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Advancing dengue vaccine development.

Feinberg MB, Ahmed R.

Science. 2017 Nov 17;358(6365):865-866. doi: 10.1126/science.aaq0215. No abstract available.


Robust and sustained immune activation in human Ebola virus infection.

Mandl JN, Feinberg MB.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4518-9. doi: 10.1073/pnas.1503864112. Epub 2015 Apr 7. No abstract available.


Reservoir host immune responses to emerging zoonotic viruses.

Mandl JN, Ahmed R, Barreiro LB, Daszak P, Epstein JH, Virgin HW, Feinberg MB.

Cell. 2015 Jan 15;160(1-2):20-35. doi: 10.1016/j.cell.2014.12.003. Epub 2014 Dec 18. Review.


Accelerating the development of a safe and effective HIV vaccine: HIV vaccine case study for the Decade of Vaccines.

Koff WC, Russell ND, Walport M, Feinberg MB, Shiver JW, Karim SA, Walker BD, McGlynn MG, Nweneka CV, Nabel GJ.

Vaccine. 2013 Apr 18;31 Suppl 2:B204-8. doi: 10.1016/j.vaccine.2012.10.115. Review.


Deletion of specific immune-modulatory genes from modified vaccinia virus Ankara-based HIV vaccines engenders improved immunogenicity in rhesus macaques.

Garber DA, O'Mara LA, Gangadhara S, McQuoid M, Zhang X, Zheng R, Gill K, Verma M, Yu T, Johnson B, Li B, Derdeyn CA, Ibegbu C, Altman JD, Hunter E, Feinberg MB.

J Virol. 2012 Dec;86(23):12605-15. doi: 10.1128/JVI.00246-12. Epub 2012 Sep 12.


Born this way? Understanding the immunological basis of effective HIV control.

Feinberg MB, Ahmed R.

Nat Immunol. 2012 Jun 19;13(7):632-4. doi: 10.1038/ni.2351. No abstract available.


Evaluating the health impact of a public-private partnership: to reduce rotavirus disease in Nicaragua.

Khawaja S, Cardellino A, Klotz D, Kuter BJ, Feinberg MB, Colatrella BD, Mast TC.

Hum Vaccin Immunother. 2012 Jun;8(6):777-82. doi: 10.4161/hv.19757. Epub 2012 Apr 12.


Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques.

Vanderford TH, Bleckwehl C, Engram JC, Dunham RM, Klatt NR, Feinberg MB, Garber DA, Betts MR, Silvestri G.

PLoS Pathog. 2011 May;7(5):e1002048. doi: 10.1371/journal.ppat.1002048. Epub 2011 May 19.


Distinctive TLR7 signaling, type I IFN production, and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host.

Mandl JN, Akondy R, Lawson B, Kozyr N, Staprans SI, Ahmed R, Feinberg MB.

J Immunol. 2011 Jun 1;186(11):6406-16. doi: 10.4049/jimmunol.1001191. Epub 2011 Apr 22.


Role of nonhuman primates in the evaluation of candidate AIDS vaccines: an industry perspective.

Staprans SI, Feinberg MB, Shiver JW, Casimiro DR.

Curr Opin HIV AIDS. 2010 Sep;5(5):377-85. doi: 10.1097/COH.0b013e32833d2e19. Review.


Industry perspectives: ensuring vaccination of children and adolescents without financial barriers.

Feinberg MB, Gordon L.

Pediatrics. 2009 Dec;124 Suppl 5:S563-4. doi: 10.1542/peds.2009-1542Q. No abstract available.


Selective removal of stratum corneum by microdermabrasion to increase skin permeability.

Gill HS, Andrews SN, Sakthivel SK, Fedanov A, Williams IR, Garber DA, Priddy FH, Yellin S, Feinberg MB, Staprans SI, Prausnitz MR.

Eur J Pharm Sci. 2009 Sep 10;38(2):95-103. doi: 10.1016/j.ejps.2009.06.004. Epub 2009 Jun 25.


Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.

Engram JC, Dunham RM, Makedonas G, Vanderford TH, Sumpter B, Klatt NR, Ratcliffe SJ, Garg S, Paiardini M, McQuoid M, Altman JD, Staprans SI, Betts MR, Garber DA, Feinberg MB, Silvestri G.

J Immunol. 2009 Jul 1;183(1):706-17. doi: 10.4049/jimmunol.0803746.


