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Items: 1 to 50 of 374

1.

Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9.

Secker KA, Keppeler H, Duerr-Stoerzer S, Schmid H, Schneidawind D, Hentrich T, Schulze-Hentrich JM, Mankel B, Fend F, Schneidawind C.

Oncogene. 2019 Aug 15. doi: 10.1038/s41388-019-0937-9. [Epub ahead of print]

PMID:
31417187
2.

The time to relapse correlates with the histopathological growth pattern in nodular lymphocyte predominant Hodgkin lymphoma.

Hartmann S, Plütschow A, Mottok A, Bernd HW, Feller AC, Ott G, Cogliatti S, Fend F, Quintanilla-Martinez L, Stein H, Klapper W, Möller P, Rosenwald A, Engert A, Hansmann ML, Eichenauer DA.

Am J Hematol. 2019 Aug 8. doi: 10.1002/ajh.25607. [Epub ahead of print]

PMID:
31396979
3.

Clonally related duodenal-type follicular lymphoma and in situ follicular neoplasia.

Nann D, Bonzheim I, Müller I, Mankel B, Quintanilla-Martínez L, Sipos B, Fend F.

Haematologica. 2019 Aug 1. pii: haematol.2019.226142. doi: 10.3324/haematol.2019.226142. [Epub ahead of print]

4.

Clonal evolution of chronic lymphocytic leukemia to Langerhans cell histiocytosis: a case report.

Frauenfeld L, Bonzheim I, Wirths S, Steinhilber J, Horger M, Mankel B, Bethge W, Fend F, Federmann B.

Virchows Arch. 2019 Jul 17. doi: 10.1007/s00428-019-02608-7. [Epub ahead of print]

PMID:
31317311
5.

Highly sensitive and specific in situ hybridization assay for quantification of SOX11 mRNA in mantle cell lymphoma reveals association of TP53 mutations with negative and low SOX11 expression.

Federmann B, Frauenfeld L, Pertsch H, Borgmann V, Steinhilber J, Bonzheim I, Fend F, Quintanilla-Martinez L.

Haematologica. 2019 Jul 11. pii: haematol.2019.219543. doi: 10.3324/haematol.2019.219543. [Epub ahead of print]

6.

Peripheral T-cell lymphoma NOS arising in patients with classical Hodgkin lymphoma of cytotoxic phenotype.

Huettl KS, Staiger AM, Stehle A, Bonzheim I, Horn H, Borgmann V, Ott M, Fend F, Ott G.

Leuk Lymphoma. 2019 Jul 10:1-4. doi: 10.1080/10428194.2019.1636987. [Epub ahead of print] No abstract available.

PMID:
31290373
7.

Genetic Testing in the Diagnosis and Biology of Myeloid Neoplasms (Excluding Acute Leukemias).

Hasserjian RP, Kelley TW, Weinberg OK, Morgan EA, Fend F.

Am J Clin Pathol. 2019 Aug 1;152(3):302-321. doi: 10.1093/ajcp/aqz069.

PMID:
31263893
8.

Deciphering hydroa vacciniforme.

Quintanilla-Martinez L, Fend F.

Blood. 2019 Jun 27;133(26):2735-2737. doi: 10.1182/blood.2019001031. No abstract available.

PMID:
31248873
9.

Oncological outcome of carcinomas in the rectosigmoid junction compared to the upper rectum or sigmoid colon - A retrospective cohort study.

Falch C, Mueller S, Braun M, Gani C, Fend F, Koenigsrainer A, Kirschniak A.

Eur J Surg Oncol. 2019 Jun 18. pii: S0748-7983(19)30518-9. doi: 10.1016/j.ejso.2019.06.024. [Epub ahead of print]

PMID:
31239157
10.

Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS.

Scheijen B, Meijers RWJ, Rijntjes J, van der Klift MY, Möbs M, Steinhilber J, Reigl T, van den Brand M, Kotrová M, Ritter JM, Catherwood MA, Stamatopoulos K, Brüggemann M, Davi F, Darzentas N, Pott C, Fend F, Hummel M, Langerak AW, Groenen PJTA; EuroClonality-NGS Working Group.

Leukemia. 2019 Jun 13. doi: 10.1038/s41375-019-0508-7. [Epub ahead of print]

PMID:
31197258
11.

Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.

