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Items: 8

1.

Nilotinib as Coadjuvant Treatment with Doxorubicin in Patients with Sarcomas: A Phase I Trial of the Spanish Group for Research on Sarcoma.

Alemany R, Moura DS, Redondo A, Martinez-Trufero J, Calabuig S, Saus C, Obrador-Hevia A, Ramos R, Villar VH, Valverde C, Vaz MA, Medina J, Felipe-Abrio I, Hindi N, Taron M, Martin-Broto J.

Clin Cancer Res. 2018 Nov 1;24(21):5239-5249. doi: 10.1158/1078-0432.CCR-18-0851. Epub 2018 Jul 23.

PMID:
30037815
2.

Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells.

Martinez-Font E, Felipe-Abrio I, Calabuig-Fariñas S, Ramos R, Terrasa J, Vögler O, Alemany R, Martín-Broto J, Obrador-Hevia A.

Mol Cancer Ther. 2017 Jun;16(6):1166-1176. doi: 10.1158/1535-7163.MCT-16-0585. Epub 2017 Mar 14.

3.

Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1).

Perez M, Peinado-Serrano J, Garcia-Heredia JM, Felipe-Abrio I, Tous C, Ferrer I, Martin-Broto J, Saez C, Carnero A.

Oncotarget. 2016 Oct 11;7(41):67033-67046. doi: 10.18632/oncotarget.11475.

4.

RG7112, a small-molecule inhibitor of MDM2, enhances trabectedin response in soft tissue sarcomas.

Obrador-Hevia A, Martinez-Font E, Felipe-Abrio I, Calabuig-Fariñas S, Serra-Sitjar M, López-Guerrero JA, Ramos R, Alemany R, Martín-Broto J.

Cancer Invest. 2015;33(9):440-50. doi: 10.3109/07357907.2015.1064534. Epub 2015 Aug 17.

PMID:
26288114
5.

RG7112, a Small-Molecule Inhibitor of MDM2, Enhances Trabectedin Response in Soft Tissue Sarcomas.

Obrador-Hevia A, Martinez-Font E, Felipe-Abrio I, Calabuig-Fariñas S, Serra-Sitjar M, López-Guerrero JA, Ramos R, Alemany R, Martín-Broto J.

Cancer Invest. 2015 Aug 17. [Epub ahead of print]

PMID:
26279182
6.

RNA polymerase II contributes to preventing transcription-mediated replication fork stalls.

Felipe-Abrio I, Lafuente-Barquero J, García-Rubio ML, Aguilera A.

EMBO J. 2015 Jan 13;34(2):236-50. doi: 10.15252/embj.201488544. Epub 2014 Dec 1.

7.

Coordinated control of replication and transcription by a SAPK protects genomic integrity.

Duch A, Felipe-Abrio I, Barroso S, Yaakov G, García-Rubio M, Aguilera A, de Nadal E, Posas F.

Nature. 2013 Jan 3;493(7430):116-9. doi: 10.1038/nature11675. Epub 2012 Nov 25.

PMID:
23178807
8.

The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants.

Gómez-González B, Felipe-Abrio I, Aguilera A.

Mol Cell Biol. 2009 Oct;29(19):5203-13. doi: 10.1128/MCB.00402-09. Epub 2009 Aug 3.

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