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Items: 1 to 50 of 142

1.

Molecular and immunofluorescence-based quantification of male and female gametocytes in low-density P. falciparum infections and their relevance for transmission.

Gruenberg M, Hofmann NE, Nate E, Karl S, Robinson LJ, Lanke K, Smith TA, Bousema T, Felger I.

J Infect Dis. 2019 Aug 22. pii: jiz420. doi: 10.1093/infdis/jiz420. [Epub ahead of print]

PMID:
31437280
2.

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp.

Jones S, Kay K, Hodel EM, Chy S, Mbituyumuremyi A, Uwimana A, Menard D, Felger I, Hastings I.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00590-19. doi: 10.1128/AAC.00590-19. Print 2019 Sep.

3.

Author Correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.

Slater HC, Ross A, Felger I, Hofmann NE, Robinson L, Cook J, Gonçalves BP, Björkman A, Ouedraogo AL, Morris U, Msellem M, Koepfli C, Mueller I, Tadesse F, Gadisa E, Das S, Domingo G, Kapulu M, Midega J, Owusu-Agyei S, Nabet C, Piarroux R, Doumbo O, Doumbo SN, Koram K, Lucchi N, Udhayakumar V, Mosha J, Tiono A, Chandramohan D, Gosling R, Mwingira F, Sauerwein R, Paul R, Riley EM, White NJ, Nosten F, Imwong M, Bousema T, Drakeley C, Okell LC.

Nat Commun. 2019 Jun 11;10(1):2644. doi: 10.1038/s41467-019-10790-0.

4.

Highly heterogeneous residual malaria risk in western Thailand.

Nguitragool W, Karl S, White M, Koepfli C, Felger I, Singhasivanon P, Mueller I, Sattabongkot J.

Int J Parasitol. 2019 May;49(6):455-462. doi: 10.1016/j.ijpara.2019.01.004. Epub 2019 Apr 4.

PMID:
30954453
5.

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.

Slater HC, Ross A, Felger I, Hofmann NE, Robinson L, Cook J, Gonçalves BP, Björkman A, Ouedraogo AL, Morris U, Msellem M, Koepfli C, Mueller I, Tadesse F, Gadisa E, Das S, Domingo G, Kapulu M, Midega J, Owusu-Agyei S, Nabet C, Piarroux R, Doumbo O, Doumbo SN, Koram K, Lucchi N, Udhayakumar V, Mosha J, Tiono A, Chandramohan D, Gosling R, Mwingira F, Sauerwein R, Paul R, Riley EM, White NJ, Nosten F, Imwong M, Bousema T, Drakeley C, Okell LC.

Nat Commun. 2019 Mar 29;10(1):1433. doi: 10.1038/s41467-019-09441-1. Erratum in: Nat Commun. 2019 Jun 11;10(1):2644.

6.

Longitudinal tracking and quantification of individual Plasmodium falciparum clones in complex infections.

Lerch A, Koepfli C, Hofmann NE, Kattenberg JH, Rosanas-Urgell A, Betuela I, Mueller I, Felger I.

Sci Rep. 2019 Mar 4;9(1):3333. doi: 10.1038/s41598-019-39656-7.

7.

Indigenous Plasmodium malariae Infection in an Endemic Population at the Thai-Myanmar Border.

Yorsaeng R, Saeseu T, Chotivanich K, Felger I, Wampfler R, Cui L, Mueller I, Sattabongkot J, Nguitragool W.

Am J Trop Med Hyg. 2019 May;100(5):1164-1169. doi: 10.4269/ajtmh.18-0597.

PMID:
30793693
8.

A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes.

Meerstein-Kessel L, Andolina C, Carrio E, Mahamar A, Sawa P, Diawara H, van de Vegte-Bolmer M, Stone W, Collins KA, Schneider P, Dicko A, Drakeley C, Felger I, Voss T, Lanke K, Bousema T.

Malar J. 2018 Nov 29;17(1):441. doi: 10.1186/s12936-018-2584-y.

9.

Diagnostic Performance of Conventional and Ultrasensitive Rapid Diagnostic Tests for Malaria in Febrile Outpatients in Tanzania.

Hofmann NE, Antunes Moniz C, Holzschuh A, Keitel K, Boillat-Blanco N, Kagoro F, Samaka J, Mbarack Z, Ding XC, González IJ, Genton B, D'Acremont V, Felger I.

