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Items: 1 to 50 of 70

1.

Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics.

Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB.

Viruses. 2020 Jan 15;12(1). pii: E103. doi: 10.3390/v12010103.

2.

The Cross-Modal Effects of Sensory Deprivation on Spatial and Temporal Processes in Vision and Audition: A Systematic Review on Behavioral and Neuroimaging Research since 2000.

Bell L, Wagels L, Neuschaefer-Rube C, Fels J, Gur RE, Konrad K.

Neural Plast. 2019 Dec 2;2019:9603469. doi: 10.1155/2019/9603469. eCollection 2019. Review.

3.

UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia.

Zouhar P, Rakipovski G, Bokhari MH, Busby O, Paulsson JF, Conde-Frieboes KW, Fels JJ, Raun K, Andersen B, Cannon B, Nedergaard J.

Am J Physiol Endocrinol Metab. 2020 Jan 1;318(1):E72-E86. doi: 10.1152/ajpendo.00253.2019. Epub 2019 Nov 19.

4.

Importance of gestational hypoglycaemia for foetal malformations and skeletal development in rats.

Jensen VFH, Mølck AM, Lykkesfeldt J, Fels JJ, Andersen L, Renaut R, McGuigan F, Åkesson KE, Bøgh IB.

Reprod Toxicol. 2020 Jan;91:14-26. doi: 10.1016/j.reprotox.2019.10.003. Epub 2019 Oct 20.

PMID:
31644949
5.

The Contribution of Individual Differences in Memory Span and Language Ability to Spatial Release From Masking in Young Children.

MacCutcheon D, Pausch F, Füllgrabe C, Eccles R, van der Linde J, Panebianco C, Fels J, Ljung R.

J Speech Lang Hear Res. 2019 Oct 25;62(10):3741-3751. doi: 10.1044/2019_JSLHR-S-19-0012. Epub 2019 Oct 17.

PMID:
31619115
6.

A luminal unfolding microneedle injector for oral delivery of macromolecules.

Abramson A, Caffarel-Salvador E, Soares V, Minahan D, Tian RY, Lu X, Dellal D, Gao Y, Kim S, Wainer J, Collins J, Tamang S, Hayward A, Yoshitake T, Lee HC, Fujimoto J, Fels J, Frederiksen MR, Rahbek U, Roxhed N, Langer R, Traverso G.

Nat Med. 2019 Oct;25(10):1512-1518. doi: 10.1038/s41591-019-0598-9. Epub 2019 Oct 7.

PMID:
31591601
7.

Soluble adenylyl cyclase (sAC) regulates calcium signaling in the vascular endothelium.

Mewes M, Lenders M, Stappers F, Scharnetzki D, Nedele J, Fels J, Wedlich-Söldner R, Brand SM, Schmitz B, Brand E.

FASEB J. 2019 Dec;33(12):13762-13774. doi: 10.1096/fj.201900724R. Epub 2019 Oct 4.

PMID:
31585052
8.

Spatial Release From Masking Under Different Reverberant Conditions in Young and Elderly Subjects: Effect of Moving or Stationary Maskers at Circular and Radial Conditions.

Muñoz RV, Aspöck L, Fels J.

J Speech Lang Hear Res. 2019 Sep 20;62(9):3582-3595. doi: 10.1044/2019_JSLHR-H-19-0092. Epub 2019 Sep 16.

PMID:
31525113
9.

TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in zebrafish.

Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B.

Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241.

10.

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry.

Fels JM, Spence JS, Bortz RH 3rd, Bornholdt ZA, Chandran K.

mBio. 2019 Jul 9;10(4). pii: e01408-19. doi: 10.1128/mBio.01408-19.

11.

Long-acting CCK analogue NN9056 lowers food intake and body weight in obese Göttingen Minipigs.

Christoffersen BØ, Skyggebjerg RB, Bugge A, Kirk RK, Vestergaard B, Uldam HK, Fels JJ, Pyke C, Sensfuss U, Sanfridson A, Clausen TR.

Int J Obes (Lond). 2019 Jun 7. doi: 10.1038/s41366-019-0386-0. [Epub ahead of print]

PMID:
31175319
12.

Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule.

Fels J, Scharner B, Zarbock R, Zavala Guevara IP, Lee WK, Barbier OC, Thévenod F.

Int J Mol Sci. 2019 May 14;20(10). pii: E2379. doi: 10.3390/ijms20102379.

13.

Sex Differences in Ischemia/Reperfusion Injury: The Role of Mitochondrial Permeability Transition.

Fels JA, Manfredi G.

Neurochem Res. 2019 Oct;44(10):2336-2345. doi: 10.1007/s11064-019-02769-6. Epub 2019 Mar 12.

PMID:
30863968
14.

