub 2014 Dec 16.

PMID:
25594727
29.

Association of biodiversity with the rates of micropollutant biotransformations among full-scale wastewater treatment plant communities.

Johnson DR, Helbling DE, Lee TK, Park J, Fenner K, Kohler HP, Ackermann M.

Appl Environ Microbiol. 2015 Jan;81(2):666-75. doi: 10.1128/AEM.03286-14. Epub 2014 Nov 14.

30.

pH-dependent biotransformation of ionizable organic micropollutants in activated sludge.

Gulde R, Helbling DE, Scheidegger A, Fenner K.

Environ Sci Technol. 2014 Dec 2;48(23):13760-8. doi: 10.1021/es5037139. Epub 2014 Nov 12.

PMID:
25337862
31.

Estimated radiation exposure and cancer risk from CT and PET/CT scans in patients with lymphoma.

Guttikonda R, Herts BR, Dong F, Baker ME, Fenner KB, Pohlman B.

Eur J Radiol. 2014 Jun;83(6):1011-1015. doi: 10.1016/j.ejrad.2014.02.015. Epub 2014 Feb 24.

PMID:
24656401
32.

Flow cytometric analysis of cerebrospinal fluid has low diagnostic yield in samples without atypical morphology or prior history of hematologic malignancy.

Collie AM, Hill BT, Stevens GH, Fenner K, Gazdick E, Hsi ED.

Am J Clin Pathol. 2014 Apr;141(4):515-21. doi: 10.1309/AJCP8IB8FRQDVPXL.

PMID:
24619752
33.

The functional and taxonomic richness of wastewater treatment plant microbial communities are associated with each other and with ambient nitrogen and carbon availability.

Johnson DR, Lee TK, Park J, Fenner K, Helbling DE.

Environ Microbiol. 2015 Dec;17(12):4851-60. doi: 10.1111/1462-2920.12429. Epub 2014 Mar 19.

PMID:
24552172
34.

Identifying small molecules via high resolution mass spectrometry: communicating confidence.

Schymanski EL, Jeon J, Gulde R, Fenner K, Ruff M, Singer HP, Hollender J.

Environ Sci Technol. 2014 Feb 18;48(4):2097-8. doi: 10.1021/es5002105. Epub 2014 Jan 29. No abstract available.

PMID:
24476540
35.

Evaluating pesticide degradation in the environment: blind spots and emerging opportunities.

Fenner K, Canonica S, Wackett LP, Elsner M.

Science. 2013 Aug 16;341(6147):752-8. doi: 10.1126/science.1236281. Review.

PMID:
23950532
36.

Response to comment of Sierra Rayne on "Targeting aquatic microcontaminants for monitoring: exposure categorization and application to the Swiss situation [Götz et al., Environ Sci Pollut Res (2010) 17:341-354]".

Götz CW, Fenner K, Hollender J.

Environ Sci Pollut Res Int. 2013 Sep;20(9):6678-80. doi: 10.1007/s11356-013-1873-9. Epub 2013 Jun 9. No abstract available.

PMID:
23749203
37.

The use of bioreactors as in vitro models in pharmaceutical research.

Ginai M, Elsby R, Hewitt CJ, Surry D, Fenner K, Coopman K.

Drug Discov Today. 2013 Oct;18(19-20):922-35. doi: 10.1016/j.drudis.2013.05.016. Epub 2013 Jun 5. Review.

PMID:
23748137
38.

In vitro characterization of axitinib interactions with human efflux and hepatic uptake transporters: implications for disposition and drug interactions.

Reyner EL, Sevidal S, West MA, Clouser-Roche A, Freiwald S, Fenner K, Ullah M, Lee CA, Smith BJ.

Drug Metab Dispos. 2013 Aug;41(8):1575-83. doi: 10.1124/dmd.113.051193. Epub 2013 May 31.

PMID:
23729661
39.

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.

Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium.

