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Items: 1 to 50 of 114

1.

A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters.

van Doremalen N, Lambe T, Sebastian S, Bushmaker T, Fischer R, Feldmann F, Haddock E, Letko M, Avanzato VA, Rissanen I, LaCasse R, Scott D, Bowden TA, Gilbert S, Munster V.

PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007462. doi: 10.1371/journal.pntd.0007462. [Epub ahead of print]

2.

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge.

Lo MK, Feldmann F, Gary JM, Jordan R, Bannister R, Cronin J, Patel NR, Klena JD, Nichol ST, Cihlar T, Zaki SR, Feldmann H, Spiropoulou CF, de Wit E.

Sci Transl Med. 2019 May 29;11(494). pii: eaau9242. doi: 10.1126/scitranslmed.aau9242.

PMID:
31142680
3.

Ebolavirus polymerase uses an unconventional genome replication mechanism.

Deflubé LR, Cressey TN, Hume AJ, Olejnik J, Haddock E, Feldmann F, Ebihara H, Fearns R, Mühlberger E.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8535-8543. doi: 10.1073/pnas.1815745116. Epub 2019 Apr 8.

PMID:
30962389
4.

Gamma Irradiation as an Effective Method for Inactivation of Emerging Viral Pathogens.

Feldmann F, Shupert WL, Haddock E, Twardoski B, Feldmann H.

Am J Trop Med Hyg. 2019 May;100(5):1275-1277. doi: 10.4269/ajtmh.18-0937.

PMID:
30860018
5.

Protection Against Marburg Virus Using a Recombinant VSV-Vaccine Depends on T and B Cell Activation.

Marzi A, Menicucci AR, Engelmann F, Callison J, Horne EJ, Feldmann F, Jankeel A, Feldmann H, Messaoudi I.

Front Immunol. 2019 Jan 22;9:3071. doi: 10.3389/fimmu.2018.03071. eCollection 2018.

6.

Prophylactic efficacy of a human monoclonal antibody against MERS-CoV in the common marmoset.

de Wit E, Feldmann F, Horne E, Okumura A, Cameroni E, Haddock E, Saturday G, Scott D, Gopal R, Zambon M, Corti D, Feldmann H.

Antiviral Res. 2019 Mar;163:70-74. doi: 10.1016/j.antiviral.2019.01.016. Epub 2019 Jan 24.

PMID:
30684561
7.

Distinct Biological Phenotypes of Marburg and Ravn Virus Infection in Macaques.

Nicholas VV, Rosenke R, Feldmann F, Long D, Thomas T, Scott DP, Feldmann H, Marzi A.

J Infect Dis. 2018 Nov 22;218(suppl_5):S458-S465. doi: 10.1093/infdis/jiy456.

PMID:
30215737
8.

Ebola: Lessons on Vaccine Development.

Feldmann H, Feldmann F, Marzi A.

Annu Rev Microbiol. 2018 Sep 8;72:423-446. doi: 10.1146/annurev-micro-090817-062414.

PMID:
30200851
9.

Compatibility of Maximum-Containment Virus-Inactivation Protocols With Identification of Bacterial Coinfections by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.

Matson MJ, Stock F, Shupert WL, Bushmaker T, Feldmann F, Bishop WB, Frank KM, Dekker JP, Chertow DS, Munster VJ.

J Infect Dis. 2018 Nov 22;218(suppl_5):S297-S300. doi: 10.1093/infdis/jiy292.

PMID:
29982557
10.

Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets.

de Wit E, Feldmann F, Okumura A, Horne E, Haddock E, Saturday G, Scott D, Erlandson KJ, Stahl N, Lipsich L, Kyratsous CA, Feldmann H.

Antiviral Res. 2018 Aug;156:64-71. doi: 10.1016/j.antiviral.2018.06.006. Epub 2018 Jun 7.

PMID:
29885377
11.

Use of Favipiravir to Treat Lassa Virus Infection in Macaques.

Rosenke K, Feldmann H, Westover JB, Hanley PW, Martellaro C, Feldmann F, Saturday G, Lovaglio J, Scott DP, Furuta Y, Komeno T, Gowen BB, Safronetz D.

