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Items: 1 to 50 of 402

1.

Temporal evolution of the microbiome, immune system, and epigenome with disease progression in ALS mice.

Figueroa-Romero C, Guo K, Murdock BJ, Paez-Colasante X, Bassis CM, Mikhail KA, Raue KD, Evans MC, Taubman GF, McDermott AJ, O'Brien PD, Savelieff MG, Hur J, Feldman EL.

Dis Model Mech. 2019 Oct 9. pii: dmm.041947. doi: 10.1242/dmm.041947. [Epub ahead of print]

2.

Response to Caro and Winter.

Harte SE, Clauw DJ, Feldman EL, Watson CJ.

Pain Rep. 2019 Apr 15;4(3):e734. doi: 10.1097/PR9.0000000000000734. eCollection 2019 May-Jun. No abstract available.

3.

Increased lipogenesis and impaired β-oxidation predict type 2 diabetic kidney disease progression in American Indians.

Afshinnia F, Nair V, Lin J, Rajendiran TM, Soni T, Byun J, Sharma K, Fort PE, Gardner TW, Looker HC, Nelson RG, Brosius FC, Feldman EL, Michailidis G, Kretzler M, Pennathur S.

JCI Insight. 2019 Nov 1;4(21). pii: 130317. doi: 10.1172/jci.insight.130317.

4.

The effects of insulin and insulin-like growth factor I on amyloid precursor protein phosphorylation in in vitro and in vivo models of Alzheimer's disease.

Kim B, Elzinga SE, Henn RE, McGinley LM, Feldman EL.

Neurobiol Dis. 2019 Dec;132:104541. doi: 10.1016/j.nbd.2019.104541. Epub 2019 Jul 23. Review.

PMID:
31349033
5.

New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism.

Eid S, Sas KM, Abcouwer SF, Feldman EL, Gardner TW, Pennathur S, Fort PE.

Diabetologia. 2019 Sep;62(9):1539-1549. doi: 10.1007/s00125-019-4959-1. Epub 2019 Jul 25. Review.

PMID:
31346658
6.

ALS/SURV: a modification of the CAFS statistic.

Goutman SA, Brown MB, Cudkowicz M, Atassi N, Feldman EL.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Nov;20(7-8):576-583. doi: 10.1080/21678421.2019.1643375. Epub 2019 Jul 23.

PMID:
31334681
7.

Comparison of Myelin-Associated Glycoprotein With Vincristine for Facial Nerve Inhibition After Bilateral Axotomy in a Transgenic Thy1-Gfp Rat Model.

Ali SA, Hanks JE, Stebbins AW, Cohen ST, Hunter DA, Snyder-Warwick AK, Mackinnon SE, Kupfer RA, Hogikyan ND, Feldman EL, Brenner MJ.

JAMA Facial Plast Surg. 2019 Jun 20. doi: 10.1001/jamafacial.2019.0398. [Epub ahead of print]

PMID:
31219545
8.

Disorders of mitochondrial dynamics in peripheral neuropathy: Clues from hereditary neuropathy and diabetes.

Rumora AE, Savelieff MG, Sakowski SA, Feldman EL.

Int Rev Neurobiol. 2019;145:127-176. doi: 10.1016/bs.irn.2019.05.002. Epub 2019 Jun 6.

PMID:
31208522
9.

Diabetic neuropathy.

Feldman EL, Callaghan BC, Pop-Busui R, Zochodne DW, Wright DE, Bennett DL, Bril V, Russell JW, Viswanathan V.

Nat Rev Dis Primers. 2019 Jun 13;5(1):41. doi: 10.1038/s41572-019-0092-1. Review.

PMID:
31197153
10.

Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials.

Goutman SA, Savelieff MG, Sakowski SA, Feldman EL.

Expert Opin Investig Drugs. 2019 Jun;28(6):525-543. doi: 10.1080/13543784.2019.1627324. Epub 2019 Jun 12. Review. Erratum in: Expert Opin Ther Pat. 2019 Jul 4;:1-7.

PMID:
31189354
11.

Effect of Motor versus Sensory Nerve Autografts on Regeneration and Functional Outcomes of Rat Facial Nerve Reconstruction.

Ali SA, Rosko AJ, Hanks JE, Stebbins AW, Alkhalili O, Hogikyan ND, Feldman EL, Brenner MJ.

Sci Rep. 2019 Jun 7;9(1):8353. doi: 10.1038/s41598-019-44342-9.

12.

Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease?

