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Items: 1 to 50 of 96

1.

Stoichiometric analysis of the energetics and metabolic impact of photorespiration in C3 plants.

Huma B, Kundu S, Poolman MG, Kruger NJ, Fell DA.

Plant J. 2018 Dec;96(6):1228-1241. doi: 10.1111/tpj.14105. Epub 2018 Oct 20.

PMID:
30257035
2.

Genotype to phenotype mapping still needs underpinning by research in metabolism and enzymology.

Fell DA.

Biosci Rep. 2018 Jun 21;38(3). pii: BSR20180520. doi: 10.1042/BSR20180520. Print 2018 Jun 29.

3.

Model-assisted metabolic engineering of Escherichia coli for long chain alkane and alcohol production.

Fatma Z, Hartman H, Poolman MG, Fell DA, Srivastava S, Shakeel T, Yazdani SS.

Metab Eng. 2018 Mar;46:1-12. doi: 10.1016/j.ymben.2018.01.002. Epub 2018 Feb 3.

PMID:
29408291
4.

Model-based biotechnological potential analysis of Kluyveromyces marxianus central metabolism.

Pentjuss A, Stalidzans E, Liepins J, Kokina A, Martynova J, Zikmanis P, Mozga I, Scherbaka R, Hartman H, Poolman MG, Fell DA, Vigants A.

J Ind Microbiol Biotechnol. 2017 Aug;44(8):1177-1190. doi: 10.1007/s10295-017-1946-8. Epub 2017 Apr 25.

PMID:
28444480
5.

A Genome Scale Model of Geobacillus thermoglucosidasius (C56-YS93) reveals its biotechnological potential on rice straw hydrolysate.

Ahmad A, Hartman HB, Krishnakumar S, Fell DA, Poolman MG, Srivastava S.

J Biotechnol. 2017 Jun 10;251:30-37. doi: 10.1016/j.jbiotec.2017.03.031. Epub 2017 Apr 4.

PMID:
28385593
6.

Metabolic trade-offs between biomass synthesis and photosynthate export at different light intensities in a genome-scale metabolic model of rice.

Poolman MG, Kundu S, Shaw R, Fell DA.

Front Plant Sci. 2014 Nov 28;5:656. doi: 10.3389/fpls.2014.00656. eCollection 2014.

7.

Identification of potential drug targets in Salmonella enterica sv. Typhimurium using metabolic modelling and experimental validation.

Hartman HB, Fell DA, Rossell S, Jensen PR, Woodward MJ, Thorndahl L, Jelsbak L, Olsen JE, Raghunathan A, Daefler S, Poolman MG.

Microbiology. 2014 Jun;160(Pt 6):1252-1266. doi: 10.1099/mic.0.076091-0. Epub 2014 Apr 28.

PMID:
24777662
8.

A Diel Flux Balance Model Captures Interactions between Light and Dark Metabolism during Day-Night Cycles in C3 and Crassulacean Acid Metabolism Leaves.

Cheung CY, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2014 Jun;165(2):917-929. Epub 2014 Mar 4.

9.

Modeling of Zymomonas mobilis central metabolism for novel metabolic engineering strategies.

Kalnenieks U, Pentjuss A, Rutkis R, Stalidzans E, Fell DA.

Front Microbiol. 2014 Feb 5;5:42. doi: 10.3389/fmicb.2014.00042. eCollection 2014.

10.

Kinetic modelling of the Zymomonas mobilis Entner-Doudoroff pathway: insights into control and functionality.

Rutkis R, Kalnenieks U, Stalidzans E, Fell DA.

Microbiology. 2013 Dec;159(Pt 12):2674-89. doi: 10.1099/mic.0.071340-0. Epub 2013 Oct 1.

PMID:
24085837
11.

A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.

Cheung CY, Williams TC, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant J. 2013 Sep;75(6):1050-61. doi: 10.1111/tpj.12252. Epub 2013 Aug 6.

12.

Responses to light intensity in a genome-scale model of rice metabolism.

Poolman MG, Kundu S, Shaw R, Fell DA.

Plant Physiol. 2013 Jun;162(2):1060-72. doi: 10.1104/pp.113.216762. Epub 2013 May 2.

13.

Biotechnological potential of respiring Zymomonas mobilis: a stoichiometric analysis of its central metabolism.

Pentjuss A, Odzina I, Kostromins A, Fell DA, Stalidzans E, Kalnenieks U.