Expanding the repertoire of Modified Vaccinia Ankara-based vaccine vectors via genetic complementation strategies.

Garber DA, O'Mara LA, Zhao J, Gangadhara S, An I, Feinberg MB.

PLoS One. 2009;4(5):e5445. doi: 10.1371/journal.pone.0005445. Epub 2009 May 6.


Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

Mandl JN, Barry AP, Vanderford TH, Kozyr N, Chavan R, Klucking S, Barrat FJ, Coffman RL, Staprans SI, Feinberg MB.

Nat Med. 2008 Oct;14(10):1077-87. doi: 10.1038/nm.1871. Epub 2008 Sep 14.


Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines.

Miller JD, van der Most RG, Akondy RS, Glidewell JT, Albott S, Masopust D, Murali-Krishna K, Mahar PL, Edupuganti S, Lalor S, Germon S, Del Rio C, Mulligan MJ, Staprans SI, Altman JD, Feinberg MB, Ahmed R.

Immunity. 2008 May;28(5):710-22. doi: 10.1016/j.immuni.2008.02.020. Epub 2008 May 8.


Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.

Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, Perelson AS, Feinberg MB, Silvestri G.

J Virol. 2008 Apr;82(7):3725-35. doi: 10.1128/JVI.02408-07. Epub 2008 Jan 23.


Estimating the effectiveness of simian immunodeficiency virus-specific CD8+ T cells from the dynamics of viral immune escape.

Mandl JN, Regoes RR, Garber DA, Feinberg MB.

J Virol. 2007 Nov;81(21):11982-91. Epub 2007 Aug 15.


Multiple immunizations with adenovirus and MVA vectors improve CD8+ T cell functionality and mucosal homing.

Tatsis N, Lin SW, Harris-McCoy K, Garber DA, Feinberg MB, Ertl HC.

Virology. 2007 Oct 10;367(1):156-67. Epub 2007 Jun 27.


Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species.

Barry AP, Silvestri G, Safrit JT, Sumpter B, Kozyr N, McClure HM, Staprans SI, Feinberg MB.

J Immunol. 2007 Jun 15;178(12):8002-12.


Detection of acute HIV infections in an urban HIV counseling and testing population in the United States.

Priddy FH, Pilcher CD, Moore RH, Tambe P, Park MN, Fiscus SA, Feinberg MB, del Rio C.

J Acquir Immune Defic Syndr. 2007 Feb 1;44(2):196-202.


Adaptation of a diverse simian immunodeficiency virus population to a new host is revealed through a systematic approach to identify amino acid sites under selection.

Vanderford TH, Demma LJ, Feinberg MB, Staprans SI, Logsdon JM Jr.

Mol Biol Evol. 2007 Mar;24(3):660-9. Epub 2006 Dec 11.


Probing the possibilities for T-cell-based AIDS vaccines.

Garber DA, Feinberg MB.

Curr Opin HIV AIDS. 2006 Jul;1(4):314-22. doi: 10.1097/01.COH.0000232347.15909.22.


Evolution of the uniquely adaptable lentiviral envelope in a natural reservoir host.

Demma LJ, Vanderford TH, Logsdon JM Jr, Feinberg MB, Staprans SI.

Retrovirology. 2006 Mar 20;3:19.


The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.

Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G.

Blood. 2006 Jul 1;108(1):209-17. Epub 2006 Mar 7.


SIVsm quasispecies adaptation to a new simian host.

Demma LJ, Logsdon JM Jr, Vanderford TH, Feinberg MB, Staprans SI.

PLoS Pathog. 2005 Sep;1(1):e3. Epub 2005 Sep 30.


Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor.

Chahroudi A, Chavan R, Kozyr N, Waller EK, Silvestri G, Feinberg MB.

J Virol. 2005 Aug;79(16):10397-407. Erratum in: J Virol. 2006 Mar;80(6):3126. Koyzr, Natalia [corrected to Kozyr, Natalia].


Preclinical assessment of HIV vaccines and microbicides by repeated low-dose virus challenges.

Regoes RR, Longini IM, Feinberg MB, Staprans SI.

PLoS Med. 2005 Aug;2(8):e249. Epub 2005 Jul 19.


Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases.

Reeves PM, Bommarius B, Lebeis S, McNulty S, Christensen J, Swimm A, Chahroudi A, Chavan R, Feinberg MB, Veach D, Bornmann W, Sherman M, Kalman D.

