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Items: 1 to 50 of 52

1.

DLEMMA-MS-Imaging for Identification of Spatially Localized Metabolites and Metabolic Network Map Reconstruction.

Feldberg L, Dong Y, Heinig U, Rogachev I, Aharoni A.

Anal Chem. 2018 Sep 4;90(17):10231-10238. doi: 10.1021/acs.analchem.8b01644. Epub 2018 Aug 16.

PMID:
30063330
2.

Development of a multiplex Endopep-MS assay for simultaneous detection of botulinum toxins A, B and E.

Rosen O, Feldberg L, Yamin TS, Dor E, Barnea A, Weissberg A, Zichel R.

Sci Rep. 2017 Nov 1;7(1):14859. doi: 10.1038/s41598-017-14911-x.

3.

Optimization of SNAP-25-derived peptide substrate for improved detection of botulinum A in the Endopep-MS assay.

Rosen O, Feldberg L, Dor E, Gura S, Zichel R.

Anal Biochem. 2017 Jul 1;528:34-37. doi: 10.1016/j.ab.2017.04.012. Epub 2017 Apr 24.

PMID:
28450105
4.

Early, Real-Time Medical Diagnosis of Botulism by Endopeptidase-Mass Spectrometry.

Rosen O, Feldberg L, Gura S, Brosh-Nissimov T, Guri A, Zimhony O, Shapiro E, Beth-Din A, Stein D, Ozeri E, Barnea A, Turgeman A, Ben David A, Schwartz A, Elhanany E, Diamant E, Yitzhaki S, Zichel R.

Clin Infect Dis. 2015 Dec 15;61(12):e58-61. doi: 10.1093/cid/civ861. Epub 2015 Sep 28.

PMID:
26420800
5.

A new peptide substrate for enhanced botulinum neurotoxin type B detection by endopeptidase-liquid chromatography-tandem mass spectrometry/multiple reaction monitoring assay.

Rosen O, Feldberg L, Gura S, Zichel R.

Anal Biochem. 2015 Mar 15;473:7-10. doi: 10.1016/j.ab.2014.09.016. Epub 2014 Sep 30.

PMID:
25277815
6.

Improved detection of botulinum type E by rational design of a new peptide substrate for endopeptidase-mass spectrometry assay.

Rosen O, Feldberg L, Gura S, Zichel R.

Anal Biochem. 2014 Jul 1;456:50-2. doi: 10.1016/j.ab.2014.03.024. Epub 2014 Apr 8.

PMID:
24721293
7.

Primary repair of zone I flexor tendon injuries.

Bidwai AS, Feldberg L.

Hand Surg. 2013;18(1):79-83. doi: 10.1142/S0218810413500159.

PMID:
23413856
8.

The button-over-nail technique for Zone I flexor tendon injuries.

Bidwai AS, Feldberg L.

Hand Surg. 2012;17(3):365-9. doi: 10.1142/S0218810412500323.

PMID:
23061947
9.

The homodigital subcutaneous flap for soft tissue coverage of the dorsum of the finger: a case series.

Hold P, Tehrani H, Feldberg L.

Hand (N Y). 2010 Dec;5(4):458-60. doi: 10.1007/s11552-010-9279-3. Epub 2010 Jun 16. No abstract available.

10.

Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors.

Dehnhardt CM, Venkatesan AM, Chen Z, Delos-Santos E, Ayral-Kaloustian S, Brooijmans N, Yu K, Hollander I, Feldberg L, Lucas J, Mallon R.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4773-8. doi: 10.1016/j.bmcl.2011.06.063. Epub 2011 Jun 21.

PMID:
21763134
11.

Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor.

Mallon R, Feldberg LR, Lucas J, Chaudhary I, Dehnhardt C, Santos ED, Chen Z, dos Santos O, Ayral-Kaloustian S, Venkatesan A, Hollander I.

Clin Cancer Res. 2011 May 15;17(10):3193-203. doi: 10.1158/1078-0432.CCR-10-1694. Epub 2011 Feb 15.

12.

Synthesis of phosphatidylinositol 3-kinase (PI3K) inhibitory analogues of the sponge meroterpenoid liphagal.

