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Items: 1 to 50 of 849

1.

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge.

Lo MK, Feldmann F, Gary JM, Jordan R, Bannister R, Cronin J, Patel NR, Klena JD, Nichol ST, Cihlar T, Zaki SR, Feldmann H, Spiropoulou CF, de Wit E.

Sci Transl Med. 2019 May 29;11(494). pii: eaau9242. doi: 10.1126/scitranslmed.aau9242.

PMID:
31142680
2.

Antiviral Innate Responses Induced by VSV-EBOV Vaccination Contribute to Rapid Protection.

Menicucci AR, Jankeel A, Feldmann H, Marzi A, Messaoudi I.

MBio. 2019 May 28;10(3). pii: e00597-19. doi: 10.1128/mBio.00597-19.

3.

Differential Innate Immune Responses Elicited by Nipah Virus and Cedar Virus Correlate with Disparate In Vivo Pathogenesis in Hamsters.

Schountz T, Campbell C, Wagner K, Rovnak J, Martellaro C, DeBuysscher BL, Feldmann H, Prescott J.

Viruses. 2019 Mar 22;11(3). pii: E291. doi: 10.3390/v11030291.

4.

Gamma Irradiation as an Effective Method for Inactivation of Emerging Viral Pathogens.

Feldmann F, Shupert WL, Haddock E, Twardoski B, Feldmann H.

Am J Trop Med Hyg. 2019 May;100(5):1275-1277. doi: 10.4269/ajtmh.18-0937.

PMID:
30860018
5.

In the absence of UCP1-mediated diet-induced thermogenesis, obesity is augmented even in the obesity-resistant 129S mouse strain.

Luijten IHN, Feldmann HM, von Essen G, Cannon B, Nedergaard J.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E729-E740. doi: 10.1152/ajpendo.00020.2019. Epub 2019 Feb 26.

6.

Protection Against Marburg Virus Using a Recombinant VSV-Vaccine Depends on T and B Cell Activation.

Marzi A, Menicucci AR, Engelmann F, Callison J, Horne EJ, Feldmann F, Jankeel A, Feldmann H, Messaoudi I.

Front Immunol. 2019 Jan 22;9:3071. doi: 10.3389/fimmu.2018.03071. eCollection 2018.

7.

Prophylactic efficacy of a human monoclonal antibody against MERS-CoV in the common marmoset.

de Wit E, Feldmann F, Horne E, Okumura A, Cameroni E, Haddock E, Saturday G, Scott D, Gopal R, Zambon M, Corti D, Feldmann H.

Antiviral Res. 2019 Mar;163:70-74. doi: 10.1016/j.antiviral.2019.01.016. Epub 2019 Jan 24.

PMID:
30684561
8.

Two recombinant human monoclonal antibodies that protect against lethal Andes hantavirus infection in vivo.

Garrido JL, Prescott J, Calvo M, Bravo F, Alvarez R, Salas A, Riquelme R, Rioseco ML, Williamson BN, Haddock E, Feldmann H, Barria MI.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaat6420. doi: 10.1126/scitranslmed.aat6420. Erratum in: Sci Transl Med. 2019 Jan 16;11(475):.

PMID:
30463919
9.

Recent advances in understanding Crimean-Congo hemorrhagic fever virus.

Hawman DW, Feldmann H.

F1000Res. 2018 Oct 29;7. pii: F1000 Faculty Rev-1715. doi: 10.12688/f1000research.16189.1. eCollection 2018. Review.

10.

Distinct Biological Phenotypes of Marburg and Ravn Virus Infection in Macaques.

Nicholas VV, Rosenke R, Feldmann F, Long D, Thomas T, Scott DP, Feldmann H, Marzi A.

J Infect Dis. 2018 Nov 22;218(suppl_5):S458-S465. doi: 10.1093/infdis/jiy456.

PMID:
30215737
11.

Ebola: Lessons on Vaccine Development.

Feldmann H, Feldmann F, Marzi A.

Annu Rev Microbiol. 2018 Sep 8;72:423-446. doi: 10.1146/annurev-micro-090817-062414.

PMID:
30200851
12.

Tip Your Cap for Ebola Virus Neutralization.

Best SM, Feldmann H.

Immunity. 2018 Aug 21;49(2):204-206. doi: 10.1016/j.immuni.2018.08.001.

PMID:
30134198
13.

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice.

Lavender KJ, Williamson BN, Saturday G, Martellaro C, Griffin A, Hasenkrug KJ, Feldmann H, Prescott J.

J Infect Dis. 2018 Nov 22;218(suppl_5):S409-S417. doi: 10.1093/infdis/jiy269.

PMID:
30085162
14.

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle.