Emerg Infect Dis. 2018 Sep;24(9):1696-1699. doi: 10.3201/eid2409.180233. Epub 2018 Sep 17.

12.

Recently Identified Mutations in the Ebola Virus-Makona Genome Do Not Alter Pathogenicity in Animal Models.

Marzi A, Chadinah S, Haddock E, Feldmann F, Arndt N, Martellaro C, Scott DP, Hanley PW, Nyenswah TG, Sow S, Massaquoi M, Feldmann H.

Cell Rep. 2018 May 8;23(6):1806-1816. doi: 10.1016/j.celrep.2018.04.027.

13.

A cynomolgus macaque model for Crimean-Congo haemorrhagic fever.

Haddock E, Feldmann F, Hawman DW, Zivcec M, Hanley PW, Saturday G, Scott DP, Thomas T, Korva M, Avšič-Županc T, Safronetz D, Feldmann H.

Nat Microbiol. 2018 May;3(5):556-562. doi: 10.1038/s41564-018-0141-7. Epub 2018 Apr 9.

PMID:
29632370
14.

Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques.

Prescott J, Falzarano D, de Wit E, Hardcastle K, Feldmann F, Haddock E, Scott D, Feldmann H, Munster VJ.

Front Immunol. 2018 Feb 12;9:205. doi: 10.3389/fimmu.2018.00205. eCollection 2018.

15.

A Single Dose of Modified Vaccinia Ankara expressing Ebola Virus Like Particles Protects Nonhuman Primates from Lethal Ebola Virus Challenge.

Domi A, Feldmann F, Basu R, McCurley N, Shifflett K, Emanuel J, Hellerstein MS, Guirakhoo F, Orlandi C, Flinko R, Lewis GK, Hanley PW, Feldmann H, Robinson HL, Marzi A.

Sci Rep. 2018 Jan 16;8(1):864. doi: 10.1038/s41598-017-19041-y.

16.

Differential Ability of Pandemic and Seasonal H1N1 Influenza A Viruses To Alter the Function of Human Neutrophils.

Malachowa N, Freedman B, Sturdevant DE, Kobayashi SD, Nair V, Feldmann F, Starr T, Steele-Mortimer O, Kash JC, Taubenberger JK, Feldmann H, DeLeo FR.

mSphere. 2018 Jan 3;3(1). pii: e00567-17. doi: 10.1128/mSphereDirect.00567-17. eCollection 2018 Jan-Feb.

17.

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells.

Feldmann F, Schenk B, Martens S, Vandenabeele P, Fulda S.

Oncotarget. 2017 Aug 4;8(40):68208-68220. doi: 10.18632/oncotarget.19919. eCollection 2017 Sep 15.

18.

Pathogenic analysis of the pandemic 2009 H1N1 influenza A viruses in ferrets.

Tsuda Y, Weisend C, Martellaro C, Feldmann F, Haddock E.

J Vet Med Sci. 2017 Aug 18;79(8):1453-1460. doi: 10.1292/jvms.16-0619. Epub 2017 Jul 3.

19.

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

Martens S, Jeong M, Tonnus W, Feldmann F, Hofmans S, Goossens V, Takahashi N, Bräsen JH, Lee EW, Van der Veken P, Joossens J, Augustyns K, Fulda S, Linkermann A, Song J, Vandenabeele P.

Cell Death Dis. 2017 Jun 29;8(6):e2904. doi: 10.1038/cddis.2017.298.

20.

Validating the Inactivation Effectiveness of Chemicals on Ebola Virus.

Haddock E, Feldmann F.

Methods Mol Biol. 2017;1628:251-257. doi: 10.1007/978-1-4939-7116-9_20.

PMID:
28573626
21.

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

van Doremalen N, Falzarano D, Ying T, de Wit E, Bushmaker T, Feldmann F, Okumura A, Wang Y, Scott DP, Hanley PW, Feldmann H, Dimitrov DS, Munster VJ.