J Biotechnol. 2013 May 10;165(1):1-10. doi: 10.1016/j.jbiotec.2013.02.014. Epub 2013 Mar 5.

PMID:
23471074
14.

Building and analysing genome-scale metabolic models.

Fell DA, Poolman MG, Gevorgyan A.

Biochem Soc Trans. 2010 Oct;38(5):1197-201. doi: 10.1042/BST0381197.

PMID:
20863283
15.

Evolution of central carbon metabolism.

Fell DA.

Mol Cell. 2010 Sep 10;39(5):663-4. doi: 10.1016/j.molcel.2010.08.034.

16.

A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions.

Williams TC, Poolman MG, Howden AJ, Schwarzlander M, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2010 Sep;154(1):311-23. doi: 10.1104/pp.110.158535. Epub 2010 Jul 6.

17.

Response to comment on 'Can sugars be produced from fatty acids? A test case for pathway analysis tools'.

de Figueiredo LF, Schuster S, Kaleta C, Fell DA.

Bioinformatics. 2009 Dec 15;25(24):3330-1. doi: 10.1093/bioinformatics/btp591. Epub 2009 Oct 13. No abstract available.

PMID:
19825797
18.

A genome-scale metabolic model of Arabidopsis and some of its properties.

Poolman MG, Miguet L, Sweetlove LJ, Fell DA.

Plant Physiol. 2009 Nov;151(3):1570-81. doi: 10.1104/pp.109.141267. Epub 2009 Sep 15.

19.

Contribution of NADH increases to ethanol's inhibition of retinol oxidation by human ADH isoforms.

Chase JR, Poolman MG, Fell DA.

Alcohol Clin Exp Res. 2009 Apr;33(4):571-80. doi: 10.1111/j.1530-0277.2008.00871.x. Epub 2009 Jan 16.

20.

Can sugars be produced from fatty acids? A test case for pathway analysis tools.

de Figueiredo LF, Schuster S, Kaleta C, Fell DA.

Bioinformatics. 2009 Jan 1;25(1):152-8.

PMID:
19117076
21.

Can sugars be produced from fatty acids? A test case for pathway analysis tools.

de Figueiredo LF, Schuster S, Kaleta C, Fell DA.

Bioinformatics. 2008 Nov 15;24(22):2615-21. doi: 10.1093/bioinformatics/btn500. Epub 2008 Sep 19. Corrected and republished in: Bioinformatics. 2009 Jan 1;25(1):152-8.

PMID:
18806269
22.

Detection of stoichiometric inconsistencies in biomolecular models.

Gevorgyan A, Poolman MG, Fell DA.

Bioinformatics. 2008 Oct 1;24(19):2245-51. doi: 10.1093/bioinformatics/btn425. Epub 2008 Aug 12.

PMID:
18697772
23.

Is maximization of molar yield in metabolic networks favoured by evolution?

Schuster S, Pfeiffer T, Fell DA.

J Theor Biol. 2008 Jun 7;252(3):497-504. doi: 10.1016/j.jtbi.2007.12.008. Epub 2007 Dec 23.

PMID:
18249414
24.

Modular decomposition of metabolic systems via null-space analysis.

Poolman MG, Sebu C, Pidcock MK, Fell DA.

J Theor Biol. 2007 Dec 21;249(4):691-705. Epub 2007 Aug 19.

PMID:
17949756
25.

Systems biology meets chromatin function. Workshop on Nuclear Organization.

Visser AE, Fell DA.

EMBO Rep. 2007 May;8(5):446-50. Epub 2007 Apr 13. No abstract available.

26.

Challenges to be faced in the reconstruction of metabolic networks from public databases.

Poolman MG, Bonde BK, Gevorgyan A, Patel HH, Fell DA.

Syst Biol (Stevenage). 2006 Sep;153(5):379-84.

PMID:
16986322
27.

Using a mammalian cell cycle simulation to interpret differential kinase inhibition in anti-tumour pharmaceutical development.

Chassagnole C, Jackson RC, Hussain N, Bashir L, Derow C, Savin J, Fell DA.

Biosystems. 2006 Feb-Mar;83(2-3):91-7. Epub 2005 Oct 19.

PMID:
16236428
28.

Myocardial energy metabolism in ischemic preconditioning and cardioplegia: a metabolic control analysis.