J Infect Dis. 2019 Apr 16;219(9):1490-1498. doi: 10.1093/infdis/jiy676.

10.

Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community cross-sectional study.

Hofmann NE, Gruenberg M, Nate E, Ura A, Rodriguez-Rodriguez D, Salib M, Mueller I, Smith TA, Laman M, Robinson LJ, Felger I.

Lancet Infect Dis. 2018 Oct;18(10):1108-1116. doi: 10.1016/S1473-3099(18)30411-0. Epub 2018 Aug 28.

PMID:
30170986
11.

The Candidate Blood-stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase 1 Trial in Exposed and Nonexposed Volunteers.

Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo RW, Theisen M, Thierry AC, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo SA.

Clin Infect Dis. 2019 Jan 18;68(3):466-474. doi: 10.1093/cid/ciy514.

PMID:
29945169
12.

Plasmodium vivax and Plasmodium falciparum infection dynamics: re-infections, recrudescences and relapses.

White MT, Karl S, Koepfli C, Longley RJ, Hofmann NE, Wampfler R, Felger I, Smith T, Nguitragool W, Sattabongkot J, Robinson L, Ghani A, Mueller I.

Malar J. 2018 Apr 17;17(1):170. doi: 10.1186/s12936-018-2318-1.

13.

High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon.

Almeida ACG, Kuehn A, Castro AJM, Vitor-Silva S, Figueiredo EFG, Brasil LW, Brito MAM, Sampaio VS, Bassat Q, Felger I, Tadei WP, Monteiro WM, Mueller I, Lacerda MVG.

Parasit Vectors. 2018 Mar 20;11(1):194. doi: 10.1186/s13071-018-2787-7.

14.

Human migration and the spread of malaria parasites to the New World.

Rodrigues PT, Valdivia HO, de Oliveira TC, Alves JMP, Duarte AMRC, Cerutti-Junior C, Buery JC, Brito CFA, de Souza JC Jr, Hirano ZMB, Bueno MG, Catão-Dias JL, Malafronte RS, Ladeia-Andrade S, Mita T, Santamaria AM, Calzada JE, Tantular IS, Kawamoto F, Raijmakers LRJ, Mueller I, Pacheco MA, Escalante AA, Felger I, Ferreira MU.

Sci Rep. 2018 Jan 31;8(1):1993. doi: 10.1038/s41598-018-19554-0.

15.

Plasmodium vivax molecular diagnostics in community surveys: pitfalls and solutions.

Gruenberg M, Moniz CA, Hofmann NE, Wampfler R, Koepfli C, Mueller I, Monteiro WM, Lacerda M, de Melo GC, Kuehn A, Siqueira AM, Felger I.

Malar J. 2018 Jan 30;17(1):55. doi: 10.1186/s12936-018-2201-0. Review.

16.

Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections.

Lerch A, Koepfli C, Hofmann NE, Messerli C, Wilcox S, Kattenberg JH, Betuela I, O'Connor L, Mueller I, Felger I.

BMC Genomics. 2017 Nov 13;18(1):864. doi: 10.1186/s12864-017-4260-y.

17.

Very high carriage of gametocytes in asymptomatic low-density Plasmodium falciparum and P. vivax infections in western Thailand.

Nguitragool W, Mueller I, Kumpitak C, Saeseu T, Bantuchai S, Yorsaeng R, Yimsamran S, Maneeboonyang W, Sa-Angchai P, Chaimungkun W, Rukmanee P, Puangsa-Art S, Thanyavanich N, Koepfli C, Felger I, Sattabongkot J, Singhasivanon P.

Parasit Vectors. 2017 Oct 24;10(1):512. doi: 10.1186/s13071-017-2407-y.

18.

The complex relationship of exposure to new Plasmodium infections and incidence of clinical malaria in Papua New Guinea.

Hofmann NE, Karl S, Wampfler R, Kiniboro B, Teliki A, Iga J, Waltmann A, Betuela I, Felger I, Robinson LJ, Mueller I.

Elife. 2017 Sep 1;6. pii: e23708. doi: 10.7554/eLife.23708.

19.

Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum.