Elzinga S, Murdock BJ, Guo K, Hayes JM, Tabbey MA, Hur J, Feldman EL.

Exp Neurol. 2019 Oct;320:112967. doi: 10.1016/j.expneurol.2019.112967. Epub 2019 May 28.

PMID:
31145897
13.

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus.

Guo K, Elzinga S, Eid S, Figueroa-Romero C, Hinder LM, Pacut C, Feldman EL, Hur J.

Epigenetics. 2019 Aug;14(8):766-779. doi: 10.1080/15592294.2019.1615352. Epub 2019 May 28.

14.

The Divergent Roles of Dietary Saturated and Monounsaturated Fatty Acids on Nerve Function in Murine Models of Obesity.

Rumora AE, LoGrasso G, Hayes JM, Mendelson FE, Tabbey MA, Haidar JA, Lentz SI, Feldman EL.

J Neurosci. 2019 May 8;39(19):3770-3781. doi: 10.1523/JNEUROSCI.3173-18.2019. Epub 2019 Mar 18.

15.

Correction to: Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone.

de Anda-Jáuregui G, Guo K, McGregor BA, Feldman EL, Hur J.

BMC Syst Biol. 2019 Mar 13;13(1):31. doi: 10.1186/s12918-019-0707-x.

16.

High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis.

Goutman SA, Boss J, Patterson A, Mukherjee B, Batterman S, Feldman EL.

J Neurol Neurosurg Psychiatry. 2019 Aug;90(8):907-912. doi: 10.1136/jnnp-2018-319785. Epub 2019 Feb 13.

PMID:
30760645
17.

Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes.

Hinder LM, Sas KM, O'Brien PD, Backus C, Kayampilly P, Hayes JM, Lin CM, Zhang H, Shanmugam S, Rumora AE, Abcouwer SF, Brosius FC 3rd, Pennathur S, Feldman EL.

Sci Rep. 2019 Jan 29;9(1):881. doi: 10.1038/s41598-018-37376-y.

18.

Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone.

de Anda-Jáuregui G, Guo K, McGregor BA, Feldman EL, Hur J.

BMC Syst Biol. 2019 Jan 7;13(1):1. doi: 10.1186/s12918-018-0674-7. Erratum in: BMC Syst Biol. 2019 Mar 13;13(1):31.

19.

Targeted intraspinal injections to assess therapies in rodent models of neurological disorders.

Chen KS, McGinley LM, Kashlan ON, Hayes JM, Bruno ES, Chang JS, Mendelson FE, Tabbey MA, Johe K, Sakowski SA, Feldman EL.

Nat Protoc. 2019 Feb;14(2):331-349. doi: 10.1038/s41596-018-0095-5.

PMID:
30610242
20.

Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy.

McGregor BA, Eid S, Rumora AE, Murdock B, Guo K, de Anda-Jáuregui G, Porter JE, Feldman EL, Hur J.

Sci Rep. 2018 Dec 5;8(1):17678. doi: 10.1038/s41598-018-36098-5.

21.

Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy.

O'Brien PD, Hinder LM, Rumora AE, Hayes JM, Dauch JR, Backus C, Mendelson FE, Feldman EL.

Dis Model Mech. 2018 Dec 18;11(12). pii: dmm037374. doi: 10.1242/dmm.037374.

22.

Chain length of saturated fatty acids regulates mitochondrial trafficking and function in sensory neurons.

Rumora AE, LoGrasso G, Haidar JA, Dolkowski JJ, Lentz SI, Feldman EL.

J Lipid Res. 2019 Jan;60(1):58-70. doi: 10.1194/jlr.M086843. Epub 2018 Nov 15.

PMID:
30442656
23.

Human neural stem cell transplantation improves cognition in a murine model of Alzheimer's disease.

McGinley LM, Kashlan ON, Bruno ES, Chen KS, Hayes JM, Kashlan SR, Raykin J, Johe K, Murphy GG, Feldman EL.

Sci Rep. 2018 Oct 3;8(1):14776. doi: 10.1038/s41598-018-33017-6.

24.

Abnormal RNA stability in amyotrophic lateral sclerosis.

Tank EM, Figueroa-Romero C, Hinder LM, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen MT, Guo K, Hur J, Ljungman M, Feldman EL, Barmada SJ.

Nat Commun. 2018 Jul 20;9(1):2845. doi: 10.1038/s41467-018-05049-z.

25.

Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.

Malik AM, Miguez RA, Li X, Ho YS, Feldman EL, Barmada SJ.