Martin S, Chiramel AI, Schmidt ML, Chen YC, Whitt N, Watt A, Dunham EC, Shifflett K, Traeger S, Leske A, Buehler E, Martellaro C, Brandt J, Wendt L, Müller A, Peitsch S, Best SM, Stech J, Finke S, Römer-Oberdörfer A, Groseth A, Feldmann H, Hoenen T.

Genome Med. 2018 Aug 7;10(1):58. doi: 10.1186/s13073-018-0570-1.

15.

Human Polyclonal Antibodies Produced by Transchromosomal Cattle Provide Partial Protection Against Lethal Zaire Ebolavirus Challenge in Rhesus Macaques.

Rosenke K, Bounds CE, Hanley PW, Saturday G, Sullivan E, Wu H, Jiao JA, Feldmann H, Schmaljohn C, Safronetz D.

J Infect Dis. 2018 Nov 22;218(suppl_5):S658-S661. doi: 10.1093/infdis/jiy430.

PMID:
30053153
16.

A VSV-based Zika virus vaccine protects mice from lethal challenge.

Emanuel J, Callison J, Dowd KA, Pierson TC, Feldmann H, Marzi A.

Sci Rep. 2018 Jul 23;8(1):11043. doi: 10.1038/s41598-018-29401-x.

17.

Lifecycle modelling systems support inosine monophosphate dehydrogenase (IMPDH) as a pro-viral factor and antiviral target for New World arenaviruses.

Dunham EC, Leske A, Shifflett K, Watt A, Feldmann H, Hoenen T, Groseth A.

Antiviral Res. 2018 Sep;157:140-150. doi: 10.1016/j.antiviral.2018.07.009. Epub 2018 Jul 19.

PMID:
30031760
18.

Nucleocapsid protein-based vaccine provides protection in mice against lethal Crimean-Congo hemorrhagic fever virus challenge.

Zivcec M, Safronetz D, Scott DP, Robertson S, Feldmann H.

PLoS Negl Trop Dis. 2018 Jul 16;12(7):e0006628. doi: 10.1371/journal.pntd.0006628. eCollection 2018 Jul.

19.

Single-Nucleotide Polymorphisms in Human NPC1 Influence Filovirus Entry Into Cells.

Kondoh T, Letko M, Munster VJ, Manzoor R, Maruyama J, Furuyama W, Miyamoto H, Shigeno A, Fujikura D, Takadate Y, Yoshida R, Igarashi M, Feldmann H, Marzi A, Takada A.

J Infect Dis. 2018 Nov 22;218(suppl_5):S397-S402. doi: 10.1093/infdis/jiy248.

PMID:
30010949
20.

Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice.

Hawman DW, Haddock E, Meade-White K, Williamson B, Hanley PW, Rosenke K, Komeno T, Furuta Y, Gowen BB, Feldmann H.

Antiviral Res. 2018 Sep;157:18-26. doi: 10.1016/j.antiviral.2018.06.013. Epub 2018 Jun 21.

PMID:
29936152
21.

Monoclonal Antibody Cocktail Protects Hamsters From Lethal Marburg Virus Infection.

Marzi A, Haddock E, Kajihara M, Feldmann H, Takada A.

J Infect Dis. 2018 Nov 22;218(suppl_5):S662-S665. doi: 10.1093/infdis/jiy235.

PMID:
29889266
22.

Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets.

de Wit E, Feldmann F, Okumura A, Horne E, Haddock E, Saturday G, Scott D, Erlandson KJ, Stahl N, Lipsich L, Kyratsous CA, Feldmann H.

Antiviral Res. 2018 Aug;156:64-71. doi: 10.1016/j.antiviral.2018.06.006. Epub 2018 Jun 7.

PMID:
29885377
23.

Use of Favipiravir to Treat Lassa Virus Infection in Macaques.

Rosenke K, Feldmann H, Westover JB, Hanley PW, Martellaro C, Feldmann F, Saturday G, Lovaglio J, Scott DP, Furuta Y, Komeno T, Gowen BB, Safronetz D.

Emerg Infect Dis. 2018 Sep;24(9):1696-1699. doi: 10.3201/eid2409.180233. Epub 2018 Sep 17.

24.

The Effect of Plasmodium on the Outcome of Ebola Virus Infection in a Mouse Model.

Rosenke K, Mercado-Hernandez R, Cronin J, Conteh S, Duffy P, Feldmann H, de Wit E.

J Infect Dis. 2018 Nov 22;218(suppl_5):S434-S437. doi: 10.1093/infdis/jiy236.

PMID:
29878224
25.

Ebola Virus Infection in Commonly Used Laboratory Mouse Strains.

Haddock E, Feldmann H, Marzi A.

J Infect Dis. 2018 Nov 22;218(suppl_5):S453-S457. doi: 10.1093/infdis/jiy208.