Nat Med. 2005 Jul;11(7):731-9. Epub 2005 Jun 26. Erratum in: Nat Med. 2005 Dec;11(12):1361.


Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts.

Silvestri G, Fedanov A, Germon S, Kozyr N, Kaiser WJ, Garber DA, McClure H, Feinberg MB, Staprans SI.

J Virol. 2005 Apr;79(7):4043-54.


Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.

Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, Radziewicz H, Piedimonte G, Magnani M, Montroni M, Kaech SM, Weintrob A, Altman JD, Sodora DL, Feinberg MB, Silvestri G.

J Immunol. 2005 Mar 1;174(5):2900-9.


Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein.

Staprans SI, Barry AP, Silvestri G, Safrit JT, Kozyr N, Sumpter B, Nguyen H, McClure H, Montefiori D, Cohen JI, Feinberg MB.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13026-31. Epub 2004 Aug 23.


The roles of nonhuman primates in the preclinical evaluation of candidate AIDS vaccines.

Staprans SI, Feinberg MB.

Expert Rev Vaccines. 2004 Aug;3(4 Suppl):S5-32. Review.


Prospects for an AIDS vaccine: three big questions, no easy answers.

Garber DA, Silvestri G, Feinberg MB.

Lancet Infect Dis. 2004 Jul;4(7):397-413. Review.


Roles of target cells and virus-specific cellular immunity in primary simian immunodeficiency virus infection.

Regoes RR, Antia R, Garber DA, Silvestri G, Feinberg MB, Staprans SI.

J Virol. 2004 May;78(9):4866-75.


Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication.

Garber DA, Silvestri G, Barry AP, Fedanov A, Kozyr N, McClure H, Montefiori DC, Larsen CP, Altman JD, Staprans SI, Feinberg MB.

J Clin Invest. 2004 Mar;113(6):836-45.


HIV escape: there and back again.

Altman JD, Feinberg MB.

Nat Med. 2004 Mar;10(3):229-30. No abstract available.


Assessment of lymphocyte-mediated cytotoxicity using flow cytometry.

Liu L, Packard BZ, Brown MJ, Komoriya A, Feinberg MB.

Methods Mol Biol. 2004;263:125-40.


Public health. A sound rationale needed for phase III HIV-1 vaccine trials.

Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, Picker L, Richman D, Rinaldo C, Stevenson M, Watkins DI, Wolinsky SM, Zack JA.

Science. 2004 Jan 16;303(5656):316. No abstract available.


AIDS vaccine development: the long and winding road.

Garber DA, Feinberg MB.

AIDS Rev. 2003 Jul-Sep;5(3):131-9. Review.


A molecularly cloned Schwarz strain of measles virus vaccine induces strong immune responses in macaques and transgenic mice.

Combredet C, Labrousse V, Mollet L, Lorin C, Delebecque F, Hurtrel B, McClure H, Feinberg MB, Brahic M, Tangy F.

J Virol. 2003 Nov;77(21):11546-54.


Turnover of lymphocytes and conceptual paradigms in HIV infection.

Silvestri G, Feinberg MB.

J Clin Invest. 2003 Sep;112(6):821-4.


Measuring T cell-mediated cytotoxicity using fluorogenic caspase substrates.

Chahroudi A, Silvestri G, Feinberg MB.

Methods. 2003 Oct;31(2):120-6. Review.


Suppression of cerebrospinal fluid HIV burden in antiretroviral naive patients on a potent four-drug antiretroviral regimen.

Polis MA, Suzman DL, Yoder CP, Shen JM, Mican JM, Dewar RL, Metcalf JA, Falloon J, Davey RT Jr, Kovacs JA, Feinberg MB, Masur H, Piscitelli SC.

AIDS. 2003 May 23;17(8):1167-72.


Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

Silvestri G, Sodora DL, Koup RA, Paiardini M, O'Neil SP, McClure HM, Staprans SI, Feinberg MB.

Immunity. 2003 Mar;18(3):441-52.


HIV tropism and CD4+ T-cell depletion.

Feinberg MB, McCune JM, Miedema F, Moore JP, Schuitemaker H.

Nat Med. 2002 Jun;8(6):537. No abstract available.


AIDS vaccine models: challenging challenge viruses.

Feinberg MB, Moore JP.

Nat Med. 2002 Mar;8(3):207-10. No abstract available.


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