Löffler MW, Mohr C, Bichmann L, Freudenmann LK, Walzer M, Schroeder CM, Trautwein N, Hilke FJ, Zinser RS, Mühlenbruch L, Kowalewski DJ, Schuster H, Sturm M, Matthes J, Riess O, Czemmel S, Nahnsen S, Königsrainer I, Thiel K, Nadalin S, Beckert S, Bösmüller H, Fend F, Velic A, Maček B, Haen SP, Buonaguro L, Kohlbacher O, Stevanović S, Königsrainer A; HEPAVAC Consortium, Rammensee HG.

Genome Med. 2019 Apr 30;11(1):28. doi: 10.1186/s13073-019-0636-8.

12.

Variant classification in precision oncology.

Leichsenring J, Horak P, Kreutzfeldt S, Heining C, Christopoulos P, Volckmar AL, Neumann O, Kirchner M, Ploeger C, Budczies J, Heilig CE, Hutter B, Fröhlich M, Uhrig S, Kazdal D, Allgäuer M, Harms A, Rempel E, Lehmann U, Thomas M, Pfarr N, Azoitei N, Bonzheim I, Marienfeld R, Möller P, Werner M, Fend F, Boerries M, von Bubnoff N, Lassmann S, Longerich T, Bitzer M, Seufferlein T, Malek N, Weichert W, Schirmacher P, Penzel R, Endris V, Brors B, Klauschen F, Glimm H, Fröhling S, Stenzinger A.

Int J Cancer. 2019 Apr 22. doi: 10.1002/ijc.32358. [Epub ahead of print]

PMID:
31008532
13.

Assessment of concomitant non-oncologic medication in patients with surgically treated renal cell carcinoma: impact on prognosis, cell-cycle progression and proliferation.

Neumann E, Klaiber P, Freitag K, Schwab M, Schaeffeler E, Hennenlotter J, Fend F, Kruck S, Scharpf M, Stenzl A, Bedke J, Rausch S.

J Cancer Res Clin Oncol. 2019 Jul;145(7):1835-1843. doi: 10.1007/s00432-019-02914-2. Epub 2019 Apr 22.

PMID:
31006846
14.

The pathological features of angioimmunoblastic T-cell lymphomas with IDH2R172 mutations.

Steinhilber J, Mederake M, Bonzheim I, Serinsöz-Linke E, Müller I, Fallier-Becker P, Lemonnier F, Gaulard P, Fend F, Quintanilla-Martinez L.

Mod Pathol. 2019 Jul;32(8):1123-1134. doi: 10.1038/s41379-019-0254-4. Epub 2019 Apr 5.

PMID:
30952970
15.

Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia.

Schittenhelm MM, Walter B, Tsintari V, Federmann B, Bajrami Saipi M, Akmut F, Illing B, Mau-Holzmann U, Fend F, Lopez CD, Kampa-Schittenhelm KM.

EBioMedicine. 2019 Apr;42:340-351. doi: 10.1016/j.ebiom.2019.03.028. Epub 2019 Apr 2.

16.

Epstein-Barr Virus-Associated T and NK-Cell Lymphoproliferative Diseases.

Kim WY, Montes-Mojarro IA, Fend F, Quintanilla-Martinez L.

Front Pediatr. 2019 Mar 15;7:71. doi: 10.3389/fped.2019.00071. eCollection 2019. Review.

17.

Pediatric Langerhans cell histiocytosis: the impact of mutational profile on clinical progression and late sequelae.

Nann D, Schneckenburger P, Steinhilber J, Metzler G, Beschorner R, Schwarze CP, Lang P, Handgretinger R, Fend F, Ebinger M, Bonzheim I.

Ann Hematol. 2019 Jul;98(7):1617-1626. doi: 10.1007/s00277-019-03678-y. Epub 2019 Mar 28.

PMID:
30923995
18.

Screening and evaluation of potential recipients and donors for living donor uterus transplantation: results from a single-center observational study.

Taran FA, Schöller D, Rall K, Nadalin S, Königsrainer A, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Grasshoff C, Heim E, Zipfel S, Schäffeler N, Bakchoul T, Heyne N, Guthoff M, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Brännström M, Wallwiener D, Brucker SY.

Fertil Steril. 2019 Jan;111(1):186-193. doi: 10.1016/j.fertnstert.2018.09.010.

PMID:
30611405
19.

CREBBP gene mutations are frequently detected in in situ follicular neoplasia.

Schmidt J, Ramis-Zaldivar JE, Bonzheim I, Steinhilber J, Müller I, Haake A, Yu SC, Raffeld M, Fend F, Salaverria I, Siebert R, Jaffe ES, Quintanilla-Martinez L.

Blood. 2018 Dec 20;132(25):2687-2690. doi: 10.1182/blood-2018-03-837039. Epub 2018 Nov 6. No abstract available.