Antiviral Res. 2017 Jul;143:30-37. doi: 10.1016/j.antiviral.2017.03.025. Epub 2017 Apr 5.

PMID:
28389142
22.

Domestic Pig Unlikely Reservoir for MERS-CoV.

de Wit E, Feldmann F, Horne E, Martellaro C, Haddock E, Bushmaker T, Rosenke K, Okumura A, Rosenke R, Saturday G, Scott D, Feldmann H.

Emerg Infect Dis. 2017 Jun;23(6):985-988. doi: 10.3201/eid2306.170096. Epub 2017 Jun 15.

23.

Animal Models of Emerging Tick-Borne Phleboviruses: Determining Target Cells in a Lethal Model of SFTSV Infection.

Matsuno K, Orba Y, Maede-White K, Scott D, Feldmann F, Liang M, Ebihara H.

Front Microbiol. 2017 Jan 30;8:104. doi: 10.3389/fmicb.2017.00104. eCollection 2017.

24.

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection.

Dutta M, Robertson SJ, Okumura A, Scott DP, Chang J, Weiss JM, Sturdevant GL, Feldmann F, Haddock E, Chiramel AI, Ponia SS, Dougherty JD, Katze MG, Rasmussen AL, Best SM.

Cell Rep. 2017 Jan 17;18(3):816-829. doi: 10.1016/j.celrep.2016.12.069.

25.

Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents.

Wilson MR, Fedewa G, Stenglein MD, Olejnik J, Rennick LJ, Nambulli S, Feldmann F, Duprex WP, Connor JH, Mühlberger E, DeRisi JL.

mSystems. 2016 Jul 19;1(4). pii: e00058-16. eCollection 2016 Jul-Aug.

26.

Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients.

Rosenke K, Adjemian J, Munster VJ, Marzi A, Falzarano D, Onyango CO, Ochieng M, Juma B, Fischer RJ, Prescott JB, Safronetz D, Omballa V, Owuor C, Hoenen T, Groseth A, Martellaro C, van Doremalen N, Zemtsova G, Self J, Bushmaker T, McNally K, Rowe T, Emery SL, Feldmann F, Williamson BN, Best SM, Nyenswah TG, Grolla A, Strong JE, Kobinger G, Bolay FK, Zoon KC, Stassijns J, Giuliani R, de Smet M, Nichol ST, Fields B, Sprecher A, Massaquoi M, Feldmann H, de Wit E.

Clin Infect Dis. 2016 Oct 15;63(8):1026-33. doi: 10.1093/cid/ciw452. Epub 2016 Aug 15.

27.

Clinical Chemistry of Patients With Ebola in Monrovia, Liberia.

de Wit E, Kramer S, Prescott J, Rosenke K, Falzarano D, Marzi A, Fischer RJ, Safronetz D, Hoenen T, Groseth A, van Doremalen N, Bushmaker T, McNally KL, Feldmann F, Williamson BN, Best SM, Ebihara H, Damiani IA, Adamson B, Zoon KC, Nyenswah TG, Bolay FK, Massaquoi M, Sprecher A, Feldmann H, Munster VJ.

J Infect Dis. 2016 Oct 15;214(suppl 3):S303-S307. Epub 2016 Jul 28.

28.

Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015.

de Wit E, Rosenke K, Fischer RJ, Marzi A, Prescott J, Bushmaker T, van Doremalen N, Emery SL, Falzarano D, Feldmann F, Groseth A, Hoenen T, Juma B, McNally KL, Ochieng M, Omballa V, Onyango CO, Owuor C, Rowe T, Safronetz D, Self J, Williamson BN, Zemtsova G, Grolla A, Kobinger G, Rayfield M, Ströher U, Strong JE, Best SM, Ebihara H, Zoon KC, Nichol ST, Nyenswah TG, Bolay FK, Massaquoi M, Feldmann H, Fields B.

J Infect Dis. 2016 Oct 15;214(suppl 3):S169-S176. Epub 2016 Jun 21.

29.

Effective Chemical Inactivation of Ebola Virus.

Haddock E, Feldmann F, Feldmann H.