An ingestible self-orienting system for oral delivery of macromolecules.

Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, Tamang S, Hayward A, Landh T, Buckley ST, Roxhed N, Rahbek U, Langer R, Traverso G.

Science. 2019 Feb 8;363(6427):611-615. doi: 10.1126/science.aau2277.

PMID:
30733413
15.

Channels, transporters and receptors for cadmium and cadmium complexes in eukaryotic cells: myths and facts.

Thévenod F, Fels J, Lee WK, Zarbock R.

Biometals. 2019 Jun;32(3):469-489. doi: 10.1007/s10534-019-00176-6. Epub 2019 Jan 30.

PMID:
30701379
16.

The binding of an auditory target location to a judgement: A two-component switching approach.

Seibold JC, Nolden S, Oberem J, Fels J, Koch I.

Q J Exp Psychol (Hove). 2019 Aug;72(8):2056-2067. doi: 10.1177/1747021819829422. Epub 2019 Feb 15.

PMID:
30672384
17.

Palliative care in everyday practice of radiation oncologists : Results from a web-based survey among medical members of the German Society for Radiation Oncology (DEGRO).

Fels J, Pigorsch S, Vorwerk H, Engenhart-Cabillic R, van Oorschot B.

Strahlenther Onkol. 2019 Jul;195(7):659-667. doi: 10.1007/s00066-018-1403-2. Epub 2018 Nov 29.

PMID:
30498845
18.

Protocadherin-1 is essential for cell entry by New World hantaviruses.

Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, Ng M, Mittler E, Pan J, Bharrhan S, Wec AZ, Lai JR, Sidhu SS, Tischler ND, Rey FA, Moffat J, Brummelkamp TR, Wang Z, Dye JM, Chandran K.

Nature. 2018 Nov;563(7732):559-563. doi: 10.1038/s41586-018-0702-1. Epub 2018 Nov 21.

19.

The Effect of Diet-induced Obesity on Toxicological Parameters in the Polygenic Sprague-Dawley Rat Model.

Rojas JM, Bolze F, Thorup I, Nowak J, Dalsgaard CM, Skydsgaard M, Berthelsen LO, Keane KA, Søeborg H, Sjögren I, Jensen JT, Fels JJ, Offenberg HK, Andersen LW, Dalgaard M.

Toxicol Pathol. 2018 Oct;46(7):777-798. doi: 10.1177/0192623318803557. Epub 2018 Oct 22.

PMID:
30343647
20.

FGF21 decreases food intake and body weight in obese Göttingen minipigs.

Christoffersen B, Straarup EM, Lykkegaard K, Fels JJ, Sass-Ørum K, Zhang X, Raun K, Andersen B.

Diabetes Obes Metab. 2019 Mar;21(3):592-600. doi: 10.1111/dom.13560. Epub 2018 Nov 20.

PMID:
30328263
21.

An Extended Binaural Real-Time Auralization System With an Interface to Research Hearing Aids for Experiments on Subjects With Hearing Loss.

Pausch F, Aspöck L, Vorländer M, Fels J.

Trends Hear. 2018 Jan-Dec;22:2331216518800871. doi: 10.1177/2331216518800871. Review.

22.

Long-Acting Human Growth Hormone Analogue by Noncovalent Albumin Binding.

Ramírez-Andersen HS, Behrens C, Buchardt J, Fels JJ, Folkesson CG, Jianhe C, Nørskov-Lauritsen L, Nielsen PF, Reslow M, Rischel C, Su J, Thygesen P, Wiberg C, Zhao X, Wenjuan X, Johansen NL.

Bioconjug Chem. 2018 Sep 19;29(9):3129-3143. doi: 10.1021/acs.bioconjchem.8b00463. Epub 2018 Aug 31.

PMID:
30168709
23.

The effect of language, spatial factors, masker type and memory span on speech-in-noise thresholds in sequential bilingual children.

MacCutcheon D, Pausch F, Fels J, Ljung R.

Scand J Psychol. 2018 Dec;59(6):567-577. doi: 10.1111/sjop.12466. Epub 2018 Aug 23.

PMID:
30137681
24.

Auditory attention switching and judgment switching: Exploring multicomponent task representations.

Seibold JC, Nolden S, Oberem J, Fels J, Koch I.

Atten Percept Psychophys. 2018 Oct;80(7):1823-1832. doi: 10.3758/s13414-018-1557-0.

PMID:
29959662
25.

Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.

Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DA.

Neurobiol Learn Mem. 2018 Oct;154:141-157. doi: 10.1016/j.nlm.2018.06.004. Epub 2018 Jun 12.

26.

A two-phase response of endothelial cells to hydrostatic pressure.