Vogt AM, Elsässer A, Pott-Beckert A, Ackermann C, Vetter SY, Yildiz M, Schoels W, Fell DA, Katus HA, Kübler W.

Mol Cell Biochem. 2005 Oct;278(1-2):223-32.

PMID:
16180108
29.

Enzymes, metabolites and fluxes.

Fell DA.

J Exp Bot. 2005 Jan;56(410):267-72. Epub 2004 Nov 15. Review.

PMID:
15545297
30.

A method for the determination of flux in elementary modes, and its application to Lactobacillus rhamnosus.

Poolman MG, Venkatesh KV, Pidcock MK, Fell DA.

Biotechnol Bioeng. 2004 Dec 5;88(5):601-12.

PMID:
15470705
31.

Applications of metabolic modelling to plant metabolism.

Poolman MG, Assmus HE, Fell DA.

J Exp Bot. 2004 May;55(400):1177-86. Epub 2004 Apr 8.

PMID:
15073223
32.

Protein phosphorylation can regulate metabolite concentrations rather than control flux: the example of glycogen synthase.

Schafer JR, Fell DA, Rothman D, Shulman RG.

Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1485-90. Epub 2004 Jan 26.

33.

Dynamic simulation of pollutant effects on the threonine pathway in Escherichia coli.

Chassagnole C, Quentin E, Fell DA, de Atauri P, Mazat JP.

C R Biol. 2003 May;326(5):501-8.

PMID:
12886877
34.

Metabolic pathways in the post-genome era.

Papin JA, Price ND, Wiback SJ, Fell DA, Palsson BO.

Trends Biochem Sci. 2003 May;28(5):250-8. Review.

PMID:
12765837
35.

Elementary modes analysis of photosynthate metabolism in the chloroplast stroma.

Poolman MG, Fell DA, Raines CA.

Eur J Biochem. 2003 Feb;270(3):430-9.

36.
37.

Metabolic control analysis of anaerobic glycolysis in human hibernating myocardium replaces traditional concepts of flux control.

Vogt AM, Nef H, Schaper J, Poolman M, Fell DA, Kübler W, Elsässer A.

FEBS Lett. 2002 Apr 24;517(1-3):245-50.

38.
39.

Regulation of glycolytic flux in ischemic preconditioning. A study employing metabolic control analysis.

Vogt AM, Poolman M, Ackermann C, Yildiz M, Schoels W, Fell DA, Kubler W.

J Biol Chem. 2002 Jul 5;277(27):24411-9. Epub 2002 May 2.

40.

Beyond genomics.

Fell DA.

Trends Genet. 2001 Dec;17(12):680-2. No abstract available.

PMID:
11718905
41.

The small world inside large metabolic networks.

Wagner A, Fell DA.

Proc Biol Sci. 2001 Sep 7;268(1478):1803-10.

42.

Control of the threonine-synthesis pathway in Escherichia coli: a theoretical and experimental approach.

Chassagnole C, Fell DA, Raïs B, Kudla B, Mazat JP.

Biochem J. 2001 Jun 1;356(Pt 2):433-44.

43.

Threonine synthesis from aspartate in Escherichia coli cell-free extracts: pathway dynamics.

Raïs B, Chassagnole C, Letellier T, Fell DA, Mazat JP.

Biochem J. 2001 Jun 1;356(Pt 2):425-32.

44.

An integrated study of threonine-pathway enzyme kinetics in Escherichia coli.

Chassagnole C, Raïs B, Quentin E, Fell DA, Mazat JP.

Biochem J. 2001 Jun 1;356(Pt 2):415-23.

45.

Computer modelling and experimental evidence for two steady states in the photosynthetic Calvin cycle.

Poolman MG, Olçer H, Lloyd JC, Raines CA, Fell DA.

Eur J Biochem. 2001 May;268(10):2810-6.

46.

The small world of metabolism.

Fell DA, Wagner A.

Nat Biotechnol. 2000 Nov;18(11):1121-2. No abstract available.

PMID:
11062388
48.

Modelling photosynthesis and its control.

Poolman MG, Fell DA, Thomas S.

J Exp Bot. 2000 Feb;51 Spec No:319-28.

PMID:
10938839
49.

Signal transduction and the control of expression of enzyme activity.

Fell DA.

Adv Enzyme Regul. 2000;40:35-46. Review. No abstract available.

PMID:
10828344
50.

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