Emerg Infect Dis. 2016 Jul;22(7):1292-4. doi: 10.3201/eid2207.160233. Epub 2016 Jul 15.

30.

Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection.

Marzi A, Murphy AA, Feldmann F, Parkins CJ, Haddock E, Hanley PW, Emery MJ, Engelmann F, Messaoudi I, Feldmann H, Jarvis MA.

Sci Rep. 2016 Feb 15;6:21674. doi: 10.1038/srep21674.

31.

The Merits of Malaria Diagnostics during an Ebola Virus Disease Outbreak.

de Wit E, Falzarano D, Onyango C, Rosenke K, Marzi A, Ochieng M, Juma B, Fischer RJ, Prescott JB, Safronetz D, Omballa V, Owuor C, Hoenen T, Groseth A, van Doremalen N, Zemtsova G, Self J, Bushmaker T, McNally K, Rowe T, Emery SL, Feldmann F, Williamson B, Nyenswah TG, Grolla A, Strong JE, Kobinger G, Stroeher U, Rayfield M, Bolay FK, Zoon KC, Stassijns J, Tampellini L, de Smet M, Nichol ST, Fields B, Sprecher A, Feldmann H, Massaquoi M, Munster VJ.

Emerg Infect Dis. 2016 Feb;22(2):323-6. doi: 10.3201/eid2202.151656.

32.

Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool.

Hoenen T, Groseth A, Rosenke K, Fischer RJ, Hoenen A, Judson SD, Martellaro C, Falzarano D, Marzi A, Squires RB, Wollenberg KR, de Wit E, Prescott J, Safronetz D, van Doremalen N, Bushmaker T, Feldmann F, McNally K, Bolay FK, Fields B, Sealy T, Rayfield M, Nichol ST, Zoon KC, Massaquoi M, Munster VJ, Feldmann H.

Emerg Infect Dis. 2016 Feb;22(2):331-4. doi: 10.3201/eid2202.151796.

33.

Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain.

Marzi A, Feldmann F, Hanley PW, Scott DP, Günther S, Feldmann H.

Emerg Infect Dis. 2015 Oct;21(10):1777-83. doi: 10.3201/eid2110.150259.

34.

A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.

Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, Scott DP, Feldmann F, LaCasse R, Meade-White K, Okumura A, Ugen KE, Sardesai NY, Kim JJ, Kobinger G, Feldmann H, Weiner DB.

Sci Transl Med. 2015 Aug 19;7(301):301ra132. doi: 10.1126/scitranslmed.aac7462.

35.

EBOLA VACCINE. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain.

Marzi A, Robertson SJ, Haddock E, Feldmann F, Hanley PW, Scott DP, Strong JE, Kobinger G, Best SM, Feldmann H.

Science. 2015 Aug 14;349(6249):739-42. doi: 10.1126/science.aab3920. Epub 2015 Aug 6.

36.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.

Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG.

J Virol. 2015 Oct;89(20):10399-406. doi: 10.1128/JVI.01736-15. Epub 2015 Aug 5.

37.

Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice.

Gabriel G, Feldmann F, Reimer R, Thiele S, Fischer M, Hartmann E, Bader M, Ebihara H, Hoenen T, Feldmann H.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S316-21. doi: 10.1093/infdis/jiv240. Epub 2015 Jul 16.

38.

Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus.

Matassov D, Marzi A, Latham T, Xu R, Ota-Setlik A, Feldmann F, Geisbert JB, Mire CE, Hamm S, Nowak B, Egan MA, Geisbert TW, Eldridge JH, Feldmann H, Clarke DK.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S443-51. doi: 10.1093/infdis/jiv316. Epub 2015 Jun 24.

39.

Lack of protection against ebola virus from chloroquine in mice and hamsters.

Falzarano D, Safronetz D, Prescott J, Marzi A, Feldmann F, Feldmann H.

Emerg Infect Dis. 2015 Jun;21(6):1065-7. doi: 10.3201/eid2106.150176.

40.

Immune Response to Marburg Virus Angola Infection in Nonhuman Primates.