Wampfler R, Hofmann NE, Karl S, Betuela I, Kinboro B, Lorry L, Silkey M, Robinson LJ, Mueller I, Felger I.

PLoS Negl Trop Dis. 2017 Jul 21;11(7):e0005753. doi: 10.1371/journal.pntd.0005753. eCollection 2017 Jul.

20.

Cohort profile: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) - A prospective HIV cohort in rural Tanzania.

Letang E, Kalinjuma AV, Glass TR, Gamell A, Mapesi H, Sikalengo GR, Luwanda LB, Mnzava D, Ntamatungiro AJ, Ndaki R, Francis G, Vanobberghen F, Furrer H, Klimkait T, Felger I, Tanner M, Hatz C, Weisser M, Battegay M, Kiularco Study Group.

Swiss Med Wkly. 2017 Jul 4;147:w14485. doi: 10.4414/smw.2017.14485. eCollection 2017.

21.

Natural immune response to Plasmodium vivax alpha-helical coiled coil protein motifs and its association with the risk of P. vivax malaria.

Céspedes N, Li Wai Suen CSN, Koepfli C, França CT, Felger I, Nebie I, Arévalo-Herrera M, Mueller I, Corradin G, Herrera S.

PLoS One. 2017 Jun 26;12(6):e0179863. doi: 10.1371/journal.pone.0179863. eCollection 2017.

22.

Strengthening HIV therapy and care in rural Tanzania affects rates of viral suppression.

Ntamatungiro AJ, Muri L, Glass TR, Erb S, Battegay M, Furrer H, Hatz C, Tanner M, Felger I, Klimkait T, Letang E; KIULARCO Study Group.

J Antimicrob Chemother. 2017 Jul 1;72(7):2069-2074. doi: 10.1093/jac/dkx095.

PMID:
28387865
23.

Asymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmar.

Zaw MT, Thant M, Hlaing TM, Aung NZ, Thu M, Phumchuea K, Phusri K, Saeseu T, Yorsaeng R, Nguitragool W, Felger I, Kaewkungwal J, Cui L, Sattabongkot J.

Malar J. 2017 Apr 4;16(1):138. doi: 10.1186/s12936-017-1789-9.

24.

Defining the next generation of Plasmodium vivax diagnostic tests for control and elimination: Target product profiles.

Ding XC, Ade MP, Baird JK, Cheng Q, Cunningham J, Dhorda M, Drakeley C, Felger I, Gamboa D, Harbers M, Herrera S, Lucchi N, Mayor A, Mueller I, Sattabongkot J, Ratsimbason A, Richards J, Tanner M, González IJ.

PLoS Negl Trop Dis. 2017 Apr 3;11(4):e0005516. doi: 10.1371/journal.pntd.0005516. eCollection 2017 Apr.

25.

The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia.

Tadesse FG, van den Hoogen L, Lanke K, Schildkraut J, Tetteh K, Aseffa A, Mamo H, Sauerwein R, Felger I, Drakeley C, Gadissa E, Bousema T.

Malar J. 2017 Mar 3;16(1):99. doi: 10.1186/s12936-017-1749-4.

26.

Fixed-Dose Artesunate-Amodiaquine Combination vs Chloroquine for Treatment of Uncomplicated Blood Stage P. vivax Infection in the Brazilian Amazon: An Open-Label Randomized, Controlled Trial.

Siqueira AM, Alencar AC, Melo GC, Magalhaes BL, Machado K, Alencar Filho AC, Kuehn A, Marques MM, Manso MC, Felger I, Vieira JL, Lameyre V, Daniel-Ribeiro CT, Lacerda MV.

Clin Infect Dis. 2017 Jan 15;64(2):166-174. doi: 10.1093/cid/ciw706. Epub 2016 Oct 20. Erratum in: Clin Infect Dis. 2017 May 15;64(10):1468.

27.

Comparison of Leishmania typing results obtained from 16 European clinical laboratories in 2014.

Van der Auwera G, Bart A, Chicharro C, Cortes S, Davidsson L, Di Muccio T, Dujardin JC, Felger I, Paglia MG, Grimm F, Harms G, Jaffe CL, Manser M, Ravel C, Robert-Gangneux F, Roelfsema J, Töz S, Verweij JJ, Chiodini PL.

