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Items: 1 to 50 of 83

1.

A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae.

Feldman MF, Mayer Bridwell AE, Scott NE, Vinogradov E, McKee SR, Chavez SM, Twentyman J, Stallings CL, Rosen DA, Harding CM.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18655-18663. doi: 10.1073/pnas.1907833116. Epub 2019 Aug 27.

2.

The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction.

Urusova DV, Kinsella RL, Salinas ND, Haurat MF, Feldman MF, Tolia NH.

J Biol Chem. 2019 Sep 6;294(36):13344-13354. doi: 10.1074/jbc.RA119.009805. Epub 2019 Jul 18.

PMID:
31320476
3.

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes.

Di Venanzio G, Flores-Mireles AL, Calix JJ, Haurat MF, Scott NE, Palmer LD, Potter RF, Hibbing ME, Friedman L, Wang B, Dantas G, Skaar EP, Hultgren SJ, Feldman MF.

Nat Commun. 2019 Jun 24;10(1):2763. doi: 10.1038/s41467-019-10706-y.

4.

Seasonal Changes in the Prevalence of Antibiotic-Susceptible Acinetobacter calcoaceticus-baumannii Complex Isolates Result in Increased Multidrug Resistance Rates During Winter Months.

Burnham JP, Feldman MF, Calix JJ.

Open Forum Infect Dis. 2019 May 22;6(6):ofz245. doi: 10.1093/ofid/ofz245. eCollection 2019 Jun.

5.

Glycoengineering bioconjugate vaccines, therapeutics, and diagnostics in E. coli.

Harding CM, Feldman MF.

Glycobiology. 2019 Jul 1;29(7):519-529. doi: 10.1093/glycob/cwz031.

PMID:
30989179
6.

A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host.

Harding CM, Nasr MA, Scott NE, Goyette-Desjardins G, Nothaft H, Mayer AE, Chavez SM, Huynh JP, Kinsella RL, Szymanski CM, Stallings CL, Segura M, Feldman MF.

Nat Commun. 2019 Feb 21;10(1):891. doi: 10.1038/s41467-019-08869-9.

7.

Multidrug-resistant plasmids repress chromosomally encoded T6SS to enable their dissemination.

Di Venanzio G, Moon KH, Weber BS, Lopez J, Ly PM, Potter RF, Dantas G, Feldman MF.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1378-1383. doi: 10.1073/pnas.1812557116. Epub 2019 Jan 9.

8.

Surface Exposure and Packing of Lipoproteins into Outer Membrane Vesicles Are Coupled Processes in Bacteroides.

Valguarnera E, Scott NE, Azimzadeh P, Feldman MF.

mSphere. 2018 Nov 7;3(6). pii: e00559-18. doi: 10.1128/mSphere.00559-18.

9.

Distinct amino acid residues confer one of three UDP-sugar substrate specificities in Acinetobacter baumannii PglC phosphoglycosyltransferases.

Harding CM, Haurat MF, Vinogradov E, Feldman MF.

Glycobiology. 2018 Jul 1;28(7):522-533. doi: 10.1093/glycob/cwy037.

PMID:
29668902
10.

Expanding the molecular weaponry of bacterial species.

Lopez J, Feldman MF.

J Biol Chem. 2018 Feb 2;293(5):1515-1516. doi: 10.1074/jbc.H118.001463. Epub 2018 Feb 2.

11.

Uncovering the mechanisms of Acinetobacter baumannii virulence.

Harding CM, Hennon SW, Feldman MF.

Nat Rev Microbiol. 2018 Feb;16(2):91-102. doi: 10.1038/nrmicro.2017.148. Epub 2017 Dec 18. Review.

12.

Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in Acinetobacter species.

Kinsella RL, Lopez J, Palmer LD, Salinas ND, Skaar EP, Tolia NH, Feldman MF.

J Biol Chem. 2017 Dec 1;292(48):19628-19638. doi: 10.1074/jbc.M117.808394. Epub 2017 Oct 5.

13.

Glycoengineered Outer Membrane Vesicles as a Platform for Vaccine Development.

Valguarnera E, Feldman MF.

Methods Enzymol. 2017;597:285-310. doi: 10.1016/bs.mie.2017.06.032. Epub 2017 Aug 18.

