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Items: 1 to 20 of 45

1.

Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors.

Muk S, Ghosh S, Achuthan S, Chen X, Yao X, Sandhu M, Griffor MC, Fennell KF, Che Y, Shanmugasundaram V, Qiu X, Tate CG, Vaidehi N.

Biophys J. 2019 Dec 3;117(11):2228-2239. doi: 10.1016/j.bpj.2019.10.023. Epub 2019 Oct 24.

PMID:
31703801
2.

Epigenetic therapies in acute myeloid leukemia: where to from here?

Fennell KA, Bell CC, Dawson MA.

Blood. 2019 Nov 28;134(22):1891-1901. doi: 10.1182/blood.2019003262.

PMID:
31697822
3.

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

Bell CC, Fennell KA, Chan YC, Rambow F, Yeung MM, Vassiliadis D, Lara L, Yeh P, Martelotto LG, Rogiers A, Kremer BE, Barbash O, Mohammad HP, Johanson TM, Burr ML, Dhar A, Karpinich N, Tian L, Tyler DS, MacPherson L, Shi J, Pinnawala N, Yew Fong C, Papenfuss AT, Grimmond SM, Dawson SJ, Allan RS, Kruger RG, Vakoc CR, Goode DL, Naik SH, Gilan O, Lam EYN, Marine JC, Prinjha RK, Dawson MA.

Nat Commun. 2019 Jun 20;10(1):2723. doi: 10.1038/s41467-019-10652-9.

4.

A GYPB variant encoding an altered leader peptide leads to a weak S phenotype.

Cote J, Cen S, Fennell K, Pambrun C, Branch DR, Ochoa-Garay G.

Transfusion. 2019 Jul;59(7):2461-2462. doi: 10.1111/trf.15295. Epub 2019 Mar 30. No abstract available.

PMID:
30927367
5.

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.

Schnute ME, Wennerstål M, Alley J, Bengtsson M, Blinn JR, Bolten CW, Braden T, Bonn T, Carlsson B, Caspers N, Chen M, Choi C, Collis LP, Crouse K, Färnegårdh M, Fennell KF, Fish S, Flick AC, Goos-Nilsson A, Gullberg H, Harris PK, Heasley SE, Hegen M, Hromockyj AE, Hu X, Husman B, Janosik T, Jones P, Kaila N, Kallin E, Kauppi B, Kiefer JR, Knafels J, Koehler K, Kruger L, Kurumbail RG, Kyne RE Jr, Li W, Löfstedt J, Long SA, Menard CA, Mente S, Messing D, Meyers MJ, Napierata L, Nöteberg D, Nuhant P, Pelc MJ, Prinsen MJ, Rhönnstad P, Backström-Rydin E, Sandberg J, Sandström M, Shah F, Sjöberg M, Sundell A, Taylor AP, Thorarensen A, Trujillo JI, Trzupek JD, Unwalla R, Vajdos FF, Weinberg RA, Wood DC, Xing L, Zamaratski E, Zapf CW, Zhao Y, Wilhelmsson A, Berstein G.

J Med Chem. 2018 Dec 13;61(23):10415-10439. doi: 10.1021/acs.jmedchem.8b00392. Epub 2018 Sep 9.

PMID:
30130103
6.
7.

A telephone outcall program to support caregivers of people diagnosed with cancer: utility, changes in levels of distress, and unmet needs.

Heckel L, Fennell KM, Orellana L, Boltong A, Byrnes M, Livingston PM.

Support Care Cancer. 2018 Nov;26(11):3789-3799. doi: 10.1007/s00520-018-4246-6. Epub 2018 May 15.

PMID:
29766259
8.

Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.

Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fennell KF, Forman MD, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Kang Z, Kleiman RJ, Kormos BL, LaChapelle EA, Lee CW, Lu J, Maklad N, McDowell L, Mente S, O'Connor RE, Pandit J, Piotrowski M, Schmidt AW, Schmidt CJ, Ueno H, Verhoest PR, Yang EX.

J Med Chem. 2018 Apr 26;61(8):3753. doi: 10.1021/acs.jmedchem.8b00475. Epub 2018 Apr 6. No abstract available.

PMID:
29624389
9.

A comparison of barriers to accessing services for mental and physical health conditions in a sample of rural Australian adults.

Fennell K, Hull M, Jones M, Dollman J.

Rural Remote Health. 2018 Feb;18(1):4155. doi: 10.22605/RRH4155. Epub 2018 Feb 15.

10.