Euro Surveill. 2016 Dec 8;21(49). pii: 30418. doi: 10.2807/1560-7917.ES.2016.21.49.30418.

28.

Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR).

Koepfli C, Nguitragool W, Hofmann NE, Robinson LJ, Ome-Kaius M, Sattabongkot J, Felger I, Mueller I.

Sci Rep. 2016 Dec 16;6:39183. doi: 10.1038/srep39183.

29.

Critical Evaluation of Molecular Monitoring in Malaria Drug Efficacy Trials and Pitfalls of Length-Polymorphic Markers.

Messerli C, Hofmann NE, Beck HP, Felger I.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e01500-16. doi: 10.1128/AAC.01500-16. Print 2017 Jan.

30.

Comparison of molecular quantification of Plasmodium falciparum gametocytes by Pfs25 qRT-PCR and QT-NASBA in relation to mosquito infectivity.

Pett H, Gonçalves BP, Dicko A, Nébié I, Tiono AB, Lanke K, Bradley J, Chen I, Diawara H, Mahamar A, Soumare HM, Traore SF, Baber I, Sirima SB, Sauerwein R, Brown J, Gosling R, Felger I, Drakeley C, Bousema T.

Malar J. 2016 Nov 8;15(1):539.

31.

Spatial Effects on the Multiplicity of Plasmodium falciparum Infections.

Karl S, White MT, Milne GJ, Gurarie D, Hay SI, Barry AE, Felger I, Mueller I.

PLoS One. 2016 Oct 6;11(10):e0164054. doi: 10.1371/journal.pone.0164054. eCollection 2016.

32.

Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania: an emerging public health concern.

Muri L, Gamell A, Ntamatungiro AJ, Glass TR, Luwanda LB, Battegay M, Furrer H, Hatz C, Tanner M, Felger I, Klimkait T, Letang E; KIULARCO Study Group.

AIDS. 2017 Jan 2;31(1):61-70.

33.

The Incidence and Differential Seasonal Patterns of Plasmodium vivax Primary Infections and Relapses in a Cohort of Children in Papua New Guinea.

Ross A, Koepfli C, Schoepflin S, Timinao L, Siba P, Smith T, Mueller I, Felger I, Tanner M.

PLoS Negl Trop Dis. 2016 May 4;10(5):e0004582. doi: 10.1371/journal.pntd.0004582. eCollection 2016 May.

34.

A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa.

Gamell A, Muri L, Ntamatungiro A, Nyogea D, Luwanda LB, Hatz C, Battegay M, Felger I, Tanner M, Klimkait T, Letang E.

Open Forum Infect Dis. 2015 Dec 17;3(1):ofv199. doi: 10.1093/ofid/ofv199. eCollection 2016 Jan.

35.

Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model.

Robinson LJ, Wampfler R, Betuela I, Karl S, White MT, Li Wai Suen CS, Hofmann NE, Kinboro B, Waltmann A, Brewster J, Lorry L, Tarongka N, Samol L, Silkey M, Bassat Q, Siba PM, Schofield L, Felger I, Mueller I.

PLoS Med. 2015 Oct 27;12(10):e1001891. doi: 10.1371/journal.pmed.1001891. eCollection 2015 Oct.

36.

Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network.

Escalante AA, Ferreira MU, Vinetz JM, Volkman SK, Cui L, Gamboa D, Krogstad DJ, Barry AE, Carlton JM, van Eijk AM, Pradhan K, Mueller I, Greenhouse B, Pacheco MA, Vallejo AF, Herrera S, Felger I.

Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):79-86. doi: 10.4269/ajtmh.15-0005. Epub 2015 Aug 10.

37.

Asymptomatic Plasmodium falciparum infections may not be shortened by acquired immunity.

Bretscher MT, Maire N, Felger I, Owusu-Agyei S, Smith T.

Malar J. 2015 Aug 4;14:294. doi: 10.1186/s12936-015-0813-1.

38.

Plasmodium vivax Diversity and Population Structure across Four Continents.

Koepfli C, Rodrigues PT, Antao T, Orjuela-Sánchez P, Van den Eede P, Gamboa D, van Hong N, Bendezu J, Erhart A, Barnadas C, Ratsimbasoa A, Menard D, Severini C, Menegon M, Nour BY, Karunaweera N, Mueller I, Ferreira MU, Felger I.