PMID:
28935107
14.

A Transcriptional Regulatory Mechanism Finely Tunes the Firing of Type VI Secretion System in Response to Bacterial Enemies.

Lazzaro M, Feldman MF, García Véscovi E.

MBio. 2017 Aug 22;8(4). pii: e00559-17. doi: 10.1128/mBio.00559-17.

15.

Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression.

Moon KH, Weber BS, Feldman MF.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00778-17. doi: 10.1128/AAC.00778-17. Print 2017 Sep.

16.

Screening for Secretion of the Type VI Secretion System Protein Hcp by Enzyme-Linked Immunosorbent Assay and Colony Blot.

Weber BS, Ly PM, Feldman MF.

Methods Mol Biol. 2017;1615:465-472. doi: 10.1007/978-1-4939-7033-9_32.

PMID:
28667630
17.

Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems.

Harding CM, Pulido MR, Di Venanzio G, Kinsella RL, Webb AI, Scott NE, Pachón J, Feldman MF.

J Biol Chem. 2017 Jun 2;292(22):9075-9087. doi: 10.1074/jbc.M117.781575. Epub 2017 Apr 3.

18.

LptO (PG0027) Is Required for Lipid A 1-Phosphatase Activity in Porphyromonas gingivalis W50.

Rangarajan M, Aduse-Opoku J, Hashim A, McPhail G, Luklinska Z, Haurat MF, Feldman MF, Curtis MA.

J Bacteriol. 2017 May 9;199(11). pii: e00751-16. doi: 10.1128/JB.00751-16. Print 2017 Jun 1.

19.

The Secrets of Acinetobacter Secretion.

Weber BS, Kinsella RL, Harding CM, Feldman MF.

Trends Microbiol. 2017 Jul;25(7):532-545. doi: 10.1016/j.tim.2017.01.005. Epub 2017 Feb 16. Review.

20.

Correction: The O-Antigen Flippase Wzk Can Substitute for MurJ in Peptidoglycan Synthesis in Helicobacter pylori and Escherichia coli.

Elhenawy W, Davis RM, Fero J, Salama NR, Feldman MF, Ruiz N.

PLoS One. 2017 Jan 23;12(1):e0170518. doi: 10.1371/journal.pone.0170518. eCollection 2017.

21.

Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter.

Piepenbrink KH, Lillehoj E, Harding CM, Labonte JW, Zuo X, Rapp CA, Munson RS Jr, Goldblum SE, Feldman MF, Gray JJ, Sundberg EJ.

J Biol Chem. 2016 Oct 28;291(44):22924-22935. Epub 2016 Sep 15.

22.

Genetic Dissection of the Type VI Secretion System in Acinetobacter and Identification of a Novel Peptidoglycan Hydrolase, TagX, Required for Its Biogenesis.

Weber BS, Hennon SW, Wright MS, Scott NE, de Berardinis V, Foster LJ, Ayala JA, Adams MD, Feldman MF.

MBio. 2016 Oct 11;7(5). pii: e01253-16. doi: 10.1128/mBio.01253-16.

23.

LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella.

Elhenawy W, Bording-Jorgensen M, Valguarnera E, Haurat MF, Wine E, Feldman MF.

MBio. 2016 Jul 12;7(4). pii: e00940-16. doi: 10.1128/mBio.00940-16.

24.

Sugar and Spice Make Bacteria Not Nice: Protein Glycosylation and Its Influence in Pathogenesis.

Valguarnera E, Kinsella RL, Feldman MF.

J Mol Biol. 2016 Aug 14;428(16):3206-3220. doi: 10.1016/j.jmb.2016.04.013. Epub 2016 Apr 20. Review.

PMID:
27107636
25.

Glycoengineered Outer Membrane Vesicles: A Novel Platform for Bacterial Vaccines.

Price NL, Goyette-Desjardins G, Nothaft H, Valguarnera E, Szymanski CM, Segura M, Feldman MF.

Sci Rep. 2016 Apr 22;6:24931. doi: 10.1038/srep24931.

26.

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.