Prystopiuk V, Fels B, Simon CS, Liashkovich I, Pasrednik D, Kronlage C, Wedlich-Söldner R, Oberleithner H, Fels J.

J Cell Sci. 2018 Jun 21;131(12). pii: jcs206920. doi: 10.1242/jcs.206920.

27.

NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations.

Gupta SK, Wesolowska-Andersen A, Ringgaard AK, Jaiswal H, Song L, Hastoy B, Ingvorsen C, Taheri-Ghahfarokhi A, Magnusson B, Maresca M, Jensen RR, Beer NL, Fels JJ, Grunnet LG, Thomas MK, Gloyn AL, Hicks R, McCarthy MI, Hansson M, Honoré C.

Stem Cell Res. 2018 May;29:220-231. doi: 10.1016/j.scr.2018.04.010. Epub 2018 Apr 23.

28.

Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics.

Rune I, Rolin B, Lykkesfeldt J, Nielsen DS, Krych Ł, Kanter JE, Bornfeldt KE, Kihl P, Buschard K, Josefsen K, Fels JJ, Mortensen A, Christoffersen B, Kirk RK, Hansen AK.

Sci Rep. 2018 Apr 3;8(1):5416. doi: 10.1038/s41598-018-23835-z.

29.

Estrogen receptor beta modulates permeability transition in brain mitochondria.

Burstein SR, Kim HJ, Fels JA, Qian L, Zhang S, Zhou P, Starkov AA, Iadecola C, Manfredi G.

Biochim Biophys Acta Bioenerg. 2018 Jun;1859(6):423-433. doi: 10.1016/j.bbabio.2018.03.006. Epub 2018 Mar 14.

30.

Endothelial Nanomechanics in the Context of Endothelial (Dys)function and Inflammation.

Fels J, Kusche-Vihrog K.

Antioxid Redox Signal. 2019 Mar 1;30(7):945-959. doi: 10.1089/ars.2017.7327. Epub 2018 Mar 22.

31.

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.

Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, Öberg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Grønborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honoré C, Ahnfelt-Rønne J, Hecksher-Sørensen J, Ravassard P, Madsen OD, Rescan C, Frogne T.

Mol Metab. 2018 Feb;8:144-157. doi: 10.1016/j.molmet.2017.12.007. Epub 2017 Dec 19.

32.

Intentional switching in auditory selective attention: Exploring attention shifts with different reverberation times.

Oberem J, Seibold J, Koch I, Fels J.

Hear Res. 2018 Mar;359:32-39. doi: 10.1016/j.heares.2017.12.013. Epub 2017 Dec 22.

PMID:
29305038
33.

Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes.

An D, Chiu A, Flanders JA, Song W, Shou D, Lu YC, Grunnet LG, Winkel L, Ingvorsen C, Christophersen NS, Fels JJ, Sand FW, Ji Y, Qi L, Pardo Y, Luo D, Silberstein M, Fan J, Ma M.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E263-E272. doi: 10.1073/pnas.1708806115. Epub 2017 Dec 26.

34.

Intentional preparation of auditory attention-switches: Explicit cueing and sequential switch-predictability.

Seibold JC, Nolden S, Oberem J, Fels J, Koch I.

Q J Exp Psychol (Hove). 2018 Jun;71(6):1382-1395. doi: 10.1080/17470218.2017.1344867. Epub 2018 Jan 1. Erratum in: Q J Exp Psychol (Hove). 2019 Mar;72(3):675-676.

PMID:
28631530
35.

Nonclinical pharmacokinetic and pharmacodynamic characterisation of somapacitan: A reversible non-covalent albumin-binding growth hormone.

Thygesen P, Andersen HS, Behrens C, Fels JJ, Nørskov-Lauritsen L, Rischel C, Johansen NL.

Growth Horm IGF Res. 2017 Aug;35:8-16. doi: 10.1016/j.ghir.2017.05.006. Epub 2017 May 24.

PMID:
28595133
36.

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.

Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang CI, Lei L, Fels JM, Vu H, Shulenin S, Turonis AN, Kuehne AI, Liu G, Ta M, Wang Y, Sundling C, Xiao Y, Spence JS, Doranz BJ, Holtsberg FW, Ward AB, Chandran K, Dye JM, Qiu X, Li Y, Aman MJ.

Cell. 2017 May 18;169(5):891-904.e15. doi: 10.1016/j.cell.2017.04.038.

37.

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

Wec AZ, Herbert AS, Murin CD, Nyakatura EK, Abelson DM, Fels JM, He S, James RM, de La Vega MA, Zhu W, Bakken RR, Goodwin E, Turner HL, Jangra RK, Zeitlin L, Qiu X, Lai JR, Walker LM, Ward AB, Dye JM, Chandran K, Bornholdt ZA.