PMID:
29878128
26.

The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials.

Suder E, Furuyama W, Feldmann H, Marzi A, de Wit E.

Hum Vaccin Immunother. 2018;14(9):2107-2113. doi: 10.1080/21645515.2018.1473698. Epub 2018 Jun 18. Review.

27.

Recently Identified Mutations in the Ebola Virus-Makona Genome Do Not Alter Pathogenicity in Animal Models.

Marzi A, Chadinah S, Haddock E, Feldmann F, Arndt N, Martellaro C, Scott DP, Hanley PW, Nyenswah TG, Sow S, Massaquoi M, Feldmann H.

Cell Rep. 2018 May 8;23(6):1806-1816. doi: 10.1016/j.celrep.2018.04.027.

28.

Post-exposure treatments for Ebola and Marburg virus infections.

Cross RW, Mire CE, Feldmann H, Geisbert TW.

Nat Rev Drug Discov. 2018 May 4. doi: 10.1038/nrd.2018.73. [Epub ahead of print] No abstract available.

PMID:
29725132
29.

Lethal Zika Virus Disease Models in Young and Older Interferon α/β Receptor Knock Out Mice.

Marzi A, Emanuel J, Callison J, McNally KL, Arndt N, Chadinha S, Martellaro C, Rosenke R, Scott DP, Safronetz D, Whitehead SS, Best SM, Feldmann H.

Front Cell Infect Microbiol. 2018 Apr 11;8:117. doi: 10.3389/fcimb.2018.00117. eCollection 2018.

30.

Virus in Semen and the Risk of Sexual Transmission.

Feldmann H.

N Engl J Med. 2018 Apr 12;378(15):1440-1441. doi: 10.1056/NEJMe1803212. No abstract available.

31.

A cynomolgus macaque model for Crimean-Congo haemorrhagic fever.

Haddock E, Feldmann F, Hawman DW, Zivcec M, Hanley PW, Saturday G, Scott DP, Thomas T, Korva M, Avšič-Županc T, Safronetz D, Feldmann H.

Nat Microbiol. 2018 May;3(5):556-562. doi: 10.1038/s41564-018-0141-7. Epub 2018 Apr 9.

PMID:
29632370
32.

Filoviruses: Ecology, Molecular Biology, and Evolution.

Emanuel J, Marzi A, Feldmann H.

Adv Virus Res. 2018;100:189-221. doi: 10.1016/bs.aivir.2017.12.002. Epub 2018 Feb 1. Review.

PMID:
29551136
33.

Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques.

Prescott J, Falzarano D, de Wit E, Hardcastle K, Feldmann F, Haddock E, Scott D, Feldmann H, Munster VJ.

Front Immunol. 2018 Feb 12;9:205. doi: 10.3389/fimmu.2018.00205. eCollection 2018.

34.

Post-exposure treatments for Ebola and Marburg virus infections.

Cross RW, Mire CE, Feldmann H, Geisbert TW.

Nat Rev Drug Discov. 2018 Jun;17(6):413-434. doi: 10.1038/nrd.2017.251. Epub 2018 Jan 29. Review. Erratum in: Nat Rev Drug Discov. 2018 May 04;:.

PMID:
29375139
35.

Seroprevalence of Rift Valley Fever Virus Antibodies in Cattle in Mali, 2005-2014.

Subudhi S, Dakouo M, Sloan A, Stein DR, Grolla A, Jones S, Dibernardo A, Rosenke K, Sas M, Traore A, Lindsay R, Groschup MH, Misra V, Feldmann H, Sogoba N, Safronetz D, Niang M.

Am J Trop Med Hyg. 2018 Mar;98(3):872-874. doi: 10.4269/ajtmh.17-0841. Epub 2018 Jan 18.

36.

A Single Dose of Modified Vaccinia Ankara expressing Ebola Virus Like Particles Protects Nonhuman Primates from Lethal Ebola Virus Challenge.

Domi A, Feldmann F, Basu R, McCurley N, Shifflett K, Emanuel J, Hellerstein MS, Guirakhoo F, Orlandi C, Flinko R, Lewis GK, Hanley PW, Feldmann H, Robinson HL, Marzi A.

Sci Rep. 2018 Jan 16;8(1):864. doi: 10.1038/s41598-017-19041-y.

37.

1918 H1N1 Influenza Virus Replicates and Induces Proinflammatory Cytokine Responses in Extrarespiratory Tissues of Ferrets.

de Wit E, Siegers JY, Cronin JM, Weatherman S, van den Brand JM, Leijten LM, van Run P, Begeman L, van den Ham HJ, Andeweg AC, Bushmaker T, Scott DP, Saturday G, Munster VJ, Feldmann H, van Riel D.