Roier S, Zingl FG, Cakar F, Durakovic S, Kohl P, Eichmann TO, Klug L, Gadermaier B, Weinzerl K, Prassl R, Lass A, Daum G, Reidl J, Feldman MF, Schild S.

Nat Commun. 2016 Jan 25;7:10515. doi: 10.1038/ncomms10515.

27.

Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full Virulence.

Harding CM, Kinsella RL, Palmer LD, Skaar EP, Feldman MF.

PLoS Pathog. 2016 Jan 14;12(1):e1005391. doi: 10.1371/journal.ppat.1005391. eCollection 2016 Jan.

28.

Pathogenic Acinetobacter: from the Cell Surface to Infinity and Beyond.

Weber BS, Harding CM, Feldman MF.

J Bacteriol. 2015 Dec 28;198(6):880-7. doi: 10.1128/JB.00906-15. Review.

29.

Protein O-linked glycosylation in the plant pathogen Ralstonia solanacearum.

Elhenawy W, Scott NE, Tondo ML, Orellano EG, Foster LJ, Feldman MF.

Glycobiology. 2016 Mar;26(3):301-11. doi: 10.1093/glycob/cwv098. Epub 2015 Nov 3.

30.

Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance.

Schieck E, Lartigue C, Frey J, Vozza N, Hegermann J, Miller RA, Valguarnera E, Muriuki C, Meens J, Nene V, Naessens J, Weber J, Lowary TL, Vashee S, Feldman MF, Jores J.

Mol Microbiol. 2016 Jan;99(1):55-70. doi: 10.1111/mmi.13213. Epub 2015 Oct 14.

31.

A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii.

Weber BS, Ly PM, Irwin JN, Pukatzki S, Feldman MF.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9442-7. doi: 10.1073/pnas.1502966112. Epub 2015 Jul 13.

32.

Glyco-engineering O-Antigen-Based Vaccines and Diagnostics in E. coli.

Vozza NF, Feldman MF.

Methods Mol Biol. 2015;1321:57-70. doi: 10.1007/978-1-4939-2760-9_5.

PMID:
26082215
33.

Acinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O-glycosylation of multiple proteins.

Harding CM, Nasr MA, Kinsella RL, Scott NE, Foster LJ, Weber BS, Fiester SE, Actis LA, Tracy EN, Munson RS Jr, Feldman MF.

Mol Microbiol. 2015 Jun;96(5):1023-41. doi: 10.1111/mmi.12986. Epub 2015 Apr 6.

34.

A basis for vaccine development: Comparative characterization of Haemophilus influenzae outer membrane vesicles.

Roier S, Blume T, Klug L, Wagner GE, Elhenawy W, Zangger K, Prassl R, Reidl J, Daum G, Feldman MF, Schild S.

Int J Med Microbiol. 2015 May;305(3):298-309. doi: 10.1016/j.ijmm.2014.12.005. Epub 2014 Dec 18.

PMID:
25592265
35.

Clinical implications of glycoproteomics for Acinetobacter baumannii.

Kinsella RL, Scott NE, Feldman MF.

Expert Rev Proteomics. 2015 Feb;12(1):1-3. doi: 10.1586/14789450.2015.987756. Epub 2014 Dec 11.

PMID:
25496064
36.

Serogroup-specific bacterial engineered glycoproteins as novel antigenic targets for diagnosis of shiga toxin-producing-escherichia coli-associated hemolytic-uremic syndrome.

Melli LJ, Ciocchini AE, Caillava AJ, Vozza N, Chinen I, Rivas M, Feldman MF, Ugalde JE, Comerci DJ.

J Clin Microbiol. 2015 Feb;53(2):528-38. doi: 10.1128/JCM.02262-14. Epub 2014 Dec 3.

37.

Factitious angioedema: a mimic of refractory "angioedema".

Feldman MF, Khan DA, Brown ES, Bernstein JA.

J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):795-7. doi: 10.1016/j.jaip.2014.08.010. Epub 2014 Oct 3. No abstract available.

PMID:
25439375
38.

Clinical, serologic, and histologic features of gluten sensitivity in children.

Feldman MF, Bird JA.

Pediatrics. 2014 Nov;134 Suppl 3:S157-8. doi: 10.1542/peds.2014-1817QQ. No abstract available.