Cell. 2017 May 18;169(5):878-890.e15. doi: 10.1016/j.cell.2017.04.037.

38.

Intentional switching in auditory selective attention: Exploring age-related effects in a spatial setup requiring speech perception.

Oberem J, Koch I, Fels J.

Acta Psychol (Amst). 2017 Jun;177:36-43. doi: 10.1016/j.actpsy.2017.04.008. Epub 2017 Apr 28.

PMID:
28456098
39.

Calcium-mediated actin reset (CaAR) mediates acute cell adaptations.

Wales P, Schuberth CE, Aufschnaiter R, Fels J, García-Aguilar I, Janning A, Dlugos CP, Schäfer-Herte M, Klingner C, Wälte M, Kuhlmann J, Menis E, Hockaday Kang L, Maier KC, Hou W, Russo A, Higgs HN, Pavenstädt H, Vogl T, Roth J, Qualmann B, Kessels MM, Martin DE, Mulder B, Wedlich-Söldner R.

Elife. 2016 Dec 6;5. pii: e19850. doi: 10.7554/eLife.19850.

40.

The kidneys play a central role in the clearance of rhGH in rats.

Vestergaard B, Thygesen P, Kreilgaard M, Fels JJ, Lykkesfeldt J, Agersø H.

Eur J Pharm Sci. 2016 Apr 30;86:29-33. doi: 10.1016/j.ejps.2016.02.019. Epub 2016 Mar 2.

PMID:
26946443
41.

Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice.

Rune I, Rolin B, Larsen C, Nielsen DS, Kanter JE, Bornfeldt KE, Lykkesfeldt J, Buschard K, Kirk RK, Christoffersen B, Fels JJ, Josefsen K, Kihl P, Hansen AK.

PLoS One. 2016 Jan 22;11(1):e0146439. doi: 10.1371/journal.pone.0146439. eCollection 2016.

42.

Feeling for Filaments: Quantification of the Cortical Actin Web in Live Vascular Endothelium.

Kronlage C, Schäfer-Herte M, Böning D, Oberleithner H, Fels J.

Biophys J. 2015 Aug 18;109(4):687-98. doi: 10.1016/j.bpj.2015.06.066.

43.

Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes.

Skovsø S, Damgaard J, Fels JJ, Olsen GS, Wolf XA, Rolin B, Holst JJ.

Int J Obes (Lond). 2015 Oct;39(10):1531-8. doi: 10.1038/ijo.2015.92. Epub 2015 May 26.

PMID:
26121961
44.

Evolving role of the transitional care nurse in a small rural community.

Fels J, Allard BL, Coppin K, Hewson K, Richardson B.

Home Healthc Now. 2015 Apr;33(4):215-21. doi: 10.1097/NHH.0000000000000219.

PMID:
25828613
45.

Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells.

Klingner C, Cherian AV, Fels J, Diesinger PM, Aufschnaiter R, Maghelli N, Keil T, Beck G, Tolić-Nørrelykke IM, Bathe M, Wedlich-Soldner R.

J Cell Biol. 2014 Oct 13;207(1):107-21. doi: 10.1083/jcb.201402037.

46.

Intentional attention switching in dichotic listening: exploring the efficiency of nonspatial and spatial selection.

Lawo V, Fels J, Oberem J, Koch I.

Q J Exp Psychol (Hove). 2014 Oct;67(10):2010-24. doi: 10.1080/17470218.2014.898079. Epub 2014 Mar 19.

PMID:
25248101
47.

Fixed endothelial cells exhibit physiologically relevant nanomechanics of the cortical actin web.

Grimm KB, Oberleithner H, Fels J.

Nanotechnology. 2014 May 30;25(21):215101. doi: 10.1088/0957-4484/25/21/215101. Epub 2014 May 2.

PMID:
24786855
48.

High fat, low carbohydrate diet limit fear and aggression in Göttingen minipigs.

Haagensen AM, Sørensen DB, Sandøe P, Matthews LR, Birck MM, Fels JJ, Astrup A.

PLoS One. 2014 Apr 16;9(4):e93821. doi: 10.1371/journal.pone.0093821. eCollection 2014.

49.

Nanomechanics of vascular endothelium.

Fels J, Jeggle P, Liashkovich I, Peters W, Oberleithner H.

Cell Tissue Res. 2014 Mar;355(3):727-37. doi: 10.1007/s00441-014-1853-5. Epub 2014 Mar 19. Review.

50.

The epithelial Na+ channel: a new player in the vasculature.

Kusche-Vihrog K, Tarjus A, Fels J, Jaisser F.

Curr Opin Nephrol Hypertens. 2014 Mar;23(2):143-8. doi: 10.1097/01.mnh.0000441054.88962.2c. Review.

PMID:
24378777

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