Pereira AR, Strangman WK, Marion F, Feldberg L, Roll D, Mallon R, Hollander I, Andersen RJ.

J Med Chem. 2010 Dec 23;53(24):8523-33. doi: 10.1021/jm100531u. Epub 2010 Dec 1.

PMID:
21121631
13.

PKI-179: an orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor.

Venkatesan AM, Chen Z, dos Santos O, Dehnhardt C, Santos ED, Ayral-Kaloustian S, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Chaudhary I, Mansour TS.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5869-73. doi: 10.1016/j.bmcl.2010.07.104. Epub 2010 Jul 30.

PMID:
20797855
14.

Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor.

Mallon R, Hollander I, Feldberg L, Lucas J, Soloveva V, Venkatesan A, Dehnhardt C, Delos Santos E, Chen Z, Dos Santos O, Ayral-Kaloustian S, Gibbons J.

Mol Cancer Ther. 2010 Apr;9(4):976-84. doi: 10.1158/1535-7163.MCT-09-0954. Epub 2010 Apr 6.

15.

Synthesis and SAR of novel 4-morpholinopyrrolopyrimidine derivatives as potent phosphatidylinositol 3-kinase inhibitors.

Chen Z, Venkatesan AM, Dehnhardt CM, Ayral-Kaloustian S, Brooijmans N, Mallon R, Feldberg L, Hollander I, Lucas J, Yu K, Kong F, Mansour TS.

J Med Chem. 2010 Apr 22;53(8):3169-82. doi: 10.1021/jm901783v.

PMID:
20334367
16.

B-Raf kinase inhibitors: hit enrichment through scaffold hopping.

Gopalsamy A, Shi M, Hu Y, Lee F, Feldberg L, Frommer E, Kim S, Collins K, Wojciechowicz D, Mallon R.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2431-4. doi: 10.1016/j.bmcl.2010.03.030. Epub 2010 Mar 9.

PMID:
20307980
17.

Novel benzofuran-3-one indole inhibitors of PI3 kinase-alpha and the mammalian target of rapamycin: hit to lead studies.

Bursavich MG, Brooijmans N, Feldberg L, Hollander I, Kim S, Lombardi S, Park K, Mallon R, Gilbert AM.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2586-90. doi: 10.1016/j.bmcl.2010.02.082. Epub 2010 Feb 23.

PMID:
20303263
18.

Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor.

Venkatesan AM, Dehnhardt CM, Delos Santos E, Chen Z, Dos Santos O, Ayral-Kaloustian S, Khafizova G, Brooijmans N, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Gibbons J, Abraham RT, Chaudhary I, Mansour TS.

J Med Chem. 2010 Mar 25;53(6):2636-45. doi: 10.1021/jm901830p.

PMID:
20166697
19.

Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-alpha: Hit to lead studies.

Gilbert AM, Nowak P, Brooijmans N, Bursavich MG, Dehnhardt C, Santos ED, Feldberg LR, Hollander I, Kim S, Lombardi S, Park K, Venkatesan AM, Mallon R.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):636-9. doi: 10.1016/j.bmcl.2009.11.051. Epub 2009 Dec 5.

PMID:
19969455
20.

Lead optimization of N-3-substituted 7-morpholinotriazolopyrimidines as dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors: discovery of PKI-402.

Dehnhardt CM, Venkatesan AM, Delos Santos E, Chen Z, Santos O, Ayral-Kaloustian S, Brooijmans N, Mallon R, Hollander I, Feldberg L, Lucas J, Chaudhary I, Yu K, Gibbons J, Abraham R, Mansour TS.

J Med Chem. 2010 Jan 28;53(2):798-810. doi: 10.1021/jm9014982.

PMID:
19968288
21.

Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors.

Venkatesan AM, Dehnhardt CM, Chen Z, Santos ED, Dos Santos O, Bursavich M, Gilbert AM, Ellingboe JW, Ayral-Kaloustian S, Khafizova G, Brooijmans N, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Gibbons J, Abraham R, Mansour TS.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):653-6. doi: 10.1016/j.bmcl.2009.11.057. Epub 2009 Dec 1.