PMID:
30401710
20.

[Report by the Haematopathology Working Group of the German Society of Pathology : Annual meeting 2018].

Fend F.

Pathologe. 2018 Dec;39(Suppl 2):328. doi: 10.1007/s00292-018-0537-4. German. No abstract available.

PMID:
30397785
21.

[Clonal evolution of early lymphoproliferations].

Fend F, Quintanilla-Martinez L.

Pathologe. 2018 Dec;39(Suppl 2):247-249. doi: 10.1007/s00292-018-0525-8. Review. German.

PMID:
30377786
22.

Cyclin D1-positive Mediastinal Large B-Cell Lymphoma With Copy Number Gains of CCND1 Gene: A Study of 3 Cases With Nonmediastinal Disease.

Chen BJ, Ruminy P, Roth CG, Bisig B, Mankel B, Steinhilber J, Bohers E, Jardin F, Fend F, Swerdlow SH, Copie-Bergman C, de Leval L, Quintanilla-Martinez L.

Am J Surg Pathol. 2019 Jan;43(1):110-120. doi: 10.1097/PAS.0000000000001154.

PMID:
30211726
23.

The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.

Gerst F, Jaghutriz BA, Staiger H, Schulte AM, Lorza-Gil E, Kaiser G, Panse M, Haug S, Heni M, Schütz M, Stadion M, Schürmann A, Marzetta F, Ibberson M, Sipos B, Fend F, Fleming T, Nawroth PP, Königsrainer A, Nadalin S, Wagner S, Peter A, Fritsche A, Richter D, Solimena M, Häring HU, Ullrich S, Wagner R.

J Clin Endocrinol Metab. 2018 Dec 1;103(12):4373-4383. doi: 10.1210/jc.2018-00791.

PMID:
30202879
24.

Characterization of the breast cancer resistance protein (BCRP/ABCG2) in clear cell renal cell carcinoma.

Reustle A, Fisel P, Renner O, Büttner F, Winter S, Rausch S, Kruck S, Nies AT, Hennenlotter J, Scharpf M, Fend F, Stenzl A, Bedke J, Schwab M, Schaeffeler E.

Int J Cancer. 2018 Dec 15;143(12):3181-3193. doi: 10.1002/ijc.31741. Epub 2018 Sep 25.

PMID:
30070687
25.

[Revised version of the 4th edition of the WHO classification of malignant lymphomas : What is new?]

Ott G, Klapper W, Feller AC, Hansmann ML, Möller P, Stein H, Rosenwald A, Fend F.

Pathologe. 2019 Mar;40(2):157-168. doi: 10.1007/s00292-018-0456-4. Review. German.

PMID:
30019203
26.

Langerhans cell histiocytosis associated with classical Hodgkin lymphoma contains BRAF V600E mutation.

Zhang S, Steinhilber J, Fend F.

Ann Hematol. 2019 Jan;98(1):231-233. doi: 10.1007/s00277-018-3425-3. Epub 2018 Jul 12. No abstract available.

PMID:
30003317
27.

Challenges in Diagnosing Myelodysplastic Syndromes in the Era of Genetic Testing: Proceedings of the 13th Workshop of the European Bone Marrow Working Group.

Hebeda KM, Tzankov A, Boudova L, Saft L, Hasserjian RP, de Boer M, Fend F, Orazi A, Leguit R.

Pathobiology. 2019;86(1):62-75. doi: 10.1159/000489678. Epub 2018 Jul 6.

28.

Clinical utility of the S3-score for molecular prediction of outcome in non-metastatic and metastatic clear cell renal cell carcinoma.

Büttner F, Winter S, Rausch S, Hennenlotter J, Kruck S, Stenzl A, Scharpf M, Fend F, Agaimy A, Hartmann A, Bedke J, Schwab M, Schaeffeler E.

BMC Med. 2018 Jul 5;16(1):108. doi: 10.1186/s12916-018-1088-5.

29.

Diagnosis of Richter transformation in chronic lymphocytic leukemia: histology tips the scales.

Federmann B, Mueller MR, Steinhilber J, Horger MS, Fend F.

Ann Hematol. 2018 Oct;97(10):1859-1868. doi: 10.1007/s00277-018-3390-x. Epub 2018 Jun 12.

PMID:
29947976
30.

Microvessel density and angiogenesis in primary hepatic malignancies: Differential expression of CD31 and VEGFR-2 in hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Bösmüller H, Pfefferle V, Bittar Z, Scheble V, Horger M, Sipos B, Fend F.