Elife. 2018 Jul 17;7. pii: e35977. doi: 10.7554/eLife.35977.

26.

Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS.

Goutman SA, Brown MB, Glass JD, Boulis NM, Johe K, Hazel T, Cudkowicz M, Atassi N, Borges L, Patil PG, Sakowski SA, Feldman EL.

Ann Clin Transl Neurol. 2018 May 2;5(6):730-740. doi: 10.1002/acn3.567. eCollection 2018 Jun.

27.

Reply to "Diagnosing Neuropathy in an Obese Patient": Measuring neuropathy in obese populations: Nerve conduction studies.

Callaghan BC, Feldman EL.

Clin Neurophysiol. 2018 Sep;129(9):2050. doi: 10.1016/j.clinph.2018.06.004. Epub 2018 Jun 14. No abstract available.

PMID:
29921550
28.

Measuring neuropathy in obese populations: Challenge accepted. Reply to "Diagnostic accuracy of neuropathy tests in obese population remains elusive".

Callaghan BC, Feldman EL.

Clin Neurophysiol. 2018 Jul;129(7):1504-1505. doi: 10.1016/j.clinph.2018.03.040. Epub 2018 Apr 16. No abstract available.

PMID:
29729887
29.

Diabetes and obesity are the main metabolic drivers of peripheral neuropathy.

Callaghan BC, Gao L, Li Y, Zhou X, Reynolds E, Banerjee M, Pop-Busui R, Feldman EL, Ji L.

Ann Clin Transl Neurol. 2018 Feb 14;5(4):397-405. doi: 10.1002/acn3.531. eCollection 2018 Apr.

30.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A; ITALSGEN Consortium, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L; Genomic Translation for ALS Care (GTAC) Consortium, Moreno CAM, Kamalakaran S, Goldstein DB; ALS Sequencing Consortium, Gitler AD, Harris T, Myers RM; NYGC ALS Consortium, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC; Answer ALS Foundation, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E; Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J; SLAGEN Consortium, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C; French ALS Consortium, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A; Project MinE ALS Sequencing Consortium, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH Jr, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE.

Neuron. 2018 Mar 21;97(6):1268-1283.e6. doi: 10.1016/j.neuron.2018.02.027.

31.

Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story.

Hinder LM, Murdock BJ, Park M, Bender DE, O'Brien PD, Rumora AE, Hur J, Feldman EL.

Exp Neurol. 2018 Jul;305:33-43. doi: 10.1016/j.expneurol.2018.03.011. Epub 2018 Mar 14.

32.

Risk Factors for Incident Diabetic Polyneuropathy in a Cohort With Screen-Detected Type 2 Diabetes Followed for 13 Years: ADDITION-Denmark.

Andersen ST, Witte DR, Dalsgaard EM, Andersen H, Nawroth P, Fleming T, Jensen TM, Finnerup NB, Jensen TS, Lauritzen T, Feldman EL, Callaghan BC, Charles M.

Diabetes Care. 2018 May;41(5):1068-1075. doi: 10.2337/dc17-2062. Epub 2018 Feb 27.

PMID:
29487078
33.

Emerging understanding of the genotype-phenotype relationship in amyotrophic lateral sclerosis.

Goutman SA, Chen KS, Paez-Colasante X, Feldman EL.

Handb Clin Neurol. 2018;148:603-623. doi: 10.1016/B978-0-444-64076-5.00039-9. Review.

PMID:
29478603
34.
35.

Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists.

Callaghan BC, Xia R, Reynolds E, Banerjee M, Burant C, Rothberg A, Pop-Busui R, Villegas-Umana E, Feldman EL.

Clin Neurophysiol. 2018 Mar;129(3):654-662. doi: 10.1016/j.clinph.2018.01.003. Epub 2018 Jan 16.

36.

Reduced intraepidermal nerve fiber density after a sustained increase in insular glutamate: a proof-of-concept study examining the pathogenesis of small fiber pathology in fibromyalgia.

Harte SE, Clauw DJ, Hayes JM, Feldman EL, St Charles IC, Watson CJ.

Pain Rep. 2017 Apr 15;2(3):e590. doi: 10.1097/PR9.0000000000000590. eCollection 2017 May.

37.

Cardiovascular autonomic neuropathy in adolescents and young adults with type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth Cohort Study.

Jaiswal M, Divers J, Urbina EM, Dabelea D, Bell RA, Pettitt DJ, Imperatore G, Pihoker C, Dolan LM, Liese AD, Marcovina S, Linder B, Feldman EL, Pop-Busui R; SEARCH for Diabetes in Youth Study Group.