PMID:
19954970
22.

Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.

Gopalsamy A, Ciszewski G, Shi M, Berger D, Hu Y, Lee F, Feldberg L, Frommer E, Kim S, Collins K, Wojciechowicz D, Mallon R.

Bioorg Med Chem Lett. 2009 Dec 15;19(24):6890-2. doi: 10.1016/j.bmcl.2009.10.074. Epub 2009 Oct 22.

PMID:
19884006
23.

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.

Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. doi: 10.1016/j.bmcl.2009.10.049. Epub 2009 Oct 26.

PMID:
19864136
25.

Degradation of sulfur mustard on KF/Al2O3 supports: insights into the products and the reactions mechanisms.

Zafrani Y, Goldvaser M, Dagan S, Feldberg L, Mizrahi D, Waysbort D, Gershonov E, Columbus I.

J Org Chem. 2009 Nov 6;74(21):8464-7. doi: 10.1021/jo901713c.

PMID:
19817399
26.

Replantation and subsequent reconstruction strategies of a guillotine amputated foot in an 11--year old child: a four-year follow up.

Wickham MH, Brackley PT, McPhail J, Feldberg L, Carsi B, McArthur P.

J Plast Reconstr Aesthet Surg. 2010 May;63(5):e503-5. doi: 10.1016/j.bjps.2009.09.003. Epub 2009 Oct 3. No abstract available.

PMID:
19801207
27.

Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens.

Williams DE, Hollander I, Feldberg L, Frommer E, Mallon R, Tahir A, van Soest R, Andersen RJ.

J Nat Prod. 2009 Jun;72(6):1106-9. doi: 10.1021/np900042r.

PMID:
19485329
28.

Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors.

Gopalsamy A, Ciszewski G, Hu Y, Lee F, Feldberg L, Frommer E, Kim S, Collins K, Wojciechowicz D, Mallon R.

Bioorg Med Chem Lett. 2009 May 15;19(10):2735-8. doi: 10.1016/j.bmcl.2009.03.129. Epub 2009 Mar 28.

PMID:
19362830
29.

4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors.

Berger DM, Dutia M, Powell D, Floyd MB, Torres N, Mallon R, Wojciechowicz D, Kim S, Feldberg L, Collins K, Chaudhary I.

Bioorg Med Chem. 2008 Oct 15;16(20):9202-11. doi: 10.1016/j.bmc.2008.09.009. Epub 2008 Sep 9.

PMID:
18815050
30.

Re: ulnar artery pseudoaneurysm post-carpal tunnel decompression.

Saour S, Khan IU, Feldberg L.

J Hand Surg Eur Vol. 2008 Jun;33(3):391-2. doi: 10.1177/1753193408090116. No abstract available.

PMID:
18562384
31.

Gene expression and metabolism in tomato fruit surface tissues.

Mintz-Oron S, Mandel T, Rogachev I, Feldberg L, Lotan O, Yativ M, Wang Z, Jetter R, Venger I, Adato A, Aharoni A.

Plant Physiol. 2008 Jun;147(2):823-51. doi: 10.1104/pp.108.116004. Epub 2008 Apr 25.

32.

A directly labeled TR-FRET assay for monitoring phosphoinositide-3-kinase activity.

Yang X, Li P, Feldberg L, Kim SC, Bowman M, Hollander I, Mallon R, Wolf SF.

Comb Chem High Throughput Screen. 2006 Aug;9(7):565-70.

PMID:
16925516
33.

Liphagal, a Selective inhibitor of PI3 kinase alpha isolated from the sponge akacoralliphaga: structure elucidation and biomimetic synthesis.

Marion F, Williams DE, Patrick BO, Hollander I, Mallon R, Kim SC, Roll DM, Feldberg L, Van Soest R, Andersen RJ.

Org Lett. 2006 Jan 19;8(2):321-4.

PMID:
16408905
34.

Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.

Mallon R, Feldberg L, Kim S, Collins K, Wojciechowicz D, Kohler C, Kovacs D, Discafani C, Zhang N, Wu B, Floyd B, Powell D, Berger D.