Fernando L, Qiu X, Melito PL, Williams KJ, Feldmann F, Feldmann H, Jones SM, Alimonti JB.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S234-41. doi: 10.1093/infdis/jiv095. Epub 2015 May 9.

PMID:
25957966
41.

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs.

Hoenen T, Marzi A, Scott DP, Feldmann F, Callison J, Safronetz D, Ebihara H, Feldmann H.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S242-6. doi: 10.1093/infdis/jiv111. Epub 2015 May 9.

42.

A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses.

Safronetz D, Mire C, Rosenke K, Feldmann F, Haddock E, Geisbert T, Feldmann H.

PLoS Negl Trop Dis. 2015 Apr 17;9(4):e0003736. doi: 10.1371/journal.pntd.0003736. eCollection 2015 Apr.

43.

Single-dose live-attenuated vesicular stomatitis virus-based vaccine protects African green monkeys from Nipah virus disease.

Prescott J, DeBuysscher BL, Feldmann F, Gardner DJ, Haddock E, Martellaro C, Scott D, Feldmann H.

Vaccine. 2015 Jun 4;33(24):2823-9. doi: 10.1016/j.vaccine.2015.03.089. Epub 2015 Apr 10.

44.

A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose.

Tsuda Y, Parkins CJ, Caposio P, Feldmann F, Botto S, Ball S, Messaoudi I, Cicin-Sain L, Feldmann H, Jarvis MA.

Vaccine. 2015 May 5;33(19):2261-2266. doi: 10.1016/j.vaccine.2015.03.029. Epub 2015 Mar 25.

45.

Virology. Mutation rate and genotype variation of Ebola virus from Mali case sequences.

Hoenen T, Safronetz D, Groseth A, Wollenberg KR, Koita OA, Diarra B, Fall IS, Haidara FC, Diallo F, Sanogo M, Sarro YS, Kone A, Togo AC, Traore A, Kodio M, Dosseh A, Rosenke K, de Wit E, Feldmann F, Ebihara H, Munster VJ, Zoon KC, Feldmann H, Sow S.

Science. 2015 Apr 3;348(6230):117-9. doi: 10.1126/science.aaa5646. Epub 2015 Mar 26. Erratum in: Science. 2015 May 22;348(6237):aac5674.

46.

Vaccines. An Ebola whole-virus vaccine is protective in nonhuman primates.

Marzi A, Halfmann P, Hill-Batorski L, Feldmann F, Shupert WL, Neumann G, Feldmann H, Kawaoka Y.

Science. 2015 Apr 24;348(6233):439-42. doi: 10.1126/science.aaa4919. Epub 2015 Mar 26.

47.

Vesicular stomatitis virus-based vaccines against Lassa and Ebola viruses.

Marzi A, Feldmann F, Geisbert TW, Feldmann H, Safronetz D.

Emerg Infect Dis. 2015 Feb;21(2):305-7. doi: 10.3201/eid2102.141649.

48.

Complete genome sequences of three ebola virus isolates from the 2014 outbreak in west Africa.

Hoenen T, Groseth A, Feldmann F, Marzi A, Ebihara H, Kobinger G, Günther S, Feldmann H.

Genome Announc. 2014 Dec 18;2(6). pii: e01331-14. doi: 10.1128/genomeA.01331-14.

49.

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG.

Science. 2014 Nov 21;346(6212):987-91. doi: 10.1126/science.1259595. Epub 2014 Oct 30.

50.

Infection with MERS-CoV causes lethal pneumonia in the common marmoset.

Falzarano D, de Wit E, Feldmann F, Rasmussen AL, Okumura A, Peng X, Thomas MJ, van Doremalen N, Haddock E, Nagy L, LaCasse R, Liu T, Zhu J, McLellan JS, Scott DP, Katze MG, Feldmann H, Munster VJ.

PLoS Pathog. 2014 Aug 21;10(8):e1004250. doi: 10.1371/journal.ppat.1004250. eCollection 2014 Aug. Erratum in: PLoS Pathog. 2014 Sep;10(9):e1004431.

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