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Items: 13


ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.

Ojha R, Leli NM, Onorati A, Piao S, Verginadis II, Tameire F, Rebecca VW, Chude CI, Murugan S, Fennelly C, Noguera-Ortega E, Chu CT, Liu S, Xu X, Krepler C, Xiao M, Xu W, Wei Z, Frederick DT, Boland G, Mitchell TC, Karakousis GC, Schuchter LM, Flaherty KT, Zhang G, Herlyn M, Koumenis C, Amaravadi RK.

Cancer Discov. 2019 Mar;9(3):396-415. doi: 10.1158/2159-8290.CD-18-0348. Epub 2018 Dec 18. Erratum in: Cancer Discov. 2019 Jul;9(7):981.


PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.

Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, Lee JJ, Schuchter LM, Xu X, Herlyn M, Marmorstein R, Gimotty PA, Speicher DW, Winkler JD, Amaravadi RK.

Cancer Discov. 2019 Feb;9(2):220-229. doi: 10.1158/2159-8290.CD-18-0706. Epub 2018 Nov 15.


A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.

Rebecca VW, Nicastri MC, McLaughlin N, Fennelly C, McAfee Q, Ronghe A, Nofal M, Lim CY, Witze E, Chude CI, Zhang G, Alicea GM, Piao S, Murugan S, Ojha R, Levi SM, Wei Z, Barber-Rotenberg JS, Murphy ME, Mills GB, Lu Y, Rabinowitz J, Marmorstein R, Liu Q, Liu S, Xu X, Herlyn M, Zoncu R, Brady DC, Speicher DW, Winkler JD, Amaravadi RK.

Cancer Discov. 2017 Nov;7(11):1266-1283. doi: 10.1158/2159-8290.CD-17-0741. Epub 2017 Sep 12.


Lysosomal Biology in Cancer.

Fennelly C, Amaravadi RK.

Methods Mol Biol. 2017;1594:293-308. doi: 10.1007/978-1-4939-6934-0_19. Review.


An in vitro culture system that supports robust expansion and maintenance of in vivo engraftment capabilities for myogenic progenitor cells from adult mice.

Wang Z, Cheung D, Zhou Y, Han C, Fennelly C, Criswell T, Soker S.

Biores Open Access. 2014 Jun 1;3(3):79-87. doi: 10.1089/biores.2014.0007.


YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment.

Basu A, Wilkinson FH, Colavita K, Fennelly C, Atchison ML.

Nucleic Acids Res. 2014 Feb;42(4):2208-23. doi: 10.1093/nar/gkt1187. Epub 2013 Nov 26.


In vitro and in vivo testing of a novel recessed-step catheter for reflux-free convection-enhanced drug delivery to the brain.

Gill T, Barua NU, Woolley M, Bienemann AS, Johnson DE, S O'Sullivan, Murray G, Fennelly C, Lewis O, Irving C, Wyatt MJ, Moore P, Gill SS.

J Neurosci Methods. 2013 Sep 30;219(1):1-9. doi: 10.1016/j.jneumeth.2013.06.008. Epub 2013 Jul 5.


Intermittent convection-enhanced delivery to the brain through a novel transcutaneous bone-anchored port.

Barua NU, Woolley M, Bienemann AS, Johnson DE, Lewis O, Wyatt MJ, Irving C, O'Sullivan S, Murray G, Fennelly C, Skinner P, Gill SS.

J Neurosci Methods. 2013 Apr 15;214(2):223-32. doi: 10.1016/j.jneumeth.2013.02.007. Epub 2013 Feb 16.


40-Gbit/s all-optical circulating shift register with an inverter.

Hall KL, Donnelly JP, Groves SH, Fennelly CI, Bailey RJ, Napoleone A.

Opt Lett. 1997 Oct 1;22(19):1479-81.


Regulation of survival signals from the insulin-like growth factor-I receptor.

O'Connor R, Fennelly C, Krause D.

Biochem Soc Trans. 2000 Feb;28(2):47-51. Review.


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