Efficacy of a telephone outcall program to reduce caregiver burden among caregivers of cancer patients [PROTECT]: a randomised controlled trial.

Heckel L, Fennell KM, Reynolds J, Boltong A, Botti M, Osborne RH, Mihalopoulos C, Chirgwin J, Williams M, Gaskin CJ, Ashley DM, Livingston PM.

BMC Cancer. 2018 Jan 8;18(1):59. doi: 10.1186/s12885-017-3961-6.

11.

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

Butler CR, Beck EM, Harris A, Huang Z, McAllister LA, Am Ende CW, Fennell K, Foley TL, Fonseca K, Hawrylik SJ, Johnson DS, Knafels JD, Mente S, Noell GS, Pandit J, Phillips TB, Piro JR, Rogers BN, Samad TA, Wang J, Wan S, Brodney MA.

J Med Chem. 2017 Dec 14;60(23):9860-9873. doi: 10.1021/acs.jmedchem.7b01531. Epub 2017 Dec 5.

PMID:
29148769
12.

SPOP tips the balance of BETs in cancer.

Fennell KA, Dawson MA.

Nat Med. 2017 Sep 8;23(9):1014-1015. doi: 10.1038/nm.4398. No abstract available.

PMID:
28886001
13.

Effect on gene expression of three allelic variants in GATA motifs of ABO, RHD, and RHCE regulatory elements.

Fennell K, Hoffman R, Yoshida K, Iwamoto S, Govender L, Vather K, Sookraj A, Jentsch U, Pambrun C, McAuley C, Keller MA, Ochoa-Garay G.

Transfusion. 2017 Nov;57(11):2804-2808. doi: 10.1111/trf.14299. Epub 2017 Aug 16.

PMID:
28815618
14.

'We're completely back to normal, but I'd say it's a new normal': a qualitative exploration of adaptive functioning in rural families following a parental cancer diagnosis.

Garrard ED, Fennell KM, Wilson C.

Support Care Cancer. 2017 Nov;25(11):3561-3568. doi: 10.1007/s00520-017-3785-6. Epub 2017 Jun 21.

PMID:
28639096
15.

A comparison of barriers to mental health support-seeking among farming and non-farming adults in rural South Australia.

Hull MJ, Fennell KM, Vallury K, Jones M, Dollman J.

Aust J Rural Health. 2017 Dec;25(6):347-353. doi: 10.1111/ajr.12352. Epub 2017 Jun 15.

PMID:
28618088
16.

Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.

Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fennell KF, Forman MD, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Kang Z, Kleiman RJ, Kormos BL, Lee CW, Lu J, Maklad N, McDowell L, Mente S, O'Connor RE, Pandit J, Piotrowski M, Schmidt AW, Schmidt CJ, Ueno H, Verhoest PR, Yang EX.

J Med Chem. 2017 Jul 13;60(13):5673-5698. doi: 10.1021/acs.jmedchem.7b00397. Epub 2017 Jun 16. Erratum in: J Med Chem. 2018 Apr 26;61(8):3753.

PMID:
28574706
17.

Demographic characteristics, call details and psychosocial support needs of the family/friends of someone diagnosed with cancer who access Australian Cancer Council telephone information and support services.

Heckel L, Fennell KM, Mohebbi M, Byrnes M, Livingston PM.

Eur J Oncol Nurs. 2017 Jun;28:86-91. doi: 10.1016/j.ejon.2017.03.007. Epub 2017 Apr 6.

PMID:
28478861
18.

Barriers to Seeking Help for Skin Cancer Detection in Rural Australia.

Fennell KM, Martin K, Wilson CJ, Trenerry C, Sharplin G, Dollman J.

J Clin Med. 2017 Feb 13;6(2). pii: E19. doi: 10.3390/jcm6020019.

19.

Use of the Distress Thermometer in a cancer helpline context: Can it detect changes in distress, is it acceptable to nurses and callers, and do high scores lead to internal referrals?

Linehan K, Fennell KM, Hughes DL, Wilson CJ.

Eur J Oncol Nurs. 2017 Feb;26:49-55. doi: 10.1016/j.ejon.2016.12.005. Epub 2016 Dec 21.

PMID:
28069152
20.

The information needs of adult cancer survivors across the cancer continuum: A scoping review.

Fletcher C, Flight I, Chapman J, Fennell K, Wilson C.

Patient Educ Couns. 2017 Mar;100(3):383-410. doi: 10.1016/j.pec.2016.10.008. Epub 2016 Oct 12. Review.

PMID:
27765377

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