Clin Pharmacol Ther. 2013 Jul;94(1):126-41. doi: 10.1038/clpt.2013.78. Epub 2013 Apr 10. Review.

40.

Understanding the critical disposition pathways of statins to assess drug-drug interaction risk during drug development: it's not just about OATP1B1.

Elsby R, Hilgendorf C, Fenner K.

Clin Pharmacol Ther. 2012 Nov;92(5):584-98. doi: 10.1038/clpt.2012.163. Epub 2012 Oct 10. Review.

PMID:
23047648
41.

Micropollutant biotransformation kinetics associate with WWTP process parameters and microbial community characteristics.

Helbling DE, Johnson DR, Honti M, Fenner K.

Environ Sci Technol. 2012 Oct 2;46(19):10579-88. doi: 10.1021/es3019012. Epub 2012 Sep 14.

PMID:
22938719
42.

Pesticide nonextractable residue formation in soil: insights from inverse modeling of degradation time series.

Loos M, Krauss M, Fenner K.

Environ Sci Technol. 2012 Sep 18;46(18):9830-7. doi: 10.1021/es300505r. Epub 2012 Sep 5.

PMID:
22891938
43.

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design.

Di L, Keefer C, Scott DO, Strelevitz TJ, Chang G, Bi YA, Lai Y, Duckworth J, Fenner K, Troutman MD, Obach RS.

Eur J Med Chem. 2012 Nov;57:441-8. doi: 10.1016/j.ejmech.2012.06.043. Epub 2012 Jul 16.

PMID:
22840492
44.

pH-Dependent solubility and permeability criteria for provisional biopharmaceutics classification (BCS and BDDCS) in early drug discovery.

Varma MV, Gardner I, Steyn SJ, Nkansah P, Rotter CJ, Whitney-Pickett C, Zhang H, Di L, Cram M, Fenner KS, El-Kattan AF.

Mol Pharm. 2012 May 7;9(5):1199-212. doi: 10.1021/mp2004912. Epub 2012 Apr 26.

PMID:
22489626
45.

In vitro evaluation of hepatic transporter-mediated clinical drug-drug interactions: hepatocyte model optimization and retrospective investigation.

Bi YA, Kimoto E, Sevidal S, Jones HM, Barton HA, Kempshall S, Whalen KM, Zhang H, Ji C, Fenner KS, El-Kattan AF, Lai Y.

Drug Metab Dispos. 2012 Jun;40(6):1085-92. doi: 10.1124/dmd.111.043489. Epub 2012 Mar 1. Review.

PMID:
22381335
46.

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS.

Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16.

PMID:
22344703
47.

Light stimuli control neuronal migration by altering of insulin-like growth factor 1 (IGF-1) signaling.

Li Y, Komuro Y, Fahrion JK, Hu T, Ohno N, Fenner KB, Wooton J, Raoult E, Galas L, Vaudry D, Komuro H.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2630-5. doi: 10.1073/pnas.1111326109. Epub 2012 Jan 30.

48.

The activity level of a microbial community function can be predicted from its metatranscriptome.

Helbling DE, Ackermann M, Fenner K, Kohler HP, Johnson DR.

ISME J. 2012 Apr;6(4):902-4. doi: 10.1038/ismej.2011.158. Epub 2011 Nov 17.

49.

The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance.

Fenner KS, Jones HM, Ullah M, Kempshall S, Dickins M, Lai Y, Morgan P, Barton HA.

Xenobiotica. 2012 Jan;42(1):28-45. doi: 10.3109/00498254.2011.626464. Epub 2011 Nov 11. Review.

PMID:
22077101
50.

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum.

Tucker TG, Milne AM, Fournel-Gigleux S, Fenner KS, Coughtrie MW.

Biochem Pharmacol. 2012 Jan 15;83(2):279-85. doi: 10.1016/j.bcp.2011.10.017. Epub 2011 Oct 31.

PMID:
22062654

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