Pathol Res Pract. 2018 Aug;214(8):1136-1141. doi: 10.1016/j.prp.2018.06.011. Epub 2018 Jun 19.

PMID:
29935812
31.

Phase I Study of Oncolytic Vaccinia Virus GL-ONC1 in Patients with Peritoneal Carcinomatosis.

Lauer UM, Schell M, Beil J, Berchtold S, Koppenhöfer U, Glatzle J, Königsrainer A, Möhle R, Nann D, Fend F, Pfannenberg C, Bitzer M, Malek NP.

Clin Cancer Res. 2018 Sep 15;24(18):4388-4398. doi: 10.1158/1078-0432.CCR-18-0244. Epub 2018 May 17.

PMID:
29773661
32.

Spectral domain optical coherence tomography interpretation - Response to Blacklaws et al.

Fend F, Coupland S.

Br J Haematol. 2018 Jun;181(5):711. doi: 10.1111/bjh.15278. Epub 2018 May 16. No abstract available.

PMID:
29767429
33.

Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining.

Reinke S, Richter J, Fend F, Feller A, Hansmann ML, Hüttl K, Oschlies I, Ott G, Möller P, Rosenwald A, Stein H, Altenbuchinger M, Spang R, Klapper W.

Virchows Arch. 2018 Sep;473(3):341-349. doi: 10.1007/s00428-018-2367-4. Epub 2018 May 5.

PMID:
29730836
34.
35.

[Aggressive B‑cell lymphomas : Recommendations from the German Panel of Reference Pathologists in the Competence Network on Malignant Lymphomas on diagnostic procedures according to the current WHO classification, update 2017].

Klapper W, Fend F, Feller A, Hansmann ML, Möller P, Stein H, Rosenwald A, Ott G.

Pathologe. 2019 Mar;40(2):152-156. doi: 10.1007/s00292-018-0440-z. Review. German.

PMID:
29666909
36.

A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.

Wilke CM, Braselmann H, Hess J, Klymenko SV, Chumak VV, Zakhartseva LM, Bakhanova EV, Walch AK, Selmansberger M, Samaga D, Weber P, Schneider L, Fend F, Bösmüller HC, Zitzelsberger H, Unger K.

Int J Cancer. 2018 Sep 15;143(6):1505-1515. doi: 10.1002/ijc.31533. Epub 2018 May 10.

PMID:
29663366
37.

The Pathological Spectrum of Systemic Anaplastic Large Cell Lymphoma (ALCL).

Montes-Mojarro IA, Steinhilber J, Bonzheim I, Quintanilla-Martinez L, Fend F.

Cancers (Basel). 2018 Apr 4;10(4). pii: E107. doi: 10.3390/cancers10040107. Review.

38.

SDF-1/CXCR4 expression in head and neck cancer and outcome after postoperative radiochemotherapy.

De-Colle C, Mönnich D, Welz S, Boeke S, Sipos B, Fend F, Mauz PS, Tinhofer I, Budach V, Jawad JA, Stuschke M, Balermpas P, Rödel C, Grosu AL, Abdollahi A, Debus J, Bayer C, Belka C, Pigorsch S, Combs SE, Lohaus F, Linge A, Krause M, Baumann M, Zips D, Menegakis A.

Clin Transl Radiat Oncol. 2017 Jul 14;5:28-36. doi: 10.1016/j.ctro.2017.06.004. eCollection 2017 Aug.

39.

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia.

Kampa-Schittenhelm KM, Vogel W, Bonzheim I, Fend F, Horger M, Kanz L, Soekler M, Schittenhelm MM.

Oncotarget. 2018 Jan 31;9(14):11876-11882. doi: 10.18632/oncotarget.24376. eCollection 2018 Feb 20.

40.

EBV-Positive Lymphoproliferations of B- T- and NK-Cell Derivation in Non-Immunocompromised Hosts.

Dojcinov SD, Fend F, Quintanilla-Martinez L.

Pathogens. 2018 Mar 7;7(1). pii: E28. doi: 10.3390/pathogens7010028. Review.

41.

Metabolic and Lipidomic Reprogramming in Renal Cell Carcinoma Subtypes Reflects Regions of Tumor Origin.

Schaeffeler E, Büttner F, Reustle A, Klumpp V, Winter S, Rausch S, Fisel P, Hennenlotter J, Kruck S, Stenzl A, Wahrheit J, Sonntag D, Scharpf M, Fend F, Agaimy A, Hartmann A, Bedke J, Schwab M.

Eur Urol Focus. 2018 Feb 13. pii: S2405-4569(18)30017-8. doi: 10.1016/j.euf.2018.01.016. [Epub ahead of print]

PMID:
29452772
42.