Mol Cancer Ther. 2004 Jun;3(6):755-62.

35.
36.

Pseudoainhum in chronic psoriasis.

Almond SL, Curley RK, Feldberg L.

Br J Dermatol. 2003 Nov;149(5):1064-6.

PMID:
14632817
37.

Synthesis and evaluation of 4-anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade.

Berger D, Dutia M, Powell D, Wu B, Wissner A, Boschelli DH, Floyd MB, Zhang N, Torres N, Levin J, Du X, Wojciechowicz D, Discafani C, Kohler C, Kim SC, Feldberg LR, Collins K, Mallon R.

Bioorg Med Chem Lett. 2003 Sep 15;13(18):3031-4.

PMID:
12941327
38.

Mycobacterium malmoense septic arthritis.

Whitehead SE, Allen KD, Abernethy VE, Feldberg L, Ridyard JB.

J Infect. 2003 Jan;46(1):60-1.

PMID:
12504611
39.

The Martin-Whiston hand table.

Liew SH, Martin AJ, Feldberg LE, Vinod Kumar PA.

Plast Reconstr Surg. 2003 Jan;111(1):509-10. No abstract available.

PMID:
12496646
40.

Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).

Tasdemir D, Mallon R, Greenstein M, Feldberg LR, Kim SC, Collins K, Wojciechowicz D, Mangalindan GC, ConcepciĆ³n GP, Harper MK, Ireland CM.

J Med Chem. 2002 Jan 17;45(2):529-32.

PMID:
11784156
41.

An enzyme-linked immunosorbent assay for the Raf/MEK1/MAPK signaling cascade.

Mallon R, Feldberg LR, Kim SC, Collins K, Wojciechowicz D, Hollander I, Kovacs ED, Kohler C.

Anal Biochem. 2001 Jul 1;294(1):48-54.

PMID:
11412005
42.

Bizarre parosteal osteochondromatous proliferation with cortical invasion.

Helliwell TR, O'Connor MA, Ritchie DA, Feldberg L, Stilwell JH, Jane MJ.

Skeletal Radiol. 2001 May;30(5):282-5.

PMID:
11407720
43.

MEK (MAPKK) inhibitors. Part 2: structure-activity relationships of 4-anilino-3-cyano-6,7-dialkoxyquinolines.

Zhang N, Wu B, Eudy N, Wang Y, Ye F, Powell D, Wissner A, Feldberg LR, Kim SC, Mallon R, Kovacs ED, Toral-Barza L, Kohler CA.

Bioorg Med Chem Lett. 2001 Jun 4;11(11):1407-10.

PMID:
11378365
44.

Primary repair of dog bites to the face: 40 cases.

Javaid M, Feldberg L, Gipson M.

J R Soc Med. 1998 Aug;91(8):414-6.

45.

Textured or smooth implants for breast augmentation? Three year follow-up of a prospective randomised controlled trial.

Malata CM, Feldberg L, Coleman DJ, Foo IT, Sharpe DT.

Br J Plast Surg. 1997 Feb;50(2):99-105.

PMID:
9135425
46.

Dupuytren's disease in children.

Urban M, Feldberg L, Janssen A, Elliot D.

J Hand Surg Br. 1996 Feb;21(1):112-6. Review.

PMID:
8676015
47.

An unusual cause of anuria in a burned child.

Feldberg LE, Salahuddin MJ, Frame JD.

Burns. 1992 Feb;18(1):78-9.

PMID:
1558685
48.

Cement burns and their treatment.

Feldberg L, Regan PJ, Roberts AH.

Burns. 1992 Feb;18(1):51-3.

PMID:
1558676
49.

Accessory palmaris longus muscle causing ulnar nerve compression at the wrist.

Regan PJ, Feldberg L, Bailey BN.

J Hand Surg Am. 1991 Jul;16(4):736-8.

PMID:
1880375
50.

Hand injuries from leading horses.

Regan PJ, Roberts JO, Feldberg L, Roberts AH.

Injury. 1991 Mar;22(2):124-6.

PMID:
2037328

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