PLoS Negl Trop Dis. 2015 Jun 30;9(6):e0003872. doi: 10.1371/journal.pntd.0003872. eCollection 2015.

39.

Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea.

Koepfli C, Robinson LJ, Rarau P, Salib M, Sambale N, Wampfler R, Betuela I, Nuitragool W, Barry AE, Siba P, Felger I, Mueller I.

PLoS One. 2015 May 21;10(5):e0126747. doi: 10.1371/journal.pone.0126747. eCollection 2015.

40.

Plasmodium vivax populations are more genetically diverse and less structured than sympatric Plasmodium falciparum populations.

Jennison C, Arnott A, Tessier N, Tavul L, Koepfli C, Felger I, Siba PM, Reeder JC, Bahlo M, Mueller I, Barry AE.

PLoS Negl Trop Dis. 2015 Apr 15;9(4):e0003634. doi: 10.1371/journal.pntd.0003634. eCollection 2015 Apr.

41.

Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets.

Hofmann N, Mwingira F, Shekalaghe S, Robinson LJ, Mueller I, Felger I.

PLoS Med. 2015 Mar 3;12(3):e1001788. doi: 10.1371/journal.pmed.1001788. eCollection 2015 Mar.

42.

Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains.

Balam S, Olugbile S, Servis C, Diakité M, D'Alessandro A, Frank G, Moret R, Nebie I, Tanner M, Felger I, Smith T, Kajava AV, Spertini F, Corradin G.

Malar J. 2014 Dec 19;13:510. doi: 10.1186/1475-2875-13-510.

43.

Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response.

Stanisic DI, Fowkes FJ, Koinari M, Javati S, Lin E, Kiniboro B, Richards JS, Robinson LJ, Schofield L, Kazura JW, King CL, Zimmerman P, Felger I, Siba PM, Mueller I, Beeson JG.

Infect Immun. 2015 Feb;83(2):646-60. doi: 10.1128/IAI.02398-14. Epub 2014 Nov 24.

44.
45.

Asymptomatic malaria infections: detectability, transmissibility and public health relevance.

Bousema T, Okell L, Felger I, Drakeley C.

Nat Rev Microbiol. 2014 Dec;12(12):833-40. doi: 10.1038/nrmicro3364. Epub 2014 Oct 20. Review.

PMID:
25329408
46.

Heterochromatin protein 1 secures survival and transmission of malaria parasites.

Brancucci NMB, Bertschi NL, Zhu L, Niederwieser I, Chin WH, Wampfler R, Freymond C, Rottmann M, Felger I, Bozdech Z, Voss TS.

Cell Host Microbe. 2014 Aug 13;16(2):165-176. doi: 10.1016/j.chom.2014.07.004.

47.

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

Céspedes N, Habel C, Lopez-Perez M, Castellanos A, Kajava AV, Servis C, Felger I, Moret R, Arévalo-Herrera M, Corradin G, Herrera S.

PLoS One. 2014 Jun 24;9(6):e100440. doi: 10.1371/journal.pone.0100440. eCollection 2014.

48.

Novel genotyping tools for investigating transmission dynamics of Plasmodium falciparum.

Wampfler R, Timinao L, Beck HP, Soulama I, Tiono AB, Siba P, Mueller I, Felger I.

J Infect Dis. 2014 Oct 15;210(8):1188-97. doi: 10.1093/infdis/jiu236. Epub 2014 Apr 25.

49.

Antigenicity and immunogenicity of a novel Plasmodium vivax circumsporozoite derived synthetic vaccine construct.

Céspedes N, Jiménez E, Lopez-Perez M, Rubiano K, Felger I, Alonso P, Arévalo-Herrera M, Corradin G, Herrera S.

Vaccine. 2014 May 30;32(26):3179-86. doi: 10.1016/j.vaccine.2014.04.007. Epub 2014 Apr 13.

PMID:
24731811
50.

Development of a simple microarray for genotyping HIV-1 drug resistance mutations in the reverse transcriptase gene in rural Tanzania.

Masimba P, Gare J, Klimkait T, Tanner M, Felger I.

Trop Med Int Health. 2014 Jun;19(6):664-671. doi: 10.1111/tmi.12289. Epub 2014 Mar 21.

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