Multicenter validation of cancer gene panel-based next-generation sequencing for translational research and molecular diagnostics.

Hirsch B, Endris V, Lassmann S, Weichert W, Pfarr N, Schirmacher P, Kovaleva V, Werner M, Bonzheim I, Fend F, Sperveslage J, Kaulich K, Zacher A, Reifenberger G, Köhrer K, Stepanow S, Lerke S, Mayr T, Aust DE, Baretton G, Weidner S, Jung A, Kirchner T, Hansmann ML, Burbat L, von der Wall E, Dietel M, Hummel M.

Virchows Arch. 2018 Apr;472(4):557-565. doi: 10.1007/s00428-017-2288-7. Epub 2018 Jan 27.

43.

A prospective randomized experimental study to investigate the peritoneal adhesion formation after waterjet injection and argon plasma coagulation (HybridAPC) in a rat model.

Kraemer B, Scharpf M, Keckstein S, Dippon J, Tsaousidis C, Brunecker K, Enderle MD, Neugebauer A, Nuessle D, Fend F, Brucker S, Taran FA, Kommoss S, Rothmund R.

Arch Gynecol Obstet. 2018 Apr;297(4):961-967. doi: 10.1007/s00404-018-4661-4. Epub 2018 Jan 23.

PMID:
29362925
44.

Selecting living donors for uterus transplantation: lessons learned from two transplantations resulting in menstrual functionality and another attempt, aborted after organ retrieval.

Brucker SY, Brännström M, Taran FA, Nadalin S, Königsrainer A, Rall K, Schöller D, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Rosenberger P, Grasshoff C, Heim E, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Dahm-Kähler P, Kvarnström N, Wallwiener D.

Arch Gynecol Obstet. 2018 Mar;297(3):675-684. doi: 10.1007/s00404-017-4626-z. Epub 2017 Dec 21.

PMID:
29270725
45.

Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder.

Vollmer JP, Haen S, Wolburg H, Lehmann R, Steiner J, Reddersen S, Fend F, Fallier-Becker P.

Crit Care Med. 2018 Jan;46(1):e91-e94. doi: 10.1097/CCM.0000000000002802.

PMID:
29252954
46.

Androgen receptor overexpression in prostate cancer in type 2 diabetes.

Lutz SZ, Hennenlotter J, Scharpf MO, Sailer C, Fritsche L, Schmid V, Kantartzis K, Wagner R, Lehmann R, Berti L, Peter A, Staiger H, Fritsche A, Fend F, Todenhöfer T, Stenzl A, Häring HU, Heni M.

Mol Metab. 2018 Feb;8:158-166. doi: 10.1016/j.molmet.2017.11.013. Epub 2017 Dec 5.

47.

The immunopeptidomic landscape of ovarian carcinomas.

Schuster H, Peper JK, Bösmüller HC, Röhle K, Backert L, Bilich T, Ney B, Löffler MW, Kowalewski DJ, Trautwein N, Rabsteyn A, Engler T, Braun S, Haen SP, Walz JS, Schmid-Horch B, Brucker SY, Wallwiener D, Kohlbacher O, Fend F, Rammensee HG, Stevanović S, Staebler A, Wagner P.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9942-E9951. doi: 10.1073/pnas.1707658114. Epub 2017 Nov 1.

48.

SDF-1/CXCR4 expression is an independent negative prognostic biomarker in patients with head and neck cancer after primary radiochemotherapy.

De-Colle C, Menegakis A, Mönnich D, Welz S, Boeke S, Sipos B, Fend F, Mauz PS, Tinhofer I, Budach V, Abu Jawad J, Stuschke M, Balermpas P, Rödel C, Grosu AL, Abdollahi A, Debus J, Belka C, Ganswindt U, Pigorsch S, Combs SE, Lohaus F, Linge A, Krause M, Baumann M, Zips D; DKTK-ROG.

Radiother Oncol. 2018 Jan;126(1):125-131. doi: 10.1016/j.radonc.2017.10.008. Epub 2017 Oct 20.

PMID:
29061496
49.

[Malignant lymphomas of the eye].

Fend F, Süsskind D, Deuter C, Coupland SE.

Pathologe. 2017 Nov;38(6):515-520. doi: 10.1007/s00292-017-0378-6. Review. German.

PMID:
28993856
50.

[Tumors of the sensory organs].

Fend F.

Pathologe. 2017 Nov;38(6):490. doi: 10.1007/s00292-017-0386-6. German. No abstract available.

PMID:
28993830

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