J Infect Dis. 2018 Mar 28;217(8):1237-1246. doi: 10.1093/infdis/jiy003.

38.

Differential Ability of Pandemic and Seasonal H1N1 Influenza A Viruses To Alter the Function of Human Neutrophils.

Malachowa N, Freedman B, Sturdevant DE, Kobayashi SD, Nair V, Feldmann F, Starr T, Steele-Mortimer O, Kash JC, Taubenberger JK, Feldmann H, DeLeo FR.

mSphere. 2018 Jan 3;3(1). pii: e00567-17. doi: 10.1128/mSphereDirect.00567-17. eCollection 2018 Jan-Feb.

39.

Severity of Disease in Humanized Mice Infected With Ebola Virus or Reston Virus Is Associated With Magnitude of Early Viral Replication in Liver.

Spengler JR, Saturday G, Lavender KJ, Martellaro C, Keck JG, Nichol ST, Spiropoulou CF, Feldmann H, Prescott J.

J Infect Dis. 2017 Dec 27;217(1):58-63. doi: 10.1093/infdis/jix562.

40.

Transmission of henipaviruses.

Weatherman S, Feldmann H, de Wit E.

Curr Opin Virol. 2018 Feb;28:7-11. doi: 10.1016/j.coviro.2017.09.004. Epub 2017 Oct 14. Review.

41.

The Crux of Ebola Diagnostics.

Strong JE, Feldmann H.

J Infect Dis. 2017 Dec 12;216(11):1340-1342. doi: 10.1093/infdis/jix490. No abstract available.

42.

Human immune system mouse models of Ebola virus infection.

Spengler JR, Prescott J, Feldmann H, Spiropoulou CF.

Curr Opin Virol. 2017 Aug;25:90-96. doi: 10.1016/j.coviro.2017.07.028. Epub 2017 Aug 12. Review.

43.

Serosurvey of Crimean-Congo Hemorrhagic Fever Virus in Cattle, Mali, West Africa.

Maiga O, Sas MA, Rosenke K, Kamissoko B, Mertens M, Sogoba N, Traore A, Sangare M, Niang M, Schwan TG, Maiga HM, Traore SF, Feldmann H, Safronetz D, Groschup MH.

Am J Trop Med Hyg. 2017 Jun;96(6):1341-1345. doi: 10.4269/ajtmh.16-0818.

44.

Dromedary camels in northern Mali have high seropositivity to MERS-CoV.

Falzarano D, Kamissoko B, de Wit E, Maïga O, Cronin J, Samaké K, Traoré A, Milne-Price S, Munster VJ, Sogoba N, Niang M, Safronetz D, Feldmann H.

One Health. 2017 Mar 10;3:41-43. doi: 10.1016/j.onehlt.2017.03.003. eCollection 2017 Jun.

45.

Ebolavirus: An Overview of Molecular and Clinical Pathogenesis.

Vine V, Scott DP, Feldmann H.

Methods Mol Biol. 2017;1628:39-50. doi: 10.1007/978-1-4939-7116-9_3.

PMID:
28573609
46.

Reverse Genetics Systems for Filoviruses.

Hoenen T, Feldmann H.

Methods Mol Biol. 2017;1602:159-170. doi: 10.1007/978-1-4939-6964-7_11.

PMID:
28508220
47.

Transcriptomic analysis reveals a previously unknown role for CD8+ T-cells in rVSV-EBOV mediated protection.

Menicucci AR, Sureshchandra S, Marzi A, Feldmann H, Messaoudi I.

Sci Rep. 2017 Apr 20;7(1):919. doi: 10.1038/s41598-017-01032-8.

48.

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

van Doremalen N, Falzarano D, Ying T, de Wit E, Bushmaker T, Feldmann F, Okumura A, Wang Y, Scott DP, Hanley PW, Feldmann H, Dimitrov DS, Munster VJ.

Antiviral Res. 2017 Jul;143:30-37. doi: 10.1016/j.antiviral.2017.03.025. Epub 2017 Apr 5.

PMID:
28389142
49.

Domestic Pig Unlikely Reservoir for MERS-CoV.

de Wit E, Feldmann F, Horne E, Martellaro C, Haddock E, Bushmaker T, Rosenke K, Okumura A, Rosenke R, Saturday G, Scott D, Feldmann H.

Emerg Infect Dis. 2017 Jun;23(6):985-988. doi: 10.3201/eid2306.170096. Epub 2017 Jun 15.

50.

Immunobiology of Ebola and Lassa virus infections.

Prescott JB, Marzi A, Safronetz D, Robertson SJ, Feldmann H, Best SM.

Nat Rev Immunol. 2017 Mar;17(3):195-207. doi: 10.1038/nri.2016.138. Epub 2017 Jan 23. Review.

PMID:
28111475

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