Pediatr Diabetes. 2018 Jun;19(4):680-689. doi: 10.1111/pedi.12633. Epub 2018 Jan 2.

38.

Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model.

Sas KM, Lin J, Rajendiran TM, Soni T, Nair V, Hinder LM, Jagadish HV, Gardner TW, Abcouwer SF, Brosius FC 3rd, Feldman EL, Kretzler M, Michailidis G, Pennathur S.

J Lipid Res. 2018 Feb;59(2):173-183. doi: 10.1194/jlr.M077222. Epub 2017 Dec 13.

39.

Emergency Department Stroke Care.

Meurer WJ, Ward K, Feldman EL.

JAMA Neurol. 2018 Feb 1;75(2):257-258. doi: 10.1001/jamaneurol.2017.3817. No abstract available.

PMID:
29228082
40.

Immunohistologic analysis of spontaneous recurrent laryngeal nerve reinnervation in a rat model.

Rosko AJ, Kupfer RA, Oh SS, Haring CT, Feldman EL, Hogikyan ND.

Laryngoscope. 2018 Mar;128(3):E117-E122. doi: 10.1002/lary.27004. Epub 2017 Dec 11.

41.

Human neural stem cell transplantation into the corpus callosum of Alzheimer's mice.

McGinley LM, Kashlan ON, Chen KS, Bruno ES, Hayes JM, Backus C, Feldman S, Kashlan BN, Johe K, Feldman EL.

Ann Clin Transl Neurol. 2017 Aug 18;4(10):749-755. doi: 10.1002/acn3.443. eCollection 2017 Oct.

42.

Three-dimensional Imaging and Analysis of Mitochondria within Human Intraepidermal Nerve Fibers.

Hamid HS, Hayes JM, Feldman EL, Lentz SI.

J Vis Exp. 2017 Sep 29;(127). doi: 10.3791/53369.

43.

Correlation of Peripheral Immunity With Rapid Amyotrophic Lateral Sclerosis Progression.

Murdock BJ, Zhou T, Kashlan SR, Little RJ, Goutman SA, Feldman EL.

JAMA Neurol. 2017 Dec 1;74(12):1446-1454. doi: 10.1001/jamaneurol.2017.2255.

44.

Obesity and the nervous system: more questions - Authors' reply.

Callaghan BC, O'Brien PD, Hinder LM, Feldman EL.

Lancet Neurol. 2017 Oct;16(10):774. doi: 10.1016/S1474-4422(17)30293-4. Epub 2017 Sep 12. No abstract available.

PMID:
28920882
45.

Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons.

Rumora AE, Lentz SI, Hinder LM, Jackson SW, Valesano A, Levinson GE, Feldman EL.

FASEB J. 2018 Jan;32(1):195-207. doi: 10.1096/fj.201700206R. Epub 2017 Sep 13.

46.

Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study.

Jaiswal M, Divers J, Dabelea D, Isom S, Bell RA, Martin CL, Pettitt DJ, Saydah S, Pihoker C, Standiford DA, Dolan LM, Marcovina S, Linder B, Liese AD, Pop-Busui R, Feldman EL.

Diabetes Care. 2017 Sep;40(9):1226-1232. doi: 10.2337/dc17-0179. Epub 2017 Jul 3.

47.

Electrodiagnostic tests are unlikely to change management in those with a known cause of typical distal symmetric polyneuropathy.

Callaghan BC, Burke JF, Kerber KA, Albers JW, Feldman EL.

Muscle Nerve. 2017 Sep;56(3):E25. doi: 10.1002/mus.25713. Epub 2017 Jun 22. No abstract available.

48.

Neurological consequences of obesity.

O'Brien PD, Hinder LM, Callaghan BC, Feldman EL.

Lancet Neurol. 2017 Jun;16(6):465-477. doi: 10.1016/S1474-4422(17)30084-4. Review.

49.

Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome.

Hinder LM, O'Brien PD, Hayes JM, Backus C, Solway AP, Sims-Robinson C, Feldman EL.

Dis Model Mech. 2017 Jun 1;10(6):717-725. doi: 10.1242/dmm.028530. Epub 2017 Apr 5.

50.

New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain.

Feldman EL, Nave KA, Jensen TS, Bennett DLH.

Neuron. 2017 Mar 22;93(6):1296-1313. doi: 10.1016/j.neuron.2017.02.005. Review.

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