39.

Prokaryotic membrane vesicles: new insights on biogenesis and biological roles.

Haurat MF, Elhenawy W, Feldman MF.

Biol Chem. 2015 Feb;396(2):95-109. doi: 10.1515/hsz-2014-0183. Review.

40.

Production of a recombinant vaccine candidate against Burkholderia pseudomallei exploiting the bacterial N-glycosylation machinery.

Garcia-Quintanilla F, Iwashkiw JA, Price NL, Stratilo C, Feldman MF.

Front Microbiol. 2014 Jul 29;5:381. doi: 10.3389/fmicb.2014.00381. eCollection 2014.

41.

A bacterial engineered glycoprotein as a novel antigen for diagnosis of bovine brucellosis.

Ciocchini AE, Serantes DA, Melli LJ, Guidolin LS, Iwashkiw JA, Elena S, Franco C, Nicola AM, Feldman MF, Comerci DJ, Ugalde JE.

Vet Microbiol. 2014 Aug 27;172(3-4):455-65. doi: 10.1016/j.vetmic.2014.04.014. Epub 2014 Apr 30.

PMID:
24984948
42.

Diversity within the O-linked protein glycosylation systems of acinetobacter species.

Scott NE, Kinsella RL, Edwards AV, Larsen MR, Dutta S, Saba J, Foster LJ, Feldman MF.

Mol Cell Proteomics. 2014 Sep;13(9):2354-70. doi: 10.1074/mcp.M114.038315. Epub 2014 Jun 10.

43.

A general protein O-glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence.

Lithgow KV, Scott NE, Iwashkiw JA, Thomson EL, Foster LJ, Feldman MF, Dennis JJ.

Mol Microbiol. 2014 Apr;92(1):116-37. doi: 10.1111/mmi.12540. Epub 2014 Mar 5.

44.

Oral immunotherapy for food allergy, ready for prime time? Heated egg and milk.

Feldman MF, Bird JA.

Curr Allergy Asthma Rep. 2014 May;14(5):436. doi: 10.1007/s11882-014-0436-6. Review.

PMID:
24671644
45.

Preferential packing of acidic glycosidases and proteases into Bacteroides outer membrane vesicles.

Elhenawy W, Debelyy MO, Feldman MF.

MBio. 2014 Mar 11;5(2):e00909-14. doi: 10.1128/mBio.00909-14.

46.

Evaluating the role of conserved amino acids in bacterial O-oligosaccharyltransferases by in vivo, in vitro and limited proteolysis assays.

Musumeci MA, Faridmoayer A, Watanabe Y, Feldman MF.

Glycobiology. 2014 Jan;24(1):39-50. doi: 10.1093/glycob/cwt087. Epub 2013 Oct 2.

PMID:
24092836
47.

Concurrent automated sequencing of the glycan and peptide portions of O-linked glycopeptide anions by ultraviolet photodissociation mass spectrometry.

Madsen JA, Ko BJ, Xu H, Iwashkiw JA, Robotham SA, Shaw JB, Feldman MF, Brodbelt JS.

Anal Chem. 2013 Oct 1;85(19):9253-61. doi: 10.1021/ac4021177. Epub 2013 Sep 20.

48.

A common pathway for O-linked protein-glycosylation and synthesis of capsule in Acinetobacter baumannii.

Lees-Miller RG, Iwashkiw JA, Scott NE, Seper A, Vinogradov E, Schild S, Feldman MF.

Mol Microbiol. 2013 Sep;89(5):816-30. doi: 10.1111/mmi.12300. Epub 2013 Jul 12.

49.

In vitro glycosylation assay for bacterial oligosaccharyltransferases.

Musumeci MA, Ielmini MV, Feldman MF.

Methods Mol Biol. 2013;1022:161-71. doi: 10.1007/978-1-62703-465-4_13.

PMID:
23765661
50.

Pour some sugar on it: the expanding world of bacterial protein O-linked glycosylation.

Iwashkiw JA, Vozza NF, Kinsella RL, Feldman MF.

Mol Microbiol. 2013 Jul;89(1):14-28. doi: 10.1111/mmi.12265. Epub 2013 Jun 12. Review.

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